{"title":"Microcomposite ceramics modeling","authors":"V. Vereschagin, A. Sergeyev, Y. Borodin","doi":"10.1109/KORUS.1999.876239","DOIUrl":"https://doi.org/10.1109/KORUS.1999.876239","url":null,"abstract":"Computer modeling of microcomposite ceramic grain structure was carried out taking into account the correlative fields of C-particles, and the principles of high packing and self-similarity. The behavior of the spirally organized microcomposite ceramic structure model is in accordance with studies of polytypes, nano- and other mesoscopic particles. It was shown that in grains there is microplasticity within the 2D electron lattice due to the high mobility of self-organised mesoscopic particle blocks. Therefore a high level of size quantization and microplasticity intergrain structure is reached under low temperatures.","PeriodicalId":250552,"journal":{"name":"Proceedings Third Russian-Korean International Symposium on Science and Technology. KORUS'99 (Cat. No.99EX362)","volume":"209 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1999-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115735373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The typical dwelling house of Novonicolaevsk (modern Novosibirsk) at the beginning of 20th century","authors":"N.P. Zhurin","doi":"10.1109/KORUS.1999.875882","DOIUrl":"https://doi.org/10.1109/KORUS.1999.875882","url":null,"abstract":"","PeriodicalId":250552,"journal":{"name":"Proceedings Third Russian-Korean International Symposium on Science and Technology. KORUS'99 (Cat. No.99EX362)","volume":"221 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1999-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123309991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fibrinolytic serine protease from spirodela polyruiza","authors":"Hye-Seon Choi","doi":"10.1109/KORUS.1999.876194","DOIUrl":"https://doi.org/10.1109/KORUS.1999.876194","url":null,"abstract":"A serine protease was purified from Chinese herb (Spirodelapolyrhiza). Protease has a molecular mass of 180,000 dalton and 43,000 dalton in gel filtration and SDS-PAGE, respectively, implying it is a trimer. Its optimum pH was 4.5-5.0. Enzyme was stable below 42C0 and after lyophilization. The enzyme activity was inhibited significantly by leupeptin and to less degree by PMSF. The protease hydrolyzed not only fibrin but also fibrinogen, cleaving A and B without affecting chain of fibrinogen. However, no hydrolysis was found with hemoglobin, immunoglobulin, and albumin under the same condition. It cleaved preferentially Arg or Lys residue of synthetic substrates (P' position). The enzyme had an anticoagulatory activity measured with activated partial thromboplastin time and thrombin time test. It delayed APTT and TT two times at the protein concentration of 5.0 and 5.7 ug, respectively and drastically reduced after heat treatment. Introduction Blood clots are formed fiom fibrinogen by thrombin and are lyzed by plasmin, which is activated from plasminogen by tissue plasminogen activator (tPA). The blood clotting and lysis systems are tightly regulated. Its disturbance results in serious cardiovascular disease and cerebral infarction. The factors involved in fibrinolysis and thrombolysis are a promising target for chemotherapy (1 -3). Hemorrhagic toxin from the snake venom of Crotalus atrox (4), fibrinolytic and thrombolytic agents from Lumbricus rubellus ( 5 ) and anticoagulant, hirudin from Hirudo medicinalis (6), fibrinolytic protease fiom Pleurotus ostreatus (7) and FZammuZina velutipes (8) have been reported and characterized. We have purified and characterized a fibrinolytic protease fiom Spirodela polyrhiza. The protease showed anticoagulant activity probably due to its fibrinolytic and thrombolytic activity. This enzyme may be useful in clinical applications for fibrinolysis and thrombolysis. . Results Purification and molecular properties. Protease activity was detected from crude extracts of Spirodela polyrhiza and purified using an assay with Z-Lys-SBzl as a substrate. The enzyme was bound tightly to phenyl Sepharose and eluted with 10 mM Tris-HC1, pH 7.0. It was eluted with arginine through an affinity column of p-aminobezamidine Agarose. Finally purified protease was obtained after FPLC , phenylsuperose column chromatography. The enzyme was elecrophoretically homogeneous. The molecular mass of purified enzyme was determined to be 180,000 dalton in Sephadex G-150 gel filtration column and 43,000 dalton in SDS-PAGE, indicating that the enzyme is a tetramer. The PI of the protein was estimated to bc: pH 8.0 from a chromatofocusing column chromatography. Effect of pH on the enzyme activity was tested with various buffers. Maximum activity was found in the range of 4.5 to 5.0, indicating it is a aicdic protease. Thermal stability of purified protease was determined after treatment at different temperatures for 15 min. Half the activity was l","PeriodicalId":250552,"journal":{"name":"Proceedings Third Russian-Korean International Symposium on Science and Technology. KORUS'99 (Cat. No.99EX362)","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1999-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115098800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Filtering of stochastic systems in the case of continuous-discrete time channels of observations with memory in the presence of anomalous interferences in the discrete channels with reservation","authors":"N. Dyomin, S. Rozhkova, O. Rozhkova","doi":"10.1109/KORUS.1999.875920","DOIUrl":"https://doi.org/10.1109/KORUS.1999.875920","url":null,"abstract":"The article considers the problem of state vector filtering of a stochastic system in continuous time. It is based on the realization processes set with continuous and discrete time in the presence of anomalous interferences in discrete channels with reservation.","PeriodicalId":250552,"journal":{"name":"Proceedings Third Russian-Korean International Symposium on Science and Technology. KORUS'99 (Cat. No.99EX362)","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1999-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116024622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A decision support system for short-term shop control within holonic manufacturing environment","authors":"Hong-Seok Park, G. Son","doi":"10.1109/KORUS.1999.875926","DOIUrl":"https://doi.org/10.1109/KORUS.1999.875926","url":null,"abstract":"Conflicts and interruptions caused by resource failures and rush orders require a nonlinear dynamic production management. Present systems of production control do not meet these requirements because of their rigid concepts. Starting with the grasp of the disadvantages of current approaches, the paper develops a control structure that enables systems to react independently to malfunctions. The tolerant control concept is used to compensate for disturbances. On the other hand, in other to handle the complexity of job allocation and the existence of many disparities, a powerful modeling method, fuzzy Petri nets, is introduced. On the basis of this model, the developed system optimizes the actual machine allocations by rule based decision.","PeriodicalId":250552,"journal":{"name":"Proceedings Third Russian-Korean International Symposium on Science and Technology. KORUS'99 (Cat. No.99EX362)","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1999-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129304615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Design of the adaptive noise canceler using neural network with backpropagation algorithm","authors":"Hyung-Suk Chu, C. An","doi":"10.1109/KORUS.1999.876276","DOIUrl":"https://doi.org/10.1109/KORUS.1999.876276","url":null,"abstract":"In this paper, an adaptive noise canceller using a neural network with backpropagation is designed. The adaptive noise canceller using the least mean square algorithm has the large correlativity of the reference signal and shows the limitation of the big signal to noise ratio. The system proposed in this paper plays an important role in denoising these signals. In addition, the experiments are carried out to analyze the effects of the number of hidden layers and nodes about the system. The performance of the proposed adaptive noise canceller is compared with that of the system which is used the least mean square algorithm.","PeriodicalId":250552,"journal":{"name":"Proceedings Third Russian-Korean International Symposium on Science and Technology. KORUS'99 (Cat. No.99EX362)","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1999-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130346347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of different configurations of varactor-tuned resonant circuits","authors":"B. Kapilevich, R. Lukjanets","doi":"10.1109/KORUS.1999.876265","DOIUrl":"https://doi.org/10.1109/KORUS.1999.876265","url":null,"abstract":"This paper presents an analysis of varactor tunable microstrip resonators (VTMR) using proper circuit models. The resonance conditions have been obtained and applied to determine better configurations of VTMRs. The behaviour of resonance conditions has been discussed and compared for different tunable resonator configurations. Based on nonlinear optimization, coupling elements stabilizing the bandwidth have been suggested.","PeriodicalId":250552,"journal":{"name":"Proceedings Third Russian-Korean International Symposium on Science and Technology. KORUS'99 (Cat. No.99EX362)","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1999-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126686565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Characterization of vasoactive intestinal peptide on hematopoiesis","authors":"S. Ju, B. Kim, K. Kwack, S. Park","doi":"10.1109/KORUS.1999.876192","DOIUrl":"https://doi.org/10.1109/KORUS.1999.876192","url":null,"abstract":"Vasoactive intestinal peptide(V1P) is reported to modulate immune responses. In this study, we evaluated the role of VIP in hematopoiesis. Stem cells isolated from cord blood was treated with VIP for up to 15 days. Cell sizes, CD4 1 expression and polyploidity was analyzed by flow cytometry. VIP increased cell sizes of stem cells, percentage of CD41 positive cells and polyploidities. VIP produced synergistic effects when co-treated with thrombopoietin(TPO), which is known to be a major cytokine responsible for megakaryocytopoiesis. These results indicates that VIP might be one of the regulator for megakyryocytopoiesis and the administration of VIP with TPO might have the potential of accelerating platelet recovery after chemotherapy or stem cell transplantation. Our results might also be applicable for the expansion of megakaryocyte progenitor cells in vitro. Introduction Vasoactive intestinal peptide(V1P) is a 28 amino acid neuropeptide that is widely distributed in mammalian tissues( 1). The name, VIP, was coined to describe its potent vasodilatory action in lung tissue(2). VIP function as a neurotransmitter, a hormone, and also as an immune regulator,(3) but, to our knowledge, a possible role in hematopoiesis has not been explored. Neuropeptide modulation of the immune response has been well documented(4,5). The effects of VIP, somatostatin, and substance P on immune functions are mediated via specific, high affinity receptors on both T and B lymphocytes as well as on monocytes(6-9). VIP modulates lymphocytes proliferation, IgA production, natural killer cell cytotoxicity, and lymphocyte migration. Recently, neuropeptides have been shown to regulate hematopoiesis( 10-1 1). Substance P regulates hematopoiesis by inducing the release of IL-3 and granulocyte-macrophage colony stimulating factor fkom bone marrow(BM) mononuclear cells( 10). Thrombopoietin(TP0) is considered to be the primary growth factor for regulating megakaryocytopoiesis and thrombopoiesis. In both mouse and human, TPO supports the differentiation and proliferation of megakaryocyte progenitor cells and it is essential for the complete maturation of megakaryocytes in vitro( 12). In the present study, we used a liquid culture system to facilitate flowcytometric analysis. TPO selectively stimulated the growth of megakaryocytic cells from CD34+ cord blood cells. We also demonstrate a new property of VIP and indicate that VIP is a new regulatory protein of normal megakaryocyte development. Materials and Methods Collection of cord blood (CB): Cord blood samples were aspirated in heparinized plastic syringes from the umbilical vein at normal delivery. Blood was collected in tubes containing heparin (1 0 U/ml) and was stored at 2-6 0 until processed within 24 hr after collection. , Purification of haemopoietic progenitor cells: After collection CB was separated by density centrifbgation over Percoll(Pharmacia, Sweden). The mononuclear cells(MNCs) were collected 0-7803-5729-9/99/$10.00","PeriodicalId":250552,"journal":{"name":"Proceedings Third Russian-Korean International Symposium on Science and Technology. KORUS'99 (Cat. No.99EX362)","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1999-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129302750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Regrouping cation n-oximethylanilinty in the O-/spl sigma/-complex","authors":"V. Bochkarev, L. S. Soroka","doi":"10.1109/KORUS.1999.876241","DOIUrl":"https://doi.org/10.1109/KORUS.1999.876241","url":null,"abstract":"By means of the MNDO semi-empirical method, possible ways of the regrouping N-oximethylaniliniy cation (rr\") in the o-a-complex (0-S) are considered. The results of account testify, that the regrouping can proceed on two alternative mechanisms. Introduction The aniline acts as nucleophil with several reactionary centers in the reaction with formaldehyde. The products of the addition and condensation formaldehyde during synthesis of the diaminodiphenylmetan and anilineformaldehyde resins are obtained both on the aminogroup and on the aromatic ring of aniline [l]. The relative yield of the products reaction depends from following factors: temperature, ratio reactants, PH and catalyst used. The stability and relative reactionary ability of the intermediate played the important role in this case [2]. Earlier [3] we estimated relative stability and reactionary ability of the possible intermediates of the aniline interaction with formaldehyde the under acid catalysis conditions. According to results of calculations, protonated alcohol amine, 0-, mand p-a-complexes are formed through dipole-ionic complex, From low temperatures and kinetic control of reaction, the primary product of addition of the formaldehyde to aniline should be alcohol amine according to the obtained results. From the increasing of the temperature and the process duration oximethylol aniline derivative, mainly pand o-isomerics are obtained. Main part In the present work by means of the MNDO method, possible ways of the regrouping N-oximethylaniliniy cation (T') in o-o-complex (0-S) are considered. The distance between atom of the formaldehyde carbon C15 and atom C2 of aniline as coordinate of reaction was chosen. All other geometrical parameters of the reacting system ( bond length, valence and torsion angles were optimized. formation has effect on insignificant geometrical parameters benzol ring of aniline. The formation of new NI2-CI5 bond leads not only to transfer of pair electrons from donor atom but also to infringement atom nitrogen conjugation of with benzol ring. Increase of the CI-N12 bond length from 1,4232 to 1,4773, increase of the negative charge on CI atom and positive charge on C4,' change population of the atomic orbital CI and C4 atoms, the reduction CI-NI2 bond order testifies to it. It is necessary to note the low order of the bond formed NI2-CI5 (0,7751 u.) and the charge transference from oximethyl-cation to the aniline (0,639 u.). It indicates the high labiality of the oximethyl group in the r'; on its ability to participate in various secondary reactions, including reactions of the regrouping. In view of asymmetry oximethyl groups considered intermediates can exist as several rotary stereoisomers. For is anti-form, and for 0-S is orientation of OH-group to the aminogroup. The The comparison of structure r' with initial reactant structures shows, that the 0-7803-5729-9/99/$10.00","PeriodicalId":250552,"journal":{"name":"Proceedings Third Russian-Korean International Symposium on Science and Technology. KORUS'99 (Cat. No.99EX362)","volume":"279 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1999-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114622495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Singularities of external and internal aerodynamics of the various forms of shells cooling tower","authors":"V. Larichkin","doi":"10.1109/KORUS.1999.875865","DOIUrl":"https://doi.org/10.1109/KORUS.1999.875865","url":null,"abstract":"","PeriodicalId":250552,"journal":{"name":"Proceedings Third Russian-Korean International Symposium on Science and Technology. KORUS'99 (Cat. No.99EX362)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1999-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116347053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}