N. Kolotilov, A. Alekseenko, I. Andrushchenko, S. Antón
{"title":"Repurposing of Drugs: Radiological Aspect","authors":"N. Kolotilov, A. Alekseenko, I. Andrushchenko, S. Antón","doi":"10.37336/2707-0700-2019-3-7","DOIUrl":"https://doi.org/10.37336/2707-0700-2019-3-7","url":null,"abstract":"Repurposing or re-positioning of drugs applied in medical practice is a trend under a new adequate and clearly understood term that existed before (for example, application of known drugs for a new purpose).\u0000The purpose of the article is to state, within the framework of repurposing and future sudden relevance and demand, the information on budget drugs for a long-term maintaining of increased body radioresistance.\u0000Drugs for the long-term maintenance of increased body radioresistance are described: riboxin and succinic acid. The possibility of long-term administration is an important advantage of riboxin and succinic acid. The knowledge of the full real spectrum of available drugs, undoubtedly, allows prevention of polypharmacy and conservation of economic resources.","PeriodicalId":262112,"journal":{"name":"Radiation Diagnostics, Radiation Therapy","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126319527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic support of radiosurgery at brain metastases","authors":"A. Gryazov, I. Dykan, N. Kolotilov","doi":"10.37336/2707-0700-2019-3-6","DOIUrl":"https://doi.org/10.37336/2707-0700-2019-3-6","url":null,"abstract":"The literature review covers 70 sources from 2001-2018. The informativeness of the main radiological neuroimaging technologies is described – magnetic resonance imaging (MRI), multi-detector computed tomography (MDCT), single-photon emission computed tomography; positron emission computed tomography) in determining the early response to stereotactic radiosurgery (SRS) of brain metastases, in predicting effective radiosurgery, volumetric regression, in assessing the state of diffusion processes and microcirculation (tissue perfusion) of irradiated foci.\u0000The diagnostic effectiveness of MRI and MDCT technologies in the differential diagnosis of metastastatic process in the brain recurrence, disease pseudoprogression, and radionecrosis after SRS is presented.\u0000An algorithm for the optimal diagnostic support of patients after SRS of brain metastases is described. The general medical phenomenon of the fundamental irreproducibility of cancer research results is indicated.","PeriodicalId":262112,"journal":{"name":"Radiation Diagnostics, Radiation Therapy","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129003662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}