E. Correia, Larissa Ventura Ribeiro Bruscky, B. C. O. Valério, A. C. Murta, Fabiano de Castro Albrecht, I. Pinto, P. Smanio
{"title":"Recurrent Syncope: Initial Presentation of Transthyretin Amyloidosis. Benefits of Disease-Modifying Treatment","authors":"E. Correia, Larissa Ventura Ribeiro Bruscky, B. C. O. Valério, A. C. Murta, Fabiano de Castro Albrecht, I. Pinto, P. Smanio","doi":"10.36660/abchf.20210014","DOIUrl":"https://doi.org/10.36660/abchf.20210014","url":null,"abstract":"","PeriodicalId":277175,"journal":{"name":"ABC: Heart Failure & Cardiomyopathy","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129769070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Indications for Anticoagulation in Cardiac Amyloidosis","authors":"M. W. Montera","doi":"10.36660/abchf.20210032","DOIUrl":"https://doi.org/10.36660/abchf.20210032","url":null,"abstract":"In cardiac amyloidosis, amyloid infiltrate at the atrial level promotes atrial dilation and contractile dysfunction as well as a higher prevalence of atrial fibrillation which, when associated with ventricular diastolic and systolic dysfunction, favors blood stasis and the consequent development of intracardiac thrombosis (ICT) and cardioembolic events. In a study of 116 autopsies of patients with cardiac amyloidosis, conducted at the Mayo Clinic, the presence of ICT was demonstrated in 33% of hearts, with a significantly higher prevalence in patients with the AL form of amyloidosis than in those with other forms (56% versus 16%, p < 0.001).1 When evaluating 324 patients with cardiac amyloidosis using cardiac magnetic resonance, we found an ICT prevalence of 6.2%, with 90% located in the atrial appendage. Among the patients, 70% had atrial fibrillation, and 30% had sinus rhythm, with a similar prevalence of ICT in the AL (5.2%) and ATTR forms (7.2%).2,3 Morphological and functional changes caused by atrial amyloid infiltrate favor the development of atrial fibrillation, with a prevalence ranging from 29% to 60%, depending on the population, and it is more prevalent in the ATTR form, given that it affects an older population. The presence of atrial fibrillation poses a high risk for the development of ICT and stroke, especially in patients with AL amyloidosis.4 Approximately 20% to 30% of patients who have ICT, as well as 27% of patients with cerebral ischemic events are in sinus rhythm.3,5 The probable mechanism respons ib le for the development of thrombotic events and thromboembolism in patients in sinus rhythm would be the presence of atrial myopathy due to amyloid infiltrate and high ventricular filling pressures, which induce atrial contractile dysfunction and favor blood stasis and ICT formation.5-7 By means of logistic regression analysis, several factors have been ident i f ied that are re lated to greater predisposition to ICT and thromboembolic","PeriodicalId":277175,"journal":{"name":"ABC: Heart Failure & Cardiomyopathy","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125764625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. C. Danzmann, João Ricardo Cambruzzi Zimmer, Anna Tscheika
{"title":"Heart Failure with Preserved Ejection Fraction and Cardiac Amyloidosis: Implications for Treatment","authors":"L. C. Danzmann, João Ricardo Cambruzzi Zimmer, Anna Tscheika","doi":"10.36660/abchf.20210033","DOIUrl":"https://doi.org/10.36660/abchf.20210033","url":null,"abstract":"","PeriodicalId":277175,"journal":{"name":"ABC: Heart Failure & Cardiomyopathy","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117017439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Fernandes, C. Cafezeiro, Renata do Val, Alexandra Patrícia Zilli Vieira, Wilson Marques, E. B. Correia, A. Carvalho, A. Chagas, A. Oliveira, P. Souza, W. B. Pinto, A. Macedo, M. Antunes, P. Schwartzmann, S. Mangini, M. Simões
{"title":"Registry of Transthyretin Amyloidosis in the State of São Paulo (REACT-SP)","authors":"F. Fernandes, C. Cafezeiro, Renata do Val, Alexandra Patrícia Zilli Vieira, Wilson Marques, E. B. Correia, A. Carvalho, A. Chagas, A. Oliveira, P. Souza, W. B. Pinto, A. Macedo, M. Antunes, P. Schwartzmann, S. Mangini, M. Simões","doi":"10.36660/abchf.20210028","DOIUrl":"https://doi.org/10.36660/abchf.20210028","url":null,"abstract":"","PeriodicalId":277175,"journal":{"name":"ABC: Heart Failure & Cardiomyopathy","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117107862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Kirschbaum, Aristóteles Conte Alencar, V. E. Rosa, F. Ramires, A. Abizaid, F. Brito, F. Tarasoutchi, R. Kalil, F. Fernandes
{"title":"Cardiac Amyloidosis and Aortic Stenosis: When to Consider it and How to Treat it?","authors":"M. Kirschbaum, Aristóteles Conte Alencar, V. E. Rosa, F. Ramires, A. Abizaid, F. Brito, F. Tarasoutchi, R. Kalil, F. Fernandes","doi":"10.36660/abchf.20210027","DOIUrl":"https://doi.org/10.36660/abchf.20210027","url":null,"abstract":"","PeriodicalId":277175,"journal":{"name":"ABC: Heart Failure & Cardiomyopathy","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125548705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Silva, C. Montenegro, Marcelo Melo, L. Ritt, André Luiz Cerqueira Almeida
{"title":"New Paradigms in Cardiac Amyloidosis: The Current Experience of the Northeast Region of Brazil","authors":"T. Silva, C. Montenegro, Marcelo Melo, L. Ritt, André Luiz Cerqueira Almeida","doi":"10.36660/abchf.20210013","DOIUrl":"https://doi.org/10.36660/abchf.20210013","url":null,"abstract":"","PeriodicalId":277175,"journal":{"name":"ABC: Heart Failure & Cardiomyopathy","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129297930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. C. Danzmann, E. Belyavskiy, Antônio José Lagoeiro Jorge, E. Mesquita, M. Torres
{"title":"The Challenge of HFpEF Diagnosis in Brazil","authors":"L. C. Danzmann, E. Belyavskiy, Antônio José Lagoeiro Jorge, E. Mesquita, M. Torres","doi":"10.36660/abchf.20210011","DOIUrl":"https://doi.org/10.36660/abchf.20210011","url":null,"abstract":"Heart failure with preserved ejection fraction (HFpEF) is highly prevalent in Brazil and worldwide. However, the recent diagnostic criteria for this condition are complex and difficult to apply in the Brazilian health system. This review proposes adapting the modern diagnostic criteria to the needs of each patient, from the primary care to the most complex one, using a system of three steps of complexity and highlighting the importance of searching specific disease etiology. Heart failure with preserved ejection fraction (HFpEF) remains a major public health problem worldwide and also in Brazil. 1 The recognition and diagnosis of this syndrome remain a challenge, due to its physiopathological complexity and phenotypic diversity. The current scientific evidence on etiopathogenesis provided more accurate diagnostic recommendations but requires comprehensive echocardiographic analysis. 2,3 A recently published recommendation from the Heart Failure Association of the European Society of Cardiology (HFA-ESC) brought a comprehensive overview and an algorithm for the diagnosis of HFpEF. 4","PeriodicalId":277175,"journal":{"name":"ABC: Heart Failure & Cardiomyopathy","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130340921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How to Treat Heart Failure in Patients with Cardiac Amyloidosis","authors":"F. Marcondes-Braga, C. Aragão","doi":"10.36660/abchf.20210031","DOIUrl":"https://doi.org/10.36660/abchf.20210031","url":null,"abstract":"","PeriodicalId":277175,"journal":{"name":"ABC: Heart Failure & Cardiomyopathy","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125559998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardiac Magnetic Resonance and Amyloidosis: How can it Assist Clinical Reasoning?","authors":"I. Pinto","doi":"10.36660/abchf.20210016","DOIUrl":"https://doi.org/10.36660/abchf.20210016","url":null,"abstract":"","PeriodicalId":277175,"journal":{"name":"ABC: Heart Failure & Cardiomyopathy","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127795477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}