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Biological and Pharmaceutical Bulletin最新文献

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Enhancing Corneal Drug Penetration Using Penetratin for Ophthalmic Suspensions 使用眼科悬浮剂 Penetratin 增强角膜药物穿透力
Biological and Pharmaceutical Bulletin Pub Date : 2024-05-25 DOI: 10.1248/bpb.b24-00077
Ryo Morofuji, Kazuhiro Kudo, Takahiro Honda, Shino Kinugasa, Takamasa Matsuo, Komei Okabe
{"title":"Enhancing Corneal Drug Penetration Using Penetratin for Ophthalmic Suspensions","authors":"Ryo Morofuji, Kazuhiro Kudo, Takahiro Honda, Shino Kinugasa, Takamasa Matsuo, Komei Okabe","doi":"10.1248/bpb.b24-00077","DOIUrl":"https://doi.org/10.1248/bpb.b24-00077","url":null,"abstract":"","PeriodicalId":262210,"journal":{"name":"Biological and Pharmaceutical Bulletin","volume":"17 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141098439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short-Term Preexposure to Novel Enriched Environment Augments Hippocampal Ripples in Urethane-Anesthetized Mice 短期暴露于新颖的富集环境可增强尿烷麻醉小鼠的海马纹波
Biological and Pharmaceutical Bulletin Pub Date : 2024-05-24 DOI: 10.1248/bpb.b24-00118
Rio Okada, Yuji Ikegaya, Nobuyoshi Matsumoto
{"title":"Short-Term Preexposure to Novel Enriched Environment Augments Hippocampal Ripples in Urethane-Anesthetized Mice","authors":"Rio Okada, Yuji Ikegaya, Nobuyoshi Matsumoto","doi":"10.1248/bpb.b24-00118","DOIUrl":"https://doi.org/10.1248/bpb.b24-00118","url":null,"abstract":"","PeriodicalId":262210,"journal":{"name":"Biological and Pharmaceutical Bulletin","volume":"2 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141099917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modeled Hepatic/Plasma Exposures of Omeprazole Prescribed Alone in Cytochrome P450 2C19 Poor Metabolizers Are Likely Associated with Hepatic Toxicity Reported in a Japanese Adverse Event Database 细胞色素 P450 2C19 低代谢者单用奥美拉唑的模型肝脏/血浆暴露量可能与日本不良事件数据库中报告的肝脏毒性有关
Biological and Pharmaceutical Bulletin Pub Date : 2024-05-24 DOI: 10.1248/bpb.b24-00145
K. Adachi, K. Ohyama, Yoichi Tanaka, N. Murayama, M. Shimizu, Yoshiro Saito, Hiroshi Yamazaki
{"title":"Modeled Hepatic/Plasma Exposures of Omeprazole Prescribed Alone in Cytochrome P450 2C19 Poor Metabolizers Are Likely Associated with Hepatic Toxicity Reported in a Japanese Adverse Event Database","authors":"K. Adachi, K. Ohyama, Yoichi Tanaka, N. Murayama, M. Shimizu, Yoshiro Saito, Hiroshi Yamazaki","doi":"10.1248/bpb.b24-00145","DOIUrl":"https://doi.org/10.1248/bpb.b24-00145","url":null,"abstract":"","PeriodicalId":262210,"journal":{"name":"Biological and Pharmaceutical Bulletin","volume":"2 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141098601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk Factors for Teicoplanin-Associated Acute Kidney Injury in Patients with Hematological Malignancies: Focusing on Concomitant Use of Tazobactam/Piperacillin 血液恶性肿瘤患者发生替考拉宁相关急性肾损伤的风险因素：关注他唑巴坦/哌拉西林的同时使用
Biological and Pharmaceutical Bulletin Pub Date : 2024-05-18 DOI: 10.1248/bpb.b23-00848
Yuko Morinaga, Ryota Tanaka, R. Tatsuta, K. Takano, Takehiro Hashimoto, Masao Ogata, Kazufumi Hiramatsu, Hiroki Itoh
{"title":"Risk Factors for Teicoplanin-Associated Acute Kidney Injury in Patients with Hematological Malignancies: Focusing on Concomitant Use of Tazobactam/Piperacillin","authors":"Yuko Morinaga, Ryota Tanaka, R. Tatsuta, K. Takano, Takehiro Hashimoto, Masao Ogata, Kazufumi Hiramatsu, Hiroki Itoh","doi":"10.1248/bpb.b23-00848","DOIUrl":"https://doi.org/10.1248/bpb.b23-00848","url":null,"abstract":"","PeriodicalId":262210,"journal":{"name":"Biological and Pharmaceutical Bulletin","volume":"17 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computational Estimation of Residues Involving Resistance to the SARS-CoV-2 Main Protease Inhibitor Ensitrelvir Based on Virtual Alanine Scan of the Active Site 基于活性位点虚拟丙氨酸扫描的 SARS-CoV-2 主要蛋白酶抑制剂 Ensitrelvir 抗药性相关残基的计算估计
Biological and Pharmaceutical Bulletin Pub Date : 2024-05-17 DOI: 10.1248/bpb.b24-00031
Ayato Mizuno, Tomoki Nakayoshi, Koichi Kato, Eiji Kurimoto, Akifumi Oda
{"title":"Computational Estimation of Residues Involving Resistance to the SARS-CoV-2 Main Protease Inhibitor Ensitrelvir Based on Virtual Alanine Scan of the Active Site","authors":"Ayato Mizuno, Tomoki Nakayoshi, Koichi Kato, Eiji Kurimoto, Akifumi Oda","doi":"10.1248/bpb.b24-00031","DOIUrl":"https://doi.org/10.1248/bpb.b24-00031","url":null,"abstract":"","PeriodicalId":262210,"journal":{"name":"Biological and Pharmaceutical Bulletin","volume":"3 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140962258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ciclesonide Inhibits SARS-CoV-2 Papain-Like Protease in Vitro 环索奈德在体外抑制 SARS-CoV-2 Papain 类蛋白酶
Biological and Pharmaceutical Bulletin Pub Date : 2024-05-17 DOI: 10.1248/bpb.b24-00038
Yuka Kiba, Takashi Tanikawa, Masashi Kitamura
{"title":"Ciclesonide Inhibits SARS-CoV-2 Papain-Like Protease in Vitro","authors":"Yuka Kiba, Takashi Tanikawa, Masashi Kitamura","doi":"10.1248/bpb.b24-00038","DOIUrl":"https://doi.org/10.1248/bpb.b24-00038","url":null,"abstract":"","PeriodicalId":262210,"journal":{"name":"Biological and Pharmaceutical Bulletin","volume":"12 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140962192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Causes of Sex Differences in Serum Cholesterol and Triglyceride Levels in Meishan Pigs 眉山猪血清胆固醇和甘油三酯水平性别差异的原因
Biological and Pharmaceutical Bulletin Pub Date : 2024-03-08 DOI: 10.1248/bpb.b23-00895
M. Kojima, Masakuni Degawa
{"title":"Causes of Sex Differences in Serum Cholesterol and Triglyceride Levels in Meishan Pigs","authors":"M. Kojima, Masakuni Degawa","doi":"10.1248/bpb.b23-00895","DOIUrl":"https://doi.org/10.1248/bpb.b23-00895","url":null,"abstract":"","PeriodicalId":262210,"journal":{"name":"Biological and Pharmaceutical Bulletin","volume":"47 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140077170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the Effectiveness of Vedolizumab and Ustekinumab in Crohn’s Disease Patients Who Failed Anti-tumor Necrosis Factor-α Treatment in Japan: An Observational Study Utilizing Claims Database 日本抗肿瘤坏死因子-α治疗失败的克罗恩病患者使用维多珠单抗和优思妥单抗的疗效比较：利用索赔数据库的观察性研究
Biological and Pharmaceutical Bulletin Pub Date : 2024-02-16 DOI: 10.1248/bpb.b23-00847
Minoru Shimazaki, Yutaka Matsuyama, Daisuke Koide
{"title":"Comparison of the Effectiveness of Vedolizumab and Ustekinumab in Crohn’s Disease Patients Who Failed Anti-tumor Necrosis Factor-α Treatment in Japan: An Observational Study Utilizing Claims Database","authors":"Minoru Shimazaki, Yutaka Matsuyama, Daisuke Koide","doi":"10.1248/bpb.b23-00847","DOIUrl":"https://doi.org/10.1248/bpb.b23-00847","url":null,"abstract":"","PeriodicalId":262210,"journal":{"name":"Biological and Pharmaceutical Bulletin","volume":"4 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139773889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel Screening System for Biliary Excretion of Drugs Using Human Cholangiocyte Organoid Monolayers with Directional Drug Transport 利用具有药物定向运输功能的人胆管细胞器单体的新型药物胆汁排泄筛选系统
Biological and Pharmaceutical Bulletin Pub Date : 2024-02-16 DOI: 10.1248/bpb.b23-00655
Kenta Mizoi, Ryo Okada, Arisa Mashimo, Norio Masuda, Manabu Itoh, Seiichi Ishida, Daiju Yamazaki, T. Ogihara
{"title":"Novel Screening System for Biliary Excretion of Drugs Using Human Cholangiocyte Organoid Monolayers with Directional Drug Transport","authors":"Kenta Mizoi, Ryo Okada, Arisa Mashimo, Norio Masuda, Manabu Itoh, Seiichi Ishida, Daiju Yamazaki, T. Ogihara","doi":"10.1248/bpb.b23-00655","DOIUrl":"https://doi.org/10.1248/bpb.b23-00655","url":null,"abstract":"","PeriodicalId":262210,"journal":{"name":"Biological and Pharmaceutical Bulletin","volume":"323 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139833365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potent Efficacy of 3-Amino-4-hydroxy Benzoic Acid, a Small Molecule Having Anti-fibrotic Activity, in a Mouse Model of Non-alcoholic Steatohepatitis 一种具有抗纤维化活性的小分子--3-氨基-4-羟基苯甲酸在非酒精性脂肪性肝炎小鼠模型中的强效作用
Biological and Pharmaceutical Bulletin Pub Date : 2024-02-16 DOI: 10.1248/bpb.b23-00771
Tomoaki Yamaguchi, K. Shibata, Keiji Hasumi, K. Nobe
{"title":"Potent Efficacy of 3-Amino-4-hydroxy Benzoic Acid, a Small Molecule Having Anti-fibrotic Activity, in a Mouse Model of Non-alcoholic Steatohepatitis","authors":"Tomoaki Yamaguchi, K. Shibata, Keiji Hasumi, K. Nobe","doi":"10.1248/bpb.b23-00771","DOIUrl":"https://doi.org/10.1248/bpb.b23-00771","url":null,"abstract":"","PeriodicalId":262210,"journal":{"name":"Biological and Pharmaceutical Bulletin","volume":"344 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139833383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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