中华胃肠外科杂志最新文献

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[Neuro-immune interactions in the tumor microenvironment: from mechanisms to precision therapy]. 肿瘤微环境中的神经免疫相互作用:从机制到精确治疗。
中华胃肠外科杂志 Pub Date : 2025-09-25 DOI: 10.3760/cma.j.cn441530-20250826-00318
Y J Zhang, T P Luo, F L Liu
{"title":"[Neuro-immune interactions in the tumor microenvironment: from mechanisms to precision therapy].","authors":"Y J Zhang, T P Luo, F L Liu","doi":"10.3760/cma.j.cn441530-20250826-00318","DOIUrl":"10.3760/cma.j.cn441530-20250826-00318","url":null,"abstract":"<p><p>The nervous system, as the core hub of physiological regulation in the human body, plays a key role in the tumor microenvironment through the neuro-immune-tumor axis. Studies have shown that tumor-infiltrating nerve fibers regulate immune cell functions by releasing neurotransmitters, while immune cells can feedback and modulate neuronal activity, forming a dynamic bidirectional interaction network. The emerging field of cancer neuroimmunology focuses on the complex dialogue mechanisms between the nervous and immune systems in the tumor microenvironment. In-depth analysis of the neuro-immune interaction network not only provides new perspectives for understanding tumor immune escape, but also lays the theoretical foundation for developing novel combination therapies targeting the neuro-immune axis, potentially providing breakthrough strategies to overcome resistance to current immunotherapies.</p>","PeriodicalId":23959,"journal":{"name":"中华胃肠外科杂志","volume":"28 9","pages":"1080-1086"},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Rethinking lymph node dissection in gastric cancer during the era of immunotherapy]. 免疫治疗时代胃癌淋巴结清扫的再思考
中华胃肠外科杂志 Pub Date : 2025-09-25 DOI: 10.3760/cma.j.cn441530-20250626-00242
J Chen, Y J Wu, F L Liu
{"title":"[Rethinking lymph node dissection in gastric cancer during the era of immunotherapy].","authors":"J Chen, Y J Wu, F L Liu","doi":"10.3760/cma.j.cn441530-20250626-00242","DOIUrl":"10.3760/cma.j.cn441530-20250626-00242","url":null,"abstract":"<p><p>The rapid development of immunotherapy has changed the treatment pattern of gastric cancer surgery, constantly advancing from the battlefield of advanced gastric cancer treatment to neoadjuvant therapy. The combination of immunotherapy and chemotherapy has become a new trend in the treatment of locally advanced gastric cancer. This change has prompted us to re-examine the concept of traditional radical surgery for gastric cancer, especially for lymph node dissection, it presents new challenges. As the core site of immune response, lymph node dissection strategy has become one of the key factors affecting the overall efficacy of gastric cancer, and it urgently needs to be re optimized and evaluated in the wave of immunotherapy. Thus, a more precise and personalized new paradigm for radical gastric cancer surgery can be established, ultimately achieving multiple improvements in short-term and long-term efficacy, as well as quality of life.</p>","PeriodicalId":23959,"journal":{"name":"中华胃肠外科杂志","volume":"28 9","pages":"960-963"},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Visualizing the evidence of robotic gastrointestinal surgery based on guideline recommendations: an evidence mapping study of gastric and colorectal cancer]. [基于指南建议的机器人胃肠手术证据可视化:胃癌和结直肠癌的证据图谱研究]。
中华胃肠外科杂志 Pub Date : 2025-08-25 DOI: 10.3760/cma.j.cn441530-20250619-00229
Q Wang, M M Niu, R S Li, S Q Wang, Galyna Shabat, Alberto Aiolfi, J H Tian, K W Jiang, X N Liu, Luigi Bonavina
{"title":"[Visualizing the evidence of robotic gastrointestinal surgery based on guideline recommendations: an evidence mapping study of gastric and colorectal cancer].","authors":"Q Wang, M M Niu, R S Li, S Q Wang, Galyna Shabat, Alberto Aiolfi, J H Tian, K W Jiang, X N Liu, Luigi Bonavina","doi":"10.3760/cma.j.cn441530-20250619-00229","DOIUrl":"https://doi.org/10.3760/cma.j.cn441530-20250619-00229","url":null,"abstract":"<p><p>Robotic surgery, as an increasingly widespread application in the treatment of gastric and colorectal cancer, still faces obvious discrepancies in recommendations, indications, and evidence strength across existing guidelines. This study systematically analyzed 31 relevant guidelines and consensus statements (retrieved from Chinese and English databases from January 2010 to May 2025) from two dimensions: feasibility (effectiveness, safety, etc.) and training quality control.The results showed that colorectal cancer guidelines had a higher proportion (4 guidelines) of \"clear recommendations\" for robotic surgery, while gastric cancer guidelines predominantly presented \"conditional recommendations\" or no recommendations. In the training and quality control dimension, although structured suggestions received positive recommendations, more than half were based on low or very low-quality evidence. Evidence mapping indicated insufficient matching between \"case-specific recommendations\" and evidence grades in the feasibility dimension, while training processes emphasized the importance of standardized systems and team collaboration.The study highlights the existing heterogeneity in evidence-based guidelines for robotic gastrointestinal surgery, with colorectal cancer demonstrating a more mature evidence base and gastric cancer showing notable evidence gaps. It is recommended that future guideline development should strengthen the consistency between recommendation grades and evidence levels, promote high-quality research in upper gastrointestinal surgery, and improve surgeon training and certification systems to facilitate standardized clinical translation of robotic gastrointestinal surgery.</p>","PeriodicalId":23959,"journal":{"name":"中华胃肠外科杂志","volume":"28 8","pages":"927-936"},"PeriodicalIF":0.0,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Guideline for diagnosis and comprehensive treatment of colorectal liver metastases (version 2025)]. 【结直肠癌肝转移诊断与综合治疗指南(2025版)】。
中华胃肠外科杂志 Pub Date : 2025-08-25 DOI: 10.3760/cma.j.cn441530-20250713-00265
{"title":"[Guideline for diagnosis and comprehensive treatment of colorectal liver metastases (version 2025)].","authors":"","doi":"10.3760/cma.j.cn441530-20250713-00265","DOIUrl":"https://doi.org/10.3760/cma.j.cn441530-20250713-00265","url":null,"abstract":"<p><p>The liver is the main target organ for hematogenous metastases from colorectal cancer, and colorectal liver metastasis is one of the most difficult and challenging situations in the treatment. In order to improve the diagnosis and comprehensive treatment in China, the Guidelines have been edited and revised for seven times since 2008, including the overall evaluation, personalized treatment goals and comprehensive treatments, to prevent the occurrence of liver metastases, increase the local damage rate of liver metastases, prolong long-term survival, and improve quality of life. The revised Guideline version 2025 includes the diagnosis and follow-up, prevention, multidisciplinary team (MDT), surgery and local ablative treatment, neoadjuvant and adjuvant therapy, comprehensive treatment. The revised Guideline emphasizes precision treatment based on genetic molecular typing, especially recommending immune checkpoint inhibitors for dMMR/MSI-H patients, and enriched local treatment methods, such as liver transplantation, yttrium-90 microsphere selective internal radiotherapy, etc. The revised Guideline includes state-of-the-art experience and findings, detailed content, and strong operability.</p>","PeriodicalId":23959,"journal":{"name":"中华胃肠外科杂志","volume":"28 8","pages":"815-831"},"PeriodicalIF":0.0,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Deepguide for membrane anatomy navigation: the establishment and clinical application]. 【膜解剖导航深度导航仪的建立及临床应用】。
中华胃肠外科杂志 Pub Date : 2025-08-25 DOI: 10.3760/cma.j.cn441530-20250609-00217
Z H Chen, H B Wei
{"title":"[Deepguide for membrane anatomy navigation: the establishment and clinical application].","authors":"Z H Chen, H B Wei","doi":"10.3760/cma.j.cn441530-20250609-00217","DOIUrl":"https://doi.org/10.3760/cma.j.cn441530-20250609-00217","url":null,"abstract":"<p><p>In recent years, the concept of membrane anatomy has gain continuous extension and breakthrough in multiple specialized fields such as gastrointestinal surgery. Compared with traditional surgery, radical resection of gastrointestinal tumors based on the concept of membrane anatomy has shown significant advantages in therapeutic effects. However, in practical application, this concept still faces many problems and challenges, among which how to accurately identify membrane structures and achieve effective membrane navigation during surgery has become a key concern. To address the above issues, our team developed and established the Deepguide membrane navigation system, aiming to overcome the difficulties in membrane identification and navigation, and solve the critical problem of insufficient membrane integrity rate after gastrointestinal tumor surgery. This paper systematically reviews the creation process and clinical application scenarios of the Deepguide membrane navigation system, and prospects its future application prospects and development directions, to provide a useful reference for the development of membrane anatomy surgery and the research and development of navigation technologies.</p>","PeriodicalId":23959,"journal":{"name":"中华胃肠外科杂志","volume":"28 8","pages":"881-885"},"PeriodicalIF":0.0,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Application of right-opening single flap valvuloplasty based on tubular stomach in gastrointestinal reconstruction after laparoscopic proximal gastrectomy]. [基于管状胃的右开瓣瓣成形术在腹腔镜胃近端切除术后胃肠重建中的应用]。
中华胃肠外科杂志 Pub Date : 2025-08-25 DOI: 10.3760/cma.j.cn441530-20241030-00357
C Yu, W P Ji, D J Jiang, X L Chen, S Liu, W Z Chen, X J Ruan, J Qian, H Lu, J Y Yan
{"title":"[Application of right-opening single flap valvuloplasty based on tubular stomach in gastrointestinal reconstruction after laparoscopic proximal gastrectomy].","authors":"C Yu, W P Ji, D J Jiang, X L Chen, S Liu, W Z Chen, X J Ruan, J Qian, H Lu, J Y Yan","doi":"10.3760/cma.j.cn441530-20241030-00357","DOIUrl":"10.3760/cma.j.cn441530-20241030-00357","url":null,"abstract":"<p><p><b>Objective:</b> To explore the application value of right-opening single flap valvuloplasty based on tubular stomach in gastrointestinal reconstruction after laparoscopic proximal gastrectomy. <b>Method:</b> Use a linear cutting stapler to make a parallel curve from the angle of the stomach to the junction of the gastric fundus to remove the lesser curvature of the stomach, and detach the gastric body about 5 cm away from the tumor to create a tubular stomach. Use a marker pen to draw a C-shaped seromuscular flap area with a width of 2.5 cm and a height of 3.5 cm 1.5 cm below the residual stomach closure nail, and create a free muscle flap in the gap between the plasma muscle layer and the submucosal layer. Make a transverse incision of 3 cm at the lower edge of the mucosal bed, and intermittently suture the entire lower edge of the gastric wall with 3 stitches. Under laparoscopy, use 4-0 barbed wire to suture the 1 cm wide muscular layer at the top of the tubular stomach and the posterior wall of the esophagus about 5 cm away from the esophageal stump with 3 stitches. Push the upper end of the tubular stomach into the mediastinum, and then tighten the barbed wire to ensure a tight fit between the stomach and the posterior wall of the esophagus. Use an ultrasonic scalpel to remove the esophageal stump, suture the entire posterior wall of the esophagus with the gastric mucosa, and use barbed wire to suture the anterior wall from left to right. The anastomotic site is completely covered with a free muscle flap, and the barbed line is used to continuously suture the muscle flap along the C-shaped line to the gastric pulp muscle layer at the edge of the mucosal bed, embedding the anastomotic site and completing the reconstruction of the digestive tract. <b>Results:</b> Clinical data of 23 patients (18 from the First Affiliated Hospital of Wenzhou Medical University and 5 from the Quzhou Hospital affiliated with Wenzhou Medical University) who underwent laparoscopic proximal gastrectomy, tubular gastroesophageal anastomosis, and pure manual right flap reconstruction surgery for esophagogastric junction adenocarcinoma and proximal gastric cancer from October 2023 to August 2024. There were 15 males and 8 females, with an age of (65.3±7.7) years, the BMI was (22.9±2.8) kg/m<sup>2</sup>. All patients in the group successfully completed the surgery, with a surgery time of (218.5±38.1) minutes, including (73.5±19.2) minutes for anastomosis, intraoperative blood loss of (64.5±15.4) ml, postoperative passage of gas on (3.4±0.5) days, first consumption of liquid food after surgery of (3.9±1.1) days, and postoperative hospital stay of (9.1±0.8) days. One patient developed anastomotic stenosis (grade I) after surgery, presenting with mild swallowing obstruction, which returned to normal after dietary adjustment, and there were no cases of secondary surgery. The median follow-up time for the entire group was 4.0 (0.7-7.0) months, during which there were ","PeriodicalId":23959,"journal":{"name":"中华胃肠外科杂志","volume":"28 8","pages":"922-926"},"PeriodicalIF":0.0,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Gastroscopy and colonoscopy learning curve analysis for surgeons]. [外科医生的胃镜和结肠镜学习曲线分析]。
中华胃肠外科杂志 Pub Date : 2025-08-25 DOI: 10.3760/cma.j.cn441530-20240831-00299
C Wang, Y P Lin, Y C Cui, B Wang, W S Shen, Y S Zhou, Y Wang, Z D Gao, L M Zhang, Y J Ye
{"title":"[Gastroscopy and colonoscopy learning curve analysis for surgeons].","authors":"C Wang, Y P Lin, Y C Cui, B Wang, W S Shen, Y S Zhou, Y Wang, Z D Gao, L M Zhang, Y J Ye","doi":"10.3760/cma.j.cn441530-20240831-00299","DOIUrl":"https://doi.org/10.3760/cma.j.cn441530-20240831-00299","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the learning curves of gastroscopy and colonoscopy for surgeons. <b>Methods:</b> Clinical data of ordinary digestive endoscopy performed by gastrointestinal surgeons in Peking University People's Hospital from March, 2022 to March, 2024 were collected retrospectively. Learning curves were plotted according to the number of examinations and learning time, and the cumulative sum control chart method was used to determine the number of cases required to achieve proficiency in endoscopic examination. <b>Results:</b> Six gastrointestinal surgeons (sequentially) received training in gastroscopy and colonoscopy. All surgeons were male physicians with a doctoral degree and the professional title of attending physician. The average age was (33.0 ±1.9) years, and the average job tenure was (4.0±1.8) years. The median time required for proficiency in gastroscopy was 31 weeks, with a median number of cases of 624. Similarly, the median time required for proficiency in colonoscopy was also 31 weeks but with a median number of cases of 470. <b>Conclusions:</b> Surgeons need at least 31 weeks of independent operation to become proficient in endoscopic examination and more than 600 cases to be proficient in gastroscopy. Surgeons with gastroscopy experience also need 31 weeks of independent operation but at least 450 cases to become proficient in colonoscopy.</p>","PeriodicalId":23959,"journal":{"name":"中华胃肠外科杂志","volume":"28 8","pages":"916-921"},"PeriodicalIF":0.0,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Long-term oncological safety of robotic total gastrectomy for locally advanced proximal gastric cancer: a 5-year noninferiority comparison based on the FUGES-014 study]. [机器人全胃切除术治疗局部晚期近端胃癌的长期肿瘤安全性:基于FUGES-014研究的5年非劣效性比较]。
中华胃肠外科杂志 Pub Date : 2025-08-25 DOI: 10.3760/cma.j.cn441530-20250610-00218
Q Zhong, Z Q Zhang, Y Q Yan, Y F Li, Q C He, C H Zheng, Q Y Chen, C M Huang
{"title":"[Long-term oncological safety of robotic total gastrectomy for locally advanced proximal gastric cancer: a 5-year noninferiority comparison based on the FUGES-014 study].","authors":"Q Zhong, Z Q Zhang, Y Q Yan, Y F Li, Q C He, C H Zheng, Q Y Chen, C M Huang","doi":"10.3760/cma.j.cn441530-20250610-00218","DOIUrl":"https://doi.org/10.3760/cma.j.cn441530-20250610-00218","url":null,"abstract":"<p><p><b>Objective:</b> To report the 5-year survival outcomes and recurrence patterns of robotic total gastrectomy (RTG) for locally advanced proximal gastric cancer in order to provide more valuable long-term follow-up results for clinical practice. <b>Methods:</b> This was a prospective, single-arm, open-label clinical trial (FUGES-014; Clinical-Trials.gov, NCT03524287). Patients with locally advanced proximal gastric cancer who underwent RTG at Fujian Medical University Union Hospital from March 5, 2018, to February 10, 2020, were included in the analysis. To evaluate the long-term efficacy of RTG in the most objective manner possible, we performed a propensity score-matched (1∶2) comparative analysis with historical control patients who had undergone laparoscopic total gastrectomy (LTG) from the FUGES-002 study (ClinicalTrials.gov, NCT02333721) in which the 5-year disease-free survival (DFS), 5-year overall survival (OS), and recurrence patterns were compared between the two groups. <b>Results:</b> Prior to matching, there were 48 cases in the RTG group and 263 cases in the LTG group; patients in the LTG group had more advanced cT and pT stages (<i>P</i>=0.044 and 0.006, respectively) compared to the RTG group. After matching, there were 48 cases in the RTG group and 96 cases in the LTG group; however, no statistically significant differences were observed in the baseline clinical characteristics between the two groups (all <i>P</i>>0.05). Both groups had a median follow-up of 72 months. The 5-year DFS rates were 75.0% (95%CI: 63.7%- 88.3%) in the RTG group and 61.4% (95%CI: 52.5%-72.0%) in the LTG group (<i>P</i>=0.116). Similarly, the 5-year OS rates were 79.2% (95%CI: 68.5%-91.5%) and 64.6% (95%CI: 55.7%-74.9%) in the RTG and LTG groups, respectively (<i>P</i>=0.100). Within 5 years after surgery, tumor recurrence occurred in 10 patients (20.8%) in the RTG group and 33 patients (34.4%) in the LTG group (<i>P</i>=0.124), and peritoneal recurrence was the predominant pattern in both groups (8.3%[4/48] vs. 10.4%[10/96]; risk difference: -0.02,<i>P</i>=0.554). Gastric cancer-related death was the predominant cause of death in both groups (16.7% [8/48] vs. 31.2% [30/96]; risk difference: -0.15, <i>P</i>=0.064). Among patients stratified by different pathological stages, no statistically significant differences were found in DFS, OS, or recurrence rates between the RTG and LTG groups (all <i>P</i>>0.05). <b>Conclusions:</b> We find the long-term oncological outcomes of RTG for locally advanced proximal gastric cancer to be noninferior to those of LTG. RTG should therefore be considered as a valid option for standardized minimally invasive surgery for locally advanced proximal gastric cancer.</p>","PeriodicalId":23959,"journal":{"name":"中华胃肠外科杂志","volume":"28 8","pages":"886-894"},"PeriodicalIF":0.0,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Expert consensus on robotic surgery for colorectal cancer (2025 edition)]. 【结直肠癌机器人手术专家共识(2025年版)】。
中华胃肠外科杂志 Pub Date : 2025-08-25 DOI: 10.3760/cma.j.cn441530-20250728-00285
{"title":"[Expert consensus on robotic surgery for colorectal cancer (2025 edition)].","authors":"","doi":"10.3760/cma.j.cn441530-20250728-00285","DOIUrl":"https://doi.org/10.3760/cma.j.cn441530-20250728-00285","url":null,"abstract":"<p><p>Nowadays, robotic surgery is an important trend in the surgical treatment for colorectal cancer. Based on the previous version, the Robotic Surgery Group, Colorectal Cancer Committee of Chinese Medical Doctor Association convened the national experts to discuss and reach a consensus on the application standards for robotic colorectal cancer surgery, hoping to promote the application and promotion of robotic surgery.</p>","PeriodicalId":23959,"journal":{"name":"中华胃肠外科杂志","volume":"28 8","pages":"845-864"},"PeriodicalIF":0.0,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Comparative analysis of the efficacy of Da Vinci robot-assisted subtotal colectomy and laparoscopic surgery for slow transit constipation]. 【达芬奇机器人辅助结肠次全切除术与腹腔镜手术治疗慢传输型便秘的疗效比较分析】。
中华胃肠外科杂志 Pub Date : 2025-08-25 DOI: 10.3760/cma.j.cn441530-20241028-00355
J W Liu, S Tang, Y Wang, A L Zhu
{"title":"[Comparative analysis of the efficacy of Da Vinci robot-assisted subtotal colectomy and laparoscopic surgery for slow transit constipation].","authors":"J W Liu, S Tang, Y Wang, A L Zhu","doi":"10.3760/cma.j.cn441530-20241028-00355","DOIUrl":"https://doi.org/10.3760/cma.j.cn441530-20241028-00355","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; This study aimed to compare the clinical efficacy of da Vinci robot-assisted subtotal colectomy with laparoscopic surgery in the treatment of slow transit constipation. &lt;b&gt;Methods:&lt;/b&gt; A retrospective cohort study was performed. The clinical and follow-up data of 95 patients with slow transit constipation who underwent robotic or laparoscopic subtotal colectomy at the First Affiliated Hospital of Harbin Medical University from July, 2022 to August, 2024 and had a follow-up period of 6 months were retrospectively analyzed. Patients were divided into a robotic surgery group (43 cases) and a laparoscopic surgery group (52 cases) according to surgical approaches. All patients underwent preoperative colonic transit study, barium enema radiography, defecography, and colonoscopy to confirm the diagnosis of slow transit constipation. There were no statistically significant differences in baseline data between the two groups (all &lt;i&gt;P&lt;/i&gt;&gt;0.05). Primary observation indicators included Wexner constipation score, gastrointestinal quality of life score, and the time of first ambulation after surgery. Secondary observation indicators included operation time, intraoperative blood loss, first defecation time, length of hospital stay, postoperative defecation frequency, postoperative complications, surgical satisfaction, and postoperative pain. The Wexner constipation score was evaluated at 6 months after surgery as well, and a total score of 15 or above was defined as constipation; the higher the score, the more severe the constipation. The gastrointestinal quality of life index was also evaluated at 6 months after surgery; the lower the score, the poorer the quality of life. Pain assessment was conducted on the 2nd day after surgery using the visual analogue scale (VAS) for self-assessment, and here a higher score indicated greater pain intensity. Observe the patients' intraoperative and pastoperative conditions. &lt;b&gt;Results:&lt;/b&gt; Both groups completed the surgery unevenifullg without conversion to laparotomy, and no severe intraoperative complications occurred. Compared to the laparoscopic surgery group, the robotic surgery group had significantly shorter first ambulation time ([18.5±1.3] hours vs. [24.5±0.6] hours, &lt;i&gt;t&lt;/i&gt;=-30.437, &lt;i&gt;P&lt;/i&gt;&lt;0.001), first defecation time ([21.2±2.2] hours vs. [24.9±0.9] hours, &lt;i&gt;t&lt;/i&gt;=-10.818, &lt;i&gt;P&lt;/i&gt;&lt;0.001), and hospital stay ([7.8±1.5] days vs. [9.4±3.3] days, &lt;i&gt;t&lt;/i&gt;=-3.069, &lt;i&gt;P&lt;/i&gt;=0.003), all &lt;i&gt;P&lt;/i&gt;&lt;0.05. There were no statistically significant differences between the two groups in terms of operation time, intraoperative blood loss, postoperative pain score, defecation frequency, or incidence of postoperative complications (all &lt;i&gt;P&lt;/i&gt;&gt;0.05). Follow-up at 6 months post-operation also showed no statistically significant differences between the two groups in terms of Wexner score, gastrointestinal quality of life score, daily defecation frequency, or surgical satisfaction (all &lt;i&gt;P&lt;/i&gt;&gt;0.05). ","PeriodicalId":23959,"journal":{"name":"中华胃肠外科杂志","volume":"28 8","pages":"902-907"},"PeriodicalIF":0.0,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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