Open Access Journal of Microbiology & Biotechnology最新文献_第5页

Association between Weight, Body Mass Index, and Breast Cancer Stage in Iranian Women 伊朗妇女体重、身体质量指数与乳腺癌分期之间的关系

Open Access Journal of Microbiology & Biotechnology Pub Date : 2022-10-04 DOI: 10.23880/oajmb-16000245

Zarei A

{"title":"Association between Weight, Body Mass Index, and Breast Cancer Stage in Iranian Women","authors":"Zarei A","doi":"10.23880/oajmb-16000245","DOIUrl":"https://doi.org/10.23880/oajmb-16000245","url":null,"abstract":"Introduction: Breast cancer is a type of cancer developed in the breast organ. Breast cancer occurs when breast tissue cells get out of the control of the cell cycle checkpoints and proliferate abnormally. Breast cancer rates are rising in developing Asian countries, especially Iran. Identifying people with early-stage breast cancer is of great importance, as it can prevent death. Materials & Methods: Data were extracted on the variables of height, weight, breast cancer stage, and body mass index (BMI) related to 109 female patients under treatment for breast cancer who had visited Namazi hospital, Shiraz, during the early stages of the symptoms between the years 2017-2019. In this study, the ANOVA test was used to compare the mean BMI scores at different breast cancer stages. Results: Our results showed a significant difference between mean BMI and breast cancer stage. As the stage of breast cancer in patients increased, the BMI increased as well. Entering advanced stages of breast cancer greatly increased the BMI. Age had no effect on the increase or decrease of BMI. Individuals with BMIs above 30 had stages 3 and 4 of breast cancer (P≤0.5). Discussion: Increased BMI and obesity are prognostic factors for advanced breast cancer stages and the mortality resulting from it. Therefore, early detection of the disease is an essential factor for prevention.","PeriodicalId":257510,"journal":{"name":"Open Access Journal of Microbiology & Biotechnology","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132619906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fungi between Immunostimulatory and Immunosuppressive 真菌的免疫刺激和免疫抑制

Open Access Journal of Microbiology & Biotechnology Pub Date : 2022-10-04 DOI: 10.23880/oajmb-16000239

Elkhateeb Wa

引用次数: 0

In Silico Prediction of Small Open Reading Frames from Intergenic Regions of Cucumis sativus L. Var. Hardwickii 黄瓜基因间区小开放阅读框的计算机预测

Open Access Journal of Microbiology & Biotechnology Pub Date : 2022-10-04 DOI: 10.23880/oajmb-16000242

Teo Ch

引用次数: 1

Molecular Markers in Breeding of Crops: Recent Progress and Advancements 分子标记在作物育种中的应用进展

Open Access Journal of Microbiology & Biotechnology Pub Date : 2022-10-04 DOI: 10.23880/oajmb-16000244

Gudeta Dida

{"title":"Molecular Markers in Breeding of Crops: Recent Progress and Advancements","authors":"Gudeta Dida","doi":"10.23880/oajmb-16000244","DOIUrl":"https://doi.org/10.23880/oajmb-16000244","url":null,"abstract":"A convectional plant breeder faces the challenge of how to more effectively and efficiently perform selection and accelerate breeding progress to satisfy the requirements of changing demands for crop cultivars. However, with the development and advancement of molecular marker technology, the fate of plant breeding has shifted from year to year. Recently, different types of molecular markers have been developed, and advancements in sequencing technologies have greatly increased plant improvement. To further our understanding of molecular markers, several reviews have been published in recent decades. However, with the advancement of newly emerging technologies and techniques, the reviewers did not discuss several recently emerged technologies and techniques in plant breeding. Therefore, this article is intended to be reviewed as an overview of recent breakthroughs in DNA markers and their applications in breeding of crops for early and senior researchers with little or no experience with molecular markers. The progress made in molecular plant breeding, genetics, genomic selection, gene pyramiding, MAS, and gene mapping has contributed to a deeper understanding of molecular markers, provided deeper insights into the variability available for crops, and considerably supplemented current breeding techniques. Next-generation sequencing technologies assist in the identification of novel molecular markers for complex and unstructured populations through genotyping-by-sequencing, gene mapping, QTL mapping, and association mapping. Altogether, the classification of molecular markers and their potential application in plants are discussed.","PeriodicalId":257510,"journal":{"name":"Open Access Journal of Microbiology & Biotechnology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115245912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

High-Speed and High-Pressure Homogenization Techniques for Optimization of Food Processing, Quality, and Safety 优化食品加工、质量和安全的高速和高压均质技术

Open Access Journal of Microbiology & Biotechnology Pub Date : 2022-10-04 DOI: 10.23880/oajmb-16000243

Rania I.M. Almoselhy

{"title":"High-Speed and High-Pressure Homogenization Techniques for Optimization of Food Processing, Quality, and Safety","authors":"Rania I.M. Almoselhy","doi":"10.23880/oajmb-16000243","DOIUrl":"https://doi.org/10.23880/oajmb-16000243","url":null,"abstract":"The current review presents the advantages and health benefits of the fast growing homogenization techniques for improving food processing using the high-speed homogenization (HSH) and the high-pressure homogenization (HPH) to overcome the main problems encountering food manufacturers, merchandizers and end consumers which are the short shelf-life or nonconformity of food products. HSH and HPH are considered as an efficient alternative tool to thermal processes that cause many undesirable effects such as nonenzymatic browning (NEB), off-flavor or degradation of bioactive components. HPH treatment contributes to microbial load reduction and enzyme inactivation with increase of functionality in terms of health effect by increasing bioavailability by favoring the release of bioactive compounds, modified structures of biopolymers with improvement of novel interactions within particles networking. Homogenizers vary according to the purpose needed to achieve. Laboratory Homogenizers provide research and development (R&D) scientists with more experimentation options and capabilities for emulsions, dispersions, cell rupture, and liposomes with the capability of innovations, improve existing products, and more efficient manufacturing. While the Pilot and Industrial Homogenizers offer unique flexibility to meet every customer’s particular requirements in reproducing the same product quality as developed in the laboratory with increasingly higher levels of plant integration with complete automation, controls and data acquisition. Many laboratory and industrial applications were cited here to highlight the significance of this powerful technology.","PeriodicalId":257510,"journal":{"name":"Open Access Journal of Microbiology & Biotechnology","volume":"238 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122052723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Effective Bioconversion of Lignocellulosic Waste to Biodegradable Products for a Cleaner Earth 木质纤维素废物有效生物转化为生物可降解产品，为更清洁的地球

Open Access Journal of Microbiology & Biotechnology Pub Date : 2022-07-04 DOI: 10.23880/oajmb-16000230

N. P, K. I, D. B

{"title":"Effective Bioconversion of Lignocellulosic Waste to Biodegradable Products for a Cleaner Earth","authors":"N. P, K. I, D. B","doi":"10.23880/oajmb-16000230","DOIUrl":"https://doi.org/10.23880/oajmb-16000230","url":null,"abstract":"Earth is constantly subjected to dramatic changes due to uncontrolled human activities and this has led to climatic variations associated with global warming resulting in unparalleled greenhouse gas emissions. One of the major causes is solid waste accumulation by human activities ranging from agricultural to industrial activities. The relation between solid waste and climatic change had forced scientists to propose a solid waste management plan to reuse, recycle and create energy from solid waste preventing its accumulation and subsequent pollution. When we consider human activities which are environmentally hazardous; plastic waste accumulation, agricultural wastes disposal and fossil fuel burning holds prominent positions. Plastic wastes. The accumulation of plastic wastes and agricultural wastes pose serious problems of disposal. Plastic wastes are often incinerated or left to be dumped in landfills. Similarly, agricultural wastes are also burnt, releasing a lot of toxic gases into the atmosphere. A common solution to curb both the problems is to streamline the production of bioplastic using agricultural waste (mostly lignocellulose) as a substrate. The third major environmental threat is the increased motor vehicle emission leading to air pollution associated with health threat. The extent of risk ranges from carcinogenic and noncarcinogenic health effects. Carbon dioxide emission by the increasing use of fossil fuels by ever increasing world population not only depletes the resource but also will result in anthropogenic climate change. Therefore, utilization of lignocellulosic waste material as raw material for monomers for bioplastic as well as for bioethanol production can be considered as a productive approach to address all the three problems mentioned above. In addition utilization of fermentation residue after bio products extraction can be used as a soil enriching agent. The intention is converting lignocellulosic waste to zero waste.","PeriodicalId":257510,"journal":{"name":"Open Access Journal of Microbiology & Biotechnology","volume":"332 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116444727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Strengths and Weaknesses of Methods for Determination of Hyaluronan Molecular Weight 透明质酸分子量测定方法的优缺点

Open Access Journal of Microbiology & Biotechnology Pub Date : 2022-07-04 DOI: 10.23880/oajmb-16000237

K. M.

引用次数: 0

Vaccine-Induced Immune Thrombotic Thrombocytopenia: Where does The PF4 Fit? 疫苗诱导的免疫性血栓性血小板减少症:PF4适用于哪里?

Open Access Journal of Microbiology & Biotechnology Pub Date : 2022-07-04 DOI: 10.23880/oajmb-16000233

Costa Rc, Castro-Faria-Neto Hc, Azevedo Ms, Dalina Am

{"title":"Vaccine-Induced Immune Thrombotic Thrombocytopenia: Where does The PF4 Fit?","authors":"Costa Rc, Castro-Faria-Neto Hc, Azevedo Ms, Dalina Am","doi":"10.23880/oajmb-16000233","DOIUrl":"https://doi.org/10.23880/oajmb-16000233","url":null,"abstract":"Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a severe and usually fatal syndrome with an aggressive thrombotic process in unusual sites (notably, sinus veins of the brain and/or splanchnic veins) that accompanies profound thrombocytopenia. If not well managed, VITT may progress to a more severe systemic disease such as disseminated intravascular coagulation. VITT was associated with two adenoviral vector vaccines, mainly ChAdOx1 nCoV-19 (AstraZeneca) and Ad26.COV2.S (Janssen/ Johnson & Johnson) was first reported in late February 2021 and mid-April 2021, respectively. This thrombotic phenomenon closely resembled that of autoimmune heparin-induced thrombocytopenia. Yet, in 2021, the MHRA (Medicines & Healthcare products Regulatory Agency) and the European Medicines Agency (EMA) claim no association between thrombosis and vaccines. Not long after, three scientific societies from Norway, Germany, and the UK reported in the press and social media the detection of thrombocytopenia with cerebral venous sinus thrombosis (CVST) and anti-platelet factor 4 (anti-PF4) antibodies in patients succeeding adenovirus-based vaccination. The immune response against PF4; (also known as CXCL4) in VITT is probably triggered by the proinflammatory milieu; compounds such as human cell-line proteins, non-assembled adenoviral proteins, and potentially EDTA (edetic acid) could be contributing to the prothrombotic state. This review will address functional aspects of PF4 in the thromboinflammatory phenomena, its role in the current anti-SARS-CoV-2 adenoviral-based vaccines, and evidence for its role in triggering VITT. Physicians as well as the public need to be aware of this new disease to quickly provide accurate diagnosis and timely treatment.","PeriodicalId":257510,"journal":{"name":"Open Access Journal of Microbiology & Biotechnology","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132566029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of Aqueous Two-Phase System to the Purification of Persimmon Polyphenol Oxidase 双水相系统在柿子多酚氧化酶纯化中的应用

Open Access Journal of Microbiology & Biotechnology Pub Date : 2022-07-04 DOI: 10.23880/oajmb-16000232

Kale E, Yuzugullu Karakus Y

引用次数: 0

Isolation and Characterization of Dermatophytes from Students Bathing Places 学生洗浴场所皮肤真菌的分离与鉴定

Open Access Journal of Microbiology & Biotechnology Pub Date : 2022-07-04 DOI: 10.23880/oajmb-16000235

Ebere Me

{"title":"Isolation and Characterization of Dermatophytes from Students Bathing Places","authors":"Ebere Me","doi":"10.23880/oajmb-16000235","DOIUrl":"https://doi.org/10.23880/oajmb-16000235","url":null,"abstract":"Background: Dermatophyte comprises of a vast range of filamentous pathogenic fungi that infect keratinous tissues of skin (the stratum corneum layer), hair, and nail in humans and animals via their keratinase enzymes which are capable of causing superficial infections. Aim: This study aimed to isolate and characterized dermatophytes isolated from students bathing places. Methodology: Four sampling sites were chosen from both male and female students bathing places; the floor, walls, sinks and door handles. Three hundred samples were collected and cultured on sterile plates containing Potato dextrose agar using spread plate method. The plates were incubated at 350C for 72 hours. Results: Out of three hundred samples collected from the various sampling sites, a total of four hundred and ten fungi were isolated, 286 (70%) were dermatophytes belonging to three genera (Trichophyton, Microsporum and Epidermorphyton) while124 (30%) were non dermatophytes. The female bathing places yielded 167(58%) and 48(39%) dermatophytes and Candida species respectively higher than male counterparts which yielded 119 (42%) dermatophytes without any species of Candida. There was no significant difference between the isolates from female and male bathrooms P ≥ 0.05. Conclusion: Hence the students bathing places were found to be rich in pathogenic and potentially pathogenic fungi and need thorough disinfectants to avoid dermatophytes infections’ like Tinea pedis, Tinea corporis Tinea capitis and Tinea cruris.","PeriodicalId":257510,"journal":{"name":"Open Access Journal of Microbiology & Biotechnology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132642059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Open Access Journal of Microbiology &amp; Biotechnology最新文献

Open Access Journal of Microbiology & Biotechnology最新文献