Sokoto Journal of Veterinary Sciences最新文献

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Cystic endometrial hyperplasia-pyometra complex in a mastectomized Boerboel bitch following tamoxifen administration 他莫昔芬给药后乳房切除的Boerboel母狗的囊性子宫内膜增生-子宫脓肿复肿
Sokoto Journal of Veterinary Sciences Pub Date : 2021-11-04 DOI: 10.4314/sokjvs.v19i3.11
T. Ajadi, E. Okpara, A. O. Alamu, L. Mustapha, I. O. Oyenekan, M. O. Ilugbo
{"title":"Cystic endometrial hyperplasia-pyometra complex in a mastectomized Boerboel bitch following tamoxifen administration","authors":"T. Ajadi, E. Okpara, A. O. Alamu, L. Mustapha, I. O. Oyenekan, M. O. Ilugbo","doi":"10.4314/sokjvs.v19i3.11","DOIUrl":"https://doi.org/10.4314/sokjvs.v19i3.11","url":null,"abstract":"\u0000 \u0000 \u0000 \u0000Tamoxifen is a non-steroidal, anti-estrogenic and selective estrogen receptor modulator commonly used as adjuvant chemotherapy in humans with breast cancer and occasionally in dogs following mastectomy. This report presents a case of cystic endometrial hyperplasia-pyometra in a dog following oral administration of the tamoxifen. A 4-year-old intact nulliparous Boerboel bitch presented at Veterinary Teaching Hospital, Federal University of Agriculture, Abeokuta. It was diagnosed with mammary carcinoma of the right cranial lumbar mammary gland. Mastectomy was performed followed by oral administration of Tamoxifen (10mg daily) for six weeks as adjunct chemotherapy. Eight weeks after, the owner reported that the bitch was lethargic, anorexic and had a purulent vaginal discharge. Abdominal ultrasound revealed cystic endometrial hyperplasia. Results of complete blood counts showed neutrophilic (absolute neutrophil count = 19.5×103/L) leukocytosis (total leukocyte count = 24.9X103/L), while bacterial culture yielded moderate growth of Staphylococcus aureus, which was sensitive to Ciprofloxacin, Ofloxacin, Sparfloxacin and Gentamycin. The bitch was treated with 400μg of Misoprostol and 500mg of Ciprofloxacin twice daily for two weeks. Ovariohysterectomy (OVH) was performed using a ventral midline approach when no significant improvement was observed from medical treatment. The dog improved significantly after ovariohysterectomy and was discharged one week after OVH. It was concluded that, although tamoxifen is routinely used as adjuvant chemotherapy following mastectomy, more research is required to evaluate its safety in intact bitches. \u0000 \u0000 \u0000 \u0000","PeriodicalId":253894,"journal":{"name":"Sokoto Journal of Veterinary Sciences","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116930460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Six decades of infectious bursal disease in poultry: The journey so far and challenges ahead 家禽传染性法氏囊病的六十年:迄今为止的旅程和未来的挑战
Sokoto Journal of Veterinary Sciences Pub Date : 2021-11-04 DOI: 10.4314/sokjvs.v19i3.1
N. Lawal, M. Bello
{"title":"Six decades of infectious bursal disease in poultry: The journey so far and challenges ahead","authors":"N. Lawal, M. Bello","doi":"10.4314/sokjvs.v19i3.1","DOIUrl":"https://doi.org/10.4314/sokjvs.v19i3.1","url":null,"abstract":"\u0000 \u0000 \u0000Despite six decades of concerted efforts, Infectious bursal disease (IBD) still remains a major threat to the poultry industry worldwide. Most importantly, the emergence of variant and very virulent strains of infectious bursal disease virus (IBDV) has dramatically changed the epidemiology of the disease, thus resulting in the renewed efforts in the search for effective control measures. Currently, live attenuated, inactivated, and immune-complex vaccines are among the immune-therapeutic approaches employed for the control of IBD in the field alongside adequate biosecurity, albeit with various degrees of success and limitations. Progress in genetic engineering has allowed the generation of reverse genetic IBDV mutants, recombinant live viral vectors expressing the IBDV VP2 immunodominant protein, intra-serotypic recombinant IBDV viral-like particle co-expressing the outer capsid protein structures derived from 2 or more serotype 1 strains or the incorporation of either VP2 or VP2-4-3 polyprotein sequences alongside molecular adjuvants that can be used as IBD vaccine candidates to elicit an immune response. However, despite these advances, outbreaks are still reported even in flocks that have up to date vaccination records and somewhat excellent management practices. This paper reviews aspect of genetic characteristics of IBDV and reflects on the progress and future challenges in providing effective IBD vaccine to achieve effective control of both classical and very-virulent IBDV serotypes that constitute a major devastation to poultry production and health. \u0000 \u0000 \u0000","PeriodicalId":253894,"journal":{"name":"Sokoto Journal of Veterinary Sciences","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131638472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Gross testicular morphometric parameters and sperm reserves in indigenous Ghanaian West African dwarf goats 加纳本土西非矮山羊的睾丸形态参数和精子储量
Sokoto Journal of Veterinary Sciences Pub Date : 2021-11-04 DOI: 10.4314/sokjvs.v19i3.9
J. Atawalna, D. Essel-Cobbinah, P.D. Akpalu, B. Emikpe
{"title":"Gross testicular morphometric parameters and sperm reserves in indigenous Ghanaian West African dwarf goats","authors":"J. Atawalna, D. Essel-Cobbinah, P.D. Akpalu, B. Emikpe","doi":"10.4314/sokjvs.v19i3.9","DOIUrl":"https://doi.org/10.4314/sokjvs.v19i3.9","url":null,"abstract":"\u0000 \u0000 \u0000The West African Dwarf (WAD) goat has genetic potentials that can be exploited for improved goat production. However, their testicular morphometric parameters and sperm reserves in Ghana are not well known. A cross-sectional study was conducted at the Sabtiu Musah abattoir in Kumasi, Ghana, to evaluate the gross testicular morphometric parameters and sperm reserves in 10 indigenous WAD goats. The samples were stored on an ice chest and transported to the Regional Veterinary Laboratory for analysis on the day of collection. In the laboratory, the testes and epididymis were separated by dissection and then freed of all connective tissue and the Tunica albuginea. The weight, length, width and volume of the testis were determined. A segment of testicular parenchyma was incised and homogenized in a 20 ml normal saline solution. The resulting homogenate was stored in the refrigerator overnight and a filtered aliquot used for estimating spermatid concentration and sperm reserves. The weight, length, width, volume of the testis and the gonadosomatic index were 70.09 ±14.19 gm, 7.46 ± 0.52 cm, 5.08 ± 0.62, cm, 102.40 ± 29.40 ml and 5.09 ± 0.07%, respectively. The sperm reserves per the whole testis, sperm reserves per gramme testis, Daily Sperm production (DSP), and DSP per gramme testis of Ghanaian WAD bucks were 146.0 ± 50.95, 2.2 ± 0.62, 41.01 ± 14.3 and 0.62 ± 0.17 x109 spermatozoa, respectively. Indigenous West African Draft goats have a high potential for sperm production. It is recommended that further research be conducted on the semen quality parameters of this breed. \u0000 \u0000 \u0000","PeriodicalId":253894,"journal":{"name":"Sokoto Journal of Veterinary Sciences","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115238035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of season on herd size and birth rate of small-holder goats in the Southern Guinea Savanna 季节对南几内亚草原小农山羊羊群规模和出生率的影响
Sokoto Journal of Veterinary Sciences Pub Date : 2021-11-04 DOI: 10.4314/sokjvs.v19i3.3
K. Anoh, I. Abdulahi, I. K. Al-Habib
{"title":"Influence of season on herd size and birth rate of small-holder goats in the Southern Guinea Savanna","authors":"K. Anoh, I. Abdulahi, I. K. Al-Habib","doi":"10.4314/sokjvs.v19i3.3","DOIUrl":"https://doi.org/10.4314/sokjvs.v19i3.3","url":null,"abstract":"\u0000 \u0000 \u0000 \u0000The study aimed to evaluate the influence of season on herd size and the birth rate of goats in Southern Guinea Savanna, Nigeria. The study was carried out in Idah, Kogi State, Nigeria. A total of 54 households from 6 villages were used for the evaluation. Structured questionnaires on the socio-economic characteristics of the goat owners were administered. Data on the reproductive performance of goats were collected by visual appraisal. The data collected were on herd size, sex, number of pregnant goats, lactating goats and newly weaned kids. The result showed that more women (63.6%) were involved in goat rearing than males (36.4%), and about 91.6% of the respondents had a herd size of 1-20 goats, while only 8.4% had a herd size of 21-30. The goat herd distribution showed that the average herd size was 16.5goats, within the range of 7 to 30 goats. The herd structure was 391 females and 184 males. Three breeds of goats were identified, the West African Dwarf (WAD) goats being the dominant (397), followed by Maradi (Red Sokoto) breed (113), and the least was Pygmy breed (75). Season significantly influenced pregnancy and the number of lactating goats. There were more lactating goats during the cold-wet period and more pregnant goats during the hot-dry season. It was concluded that goat production is still at the peasant level, and goats were kept as a supplementary source of income. The conception rate was high during the cold-dry season, which was manifested in the hot-dry season. More awareness is still needed to increase the production of goats in the area. We recommend a reproduction program should be targeted during the cold-dry season where the conception rate is high. \u0000 \u0000 \u0000 \u0000","PeriodicalId":253894,"journal":{"name":"Sokoto Journal of Veterinary Sciences","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125356489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolation and genomic characterization of “unassigned” Salmonella enterica serovars from poultry in Ilorin, north-central Nigeria 尼日利亚中北部伊洛林家禽中“未分配”肠炎沙门氏菌血清型的分离和基因组特征分析
Sokoto Journal of Veterinary Sciences Pub Date : 2021-11-04 DOI: 10.4314/sokjvs.v19i3.4
I. Raufu, O. Ahmed, A. Aremu, J. Ameh, A. Ambali
{"title":"Isolation and genomic characterization of “unassigned” Salmonella enterica serovars from poultry in Ilorin, north-central Nigeria","authors":"I. Raufu, O. Ahmed, A. Aremu, J. Ameh, A. Ambali","doi":"10.4314/sokjvs.v19i3.4","DOIUrl":"https://doi.org/10.4314/sokjvs.v19i3.4","url":null,"abstract":"\u0000 \u0000 \u0000 \u0000Salmonellosis is an important global foodborne disease caused by Salmonella enterica (S. enterica). Strains that are resistant to a variety of antibiotics were known to constitute major hazard to public health. The objectives of this study are to determine the serovar distributions, genomic antimicrobial resistance, prediction of genes conferring resistance to selected antibiotics, the multi-locus sequence typing (MLST), and plasmid replicon typing of “unassigned” S. enterica isolated from poultry. A total of 300 samples comprised of: post-mortem tissues (n = 150), cloacal swabs (n = 30), and poultry environment (n = 120) were aseptically collected and analyzed between January and June, 2017. Presumptive S. enterica isolates were characterized using conventional cultural methods, biochemical tests, and serotyping. The isolates were characterized, using Whole Genome Sequencing (WGS) Method. Five “unassigned” S. enterica serovars were recovered from four matrices (liver, n = 1; water, n = 1; cloacal swab, n = 2; poultry feed, n = 1). Prediction of point mutation in parC (T57S) was reported in two strains which confer resistance to nalidixic acid; in addition to this, prediction of fosA7 that confers resistance to fosfomycin was identified in one of these strains. Three isolates each encoded plasmid mediated quinolone resistance (PMQR) qnrB69 and bla-CMY-98 genes expected to confer decreased susceptibility to ciprofloxacin and resistance to ampicillin, amoxicillin-clavulanic acid, cefoxitin, and ceftriaxone, respectively. Three sequence types, ST-6111, 6114 and 7073 were detected. None of the isolates harbored plasmid replicon. This study highlights the importance of “unassigned” S. enterica serovars in the emergence and spread of S. enterica in poultry. There is a need for the establishment of national collaborative Salmonella program to further investigate the pathogenic and public health risk to humans, of “unassigned” S. enterica serovars in Nigeria. \u0000 \u0000 \u0000 \u0000","PeriodicalId":253894,"journal":{"name":"Sokoto Journal of Veterinary Sciences","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115846240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Seroprevalence of anti-toxoplasma gondii antibodies in free-range chickens in Kaduna metropolis, Nigeria 尼日利亚卡杜纳大都市散养鸡中抗刚地弓形虫抗体的血清流行率
Sokoto Journal of Veterinary Sciences Pub Date : 2021-11-04 DOI: 10.4314/sokjvs.v19i3.10
I. Nzelu, B.D. Shingyu, J. Kwaga
{"title":"Seroprevalence of anti-toxoplasma gondii antibodies in free-range chickens in Kaduna metropolis, Nigeria","authors":"I. Nzelu, B.D. Shingyu, J. Kwaga","doi":"10.4314/sokjvs.v19i3.10","DOIUrl":"https://doi.org/10.4314/sokjvs.v19i3.10","url":null,"abstract":"\u0000 \u0000 \u0000Free-range chickens play a vital role in the epidemiology of toxoplasmosis because they feed on the ground, exposing them to infective oocysts shed by cats that contaminate the environment. The role of chickens in the epidemiology of toxoplasmosis in Nigeria is understudied. Therefore, in the present study, we surveyed 222 free-range chickens slaughtered for human consumption in Kaduna metropolis, Nigeria, for the presence of anti-T. gondii antibodies using indirect enzyme-linked immunosorbent assay (iELISA). Of the total birds sampled, 27.9% (62/222) were seropositive. Results showed no statistically significant association between seroprevalence and sex (p > 0.05). The study has demonstrated the presence of anti-T. gondii antibodies in free-range chickens in Kaduna, Nigeria, indicative of exposure of the sampled chickens to T. gondii oocysts. Proper cooking of poultry meat obtained from the study location is advocated to avoid exposure to T. gondii. \u0000 \u0000 \u0000","PeriodicalId":253894,"journal":{"name":"Sokoto Journal of Veterinary Sciences","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121192058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lead and coliform contaminants in groundwater sources in peri-urban areas of Makurdi, Nigeria 尼日利亚马库尔迪城郊地区地下水中的铅和大肠菌群污染物
Sokoto Journal of Veterinary Sciences Pub Date : 2021-11-04 DOI: 10.4314/sokjvs.v19i3.8
R. A. Agyo, R. Ofukwu, C. Agada, A. Okoh
{"title":"Lead and coliform contaminants in groundwater sources in peri-urban areas of Makurdi, Nigeria","authors":"R. A. Agyo, R. Ofukwu, C. Agada, A. Okoh","doi":"10.4314/sokjvs.v19i3.8","DOIUrl":"https://doi.org/10.4314/sokjvs.v19i3.8","url":null,"abstract":"\u0000 \u0000 \u0000Benue State has one of the most populated state capitals in North-central Nigeria, suffering from acute water shortage despite River Benue that runs through the town. The combined effect of inadequate potable water supply and the polluted nature of the River has pushed the populace, especially peri-urban residents, to resort to water from wells and boreholes. This study investigates the possible contamination by lead, and some waterborne pathogenic bacterial burden of water from wells and boreholes. Four peri-urban areas of Makurdi, Nigeria, were selected for the study. A total of 768 samples were randomly collected, 192 from each location.The presence of lead was quantified using Atomic Absorption Spectrophotometer, while the bacteriological assessment was done using Multiple Tube Fermentation Techniques and biochemical tests. The mean value for lead at the different sampling sites ranged from 0.030 to 0.079mg/L. The mean value of lead in all the wells and locations was significantly (P<0.05) higher than the WHO recommended values of 0.01 mg/L for lead. Five species of pathogenic bacteria were isolated and identified, namely E. coli, Salmonella subsp 3B, Enterobacter pagglomeran complex, Klebsiella pneumoniae and Citrobacter freundii. The mean value for E. coli at the different well types ranged from 0.000 to 0.401 CFUX10 and were significantly (P<0.05) different. Water from wells in Makurdi had high lead concentration as well as enteric pathogenic bacteria that render it not fit for human consumption. It is recommended that regulatory agencies should protect wells through the development of relevant guidelines to address the risk of water contamination. \u0000 \u0000 \u0000","PeriodicalId":253894,"journal":{"name":"Sokoto Journal of Veterinary Sciences","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121686555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of changes in spermiogram of Shika Brown® Breeder cocks fed dietary levels of baobab (Adansonia digitata) seedmeal 饲粮中添加猴面包树(Adansonia digitata)籽粕对Shika Brown®种鸡精子图变化的影响
Sokoto Journal of Veterinary Sciences Pub Date : 2021-06-11 DOI: 10.4314/sokjvs.v19i1.9
O. G. Fanaiye, L. Okoro, M. Shinkut, U. Samuel, V. Sinkalu, I. Rekwot
{"title":"Evaluation of changes in spermiogram of Shika Brown® Breeder cocks fed dietary levels of baobab (Adansonia digitata) seedmeal","authors":"O. G. Fanaiye, L. Okoro, M. Shinkut, U. Samuel, V. Sinkalu, I. Rekwot","doi":"10.4314/sokjvs.v19i1.9","DOIUrl":"https://doi.org/10.4314/sokjvs.v19i1.9","url":null,"abstract":"This study evaluated the effects of varying levels of Baobab seed-meal (BSM) on spermiogram of Shika Brown® breeder cocks. Thirty  apparently healthy cocks aged 30 weeks with average body weight of 1.78 ± 0.03 kg were used for this study. They were acclimatized and randomly divided into three groups of 10 each. Group A (control), fed 0% BSM growers diet, groups B, (5%) and group C, (10%) BSM diets. Semen samples were collected from each cock twice weekly for 28 days and spermiogram evaluated. Results indicated significant (P< 0.05) difference for mean volume, percentage live spermatozoa, sperm gross motilities and concentration between the treatment groups (B and C) and the control group (A). Mean abnormal sperm of cocks in groups B and C were significantly (P<0.05) lower compared to group A. It was concluded that BSM is likely to improve semen characteristics in breeder cocks. Therefore, it is recommended that BSM at 5% and 10% is safe and should be incorporated into breeder cocks diet by farmers for enhanced semen characteristics.  \u0000Keywords: Baobab, Shika Brown®, spermiogram, semen, breeder","PeriodicalId":253894,"journal":{"name":"Sokoto Journal of Veterinary Sciences","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132946906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seroprevalence of contagious bovine pleuropneumonia in three selected south-eastern states of Nigeria 尼日利亚东南部三个州传染性牛胸膜肺炎的血清患病率
Sokoto Journal of Veterinary Sciences Pub Date : 2021-06-11 DOI: 10.4314/sokjvs.v19i1.7
K. C. Anyika, S. Okaiyeto, A. Sackey, C. Kwanashie, L. T. Ikpa
{"title":"Seroprevalence of contagious bovine pleuropneumonia in three selected south-eastern states of Nigeria","authors":"K. C. Anyika, S. Okaiyeto, A. Sackey, C. Kwanashie, L. T. Ikpa","doi":"10.4314/sokjvs.v19i1.7","DOIUrl":"https://doi.org/10.4314/sokjvs.v19i1.7","url":null,"abstract":"Contagious bovine pleuropneumonia is a trans-boundary animal disease caused by Mycoplasma mycoides subsp. mycoides. This study was designed to determine the seroprevalence of contagious bovine pleuropneumonia (CBPP) in three selected south eastern states (Anambra, Enugu and Imo) of Nigeria using competitive enzyme-linked immunosorbent assay (c-ELISA). A total of 438 bovine sera samples were collected randomly for four months (December 2019 to March 2020) and screened for antibodies to Mycoplasma mycoides subsp. mycoides (Mmm) using IDEXX CBPP antibody ELISA kit (CIRAD, France). Results showed an overall prevalence of 59.4% for the three states screened. Antibodies to Mmm were detected in all the three states. Enugu state had the highest prevalence (64.3%) followed by Imo state (63%) and Anambra state (50.7%). Female animals had higher prevalence of CBPP than male. However, it was not statistically significant (P> 0.05). This study confirms the presence of CBPP in south eastern Nigeria, and could be used as a base line data for future studies in this region. It is recommended that active surveillance and vaccination protocol should be undertaken in the region for the control and prevention of this disease. \u0000Keywords: c-ELISA, Contagious bovine pleuropneumonia, Mycoplasma , Nigeria, Seroprevalence","PeriodicalId":253894,"journal":{"name":"Sokoto Journal of Veterinary Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134084681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
In vitro and in vivo changes observed in Trypanosoma brucei brucei-infected rats treated with artesunate and/or diminazene aceturate 用青蒿琥酯和/或醋酸二硝基萘治疗的布氏锥虫感染大鼠的体内和体外变化
Sokoto Journal of Veterinary Sciences Pub Date : 2021-02-18 DOI: 10.4314/SOKJVS.V18I4.5
KO Jolayemi, M. Mamman, D. Sani, M. Okoronkwo, J. Amaje
{"title":"In vitro and in vivo changes observed in Trypanosoma brucei brucei-infected rats treated with artesunate and/or diminazene aceturate","authors":"KO Jolayemi, M. Mamman, D. Sani, M. Okoronkwo, J. Amaje","doi":"10.4314/SOKJVS.V18I4.5","DOIUrl":"https://doi.org/10.4314/SOKJVS.V18I4.5","url":null,"abstract":"Publication History: Received: 02-09-2020 Accepted: 14-10-2020 Abstract This study evaluated in vitro and in vivo antitrypanosomal effect of artesunate and/or diminazene aceturate in Wistar rats experimentally infected with Trypanosoma brucei brucei. In vitro screening was carried out in triplicates using 50 μl of 0.2, 2 and 20 μg/μl of artesunate as test drug; diminazene aceturate, normal saline and trypanosome-infected blood served as controls in a 96-well microtitre plate, incubated at 37 ̊C for 5 minutes. Efficacy was observed over a period of 60 minutes for reduced or complete trypanosomal immobilization. Results showed concentration-dependent cessation of trypanosomal motility was significantly (p < 0.001) induced by artesunate when compared to the controls. Seventy Wistar rats of both sexes weighing between 190 and 210 g were randomly divided into 7 groups (5 males and 5 females) are used for in vivo study. Groups I and II served as normal control and model control respectively. Groups III to VII were infected with Trypanosoma brucei brucei (10 trypanosomes/ml) intraperitoneally. At peak parasitaemia (8 days post-infection), group III was treated with diminazene aceturate (3.5 mg/kg) intramuscularly once while groups IV, V, VI were treated with artesunate (200, 100, 50) mg/kg orally for 5 consecutive days and group VII was treated with combination of artesunate (50 mg/kg) orally and diminazene aceturate (1.75 mg/kg) intramuscularly for 5 days. Results indicated pre-patent period of 4 days and increase in levels of parasitaemia post-inoculation. PCV, Hb concentration, RBC count, MCV, MCHC and total leucocyte count decreased significantly (p < 0.05) between days 0 and 8 in groups II to VII. Following treatment, significant increases (p < 0.05) were recorded except for groups II, IV, V and VI where the rats died. Thus, combination of artesunate (50 mg/kg) and half the standard dose of diminazene aceturate was able to reduce parasitaemia and ameliorate the anaemia elicited by the trypanosomes.","PeriodicalId":253894,"journal":{"name":"Sokoto Journal of Veterinary Sciences","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127044684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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