Middle East Journal of Internal Medicine最新文献_第4页

Diagnosis of Porphyria after Sternotomy for Severe Calcific Coronary Artery Disease : A Case Report 严重钙化性冠状动脉疾病胸骨切开术后卟啉症的诊断1例

Middle East Journal of Internal Medicine Pub Date : 2017-04-01 DOI: 10.5742/MEIM.2017.92937

Fuad M. Al-Azzam, S. Altarabsheh, M. Khasawneh

引用次数: 0

White Coat Hypertension May Be an Initial Sign of an Accelerated Atherosclerotic Process 白大衣高血压可能是动脉粥样硬化过程加速的最初征兆

Middle East Journal of Internal Medicine Pub Date : 2017-04-01 DOI: 10.5742/MEIM.2017.92940

M. Helvaci, O. Ayyıldız, Orhan Ekrem Muftuoglu

{"title":"White Coat Hypertension May Be an Initial Sign of an Accelerated Atherosclerotic Process","authors":"M. Helvaci, O. Ayyıldız, Orhan Ekrem Muftuoglu","doi":"10.5742/MEIM.2017.92940","DOIUrl":"https://doi.org/10.5742/MEIM.2017.92940","url":null,"abstract":"Background: Role of white coat hypertension (WCH) is unknown in metabolic syndrome. Methods: The study was performed in the Internal Medicine Polyclinic. Results: The study included 1,068 patients (628 females). Prevalence of excess weight increased from the third (28.7%) up to the seventh decades (87.0%), gradually (p<0.05 nearly in all steps), and then decreased in the eighth decade of life (78.5%, p<0.05). The most significant increase was detected during the passage from the third to the fourth decade (28.7% versus 63.6%, p<0.001) parallel to the smoking. Similarly, hypertriglyceridemia, hyperbetalipoproteinemia, dyslipidemia, impaired glucose tolerance (IGT), and WCH increased up to the seventh decade of life and decreased afterwards (p<0.05 nearly in all steps). On the other hand, hypertension (HT), type 2 diabetes mellitus (DM), and coronary heart disease (CHD) always increased without any decrease by decades (p<0.05 nearly in all steps) indicating their irreversible properties. Conclusion: Probably metabolic syndrome is an accelerated atherosclerotic process all over the body. It includes some reversible parameters such as smoking, alcohol, sedentary life style, animal-rich diet, overweight, hypertriglyceridemia, hyperbetalipoproteinemia, dyslipidemia, impaired fasting glucose, IGT, and WCH for the development of terminal illnesses such as early aging, obesity, DM, HT, peripheric artery disease, chronic obstructive pulmonary disease, cirrhosis, CHD, and stroke. The terminal illnesses are mainly due to the chronic inflammatory process on the arterial endothelial systems due to the much higher blood pressure in them. WCH may be an initial sign of the accelerated atherosclerotic process that can be detected easily.","PeriodicalId":243742,"journal":{"name":"Middle East Journal of Internal Medicine","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126031055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Anthracycline versus Non-Anthracycline Induction Regimens in Patients with De Novo Acute Myeloid Leukemia 蒽环类药物与非蒽环类药物诱导方案在新生急性髓系白血病患者中的应用

Middle East Journal of Internal Medicine Pub Date : 2017-04-01 DOI: 10.5742/MEIM.2017.92935

A. Alyamany, N. Abdel-Aziz, Safaa A. A. Khaled

{"title":"Anthracycline versus Non-Anthracycline Induction Regimens in Patients with De Novo Acute Myeloid Leukemia","authors":"A. Alyamany, N. Abdel-Aziz, Safaa A. A. Khaled","doi":"10.5742/MEIM.2017.92935","DOIUrl":"https://doi.org/10.5742/MEIM.2017.92935","url":null,"abstract":"Background & Objectives: Acute myeloid leukemia (AML) is the most prevalent form of acute leukemias in adults; unfortunately it carries very poor prognosis. Over the past decade marvelous advances were achieved in understanding pathophysiology of AML and this was reflected in management of AML patients. Nevertheless the standard anthracycline based induction regimens remained the cornerstone for treatment of AML; however their effectiveness is limited by their well known cardiotoxicity. To our knowledge this is the first study that investigated anthracycline versus non-anthracycline induction regimens in patients with AML. Methods: 90AML patients were enrolled in the study; they were retrospectively recruited from AML patients who were admitted at South Egypt Cancer Institute (SECI) from 2000-2010. Demographic, clinical, hematologic and data concerning treatment and therapeutic response were collected from hospital records of patients. Results: Analysis of the collected data showed lower median age of the study participants compared to other studies, FAB M2, M3, M4, followed by M1 were the commonest FAB subtypes among the study patients. Survival analysis showed longer overall survival (OS) and progression free survival (PFS) in those treated with anthracycline induction regimens compared with the non-anthracycline treated group. Also, higher incidence of relapse was observed in the non-anthracycline group. Conclusion: Anthracycline based induction regimens are still more effective than non-anthracycline regimens for treatment of AML, however the search for safer drugs than anthracyclines is still mandatory.","PeriodicalId":243742,"journal":{"name":"Middle East Journal of Internal Medicine","volume":"18 3-4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121006266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diffuse Peritoneal Deciduosis in Pregnancy : A Case Report 妊娠期弥漫性腹膜蜕膜病1例报告

Middle East Journal of Internal Medicine Pub Date : 2017-04-01 DOI: 10.5742/MEIM.2017.92936

Nansi Al Fayez, B. Khreisat

引用次数: 0

Quadruplet Heterotopic Pregnancy : A Case Report 四胞胎异位妊娠1例报告

Middle East Journal of Internal Medicine Pub Date : 2017-04-01 DOI: 10.5742/MEIM.2017.92938

Rema Khlaif Omosh, I. Fayez, Nancy Dari Alfayez

{"title":"Quadruplet Heterotopic Pregnancy : A Case Report","authors":"Rema Khlaif Omosh, I. Fayez, Nancy Dari Alfayez","doi":"10.5742/MEIM.2017.92938","DOIUrl":"https://doi.org/10.5742/MEIM.2017.92938","url":null,"abstract":"Background: Heterotopic pregnancy is a condition in which pregnancy occurs synchronously intrauterine and extrauterine. The estimated incidence following spontaneous conception is below 1/30,000. On the other hand, the incidence in artificial reproductive techniques has been reported to be as high as 1/100. Case: This case report is of a 20 year old woman, nulliparous, who presented to the emergency department with acute abdominal pain post ovulation induction with human menopausal gonadotrophins and intrauterine insemination. Examination revealed acute surgical abdomen. Ultra-sonographic examination showed viable triplet intrauterine gestation of 10 weeks and presence of right complex adnexal mass. Laparotomy was done and the patient was found to have right tubal ectopic pregnancy that was managed by salpingostomy. Post operative period was uneventful and patient was discharged with viable three embryos and she was followed as an outpatient in a high risk pregnancy clinic. Comment: Though the incidence of heterotopic pregnancy is low following spontaneous pregnancy but a high index of suspicion must be considered in any patient with intrauterine pregnancy who presented with abdominal pain and adnexal mass and particularly if conception occurs after artificial reproductive techniques. This approach would avoid maternal morbidity and mortality.","PeriodicalId":243742,"journal":{"name":"Middle East Journal of Internal Medicine","volume":"641 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116086801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Obesity Management in Primary Health Care 初级卫生保健中的肥胖管理

Middle East Journal of Internal Medicine Pub Date : 2016-11-01 DOI: 10.5742/MEIM.2016.9290

A. Abyad

引用次数: 3

Acute Chest Syndrome Does Not Have a Chronic Inflammatory Background in Sickle Cell Diseases 急性胸综合征在镰状细胞病中没有慢性炎症背景

Middle East Journal of Internal Medicine Pub Date : 2016-08-01 DOI: 10.5742/MEIM.2016.92862

M. Helvaci, H. Sahan, N. Atçı

引用次数: 0

Splenomegaly in Patients with Sideropenic Anemias : Clinical and Hematologic Significance 铁缺乏性贫血患者脾肿大:临床和血液学意义

Middle East Journal of Internal Medicine Pub Date : 2016-08-01 DOI: 10.5742/MEIM.2016.92863

Safaa A. A. Khaled, G. Seifeldein

引用次数: 0

Update on the Use of Vitamin B12 in Management of Pain 使用维生素B12治疗疼痛的最新进展

Middle East Journal of Internal Medicine Pub Date : 2016-08-01 DOI: 10.5742/MEIM.2016.92864

A. Abyad

{"title":"Update on the Use of Vitamin B12 in Management of Pain","authors":"A. Abyad","doi":"10.5742/MEIM.2016.92864","DOIUrl":"https://doi.org/10.5742/MEIM.2016.92864","url":null,"abstract":"Methylcobalamin (MeCbl), the activated form of vitamin B12, has been used to manage some nutritional diseases and other diseases in the clinic, including Alzheimer’s disease and rheumatoid arthritis. As an adjuvant, it effects neuronal protection by fostering regeneration of injured nerves and alienating glutamate-induced neurotoxicity. Recently several studies revealed that MeCbl may have conceivable analgesic effects in experimental and clinical studies. It can reduce, pain behaviors in diabetic neuropathy, low back pain and neuralgia. MeCbl ameliorate nerve conduction, stimulated the regeneration of injured nerves, and inhibited ectopic spontaneous discharges of injured primary sensory neurons. Low back pain is an everyday problem worldwide. It can lead to a great financial burden to society due to absenteeism or having work limitations. Back pain is one of the most common symptoms for seeing primary care physicians and one of the top 5 causes of surgery. Recent studies have shown a correlation between vitamin B12 injection and a decrease in Low back pain. This review aims to synopsize the analgesic effect and mechanisms of MeCbl at the present with particular stress on chronic low back pain. Intramuscular vitamin B12 injections appear to be of benefit in the reduction of chronic low back pain and also improve associated disability. However, further research is necessary to study the possible long term adverse reactions of these intramuscular injections.","PeriodicalId":243742,"journal":{"name":"Middle East Journal of Internal Medicine","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126257523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effectiveness of an interventional program for the management of hypertension through strengthening of the health care delivery system : a pilot study 通过加强卫生保健服务系统管理高血压干预方案的有效性:一项试点研究

Middle East Journal of Internal Medicine Pub Date : 2016-08-01 DOI: 10.5742/MEIM.2016.92861

W. Qidwai, K. Kazmi, K. Nanji, Sana Anees

引用次数: 0