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International Journal of Pulmonary & Respiratory Sciences最新文献

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Idiopathic Pulmonary Fibrosis in A Young Patient with Strong Family Background 具有强烈家庭背景的年轻患者的特发性肺纤维化
International Journal of Pulmonary & Respiratory Sciences Pub Date : 2022-02-11 DOI: 10.19080/ijoprs.2022.05.555670
Ralph Nehme
{"title":"Idiopathic Pulmonary Fibrosis in A Young Patient with Strong Family Background","authors":"Ralph Nehme","doi":"10.19080/ijoprs.2022.05.555670","DOIUrl":"https://doi.org/10.19080/ijoprs.2022.05.555670","url":null,"abstract":"Background: Idiopathic pulmonary fibrosis (IPF) is the most common form of interstitial lung disease. It’s a chronic, progressive and often fatal disease. The etiology, pathophysiology and predisposing factors of IPF are still not fully understood. Genetic mutations leading to the disease are sometimes among the underlying predisposing factors leading to the entity known as familial pulmonary fibrosis (FPF). FPF is a rare entity and often overlooked. Not much data is available on the subject in the literature. For that reason, it’s important to increase awareness about this disease. Case presentation: In the following article, we report the case of a young patient presenting with a fibrosing lung disease that turns out being a familial pulmonary fibrosis. This case report goes over the challenges faced with the diagnosis, the approach for treatment and the genetic counseling in FPF. Conclusion: FPF is a rare disease with potential severe consequences for the patient. A high level of suspicions is required when making the diagnosis and potential genetic testing of family members might be required.","PeriodicalId":257243,"journal":{"name":"International Journal of Pulmonary & Respiratory Sciences","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126083988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intermittent Silent Coronary Spasm with Variant Premature Ventricular Contractions, and QRS-Complex Fragmentation in COVID-19 Pneumonia with Stroke and Pleural Effusion; Serious Risk but a Good Outcome 新型冠状病毒肺炎合并脑卒中和胸腔积液患者间歇性无症状冠状动脉痉挛伴变异性室性早搏及qrs复合碎片化风险很大，但结果很好
International Journal of Pulmonary & Respiratory Sciences Pub Date : 2022-01-24 DOI: 10.19080/ijoprs.2022.05.555669
Yasser Mohammed Hassanain Elsayed
{"title":"Intermittent Silent Coronary Spasm with Variant Premature Ventricular Contractions, and QRS-Complex Fragmentation in COVID-19 Pneumonia with Stroke and Pleural Effusion; Serious Risk but a Good Outcome","authors":"Yasser Mohammed Hassanain Elsayed","doi":"10.19080/ijoprs.2022.05.555669","DOIUrl":"https://doi.org/10.19080/ijoprs.2022.05.555669","url":null,"abstract":"Rationale : A pandemic COVID-19 virus is a multi-systemic lethal worldwide infection. Cardiac, neurological, chest, and renal systems are frequently involved. Silent coronary artery disease is sometimes reported in diabetic and elderly patients. There is a strong correlation between COVID-19 pneumonia, thromboembolism, and ischemic heart disease. Ischemic stroke and coronary artery disease are commonly clinically recognized in COVID-19 patients who have a risk impact on both morbidity and mortality. The QRS-complex fragmentation is considered as a marker for cardiac structural diseases inducing biventricular hypertrophy or any condition interfering with the normal homogeneous depolarization status inside the myocardium. Patient concerns: A 68-year-old, non-working, smoker, married, Egyptian male patient was admitted to the intensive care unit with cerebrovascular stroke, premature ventricular contractions, and COVID-19 pneumonia. Diagnosis: Intermittent silent coronary spasm with ischemic variant premature ventricular contractions, and QRS-complex fragmentation in COVID-19 pneumonia with stroke and pleural effusion. Interventions: Electrocardiography, oxygenation, non-contrast chest CT, and brain CT. Outcomes: Good response and better outcomes despite the presence of several remarkable risk factors were the results. Lessons: Intermittent silent coronary spasm is an interesting issue and maybe multi-factorial. The presence of elderly male sex, heavy smoker, COVID-19 pneumonia, pleural effusion, recurrent ischemic cerebrovascular stroke, renal impairment, ischemic heart disease, hypocalcemia, diabetes, ischemic variant premature ventricular contractions, and QRS-complex fragmentations are prognostic factors for the severity of the disease. The clinical and electrocardiographic response after using anti-COVID19 measures the signifying its role and suggests the diagnosis of COVID19 infection.","PeriodicalId":257243,"journal":{"name":"International Journal of Pulmonary & Respiratory Sciences","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121707013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Trapped Lung Cause by Chronic Pleural Effusion: Another Etiology of This Uncommon Disease 慢性胸腔积液致陷肺一例:此病的另一病因
International Journal of Pulmonary & Respiratory Sciences Pub Date : 2022-01-18 DOI: 10.19080/ijoprs.2022.05.555668
Hardik A. Fichadiya
{"title":"A Rare Case of Trapped Lung Cause by Chronic Pleural Effusion: Another Etiology of This Uncommon Disease","authors":"Hardik A. Fichadiya","doi":"10.19080/ijoprs.2022.05.555668","DOIUrl":"https://doi.org/10.19080/ijoprs.2022.05.555668","url":null,"abstract":"Trapped lung is defined by the inability of the lung to expand and fill the thoracic cavity. It is an outcome of fibrosis and thickening of visceral pleural preventing lung re-expansion. We present a 62 -year-old women with past medical history of chronic kidney disease and heart failure with preserved ejection fraction who presented with bilateral pleural effusions. Effusion on the right side was tapped draining a transudative fluid. Chest X ray on the following day showed a pneumothorax at the right lung base, the margins of which coincided which that of the effusion. The following day she now developed a hydro-pneumothorax in the same location. One rare yet reported cause of trapped lung is chronic pleural effusions in the setting of decompensated heart failure.","PeriodicalId":257243,"journal":{"name":"International Journal of Pulmonary & Respiratory Sciences","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133047179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bullous Lung Disease in Young IV Drug Abuser: A Case Report 青少年静脉吸毒致大疱性肺病1例报告
International Journal of Pulmonary & Respiratory Sciences Pub Date : 2021-12-15 DOI: 10.19080/ijoprs.2021.05.555667
Amanpreet Kaur
{"title":"Bullous Lung Disease in Young IV Drug Abuser: A Case Report","authors":"Amanpreet Kaur","doi":"10.19080/ijoprs.2021.05.555667","DOIUrl":"https://doi.org/10.19080/ijoprs.2021.05.555667","url":null,"abstract":"Drug abuse is defined as the non-medical “recreational” use of drugs that may result in physical or psychological dependence. Complications resulting from intravenous drug abuse affect the lung more frequently than any other organ. Drug abusers are also at risk from a wide range of pulmonary complications not directly related to infection. Non-infectious disorders may mimic more common pulmonary disease and may lead to respiratory insufficiency. Reports have documented evidence of emphysema with or without bullae formation in users of intravenous drugs. Most cases have been in drug abusers who inject medications intended for oral use and have occurred in association with intravenous talcosis. Bullous degeneration has been reported in intravenous opiate abuse presenting with pneumothorax or localized chest pain possibly due to air trapping. We encountered a unique case of bilateral upper lobe bullae in a young intravenous heroin abuser presented to us with right-sided hydropneumothorax.","PeriodicalId":257243,"journal":{"name":"International Journal of Pulmonary & Respiratory Sciences","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130184452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Specific Inhalation Challenge Test Results in Occupational and Non- Occupational Asthma Patients: Is Monitoring Peak Expiratory Flow Rate Sufficient for Diagnosis? 职业性和非职业性哮喘患者特异性吸入激发试验结果的比较:监测呼气峰流量是否足以诊断?
International Journal of Pulmonary & Respiratory Sciences Pub Date : 2021-11-19 DOI: 10.19080/ijoprs.2021.05.555666
Cebrail Şimşek, Bilge Akgunduz, Gulden Sari
{"title":"Comparison of Specific Inhalation Challenge Test Results in Occupational and Non- Occupational Asthma Patients: Is Monitoring Peak Expiratory Flow Rate Sufficient for Diagnosis?","authors":"Cebrail Şimşek, Bilge Akgunduz, Gulden Sari","doi":"10.19080/ijoprs.2021.05.555666","DOIUrl":"https://doi.org/10.19080/ijoprs.2021.05.555666","url":null,"abstract":"Objective: It is recommended to monitoring PEFR to diagnosing OA. Gold standard method is SIC test. The aim of this study is to evaluate comparison of SIC test results in patients with OA and non-OA and to discuss PEFR monitoring and underdiagnosed. Materials and Methods: 24 patients (16 OA, 8 non-OA) who underwent SIC test were analyzed retrospectively. Results: Although number of patients exposed to LMW (wood powders [n: 5]) was higher, IgE level was found significantly higher at OA (697.39 ± 839.36 kU/ml) (p: 0.027). Average PEFR monitoring days mean was 26.53±12.90.13 patients who diagnosed with OA with SIC was evaluated PEFR monitoring results were negative [%92.86]. Minimum FEV1 value on exposure day was lower in OA (p:0.001). Conclusion: We detected underdiagnosed cases rates were higher with diagnosing OA with PEFR monitoring alone. Our study also demonstrated that LMW agents cause immunological OA, independently from agent type and duration of exposure.","PeriodicalId":257243,"journal":{"name":"International Journal of Pulmonary & Respiratory Sciences","volume":"294 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121376034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of TSPO Ligand, Ro5-4864, on Lung Injury in ARDS Model Induced by ANTU in Rats TSPO配体Ro5-4864对ANTU所致ARDS模型大鼠肺损伤的影响
International Journal of Pulmonary & Respiratory Sciences Pub Date : 2021-10-28 DOI: 10.19080/ijoprs.2021.05.555665
Emine Yilmaz-Can
{"title":"Effect of TSPO Ligand, Ro5-4864, on Lung Injury in ARDS Model Induced by ANTU in Rats","authors":"Emine Yilmaz-Can","doi":"10.19080/ijoprs.2021.05.555665","DOIUrl":"https://doi.org/10.19080/ijoprs.2021.05.555665","url":null,"abstract":"","PeriodicalId":257243,"journal":{"name":"International Journal of Pulmonary & Respiratory Sciences","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124889248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Activated Macrophage and Granulomatous Inflammation 活化巨噬细胞与肉芽肿性炎症
International Journal of Pulmonary & Respiratory Sciences Pub Date : 2021-10-23 DOI: 10.19080/ijoprs.2021.05.555664
Mehwish Azhar
{"title":"Activated Macrophage and Granulomatous Inflammation","authors":"Mehwish Azhar","doi":"10.19080/ijoprs.2021.05.555664","DOIUrl":"https://doi.org/10.19080/ijoprs.2021.05.555664","url":null,"abstract":"The granulomatous inflammation is a characteristic type of chronic inflammation in which main cells are macrophages, multinucleated cells and epithelioid cells. The dynamic structure of granuloma helps to defend the body from microbiological threats. Granulomatous inflammation is a histologic pattern of tissue reactions which appears following cell damage. A variety of systemic diseases are occurred by this special inflammatory response. The granulomatous inflammatory response is common in many infective, allergic, autoimmune, toxic and neoplastic diseases. Mechanism that regulates granulomatous inflammation is remain not properly understood. The pulmonary system is one of the most common concerned sites to face the granulomatous inflammation. Unlike the lungs, skin can be affected by different ways including direct inoculation, endogenous origins and hematogenous spread. In this theory, we discuss about formation of granuloma, and that the granulomatous inflammation is a protective mechanism of our body but sometimes it can also cause serious and severe diseases in different body organs.","PeriodicalId":257243,"journal":{"name":"International Journal of Pulmonary & Respiratory Sciences","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134522978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of Biologic Drugs for Treatment of Allergic Bronchopulmonary Aspergillosis 生物药物治疗过敏性支气管肺曲菌病的应用
International Journal of Pulmonary & Respiratory Sciences Pub Date : 2021-10-11 DOI: 10.19080/ijoprs.2021.05.555663
S. Albogami
{"title":"Use of Biologic Drugs for Treatment of Allergic Bronchopulmonary Aspergillosis","authors":"S. Albogami","doi":"10.19080/ijoprs.2021.05.555663","DOIUrl":"https://doi.org/10.19080/ijoprs.2021.05.555663","url":null,"abstract":"Allergic bronchopulmonary aspergillosis (ABPA) is an allergic fungal infection that induces immunoglobulin E (IgE) production and eosinophils proliferation and affect mostly asthmatic and cystic fibrosis patients. The mainstay treatment for ABPA is systemic steroid and antifungal treatment which have increasing rates of treatment failure and side effects. Because of their mechanism of action in suppressing IgE or eosinophils, biologic drugs were expected to play an important role in the treatment of ABPA, however, their use in this issue was off label and lack the evidence. In this comprehensive and comparative review, 59 full text articles (228 patients) were selected. The outcomes were analyzed and the percentages of posttreatment change for each variable in each study were collected then the overall median percentages were calculated for each variable for each biologic drug. Comparative discussion of these outcomes was done in terms of clinical and functional response, reduction of exacerbation events, reduction of IgE level and eosinophils count, prevention of complications and patient’s ability to reduce steroid dose or discontinue it. The review shows that the use of biologic drugs for treatment of ABPA is associated with a significant clinical and functional improvement and reduction of exacerbation rates up to 90%. There is more reduction in post-treatment IgE level with mepolizumab and marked reduction in posttreatment eosinophils count with benralizumab. Mepolizumab has the better steroid-sparing effect. Changing from one biologic drug to another with different target in case of treatment failure is advisable. More stronger studies and randomized control trials are needed to figure out the use of biologic drugs for ABPA treatment.","PeriodicalId":257243,"journal":{"name":"International Journal of Pulmonary & Respiratory Sciences","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132924302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
The Effects of Cannabinoid System on Acute Lung Injury Induced by Mesenteric Ischemia/Reperfusion in Rats 大麻素系统对大鼠肠系膜缺血再灌注急性肺损伤的影响
International Journal of Pulmonary & Respiratory Sciences Pub Date : 2021-09-30 DOI: 10.19080/ijoprs.2021.05.555662
Emine Yilmaz-Can
{"title":"The Effects of Cannabinoid System on Acute Lung Injury Induced by Mesenteric Ischemia/Reperfusion in Rats","authors":"Emine Yilmaz-Can","doi":"10.19080/ijoprs.2021.05.555662","DOIUrl":"https://doi.org/10.19080/ijoprs.2021.05.555662","url":null,"abstract":"","PeriodicalId":257243,"journal":{"name":"International Journal of Pulmonary & Respiratory Sciences","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127480549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Avoiding Aortic Injury During Thoracentesis: A Case Report with An Emphasis on Ultrasound Guidance 胸穿刺时避免主动脉损伤:以超声引导为主的一例报告
International Journal of Pulmonary & Respiratory Sciences Pub Date : 2021-09-23 DOI: 10.19080/ijoprs.2021.05.555661
Sultan R. Alharbi
{"title":"Avoiding Aortic Injury During Thoracentesis: A Case Report with An Emphasis on Ultrasound Guidance","authors":"Sultan R. Alharbi","doi":"10.19080/ijoprs.2021.05.555661","DOIUrl":"https://doi.org/10.19080/ijoprs.2021.05.555661","url":null,"abstract":"Percutaneous pigtail catheter thoracentesis is a common and relatively safe procedure for pleural drainage, often performed with ultrasound guidance. While injury to an intrathoracic organ is a rare and sometimes fatal complication of this procedure, ultrasound is an excellent tool for avoiding this complication and for evaluating pleural effusion. In this case report, the use of ultrasound imaging with various techniques and planes prior to and during thoracentesis is described for the identification of the thoracic aorta and for avoidance of fatal aortic injury.","PeriodicalId":257243,"journal":{"name":"International Journal of Pulmonary & Respiratory Sciences","volume":"8 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120999757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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