ER Bradley, HJ Petty, L. Tomlinson, SJ Paterson, S. Brij, BD Al-Sheklly, W. Khan
{"title":"P47 A pilot study for an asthma in pregnancy service within a UK tertiary centre","authors":"ER Bradley, HJ Petty, L. Tomlinson, SJ Paterson, S. Brij, BD Al-Sheklly, W. Khan","doi":"10.1136/thorax-2021-btsabstracts.157","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.157","url":null,"abstract":"","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125229324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Stewart-Kelcher, A. Patel, S. Rahman, A. Hearn, C. Roxas, L. Green, L. Thomson, M. Fernandes, A. Nanzer, D. Jackson, J. Dhariwal, G. d'Ancona
{"title":"P42 Asthma treatment adherence checks: present and future","authors":"N. Stewart-Kelcher, A. Patel, S. Rahman, A. Hearn, C. Roxas, L. Green, L. Thomson, M. Fernandes, A. Nanzer, D. Jackson, J. Dhariwal, G. d'Ancona","doi":"10.1136/thorax-2021-btsabstracts.152","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.152","url":null,"abstract":"","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124094326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Ricketts, R. Chaudhuri, F. Steffensen, J. Baker, D. Buchan, D. Cowan
{"title":"P50 Use of accelerometers to compare physical activity levels in participants with asthma grouped by body mass index and asthma severity","authors":"H. Ricketts, R. Chaudhuri, F. Steffensen, J. Baker, D. Buchan, D. Cowan","doi":"10.1136/thorax-2021-btsabstracts.160","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.160","url":null,"abstract":"Background: Patients with asthma may find it impacts their ability to be physically active. Physical activity (PA) has been demonstrated to be lower in asthmatics compared to healthy controls. Obesity is commonly linked with difficult-to-control asthma and can worsen outcomes. At least 150 minutes of moderate physical activity (PA) per week is recommended for all adults by the World Health Organisation. We aimed to compare PA levels in patients with difficult-to-control asthma and body mass index (BMI) ≥25 kg/m 2 (DOW group) and two control groups with mild-moderate asthma, one with BMI <25 kg/ m 2 (MHW group) and one with BMI ≥25 kg/m 2 (MOW group). Methods: This cross-sectional study used 7-day recordings from wrist-worn accelerometers to compare PA between groups. We recorded inactive time, light (LPA) and moderate-vigorous physical activity (MVPA). We also measured novel metrics: intensity gradient (IG) reflecting PA intensity, and average acceleration (AA) reflecting PA volume. Parameters were compared across groups using ANOVA testing for normally distributed data and Kruskall-Wallis for skewed data. Correlation analysis explored associations between PA parameters and asthma measures. As AA was most closely correlated with asthma measures, we compared the highest and lowest AA quartiles using unpaired t and Mann-Whitney U tests, depending on normality. Results: 75 participants were recruited, 25 per group. Inactive time was significantly higher (p<0.001), and LPA (p=0.007), MVPA (p<0.001), IG (p=0.0001) and AA (p<0.0001) all significantly lower in DOW group compared to MHW and MOW groups, even after adjusting for age and BMI. For AA, notable correlations included beclometasone diproprionate-equivalent dose of inhaled corticosteroid (r=-0.591, p<0.0001),","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121727242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Slinger, R. Slinger, K. Prior, A. Vyas, P. Mannion
{"title":"P51 Spot the difference? Comparison of clinical characteristics of patients with inducible laryngeal obstruction (ILO) and asthma referred to a severe asthma and airways tertiary centre","authors":"C. Slinger, R. Slinger, K. Prior, A. Vyas, P. Mannion","doi":"10.1136/thorax-2021-btsabstracts.161","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.161","url":null,"abstract":"P51 Table 1 Patient characistics according to diagnosis Poster sessions A94 Thorax 2021;76(Suppl 2):A1–A205 on N ovem er 2, 2021 by gest. P rocted by coright. httphorax.bm jcom / T hrax: frst pulished as 10.113orax-2021-B T S abscts.161 on 8 N ovem er 221. D ow nladed fom","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128465839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ZK Yusuf, D. Wensley, H. Owton, SJ Singh, Jacquelyn Allen-Collinson
{"title":"P43 Experiences of asthma in the UK-resident adult South Asian population: a qualitative study","authors":"ZK Yusuf, D. Wensley, H. Owton, SJ Singh, Jacquelyn Allen-Collinson","doi":"10.1136/thorax-2021-btsabstracts.153","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.153","url":null,"abstract":"","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134011637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Walters, F. Rezai, N. Le Moual, J. Marsh, A. Bahron, M. Krishna, A. Mansur
{"title":"P55 Occupations, workplace exposures and physical demands of work in patients with severe asthma","authors":"G. Walters, F. Rezai, N. Le Moual, J. Marsh, A. Bahron, M. Krishna, A. Mansur","doi":"10.1136/thorax-2021-btsabstracts.165","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.165","url":null,"abstract":"","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132447885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Walters, J. Marsh, A. Bahron, M. Krishna, A. Mansur
{"title":"P45 Associations between employment and socio-demographic and health-related factors, in patients with severe asthma","authors":"G. Walters, J. Marsh, A. Bahron, M. Krishna, A. Mansur","doi":"10.1136/thorax-2021-btsabstracts.155","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.155","url":null,"abstract":"","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129503779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Pavord, M. Wechsler, L. Ford, J. Maspero, D. Langton, C. Domingo, A. Papi, A. Bourdin, H. Watz, X. Mao, N. Amin, M. Hardin, Y. Zhang, Ah Khan
{"title":"P48 Long-term efficacy of dupilumab in patients with moderate-to-severe asthma in the LIBERTY ASTHMA TRAVERSE open-label extension study: improvements in asthma control and health-related quality of life","authors":"I. Pavord, M. Wechsler, L. Ford, J. Maspero, D. Langton, C. Domingo, A. Papi, A. Bourdin, H. Watz, X. Mao, N. Amin, M. Hardin, Y. Zhang, Ah Khan","doi":"10.1136/thorax-2021-btsabstracts.158","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.158","url":null,"abstract":"","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130225841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Hisinger-Molkanen, P. Pallasaho, A. Sovijarvi, L. Tuomisto, H. Andersén, A. Lindqvist, H. Backman, A. Langhammer, E. Ronmark, B. Lundback, P. Ilmarinen, H. Kankaanranta, P. Piirila
{"title":"P54 Combined exposure to vapors, gases, dusts, fumes and tobacco smoke increases the risk of asthma symptoms","authors":"H. Hisinger-Molkanen, P. Pallasaho, A. Sovijarvi, L. Tuomisto, H. Andersén, A. Lindqvist, H. Backman, A. Langhammer, E. Ronmark, B. Lundback, P. Ilmarinen, H. Kankaanranta, P. Piirila","doi":"10.1136/thorax-2021-btsabstracts.164","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.164","url":null,"abstract":"P55 Figure 1 Poster sessions A96 Thorax 2021;76(Suppl 2):A1–A205 on N ovem er 1, 2021 by gest. P rocted by coright. httphorax.bm jcom / T hrax: frst pulished as 10.113orax-2021-B T S abscts.165 on 8 N ovem er 221. D ow nladed fom major comorbidity=204 (37), median%predicted FEV1=80 (58–96). The most frequently identified occupations were: office administrator=48 (10), nurse=43 (9), care assistant (personal or institutional) =34 (7), teacher=21 (4), teaching assistant=18 (4). Using OASJEM 186/504 (37) patients may be exposed to 1 respiratory sensitizer or airway irritant, and 140/504 (28) to both categories. Physical demand of work was categorised as follows: sedentary=186/504 (37), light=220 (44), medium=88 (17), heavy=10 (2). Patients employed in medium or heavy physical work had median% FEV1/FVC=66 (52–79), median%predicted FEV1=75 (50–96), and median ACQ7score=2.9 (2.0–3.7). Conclusion Clinicians should enquire about, and exclude, work-related inhalational exposures that may cause or exacerbate symptoms in patients with severe asthma. Clinicians should also be aware of unrecognized work disability, since many patients are employed in physically demanding roles, despite the presence of airflow obstruction and poor asthma control. REFERENCES 1. Le Moual N, et al. Occup Environ Med. 2018;75(7):507–14. 2. Miller AR, et al. Work, Jobs, and Occupations: A Critical Review of the Dictionary of Occupational Titles. Washington DC: National Academy Press, 1980. Cough: is it a problem and what can we do about it? P56 CHRONIC COUGH IN GERMANY: PREVALENCE AND PATIENT CHARACTERISTICS JC Virchow, E Fonseca, H Salmen, VW Li, A Martin, JE Brady, J Schelfhout. University of Rostock Medical Clinic, Rostock, Germany; Merck and Co., Inc., Kenilworth, USA; MSD Sharp and Dohme GmbH, Haar, Germany; Kantar Health Co., Inc., New York,","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"404 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115992428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Haines, J. Wingfield Digby, J. King, J. Smith, S. Fowler
{"title":"P52 A systematic review of the effectiveness of existing non-pharmacological interventions used to treat adults with inducible laryngeal obstruction","authors":"J. Haines, J. Wingfield Digby, J. King, J. Smith, S. Fowler","doi":"10.1136/thorax-2021-btsabstracts.162","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.162","url":null,"abstract":"","PeriodicalId":243447,"journal":{"name":"Diagnostics and monitoring of asthma and co-morbidities","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125415006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}