International Journal of Orofacial Research最新文献

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Oral Health and Salivary pH Changes in Menopausal Women: A Cross-sectional Study 更年期妇女口腔健康和唾液pH值变化:一项横断面研究
International Journal of Orofacial Research Pub Date : 2023-07-10 DOI: 10.56501/intjorofacres.v7i1.845
Shilpa Prasad, Durgadevi Pancharethinam, S. Gokulraj, K. A
{"title":"Oral Health and Salivary pH Changes in Menopausal Women: A Cross-sectional Study","authors":"Shilpa Prasad, Durgadevi Pancharethinam, S. Gokulraj, K. A","doi":"10.56501/intjorofacres.v7i1.845","DOIUrl":"https://doi.org/10.56501/intjorofacres.v7i1.845","url":null,"abstract":"Introduction: Menopause is a natural process in life of women often associated with hormonal changes. It affects oral health by influencing the growth of bacteria and plaque, which can cause tooth decay and gum disease. Menopause can alter salivary pH by reducing estrogen levels, which may lead to dry mouth, inflammation, and increased risk of infections. Therefore, it is important for women in menopause to monitor their salivary pH and maintain good oral hygiene habits. However, there is contradictory evidence about the level of salivary pH and oral symptoms. The present study was carried out to assess the oral findings and salivary pH in premenopausal and postmenopausal women. Methods: The study was carried out on 60 patients who reported to the Department of oral medicine and radiology and were divided into two groups consisting of 30 patients each. Group 1: premenopausal women with no known systemic illness and deleterious habits. Group 2: postmenopausal women. Results: Salivary pH is higher in postmenopausal women than in premenopausal women. Both pre and postmenopausal women have oral symptoms such as dry mouth, facial pain, and ulcerative lesions, but they are more frequent in postmenopausal women. Conclusions: Menopause affects the oral health and salivary pH of women. Postmenopausal women are more prone to oral diseases and have lower salivary pH than premenopausal women. Salivary pH may be used as a biomarker for oral health status in postmenopausal women.","PeriodicalId":245370,"journal":{"name":"International Journal of Orofacial Research","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122421040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparative evaluation of microleakage among new composites FILTEK Z350 XT, TETRIC N-CREAM, and CLEARFIL AP-X: An In Vitro Study 新型复合材料FILTEK Z350 XT、TETRIC N-CREAM和CLEARFIL AP-X的体外微泄漏比较研究
International Journal of Orofacial Research Pub Date : 2023-07-01 DOI: 10.56501/intjorofacres.v7i1.865
Priya Badkul, Muktishree Mahendra, Anjali Bichpuriya, Amruta Vaidya
{"title":"A comparative evaluation of microleakage among new composites FILTEK Z350 XT, TETRIC N-CREAM, and CLEARFIL AP-X: An In Vitro Study","authors":"Priya Badkul, Muktishree Mahendra, Anjali Bichpuriya, Amruta Vaidya","doi":"10.56501/intjorofacres.v7i1.865","DOIUrl":"https://doi.org/10.56501/intjorofacres.v7i1.865","url":null,"abstract":"Introduction: Modern composites promise to improve fracture resistance, reduce postoperative sensitivity and marginal discoloration. They have also been reported to reduce microleakage, which can lead to restoration failure and tooth loss. A comparative evaluation of microleakage among newer composites FILTEK Z350 XT, TETRIC N-CREAM, and CLEARFIL AP-X was carried out to assess their efficacy in reducing marginal microleakage. Methods: The study’s samples consisted of 45 upper maxillary premolar teeth. These teeth, whose sizes varied, were removed for orthodontic reasons. Class II were prepared in teeth under aseptic conditions. The specimens were divided into three experimental groups of fifteen teeth each (n = 15) and the prepared cavities were restored with nanocomposite FILTEK Z350XT (Group-I), TETRIC N-CERAM (Group-II), and micro hybrid CLEARFIL AP-X (Group III). All the teeth were immersed in methylene blue stain to explore the microleakage. Specimens were sectioned buccolingually through the restoration using diamond disc. The restorations were assessed for presence of microleakage and examined under stereo-microscope of 40X magnification to assess the microleakage. One-way ANOVA and Unpaired student t-test analysis was carried out. Results: The mean scores of microleakage showed higher values at the gingival region for Group I and Group II, while Group III exhibited higher mean scores at the occlusal region. Further, the least microleakage was observed in TETRIC N-CERAM followed by FILTEK Z350XT followed by CLEARFIL AP-X. Conclusion: None of the composites tested completely prevented microleakage, but there were significant differences among them. TETRIC N-CERAM was the most effective material in reducing microleakage compared to FILTEK Z350XT and CLEARFIL AP-X.","PeriodicalId":245370,"journal":{"name":"International Journal of Orofacial Research","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122223839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of prevalence of dental erosion in swimmers in the metropolitan city of India: A cross-sectional study 评估在印度大都市游泳者的牙齿侵蚀患病率:一项横断面研究
International Journal of Orofacial Research Pub Date : 2023-07-01 DOI: 10.56501/intjorofacres.v7i1.776
Manoj Ramugade, Kishor Sapkale, Sapna Sonkurla, Abrar Sayed
{"title":"Evaluation of prevalence of dental erosion in swimmers in the metropolitan city of India: A cross-sectional study","authors":"Manoj Ramugade, Kishor Sapkale, Sapna Sonkurla, Abrar Sayed","doi":"10.56501/intjorofacres.v7i1.776","DOIUrl":"https://doi.org/10.56501/intjorofacres.v7i1.776","url":null,"abstract":"Introduction: Development and research in medical sciences have increased the life expectancy of the masses resulting in the retention of more teeth in the oral cavity. This leads to the occurrence of various wasting diseases of teeth like attrition, abrasion, and erosion.\u0000Aim and Objectives: This study evaluates the prevalence of Dental Erosion (DE) and its severity among swimmers of chlorinated pool water in a metropolitan city in India.\u0000Material and Methods: In this study, 508 young and adult regular swimmers (including competitive swimmers) from various swimming pools were selected and examined clinically for the presence of DE. A structured questionnaire form was formulated to record the history of habitual swimming activity, diet, gastroesophageal reflux disease, history of intake of medications and acidic beverages, etc. for each swimmer. The data obtained were analysed and statistically evaluated.\u0000Result: Among 508 swimmer participants, 429 were males and 79 were females. Out of these 338 (66.54%), including 293 (57.67%) male and 45 (8.8%) female swimmers showed DE. The mean age of the swimmer was 33.64 years. The majority of swimmers showed Grade I (n=260, 76.92%) type severity followed by Grade II (n=73, 21.59%) and Grade III (n=5, 1.47%). 79 (15.55%) swimmers showed teeth sensitivity. The statistical test showed a positive correlation between the duration of swimming activity and the non-use of dental protective measures with the severity of DE (P<0.05).\u0000Conclusion: Swimmer’s erosion is mainly attributed to the acidic pH of pool water associated with chlorine amount and its severity depends upon the duration and period of swimming irrespective of the swimmer’s gender.","PeriodicalId":245370,"journal":{"name":"International Journal of Orofacial Research","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131418469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of the gender-identifying abilities of different odontometry methods - A Retrospective cross-sectional Study 不同验牙方法的性别识别能力分析-一项回顾性横断面研究
International Journal of Orofacial Research Pub Date : 2023-04-03 DOI: 10.56501/intjorofacres.v7i1.770
Manoj Ramugade, Manasi R. Mulay, Kishor Sapkale, Abrar Sayed, Suryakant Powar, Sapna Sonkurla
{"title":"Analysis of the gender-identifying abilities of different odontometry methods - A Retrospective cross-sectional Study","authors":"Manoj Ramugade, Manasi R. Mulay, Kishor Sapkale, Abrar Sayed, Suryakant Powar, Sapna Sonkurla","doi":"10.56501/intjorofacres.v7i1.770","DOIUrl":"https://doi.org/10.56501/intjorofacres.v7i1.770","url":null,"abstract":"Introduction: It is critical to identify the person in a criminal investigation process. Forensic odontology helps in the identification of the person using dentofacial structures as a differentiating tool in the criminal justice system. Several oro-dental anatomical landmarks like palate, lips and bite marks, teeth such as maxillary central incisors, canines and molars have been used in the identification of the gender of an individual based on the principle of individuality.\u0000Aims and objectives: Studying different odontometric methods such as palatal depth, mandibular canine index and maxillary inter-canine width for sex determination and compare it with the actual gender of an individual.\u0000Methodology: For this study, 72 pairs of orthodontic study models were analysed for gender determination based on three odontometric parameters viz. palatal depth, mandibular canine index and maxillary inter-canine width. The patient’s sex was not disclosed to the investigators until the completion of the model analysis. The measurements were taken using brass wire, divider, stainless steel scale and digital vernier calliper. The data was calculated and tabulated in a master chart and statistical analysis was done.\u0000Result: The results of odontometric measurement methods used for the gender determination study are in actual agreement with 32.6% male and 63.04% female population of Mumbai and the sub-urban region.\u0000Conclusion: The palatal depth, maxillary inter-canine width and mandibular canine index are simple, convenient, reproducible and reliable odontometric methods in the gender determination of individuals.","PeriodicalId":245370,"journal":{"name":"International Journal of Orofacial Research","volume":"125 8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129295963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Magnetic Resonance Imaging in the evaluation of Trigeminal Neuralgia: a pilot study 磁共振成像在评估三叉神经痛中的作用:一项初步研究
International Journal of Orofacial Research Pub Date : 2023-04-03 DOI: 10.56501/intjorofacres.v7i1.780
Rohini Bhosale, Bhavana Murjani, E. Ramaswami, Sonali Kadam, Sandesh Suryawanshi, Surabhi Srivastava
{"title":"The Role of Magnetic Resonance Imaging in the evaluation of Trigeminal Neuralgia: a pilot study","authors":"Rohini Bhosale, Bhavana Murjani, E. Ramaswami, Sonali Kadam, Sandesh Suryawanshi, Surabhi Srivastava","doi":"10.56501/intjorofacres.v7i1.780","DOIUrl":"https://doi.org/10.56501/intjorofacres.v7i1.780","url":null,"abstract":"Introduction\u0000Trigeminal neuralgia is a debilitating painful condition affecting one or more branches of trigeminal nerve characterized by sharp shooting, electric shock like pain lasting for a short time. In most cases, no specific cause can be identified but certain do tend to occur due to lesions or damage to the trigeminal nerve due to vascular compression, tumors, etc. which can be detected by magnetic resonance imaging. Hence, this pilot study was conducted to identify any underlying causes for trigeminal neuralgia using magnetic resonance imaging.\u0000Methods\u0000 A prospective cross-sectional descriptive study was conducted on 10 patients who were presented to department with clinical symptoms of trigeminal neuralgia. Magnetic resonance imaging of the brain with trigeminal protocol was conducted. The evaluation of the entire course of the trigeminal nerve was then performed by an experienced radiologist.\u0000Results\u0000Out of the 10 patients, 6 were females and 4 males. Four patients did not show presence of any pathology i.e. were idiopathic. Five cases reported with neurovascular compression and one showed the presence of a tumor at the cerebellopontine angle compressing the nerve.\u0000Conclusion\u0000In this study, with use of magnetic resonance imaging, a 60% occurrence of an underlying pathology was demonstrated which could be treated to relieve the neuralgia. Hence, taking into account the high prevalence of etiological factors which could contribute towards trigeminal neuralgia detected on MRI, large scale studies can be considered for the same. ","PeriodicalId":245370,"journal":{"name":"International Journal of Orofacial Research","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125611991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A gender determination using mandibular canine index – a prospective study on Mumbai population and comprehensive review 用下颌犬指数测定性别——孟买人口的前瞻性研究及综合综述
International Journal of Orofacial Research Pub Date : 2022-12-14 DOI: 10.56501/intjorofacres.v6i2.548
Mithileshwari Bajirao Patil, M. Sardar, J. Tupkari, Anuradha Sinha, Z. D’souza, Sarang G. Sonawane
{"title":"A gender determination using mandibular canine index – a prospective study on Mumbai population and comprehensive review","authors":"Mithileshwari Bajirao Patil, M. Sardar, J. Tupkari, Anuradha Sinha, Z. D’souza, Sarang G. Sonawane","doi":"10.56501/intjorofacres.v6i2.548","DOIUrl":"https://doi.org/10.56501/intjorofacres.v6i2.548","url":null,"abstract":"Background: Teeth is considered a necessitous auxiliary in skeletal age, and determination of gender because teeth have post-mortem destruction and fragmentation resistance and they are last to be destroyed under extreme conditions like temperature, acid, or putrefaction. \u0000Aims: To evaluate the differences in odontometrics of mandibular canine between males and females and assessment of gender by calculating differences in the mandibular canine index (MCI) of male and female subjects. \u0000Settings and Design: Prospective, cross-sectional study. \u0000Subjects and methods: This study focus on evaluation of the existence of sexual dimorphism in the Mumbai population which included permanent mandibular canine of 100 male & 100 female subjects of age group 21 to 28 years. The mesio-distal width (MDW) of right and left canine and inter-canine distance (ICD) were measured. Subsequently, the mandibular canine index was calculated. \u0000Results: No evidence of any significant statistical difference between the right and left mandibular canines among the same gender, but when compared between male and female, mandibular left canine exhibited greater sexual dimorphism (10 %) as compared with the right canine (9.2 %). The standard MCI value for the Mumbai population was 0.24. \u0000Conclusions: MCI technique can be used as one of the simple, reliable, and adjuvant diagnostic method for gender determination in forensic dentistry. As it is influenced by various factors like genetics, epigenetics, geographical locations, etc.; it is recommended to carry out population based studies so that standardized values will help in gender determination precisely.","PeriodicalId":245370,"journal":{"name":"International Journal of Orofacial Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129937575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reliability of CBCT in working length determination for successful endodontic treatment- an in vitro study CBCT在牙髓治疗工作长度测定中的可靠性-一项体外研究
International Journal of Orofacial Research Pub Date : 2022-12-14 DOI: 10.56501/intjorofacres.v6i2.542
Suparna Kosta, Neelam Chandwani, Pooja Bopche
{"title":"Reliability of CBCT in working length determination for successful endodontic treatment- an in vitro study","authors":"Suparna Kosta, Neelam Chandwani, Pooja Bopche","doi":"10.56501/intjorofacres.v6i2.542","DOIUrl":"https://doi.org/10.56501/intjorofacres.v6i2.542","url":null,"abstract":"Aim: To evaluate and compare the accuracy of working length determination using Radiovisiography, Cone Beam Computed Tomography and Actual working length of the tooth.\u0000Material and Methods: After the access cavity preparation in seventy- two  extracted human single rooted teeth, the working length was measured, using Radiovisiography and Cone beam Computed Tomography and its accuracy was compared with the actual working length of the teeth using surgical loupes. Unpaired ‘t’ test was used to test the significance of difference observed in mean working length measurements.\u0000Results:. The difference in distribution of readings was found insignificant (p<0.75) by Chi square analysis. The result showed that cone beam computed tomography working length had high percentage of accurate readings as compared to radiographic working length readings. The results also showed high Karl Pearson’s correlation coefficient between the actual working length, radiographic and CBCT working length.\u0000Conclusions: Cone beam computed tomography (CBCT) imaging is as accurate and valuable adjunct as the actual working length in determining working length.\u0000Clinical Significance: Considering the availability of CBCT and its wide implication in endodontics, there is a need to explore if CBCT can be used as a tool at par with the actual working length determination in endodontics.","PeriodicalId":245370,"journal":{"name":"International Journal of Orofacial Research","volume":"539 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123371127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical, Radiological features of Calcifying Epithelial Odontogenic Tumor: Report of two rare cases 钙化上皮性牙源性肿瘤的临床、影像学特征:附2例罕见病例报告
International Journal of Orofacial Research Pub Date : 2022-11-08 DOI: 10.56501/intjorofacres.v6i2.507
Omkar Kharat, E. Ramaswami, Surabhi Srivastava, Rashmi Ingle, Jayant S Landage, T. Chettiankandy
{"title":"Clinical, Radiological features of Calcifying Epithelial Odontogenic Tumor: Report of two rare cases","authors":"Omkar Kharat, E. Ramaswami, Surabhi Srivastava, Rashmi Ingle, Jayant S Landage, T. Chettiankandy","doi":"10.56501/intjorofacres.v6i2.507","DOIUrl":"https://doi.org/10.56501/intjorofacres.v6i2.507","url":null,"abstract":"The calcifying epithelial odontogenic tumor (CEOT) is a rare benign odontogenic tumor constitutes around 1% of all odontogenic tumours involving the jaw. The intraosseous and extraosseous variant constitutes about 95% and 5% of CEOT respectively. We have reported two CEOT cases. One is associated with an impacted left third molar in the maxilla of 39-year-old female patient, and the other with a sessile soft tissue gingival mass in the left molar region of a 30-year-old female patient. It also emphasizes the importance of advanced imaging and peculiar findings of computed tomography in diagnosing this rare tumour. The visualization of the internal structure of the lesion and the involvement of the neighbouring structures were considered very helpful for diagnosis and treatment planning. Early detection and treatment planning for such rare cases is required to prevent further complications. ","PeriodicalId":245370,"journal":{"name":"International Journal of Orofacial Research","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124671190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ameloblastoma of Anterior Mandible: Case Report 前颌骨成釉细胞瘤1例
International Journal of Orofacial Research Pub Date : 2022-11-08 DOI: 10.56501/intjorofacres.v6i2.476
Himanshu Dhanodkar, Bhupesh Bagulkar, Shradha G Jaiswal
{"title":"Ameloblastoma of Anterior Mandible: Case Report","authors":"Himanshu Dhanodkar, Bhupesh Bagulkar, Shradha G Jaiswal","doi":"10.56501/intjorofacres.v6i2.476","DOIUrl":"https://doi.org/10.56501/intjorofacres.v6i2.476","url":null,"abstract":"Churchill gave the term “Ameloblastoma”. According to Robinson it is a “usually unicentric, nonfunctional, intermittent in growth, anatomically benign and clinically persistent tumor”. It is a benign odontogenic tumor originating from residual epithelium of the tooth germ, epithelium of odontogenic cysts stratified squamous epithelium and epithelium of the enamel organ. Histopathologically, it occurs in six patterns: plexiform, follicular, acanthomatous, granular cell, basal cell, and desmoplastic type.  It is the second most common odontogenic neoplasm. It accounts for 11% of all odontogenic tumors and is characterized by slow growth and local infiltration into the adjacent tissues. About 80 % of ameloblastomas occur in the mandible, it frequently involves molar and mandibular angle (70 %), premolar (20 %), and rarely anterior region (10 %). Itis seen in adults in the third to fifth decade of life. Here, we are presenting a case of a 46-year-old male presented with a swelling in right anterior mandible diagnosed with plexiform ameloblastoma.","PeriodicalId":245370,"journal":{"name":"International Journal of Orofacial Research","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128455861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Omics’ in oral cancer: A comprehensive review 组学在口腔癌中的应用综述
International Journal of Orofacial Research Pub Date : 2022-11-08 DOI: 10.56501/intjorofacres.v6i2.152
S. Sachdev, M. A. Sardar, J. Tupkari, T. Chettiankandy, S. Dalvi, Z. D’souza
{"title":"Omics’ in oral cancer: A comprehensive review","authors":"S. Sachdev, M. A. Sardar, J. Tupkari, T. Chettiankandy, S. Dalvi, Z. D’souza","doi":"10.56501/intjorofacres.v6i2.152","DOIUrl":"https://doi.org/10.56501/intjorofacres.v6i2.152","url":null,"abstract":"Health and disease states are dictated or accompanied by corresponding alterations in genes, mRNAs, proteins and metabolites. Over the past few decades, various ‘omic’ technologies have been developed to study the genome, transcriptome, proteome and metabolome respectively. Since oral cancers are one of the leading causes of death globally, much of research work has attempted to study the analytes in cancerous conditions by utilizing the various ‘omic’ modalities. These studies have aimed to understand the pathogenesis of head and neck cancers, aid in their diagnosis, devise new treatment strategies, and improve prognosis. It is imperative for surgeons and pathologists to be in line with the updates pertaining to various ‘omic’ methodologies available for studying the analytes. The present review comprehensively describes the development of various ‘omic’ technologies, including- genomics, transcriptomics, proteomics and metabolomics, while emphasizing their applicability in oral cancers.","PeriodicalId":245370,"journal":{"name":"International Journal of Orofacial Research","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114083135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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