Biomaterials and Biosensors最新文献

A comprehensive review on biogenically synthesized inorganic nanoparticles and their applications in anticancer activities 生物合成无机纳米粒子及其在抗癌活动中的应用综述

Biomaterials and Biosensors Pub Date : 2023-08-16 DOI: 10.58567/bab02010004

Zahra Barreto, Areej Fatima, Tuba Tariq, A. Zafar, M. S. Saif, Amina Zafar, Areeba Yousaf, Huang Xue, M. Hasan

{"title":"A comprehensive review on biogenically synthesized inorganic nanoparticles and their applications in anticancer activities","authors":"Zahra Barreto, Areej Fatima, Tuba Tariq, A. Zafar, M. S. Saif, Amina Zafar, Areeba Yousaf, Huang Xue, M. Hasan","doi":"10.58567/bab02010004","DOIUrl":"https://doi.org/10.58567/bab02010004","url":null,"abstract":"The progression in nanotechnology has revolutionized the biomedical sciences for diagnosis and treatment of diseases like cancer. There have been many kinds of nanomaterials but Inorganic nanomaterials have been considered potential candidates for anticancer activities due to their high biocompatibility, less toxicity, high stability, and high precision in targeting affected cells. Several synthesis approaches have been used to prepared these nanoparticles, such as physical, chemical, and biogenic methods. Due to higher toxicity and adverse effects of chemical methods, eco-friendly way such as biosynthesized inorganic nanomaterials have attained much attention for multiple application particularly treatment of diseases. This review presents a comprehensive and updated knowledge (2015-2023) regarding the cancer treatment. The article first categorizes biogenically synthesized inorganic nanoparticles into three main groups: metallic nanoparticles, metal oxide nanoparticles, and quantum dots and then successful stories related to cancer treatment. This will also provide very effective platform for researchers and academia to detail the biogenically synthesized inorganic nanoparticles’ morphology, their characterization, targeted cancer cells.","PeriodicalId":257097,"journal":{"name":"Biomaterials and Biosensors","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139350359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of nanodrugs in the treatment of cardiovascular diseases 纳米药物在心血管疾病治疗中的应用

Biomaterials and Biosensors Pub Date : 2023-07-17 DOI: 10.58567/bab02010003

Qiang Xie, Hongmei Yang, Wenjie Shi

{"title":"Application of nanodrugs in the treatment of cardiovascular diseases","authors":"Qiang Xie, Hongmei Yang, Wenjie Shi","doi":"10.58567/bab02010003","DOIUrl":"https://doi.org/10.58567/bab02010003","url":null,"abstract":"Cardiovascular disease is still a disease with high incidence rate and mortality. Although advanced technology continues to increase our understanding of cardiovascular disease, its diagnosis and treatment still have limitations. As an emerging interdisciplinary method, nanotechnology has shown enormous clinical application potential. Nanomaterials have unique physical and chemical properties, which help to improve the sensitivity and specificity of biosensor technology and molecular imaging technology in the diagnosis of cardiovascular diseases. This paper first summarizes the versatility of nanomaterials, the physicochemical adjustability of biomolecular engineering, the design strategy of nanoparticles in cardio cerebral Vascular disease, the application of nanomaterials in the diagnosis and treatment of common cardiovascular diseases, and the use of nanomaterials can significantly improve the diagnostic sensitivity, specificity and therapeutic effect. Subsequently, the article summarized various nanomaterials. Finally, the article demonstrated the potential of the antioxidant/anti-inflammatory and photoelectric/photothermal properties of nanomaterials to be directly applied to the treatment of cardiovascular diseases.","PeriodicalId":257097,"journal":{"name":"Biomaterials and Biosensors","volume":"40 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130214343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Overcoming the challenge: cell-penetrating peptides and membrane permeability 克服挑战:细胞穿透肽和膜渗透性

Biomaterials and Biosensors Pub Date : 2023-06-29 DOI: 10.58567/bab02010002

Yuan Gu, Long Wu, Y. Hameed, M. Nabi-Afjadi

引用次数: 1

Advances in Novel Tumor Therapeutics Based on Nanomaterial Technologies 基于纳米材料技术的新型肿瘤治疗方法研究进展

Biomaterials and Biosensors Pub Date : 2023-05-23 DOI: 10.58567/bab02010001

Chen Li, Yi Liu

引用次数: 1

An DNA Enzyme Electrochemiluminescence Biosensor for Ultra-sensitive Detection of Pb2+ Based on CdS/MoS2 Joint Amplification 基于CdS/MoS2联合扩增的Pb2+超灵敏DNA酶电化学发光生物传感器

Biomaterials and Biosensors Pub Date : 2022-12-30 DOI: 10.58567/bab01010003

Rui Yang

引用次数: 0

Development of an Electrochemical Aptasensor for Ultrasensitive Detection of Tetracycline in Eggs 鸡蛋中四环素超灵敏检测电化学配体传感器的研制

Biomaterials and Biosensors Pub Date : 2022-12-30 DOI: 10.58567/bab01010002

Jianqi Li, Xin Jin

{"title":"Development of an Electrochemical Aptasensor for Ultrasensitive Detection of Tetracycline in Eggs","authors":"Jianqi Li, Xin Jin","doi":"10.58567/bab01010002","DOIUrl":"https://doi.org/10.58567/bab01010002","url":null,"abstract":"In recent years, in order to prevent the occurrence of various diseases, the fncscrambled misuse of antibiotics is quite serious, and the residues of antibiotics such as tetracycline in eggs can also cause damage to human health. A double-stranded DNA probe modified with ferrocene was immobilized onto a gold nanoparticle modified substrate. Tetracycline was added to form a strong affinity binding between the target and the aptamer. During this process, the complementary strand was detached from the electrode surface. Therefore, the measured electrical signal attenuates with the emergence of the target. The linear response of tetracycline concentration to the signal ranged from 0.0005μM~50μM. The fabricated biosensor showed excellent selectivity. The accurate detection limit can be as low as 0.5 nm. Further, in the determination of tetracycline concentrations in water and egg samples, the fabricated biosensor showed excellent selectivity. Furthermore, the applicability of the developed sensor was demonstrated in the determination of tetracycline concentrations in egg samples. The spiking recoveries ranged from 96.18% to 102.75% which reached acceptable level. This detection sensor is simple, time-saving, selective and efficient, which can provide potential services in food production safety, environmental detection and so on.","PeriodicalId":257097,"journal":{"name":"Biomaterials and Biosensors","volume":"101 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117291742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Noninvasive Deep-Tissue Temperature Monitoring Based on Magnetic Mediated Thermoacoustics 基于磁介导热声学的无创深部组织温度监测

Biomaterials and Biosensors Pub Date : 2022-12-30 DOI: 10.58567/bab01010005

Siyu Liu

引用次数: 0

Detection of 16 kDa Protein from Mycobacterium Tuberculosis Using Interdigitated Electrode 交叉指状电极检测结核分枝杆菌16kda蛋白

Biomaterials and Biosensors Pub Date : 2022-12-30 DOI: 10.58567/bab01010001

S. S. Rani, S. Gopinath

引用次数: 0

Polymers containing natural plant phenolic compounds for peripheral nerve injury 含有天然植物酚类化合物的聚合物用于周围神经损伤

Biomaterials and Biosensors Pub Date : 2022-12-30 DOI: 10.58567/bab01010004

Tongyan Zheng, Shuoke Qiu, Lei Li, Binglong Li, Meng Zhang

{"title":"Polymers containing natural plant phenolic compounds for peripheral nerve injury","authors":"Tongyan Zheng, Shuoke Qiu, Lei Li, Binglong Li, Meng Zhang","doi":"10.58567/bab01010004","DOIUrl":"https://doi.org/10.58567/bab01010004","url":null,"abstract":"Peripheral nerve injury is a serious and disabling disease prevalent in the world. It caused by trauma is often accompanied with soft tissue injuries, fractures, infections, etc., and can cause permanent damage. The treatment methods of peripheral nerve injury mainly include traditional microsurgical repair, neurotrophic drug treatment, as well as cuttingedge nerve conduit treatment, nerve stimulation, cell therapy, etc. However, more than 30% of patients with peripheral nerve injury still have poor recovery, including partial loss or complete loss of motor and/or sensory function, muscle atrophy，chronic pain and severe disability, among can lead to permanent disease. Phenolic compounds are secondary metabolites which is the most abundant in plants, consisting of an aromatic ring and one or more hydroxyl substituents, the main groups including flavonoids, phenolic acids, tannins, stilbene and lignans. A lot of studies have shown that natural phenolic compounds have various properties, such as antioxidant, anti-infective, anticancer, anti-inflammatory, etc., and have broad applications in the prevention of heart disease, cancer, diabetes, oxidative stress-related diseases, and neuroprotection prospect. This review discusses the potential applications and molecular mechanisms of natural phenolic compounds its polymer derivatives in the treatment of peripheral nerve injury.","PeriodicalId":257097,"journal":{"name":"Biomaterials and Biosensors","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129746836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0