Global Journal of Biotechnology and Biomaterial Science最新文献

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New developments in medicine through artificial intelligence and advances in biotechnology – an overview 通过人工智能和生物技术的进步实现医学的新发展--综述
Global Journal of Biotechnology and Biomaterial Science Pub Date : 2024-02-16 DOI: 10.17352/gjbbs.000020
Manfred Doepp
{"title":"New developments in medicine through artificial intelligence and advances in biotechnology – an overview","authors":"Manfred Doepp","doi":"10.17352/gjbbs.000020","DOIUrl":"https://doi.org/10.17352/gjbbs.000020","url":null,"abstract":"Medicine has changed rarely in history as rapidly as it is today. Constantly new methods are being introduced that can improve health outcomes. Six such developments are presented in this article, that is, Artificial Intelligence (AI) in diagnosis and treatment, 3D-printed organs, tele-surgery, nano-medicine, CRISPR technology, and quantum teleportation. Thus, with these developments, several problems in medicine can be solved to the benefit of patients. However, it also increases the responsibility of users to apply the methods in accordance with ethical principles.","PeriodicalId":256812,"journal":{"name":"Global Journal of Biotechnology and Biomaterial Science","volume":"305 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140454342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomedical evaluation of green tea herbal liquid with bama miniature pigs 绿茶草药液对巴马小型猪的生物医学评价
Global Journal of Biotechnology and Biomaterial Science Pub Date : 2023-06-10 DOI: 10.17352/gjbbs.000019
Liang Yufan, Zhao Xinggang, L. Jun, Lin Mingyue, Wang Chenxin, Zhang Rui, Chen Li, Zou Qin
{"title":"Biomedical evaluation of green tea herbal liquid with bama miniature pigs","authors":"Liang Yufan, Zhao Xinggang, L. Jun, Lin Mingyue, Wang Chenxin, Zhang Rui, Chen Li, Zou Qin","doi":"10.17352/gjbbs.000019","DOIUrl":"https://doi.org/10.17352/gjbbs.000019","url":null,"abstract":"Traditional Chinese Medicine (TCM) is widely used in health preservation and non-radical treatment because of its relatively gentle therapeutic effect, which is reflected in many products. Especially in atomization therapy, TCM shows its strong potential. This experiment focused on analyzing the extract of green tea (tea polyphenols) in a nebulizer, which is very similar to e-cigarettes. After intravenous injection of relevant drugs into small experimental pigs, the results of blood tests and the HE staining of organ sections showed no abnormalities in the experimental group. Since the dose of intravenous injection is much larger than that of nebulized inhalation, the safety of the product was verified by the experiment. The relevant analysis results obtained in this experiment will be used for comparison with subsequent, longer-term (more than 3 months) injection experiments.","PeriodicalId":256812,"journal":{"name":"Global Journal of Biotechnology and Biomaterial Science","volume":"164 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123903606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biological toxicity evaluation of traditional medicine white tea extract liquid 中药白茶提取液的生物毒性评价
Global Journal of Biotechnology and Biomaterial Science Pub Date : 2023-03-16 DOI: 10.17352/gjbbs.000018
Z. Rui, Lin Mingyue, Wang Chenxin, Liang Yufan, Zhao Xinggang, L. Jun, Chen Li, Zou Qin
{"title":"Biological toxicity evaluation of traditional medicine white tea extract liquid","authors":"Z. Rui, Lin Mingyue, Wang Chenxin, Liang Yufan, Zhao Xinggang, L. Jun, Chen Li, Zou Qin","doi":"10.17352/gjbbs.000018","DOIUrl":"https://doi.org/10.17352/gjbbs.000018","url":null,"abstract":"Purpose: The aim of this study was to evaluate the safety and toxicity of intravenous use of White Tea Extract Liquid (WT) in rabbits through routine blood tests and biochemical and histopathological means. Design and methods: This study used the WT product produced by the company and the New Zealand rabbits at 2.0~2.5 kg of weight. Rabbits were divided into two groups: Control and WT groups. In the WT group, the diluted WT injection volume needed to be injected was calculated according to their body weight on days 1, 4, 7 and 11...... for 4 weeks respectively. During the1, 2 and 4 weeks of the experiment, blood routine, blood biochemistry and the histopathological sections of the heart, spleen, lung, trachea, kidney, bladder, uterus, testicle, stomach, liver, small intestine, big intestine were evaluated in the study. Findings: By comparison, the blood routine test did not deviate from the normal ranges provided by the diagnostic laboratory. The blood biochemical indexes of all experimental rabbits are within a reasonable range and did not detect clinically significant abnormalities between treatment and control groups. The WT had no obvious inflammatory change in the whole tissue and no harmful effect on the organs of various systems of the rabbits’ system for 4 weeks. Conclusions: After intravenous injection for 4 weeks in rabbits, white tea herb atomization liquid did not produce obvious toxic effects on the animals.","PeriodicalId":256812,"journal":{"name":"Global Journal of Biotechnology and Biomaterial Science","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132539186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experimental investigation of gamma stirling engine coupling to convert thermal to cooling energy in different laboratory conditions 不同实验室条件下将热能转化为冷能的伽马斯特林发动机耦合实验研究
Global Journal of Biotechnology and Biomaterial Science Pub Date : 2022-06-14 DOI: 10.17352/gjbbs.000017
Daneshgar Sareh, Zahedi Rahim, Asemi Hamidreza
{"title":"Experimental investigation of gamma stirling engine coupling to convert thermal to cooling energy in different laboratory conditions","authors":"Daneshgar Sareh, Zahedi Rahim, Asemi Hamidreza","doi":"10.17352/gjbbs.000017","DOIUrl":"https://doi.org/10.17352/gjbbs.000017","url":null,"abstract":"The main aim of this research is to experimentally investigate the two coupled identical ST500 gamma-type Stirling engines and convert thermal energy to cooling energy. Using a new structure and two coupled Stirling engines at different temperatures and pressures and the use of biomass fuel within the 4 -8 bar average pressure range of the first engine heat source, the 1-4 bar average pressure range of the second engine heat sink, and Stirling heat engine temperature range of 480-580 ºC, the effective cooling is obtained in the cooling engine. In doing tests, attempts were made to reach lower than 9 percent error results in different parts of the engine, including insulation, fluid leakage, belt loss, and measurement devices. According to the obtained results, 8 bars increase in the average pressure range of the gas in the first engine heat source, a 1 bar reduction in the average pressure range of the gas in the second engine heat sink, the increased temperature of the heat source up to 580ºC, and the use of the light operating fluid such as helium will affect the generation of cooling up to-16ºC.","PeriodicalId":256812,"journal":{"name":"Global Journal of Biotechnology and Biomaterial Science","volume":"142 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133824539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Treatment of diabetic muscular hyperplasia with natural and nutritional supplements 用天然和营养补充剂治疗糖尿病性肌肉增生
Global Journal of Biotechnology and Biomaterial Science Pub Date : 2022-05-25 DOI: 10.17352/gjbbs.000016
Khan Safir Ullah, Khan Munir Ullah
{"title":"Treatment of diabetic muscular hyperplasia with natural and nutritional supplements","authors":"Khan Safir Ullah, Khan Munir Ullah","doi":"10.17352/gjbbs.000016","DOIUrl":"https://doi.org/10.17352/gjbbs.000016","url":null,"abstract":"Skeletal muscle is an important part of the human body. Most glucose metabolism is accomplished by skeletal muscle through insulin mediation. Skeletal muscle metabolism disorder can affect glucose metabolic homeostasis and insulin sensitivity of the body, and diabetic muscular Hypoplasia is a secondary lesion of muscle tissue caused by diabetes. In recent years, it has been found that in addition to mainstream western medicine and traditional Chinese and Western medicine combined treatment programs, natural products, and nutritional supplements also play an important role in the prevention and treatment of diabetic muscular Hypoplasia. Therefore, this paper will discuss the definition and pathogenesis of diabetic muscular Hypoplasia, as well as the prevention and treatment mechanism of some natural products and nutritional supplements, to provide more theoretical reference for non-drug targeted therapy of diabetic muscular Hypoplasia.","PeriodicalId":256812,"journal":{"name":"Global Journal of Biotechnology and Biomaterial Science","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114071133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Key Factors for Successful Protein Purification and Crystallization 成功的蛋白质纯化和结晶的关键因素
Global Journal of Biotechnology and Biomaterial Science Pub Date : 2018-08-10 DOI: 10.17352/gjbbs.000010
E. Bhat, Mohnad Abdalla, I. Rather
{"title":"Key Factors for Successful Protein Purification and Crystallization","authors":"E. Bhat, Mohnad Abdalla, I. Rather","doi":"10.17352/gjbbs.000010","DOIUrl":"https://doi.org/10.17352/gjbbs.000010","url":null,"abstract":"Protein purification and crystallization problems have been noticed for many years. The strategies developed for protein solubility and crystallization have improved the protein production and provide high-resolution crystals for structural studies. The protein solubility is achieved by the Site-directed mutagenesis that generates the hydrophobic to hydrophilic mutations. However, the purity and rate of crystallization success still needs to be improved.","PeriodicalId":256812,"journal":{"name":"Global Journal of Biotechnology and Biomaterial Science","volume":"176 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134088131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
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