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Efficiency in Natural Product Total Synthesis最新文献

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Natural Product Synthesis for Drug Discovery and Chemical Biology 用于药物发现和化学生物学的天然产物合成
Efficiency in Natural Product Total Synthesis Pub Date : 2018-08-06 DOI: 10.1002/9781118940228.CH10
Z. Yao, Wanguo Wei
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引用次数: 0
Index 指数
Efficiency in Natural Product Total Synthesis Pub Date : 2018-08-06 DOI: 10.1002/9781118940228.index
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引用次数: 0
C-H Activation-Based Strategy for Natural Product Synthesis 基于C-H活化的天然产物合成策略
Efficiency in Natural Product Total Synthesis Pub Date : 2018-08-06 DOI: 10.1002/9781118940228.CH5
H. Zhai, Yun Li, F. Fang
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引用次数: 1
Recent Applications of Kagan's Reagent (SmI2) in Natural Product Synthesis Kagan试剂(SmI2)在天然产物合成中的最新应用
Efficiency in Natural Product Total Synthesis Pub Date : 2018-08-06 DOI: 10.1002/9781118940228.CH6
Erica Benedetti, Cyril Bressy, Michael Smietana, S. Arseniyadis
{"title":"Recent Applications of Kagan's Reagent (SmI2) in Natural Product Synthesis","authors":"Erica Benedetti, Cyril Bressy, Michael Smietana, S. Arseniyadis","doi":"10.1002/9781118940228.CH6","DOIUrl":"https://doi.org/10.1002/9781118940228.CH6","url":null,"abstract":"","PeriodicalId":270145,"journal":{"name":"Efficiency in Natural Product Total Synthesis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117073352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Renewable Resource-Based Building Blocks/Chirons for the Total Synthesis of Natural Products 基于可再生资源的天然产物全合成的构建模块/Chirons
Efficiency in Natural Product Total Synthesis Pub Date : 2018-08-06 DOI: 10.1002/9781118940228.CH9
Wai-Lung Ng, A. Wong, T. Shing
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引用次数: 2
Asymmetric Organocatalysis in the Total Synthesis of Complex Natural Products 复杂天然产物全合成中的不对称有机催化
Efficiency in Natural Product Total Synthesis Pub Date : 2018-08-06 DOI: 10.1002/9781118940228.CH7
Gang Zhao, Zhengqing Ye, Xiao Yu Wu
{"title":"Asymmetric Organocatalysis in the Total Synthesis of Complex Natural Products","authors":"Gang Zhao, Zhengqing Ye, Xiao Yu Wu","doi":"10.1002/9781118940228.CH7","DOIUrl":"https://doi.org/10.1002/9781118940228.CH7","url":null,"abstract":"","PeriodicalId":270145,"journal":{"name":"Efficiency in Natural Product Total Synthesis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121735523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Diels-Alder Cascades in Natural Product Total Synthesis 天然产物全合成中的Diels-Alder级联
Efficiency in Natural Product Total Synthesis Pub Date : 2018-08-06 DOI: 10.1002/9781118940228.CH3
R. Hsung, Zhi-Xiong Ma, Lichao Fang, John B. Feltenberger
{"title":"Diels-Alder Cascades in Natural Product Total Synthesis","authors":"R. Hsung, Zhi-Xiong Ma, Lichao Fang, John B. Feltenberger","doi":"10.1002/9781118940228.CH3","DOIUrl":"https://doi.org/10.1002/9781118940228.CH3","url":null,"abstract":"","PeriodicalId":270145,"journal":{"name":"Efficiency in Natural Product Total Synthesis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125398136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Principles for Synthetic Efficiency and Expansion of the Field 综合效率和领域扩展原理
Efficiency in Natural Product Total Synthesis Pub Date : 2018-08-06 DOI: 10.1002/9781118940228.CH1
Pei‐Qiang Huang
{"title":"Principles for Synthetic Efficiency and Expansion of the Field","authors":"Pei‐Qiang Huang","doi":"10.1002/9781118940228.CH1","DOIUrl":"https://doi.org/10.1002/9781118940228.CH1","url":null,"abstract":"Today, the field of natural product total synthesis, which was once a dominant sub‐discipline of organic chemistry, has lost its prime position. Even with the renaissance of natural products as drug candidates, and the recent recognition of the value and contribution of natural product‐based drugs to societies by the Nobel Prize in Physiology or Medicine 2015, the situation has changed. As we have mentioned in the Introduction, “it is estimated that half of the top 100 best‐selling medications will soon be biologics.” According to Dirk Trauner, “the field is currently under fire, at least in societies that have traditionally supported it.” To address these challenges, we need to significantly improve efficiency of the synthesis, expand the field of total synthesis, and address the concerns of society. In this chapter, the efforts by chemists from these dimensions will be summarized with a focus on concepts.","PeriodicalId":270145,"journal":{"name":"Efficiency in Natural Product Total Synthesis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123179437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Selected Procedure-Economical Enantioselective Total Syntheses of Natural Products 精选程序-天然产物的经济对映选择性全合成
Efficiency in Natural Product Total Synthesis Pub Date : 2018-08-06 DOI: 10.1002/9781118940228.CH2
Pei‐Qiang Huang
{"title":"Selected Procedure-Economical Enantioselective Total Syntheses of Natural Products","authors":"Pei‐Qiang Huang","doi":"10.1002/9781118940228.CH2","DOIUrl":"https://doi.org/10.1002/9781118940228.CH2","url":null,"abstract":"","PeriodicalId":270145,"journal":{"name":"Efficiency in Natural Product Total Synthesis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114491524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concluding Remarks and Perspectives 结束语及观点
Efficiency in Natural Product Total Synthesis Pub Date : 2018-08-06 DOI: 10.1002/9781118940228.CH12
Pei‐Qiang Huang, R. Hsung, Zhi-Xiong Ma, Z. Yao
{"title":"Concluding Remarks and Perspectives","authors":"Pei‐Qiang Huang, R. Hsung, Zhi-Xiong Ma, Z. Yao","doi":"10.1002/9781118940228.CH12","DOIUrl":"https://doi.org/10.1002/9781118940228.CH12","url":null,"abstract":"","PeriodicalId":270145,"journal":{"name":"Efficiency in Natural Product Total Synthesis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128792371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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