TP55. TP055 MECHANICAL VENTILATION, ICU MANAGEMENT, AND CV最新文献

{"title":"Differential Expression of Skeletal Muscle Regulators in Critically Ill Patients","authors":"S. Jolley, J. Gaydos, C. Higgins, J. Mckeehan, M. Moss, E. Burnham","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2832","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2832","url":null,"abstract":"","PeriodicalId":255004,"journal":{"name":"TP55. TP055 MECHANICAL VENTILATION, ICU MANAGEMENT, AND CV","volume":"244 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133788208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association Between Elevated Temperature in the First 72 Hours and Neurologic Outcome Among Patients Who Received Therapeutic Hypothermia After Out-of-Hospital Cardiac Arrest","authors":"A. Schick, D. Evans, J. Hall, A. Caraganis, R. Kempainen, M. Prekker","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2842","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2842","url":null,"abstract":"","PeriodicalId":255004,"journal":{"name":"TP55. TP055 MECHANICAL VENTILATION, ICU MANAGEMENT, AND CV","volume":"34 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133052626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Immunoglobulin G (IgG) Against N-protein of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) in Coronavirus Disease 2019 (COVID19) Clinical Outcomes","authors":"S. Haddadi, L. Escudero Méndez, M. Batra, T. Runxia, C. Zhang, C. Emile, C. Sacher, J. Miranda, J. R. O. De La Fuente, M. Mathew, D. Green, S. Patel, M. V. Perez Bastidas, M. Murthi, M. S. Gonzalez-Mancera, S. Kambali, K. Santos, H. Asif, F. Modarresi, M. Faghihi, M. Mirsaeidi","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2822","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2822","url":null,"abstract":"RATIONALE: The Nucleocapsid Protein (N Protein) of severe acute respiratory syndrome Coronavirus 2 (SARSCoV2) is located in the viral core. Immunoglobulin G (IgG) targeting N protein is detectable in the serum of infected patients. The effect of high titers of IgG against N-protein on clinical outcomes of SARS-CoV2 disease has not been described. METHODS: We studied 400 RT-PCR confirmed SARS-CoV2 patients to determine independent factors associated with poor outcomes, including MICU admission, prolonged MICU stay, and hospital admissions, and in-hospital mortality. We also measured serum IgG against the N protein and correlated its concentrations with clinical outcomes. RESULTS: We found that several factors, including Charlson comorbidity Index (CCI), high levels of IL6, and presentation with dyspnea were associated with poor clinical outcomes. It was shown that higher CCI and higher IL6 levels were independently associated with in-hospital mortality. Anti-N protein IgG was detected in the serum of 55 (55%) patients at the time of admission. A high concentration of antibodies, defined as signal to cut off ratio (S/Co)> 1.5 (75 percentile of all measurements), was found in 25 (25%) patients. The multivariable logistic regression models showed that between being an African American, higher CCI, lymphocyte counts, and S/Co ratio> 1.5, only S/Co ratio were independently associated with MICU admission and longer length of stay in hospital. (Figure 1) CONCLUSION: This study recommends that titers of IgG targeting N-protein of SARS-CoV2 at admission is a prognostic factor for the clinical course of disease and should be measured in all patients with SARS-CoV2 infection.","PeriodicalId":255004,"journal":{"name":"TP55. TP055 MECHANICAL VENTILATION, ICU MANAGEMENT, AND CV","volume":"70 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134259392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Implementation and Longitudinal Evaluation Framework of Remote Quality Improvement Initiatives","authors":"H. Li, Y. Sun, Yue Dong, A. Tekin, R. Kashyap, W. Cui, A. Leppin, O. Gajic, A. Niven","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2851","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2851","url":null,"abstract":"Objective: Virtual learning experiences have become widely used during the ongoing COVID-19 global crisis. Given its cost-effectiveness, accessibility, and flexibility, remote training experiences are likely to assume a permanent and expanded role in medical education and quality improvement initiatives. However, little is known about how best to measure the effectiveness of remote training interventions. The Checklist for Early Recognition and Treatment of Acute Illness and Injury (CERTAIN) is an established critical care quality improvement program with evidence of improved care processes and patient outcomes in an international quality improvement trial. Our aim was to develop a structured implementation and longitudinal evaluation framework that measures the complex contributors to the impact of this remote training program, including incorporation into processes of care and sustainment over time. Methods: We convened an international topic review group that included individuals with diversity in clinical expertise, nationality, and experience in medical education, quality improvement, implementation science, and research methodology. We recruited individuals with experience designing and participating in various medical remote training programs, including teleconferences, tele-consults, online video/chat platforms, and virtual simulation classrooms. Through a series of facilitated discussions, we directed the group to develop a conceptual framework to guide the development of remote learning programs and accompanying evaluation tools to measure their impact. Results: The review group members included education experts and continuing medical education participants from China and the United States with practice backgrounds in Critical Care, Internal Medicine, Anesthesiology and Emergency Medicine. The group developed a conceptual framework based on the CIPP (context-input-process-product) quality evaluation model. The framework includes three phases: before, during, and after the remote training. The proposed quantitative and qualitative evaluation tools blend the Proctor taxonomy, an expansion of the popular RE-AIM framework used to categorize implementation outcomes, to include early (i.e. acceptability, appropriateness, feasibility), mid (i.e. adoptions, fidelity), and late (i.e. sustainability) stage outcomes to provide a more complete understanding of the implementation process and facilitate generalization of our findings. Elements of the Logic Model were also used to guide the program development process. Conclusions: We propose a dynamic, longitudinal implementation evaluation framework that has sufficient rigor and flexibility to meet the needs of the existing and emerging remote medical training programs in global practice settings. The outcomes from these mixed-methods analyses will provide a robust toolbox to guide the design, delivery, implementation, and sustainment of remote medical educational programs.","PeriodicalId":255004,"journal":{"name":"TP55. TP055 MECHANICAL VENTILATION, ICU MANAGEMENT, AND CV","volume":"193 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133242454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Combined Effect of Intraoperative Transfusion and Cardiopulmonary Bypass Use/Durationon Postoperative Pulmonary Complications and Mortalityat Short, Intermediate and Long Term Follow Up","authors":"S. Badour, J. Abi Jaoude, T. Schwann","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2846","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2846","url":null,"abstract":"","PeriodicalId":255004,"journal":{"name":"TP55. TP055 MECHANICAL VENTILATION, ICU MANAGEMENT, AND CV","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123673097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Multi-Professional Mobilization on Physical Function, Clinical and Quality Indicators of Intensive Care Delivery in a Low-Resource Setting: An Action on \"Rehabilitation 2030\" in Brazil","authors":"R. Mendes, Tmpc Biazon, H. Pott-Junior, F.C.R. Caruso-Bonjorno, J. C. Bonjorno-Junior, M. Lazzarini, M. Taconelli, A.B. Silva","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2825","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2825","url":null,"abstract":"","PeriodicalId":255004,"journal":{"name":"TP55. TP055 MECHANICAL VENTILATION, ICU MANAGEMENT, AND CV","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123857950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Artificial Airway Choice on Aerosol Drug Delivery During Simulated Adult Mechanical Ventilation","authors":"J. Robertson, B. Murphy, A. O'Sullivan, M. Mac Giolla Eain, M. Joyce, R. Macloughlin","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2805","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2805","url":null,"abstract":"","PeriodicalId":255004,"journal":{"name":"TP55. TP055 MECHANICAL VENTILATION, ICU MANAGEMENT, AND CV","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128998663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilization of Multidisciplinary Rounding in the ICU to Decrease CAUTI","authors":"K. Galang, M. Bogonot, E. Cardona, A. Afshar, G. P. Singh","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2823","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2823","url":null,"abstract":"","PeriodicalId":255004,"journal":{"name":"TP55. TP055 MECHANICAL VENTILATION, ICU MANAGEMENT, AND CV","volume":"167 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122976720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vasoactive Drug and Autonomic Control of Cardiac Activity in Response to Early Mobilization in Patients with Septic Shock","authors":"R. Mendes, D. Kawakami, M.J.C. Melger, N. M. Garcia, T. Destro, Tmpc Biazon, F.C.R. Caruso-Bonjorno, J. C. Bonjorno-Junior, A.B. Silva","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2837","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2837","url":null,"abstract":"","PeriodicalId":255004,"journal":{"name":"TP55. TP055 MECHANICAL VENTILATION, ICU MANAGEMENT, AND CV","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123719627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Breathing Efforts Affected by Positive End-Expiratory Pressure in Acute Respiratory Distress Syndrome","authors":"D. Bouhassira, M. Schaefer, V. Banner-Goodspeed, D. Talmor, J. Beitler, E. Baedorf Kassis","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2809","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2809","url":null,"abstract":"","PeriodicalId":255004,"journal":{"name":"TP55. TP055 MECHANICAL VENTILATION, ICU MANAGEMENT, AND CV","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126467946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}