Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova最新文献

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[Experience of staged and simultaneous bilateral thalamotomy using MR-guided focused ultrasound in the treatment of essential tremor]. [核磁共振引导下聚焦超声分阶段同步双侧丘脑切开术治疗特发性震颤的经验]。
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Pub Date : 2023-01-01 DOI: 10.17116/jnevro202312307165
D I Nabiullina, R M Galimova, S N Illarioshkin, I V Buzaev, Sh M Safin, G N Akhmadeeva, N R Mukhamadeeva, D K Krekotin
{"title":"[Experience of staged and simultaneous bilateral thalamotomy using MR-guided focused ultrasound in the treatment of essential tremor].","authors":"D I Nabiullina,&nbsp;R M Galimova,&nbsp;S N Illarioshkin,&nbsp;I V Buzaev,&nbsp;Sh M Safin,&nbsp;G N Akhmadeeva,&nbsp;N R Mukhamadeeva,&nbsp;D K Krekotin","doi":"10.17116/jnevro202312307165","DOIUrl":"https://doi.org/10.17116/jnevro202312307165","url":null,"abstract":"<p><strong>Objective: </strong>To show that effective and safe bilateral MR-guided focused ultrasound (MRgFUS) treatment of essential tremor (ET) is achievable.</p><p><strong>Material and methods: </strong>Four male patients underwent bilateral thalamotomy. Two patients underwent staged thalamotomy, with the ≥12 month interval between operations. Two patients underwent simultaneous bilateral thalamotomy.</p><p><strong>Results: </strong>After six months, all patients noted a significant reduction in symptoms on both sides: when assessing tremors with the Clinical Rating Scale for Tremor, the severity of hyperkinesis decreased by 57.5-69.7%. We did not observe any complications in any of the cases.</p><p><strong>Conclusion: </strong>Our experience indicates that simultaneous bilateral MRI-guided focused ultrasound treatment of ET can be performed safely and effectively. Further research is necessary to estimate the effectiveness and adverse effect rates.</p>","PeriodicalId":24030,"journal":{"name":"Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9872265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Treatment of cognitive, behavioral and mental disorders in patients with vascular dementia: results of a multicenter, randomized, double-blind, placebo-controlled clinical trial]. [血管性痴呆患者认知、行为和精神障碍的治疗:一项多中心、随机、双盲、安慰剂对照临床试验的结果]。
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Pub Date : 2023-01-01 DOI: 10.17116/jnevro202312307141
O N Tkacheva, E A Mkhitaryan, I V Kolykhalov, A N Belova, O V Kolokolov, L G Zaslavsky, N M Khasanova, L R Akhmadeeva, E I Bogdanov
{"title":"[Treatment of cognitive, behavioral and mental disorders in patients with vascular dementia: results of a multicenter, randomized, double-blind, placebo-controlled clinical trial].","authors":"O N Tkacheva,&nbsp;E A Mkhitaryan,&nbsp;I V Kolykhalov,&nbsp;A N Belova,&nbsp;O V Kolokolov,&nbsp;L G Zaslavsky,&nbsp;N M Khasanova,&nbsp;L R Akhmadeeva,&nbsp;E I Bogdanov","doi":"10.17116/jnevro202312307141","DOIUrl":"https://doi.org/10.17116/jnevro202312307141","url":null,"abstract":"<p><strong>Objective: </strong>Evaluation of the efficacy and safety of Prospect in the treatment of cognitive, behavioral and mental disorders in patients with vascular dementia (VSD).</p><p><strong>Material and methods: </strong>In a double-blind, placebo-controlled, parallel-group randomised clinical trial, 406 patients aged 60-85 years old with a diagnosis of mild/moderate vascular dementia (10-24 on the Mini-Mental State Examination (MMSE)) and without signs of depression (Cornell Scale for Depression in Dementia (CSDD) scores ≤10) were included. At Visit 1, complaints and medical history were collected, vital signs were recorded, cognitive impairment was assessed using MMSE and MoCA, NPI-C and CSDD were completed, and an MRI brain scan was performed. Patients were randomised into two groups: patients in group 1 received Prospekta in a dosage of 2 tablets two times a day for 24 weeks, and patients in group 2 received Placebo according to the study drug regimen.</p><p><strong>Results: </strong>Patients in both groups had no differences in demographic and baseline clinical characteristics. Administration of Prospekta for 24 weeks reduced cognitive impairment in patients with vascular dementia compared to the placebo group. The mean MoCA score increased from 17.0±3.6 [17.1±3.6] to 20.5±4.7 [20.4±4.7] in patients treated with Prospekta, whereas it increased from 17.3±3.7 [17.3±3.8] to 19.2±4.9 [19.2±5.0] in the Placebo group. Treatment with the medication also reduced the severity of neuropsychiatric symptoms as measured by the NPI-C scale. The mean score on this scale decreased from 57.0±26.7 [56.7±25.4] to 39.8±23.6 [39.8±23.5] in the Prospekta group and from 55.5±25.5 [55.3±24.4] to 42.8±27.6 [42.3±25.3] in the Placebo group. The difference in mean MoCA and NPI-C scores between the Prospekta and Placebo groups was statistically significant.</p><p><strong>Conclusion: </strong>Prospekta is an effective and safe drug for treating cognitive, behavioural and mental disturbances in patients with vascular dementia.</p>","PeriodicalId":24030,"journal":{"name":"Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9872267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
[An effect of antipsychotic and anticholinergic treatment on cognitive function in patients with schizophrenia]. [抗精神病和抗胆碱能治疗对精神分裂症患者认知功能的影响]。
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Pub Date : 2023-01-01 DOI: 10.17116/jnevro202312307180
M A Tumova, A A Stepanova, Y S Zazulina, Z T Guseinova, M M Zaitseva, I V Dyment, A P Kotsyubinsky, M V Ivanov
{"title":"[An effect of antipsychotic and anticholinergic treatment on cognitive function in patients with schizophrenia].","authors":"M A Tumova,&nbsp;A A Stepanova,&nbsp;Y S Zazulina,&nbsp;Z T Guseinova,&nbsp;M M Zaitseva,&nbsp;I V Dyment,&nbsp;A P Kotsyubinsky,&nbsp;M V Ivanov","doi":"10.17116/jnevro202312307180","DOIUrl":"https://doi.org/10.17116/jnevro202312307180","url":null,"abstract":"<p><strong>Objective: </strong>To reveal the relationships between antipsychotic and anticholinergic drugs and cognitive functions in patients with schizophrenia.</p><p><strong>Material and methods: </strong>The observational prospective study was conducted at the Bekhterev National Medical Center of Psychiatry and Neurology. The study involved 41 patients (22 men and 19 women) with paranoid schizophrenia, according to ICD 10 criteria, aged 30.12±8.24 years on stable antipsychotic monotherapy or in combination with anticholinergic drug (trihexiphenidyl). Cognitive functions were assessed using the «Brief Assessment of Cognitive Function in Patients with Schizophrenia» (BACS) scale, severity of mental state and extrapyramidal disturbances were measured using the «Positive and Negative Syndrome Scale (PANSS) and the Simpson-Angus Scale for Assessment of Extrapyramidal Side Effects (SAS). All examination procedures were performed twice at weeks 2 and 8 of therapy. Patients were divided into 2 groups according to the type of antipsychotic therapy. Twelve patients received first generation antipsychotics (FGAs) (group 1), 29 patients received second generation antipsychotics (SGAs) (group 2).</p><p><strong>Results: </strong>Patients receiving SGAs had a significant decrease in the overall SAS score at week 8 of therapy compared with data at week 2, and there was an improvement in cognitive function, unlike patients receiving FGAs. There were also changes on BACS tests the digit sequencing (V=51.5, <i>p</i>=0.007), token motor task (V=75.5, <i>p</i>=0.007) and Tower of London (V=52, <i>p</i>=0.027) only in patients of group 2.</p><p><strong>Conclusion: </strong>The improved tolerance to the drug, as well as cognitive measures, was shown in patients taking SGAs by week 8. Our study confirms the importance of adhering to the minimum effective dose of antipsychotic drugs for the treatment of schizophrenia to prevent cognitive impairment, and to give preference to SGAs in the choice of treatment.</p>","PeriodicalId":24030,"journal":{"name":"Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9885939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Neuropathic pain caused by the toxic effect of chemotherapy in patients with malignant neoplasms]. 【恶性肿瘤患者化疗毒性作用引起的神经性疼痛】。
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Pub Date : 2023-01-01 DOI: 10.17116/jnevro20231230517
S V Chubykina, M U Tatarinova, G G Avakyan
{"title":"[Neuropathic pain caused by the toxic effect of chemotherapy in patients with malignant neoplasms].","authors":"S V Chubykina,&nbsp;M U Tatarinova,&nbsp;G G Avakyan","doi":"10.17116/jnevro20231230517","DOIUrl":"https://doi.org/10.17116/jnevro20231230517","url":null,"abstract":"<p><p>This article discusses chemotherapy-induced peripheral neuropathic pain (CIPNP) and its associated neuropathic pain syndrome that occurs in patients with malignant neoplasms (MN) during cytostatic therapy. The overall prevalence of CIPNP in patients with malignant neoplasms associated with chemotherapy with neurotoxic drugs is estimated, according to various sources, to be about 70%. The pathophysiological mechanisms of CIPNP have not been fully studied, but it is known that they are based on: impaired axonal transport, oxidative stress, induction of apoptosis, DNA damage, dysfunction of voltage-gated ion channels, and central mechanisms. It is important to recognize CIPNP in the clinical symptoms of patients with cancer treated with cytostatics, since these disorders can lead to serious restrictions in the motor, sensory and autonomic functions of the upper and lower extremities, as well as reduce the quality of life and daily functioning of such patients, forcing them to adjust the dose of chemotherapy drugs, transfer the next cycles and even interrupt the treatment of cancer carried out according to vital needs. In addition to the clinical examination, scales and questionnaires have been developed to identify symptoms of CIPNP, but it is most important for neurological and oncological specialists to know and be able to recognize such symptoms in patients. The mandatory research methods for identifying the symptoms of polyneuropathy include electroneuromyography (ENMG), which allows you to assess muscle activity, functional characteristics and the state of the function of peripheral nerves. The methods used to reduce symptoms are screening patients for the development of CIPNP and identifying patients at high risk of CIPNP and, if necessary, reducing the dose or changing cytostatics. Methods for correcting this disorder using different classes of drugs require more detailed study and further research.</p>","PeriodicalId":24030,"journal":{"name":"Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9995051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The use of the Mini-Cog, MMSE, and GPCOG tests in domestic clinical practice for the evaluation of cognitive disorders in elderly and senile patients: the results of a survey of experts' opinions]. [Mini-Cog、MMSE、GPCOG测试在国内临床评价中老年患者认知障碍的应用:专家意见调查结果]。
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Pub Date : 2023-01-01 DOI: 10.17116/jnevro202312307155
T I Ionova, E V Frolova, K V Ovakimyan, E A Mkhitaryan, O N Tkacheva, D L Logunov, A Yu Oskova, E A Vasileva, Yu V Zhitkova, A A Gasparyan, K V Lunev, E A Luneva, N M Porfirieva, T P Nikitina
{"title":"[The use of the Mini-Cog, MMSE, and GPCOG tests in domestic clinical practice for the evaluation of cognitive disorders in elderly and senile patients: the results of a survey of experts' opinions].","authors":"T I Ionova,&nbsp;E V Frolova,&nbsp;K V Ovakimyan,&nbsp;E A Mkhitaryan,&nbsp;O N Tkacheva,&nbsp;D L Logunov,&nbsp;A Yu Oskova,&nbsp;E A Vasileva,&nbsp;Yu V Zhitkova,&nbsp;A A Gasparyan,&nbsp;K V Lunev,&nbsp;E A Luneva,&nbsp;N M Porfirieva,&nbsp;T P Nikitina","doi":"10.17116/jnevro202312307155","DOIUrl":"https://doi.org/10.17116/jnevro202312307155","url":null,"abstract":"<p><strong>Objective: </strong>To explore the experts' opinion on the feasibility of using Mini-Kog, MMSE and GPCOG tests for screening assessment of cognitive impairment in elderly and senile patients at the primary stage of medical care, as well as to compare different characteristics of these tests according to experts' opinion.</p><p><strong>Material and methods: </strong>The survey of specialists was carried out on the basis of 6 Medical Centers. Prior to the survey, specialists tested cognitive functions in elderly and senile patients during routine visits undergoing routine admission using Mini-Kog, MMSE and GPCOG tests, as well as interviewed their relatives using the corresponding section of the GPCOG. During the survey, specialists filled out a special physician checklist containing items for indicating socio-demographic information and questions regarding the use of tests for assessing cognitive functions in elderly and senile patients in daily clinical practice.</p><p><strong>Results: </strong>The survey involved 40 specialists from different cities of Russia (mean age±SD - 38.6±14.3 years, 82.5% - women). Elderly and senile patients accounted for the predominant proportion (76-100%) of all followed-up patients. All physicians considered it important to conduct a cognitive assessment in elderly patients and they have to use various cognitive tests in their practice. According to most experts, among the Mini-Kog, MMSE and GPCOG tests, all three tools are informative, convenient and suitable for screening cognitive impairment in geriatric patients. The MMSE test is more informative and convenient. Mini-Kog, compared to the other two tools, is the simplest and most time-efficient tool that is also better perceived by patients. An advantage of the GPCOG is the possibility of participation of informants in the assessment of cognitive functions in older patients.</p><p><strong>Conclusion: </strong>The findings could be used in further research focused on improving the approaches for early detection of cognitive impairment in geriatric patients by primary care physicians.</p>","PeriodicalId":24030,"journal":{"name":"Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10379497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
[Slow-wave sleep and the possibilities of modern insomnia therapy]. [慢波睡眠和现代失眠疗法的可能性]。
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Pub Date : 2023-01-01 DOI: 10.17116/jnevro202312308149
V E Medvedev, N V Titova, I V Milyukhina, F Sh Shagiakhmetov, R R Borukaev, I V Kolyvanova
{"title":"[Slow-wave sleep and the possibilities of modern insomnia therapy].","authors":"V E Medvedev,&nbsp;N V Titova,&nbsp;I V Milyukhina,&nbsp;F Sh Shagiakhmetov,&nbsp;R R Borukaev,&nbsp;I V Kolyvanova","doi":"10.17116/jnevro202312308149","DOIUrl":"https://doi.org/10.17116/jnevro202312308149","url":null,"abstract":"<p><p>Effective therapy of insomnia, especially chronic insomnia, is one of the most pressing neuropsychiatric problems. Unfortunately, at present in the Russian Federation, as in most other countries of the world, there are no officially approved drugs for long-term treatment of insomnia. In this regard, the use of medical sedation agents that do not have restrictions on the duration of use is of considerable interest. This review considers drugs of various psychopharmacological classes, one way or another used in practice for the correction of sleep disorders, especially in patients with underlying comorbid pathology.</p>","PeriodicalId":24030,"journal":{"name":"Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10517872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Piecewise linear regression model of hemostasis dynamics in donors and patients with schizophrenia]. 献血者与精神分裂症患者止血动态的分段线性回归模型
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Pub Date : 2023-01-01 DOI: 10.17116/jnevro2023123011111
O V Senko, O S Brusov, L I Ponomareva, I A Matveev, N S Karpova, A V Kuznetsova, M Yu Salmanov
{"title":"[Piecewise linear regression model of hemostasis dynamics in donors and patients with schizophrenia].","authors":"O V Senko,&nbsp;O S Brusov,&nbsp;L I Ponomareva,&nbsp;I A Matveev,&nbsp;N S Karpova,&nbsp;A V Kuznetsova,&nbsp;M Yu Salmanov","doi":"10.17116/jnevro2023123011111","DOIUrl":"https://doi.org/10.17116/jnevro2023123011111","url":null,"abstract":"<p><strong>Objective: </strong>This work is to develop and use a new approach to the analysis of differences between the velocity profiles of registered light signals in groups of patients with schizophrenia and healthy donors.</p><p><strong>Material and methods: </strong>The present study involved 62 patients (all female) with schizophrenia or schizoaffective disorders in the acute period (observational study - 2016-2017). 44 patients were diagnosed with paranoid schizophrenia with an attack-progredient type of course (F20.01 according to ICD-10) or with a continuous type of course (F20.02). The fibrinodynamics test (FD) was performed on the T-2 thrombodynamics device (Hemacore LLC, Moscow), which makes it possible to monitor the processes of coagulation and fibrinolysis in the cuvette channels filled with fresh blood plasma. The result of the test are the brightness profiles of the clot.</p><p><strong>Results: </strong>In the proposed approach, each profile is characterized by a vector of distances between it and other analyzed profiles. At that the distances between the profiles are calculated as the sum of the modules of differences at different points of the observation interval. This method makes it possible to overcome a certain loss of information that occurs when using a standard method based on the calculation of several parameters that characterize the analyzed velocity profiles. The method includes the construction of all kinds of statistically significant piecewise linear regression models that link the distances to two profiles. The velocity profiles corresponding to the points lying on opposite sides of the break point of such models have significantly different shapes. In practice, it turns out that for many piecewise linear regression models, the break points also significantly separate the velocity profiles for the compared groups of donors and patients with schizophrenia. Statistically significant deviations at the level <i>p</i>≤0.01 exist for 16.1% of 3143 statistically significant piecewise linear models.</p><p><strong>Conclusion: </strong>The developed method makes it possible to visually establish the relationship between the shape of the velocity profile and the presence of the disease.</p>","PeriodicalId":24030,"journal":{"name":"Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10583685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Gut microbiota in patients with relapsing-remitting multiple sclerosis]. [复发缓解型多发性硬化症患者的肠道微生物群]。
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Pub Date : 2023-01-01 DOI: 10.17116/jnevro20231230118
M V Tardov, Sh Talapbek, N V Sturov, E V Popova, A V Boldin, E I Rusanova, N N Suvorova
{"title":"[Gut microbiota in patients with relapsing-remitting multiple sclerosis].","authors":"M V Tardov,&nbsp;Sh Talapbek,&nbsp;N V Sturov,&nbsp;E V Popova,&nbsp;A V Boldin,&nbsp;E I Rusanova,&nbsp;N N Suvorova","doi":"10.17116/jnevro20231230118","DOIUrl":"https://doi.org/10.17116/jnevro20231230118","url":null,"abstract":"<p><p>Microorganisms in human life play a huge role: in particular, those that coexist with the host organism, inhabiting the skin, upper respiratory tract, external genitalia and especially the digestive tract. The intestinal microbiota, including bacteriome, mycobiome and virome, not only takes part in the digestion process, but also provides the synthesis of a number of vitamins. The intestinal microbiome also serves as the basis for a system of extensive bidirectional neuroendocrine pathways that connect microbiota with various regions of the central nervous system, the hypothalamic-pituitary-adrenal system, and the peripheral parts of the autonomic nervous system. This system of connections has got the name of gut-brain axis and has attracted close attention of scientists over the past two decades, since a targeted impact on the intestinal flora is potentially capable of changing the nature of nervous system regulatory influences on the whole body. It is especially important to study patterns of functioning of the gut-brain axis in patients with the nervous system pathology, namely neurodegenerative and demyelinating diseases. Methods for their treatment continue to improve, and perhaps the correction of the gut microbiotic composition will serve as an additional therapeutic approach. The review article describes current views on the role of the intestinal microbiota, provides the latest data on the composition of bacteriome, mycobiome, and virome in patients with relapsing-remitting multiple sclerosis.</p>","PeriodicalId":24030,"journal":{"name":"Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10590412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
[Insomnia in neurological patients with disabilities]. [神经系统残疾患者的失眠]。
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Pub Date : 2023-01-01 DOI: 10.17116/jnevro202312302112
E A Korabelnikova, A N Akavov, M L Baranov
{"title":"[Insomnia in neurological patients with disabilities].","authors":"E A Korabelnikova,&nbsp;A N Akavov,&nbsp;M L Baranov","doi":"10.17116/jnevro202312302112","DOIUrl":"https://doi.org/10.17116/jnevro202312302112","url":null,"abstract":"<p><p>Sleep is the most important factor reflecting the level of psychophysical well-being of a person and influencing him/her to the same extent. The greater susceptibility to sleep disturbances in patients with disabilities is associated with numerous factors. In the existing literature, there are few studies of insomnia in people with neurological disabilities. This article presents a current view on sleep disorders in disabled people and methods for their treatment.</p>","PeriodicalId":24030,"journal":{"name":"Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10791416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Comparison of psychometric and pathopsychological approaches in the assessment of intellectual activity in children and adolescents with progressive forms of schizophrenia]. [心理测量法和病理心理学方法在评估儿童和青少年进行性精神分裂症智力活动中的比较]。
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Pub Date : 2023-01-01 DOI: 10.17116/jnevro2023123021120
S E Strogova, N V Zvereva, A I Khromov, N V Simashkova
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