World Journal of Neuroscience最新文献_第7页

Spontaneous Intracerebral Hemorrhage: Epidemiology, Clinical Profile and Short-Term Outcome in a Tertiary Hospital in Sub-Saharan Africa 自发性脑出血:撒哈拉以南非洲一家三级医院的流行病学、临床概况和短期结果

World Journal of Neuroscience Pub Date : 2020-08-05 DOI: 10.4236/wjns.2020.103016

J. Doumbe, Khadidja Abdouramani, Daniel Massi Gams, C. M. Ayeah, C. Kenmegne, Y. Mapoure

{"title":"Spontaneous Intracerebral Hemorrhage: Epidemiology, Clinical Profile and Short-Term Outcome in a Tertiary Hospital in Sub-Saharan Africa","authors":"J. Doumbe, Khadidja Abdouramani, Daniel Massi Gams, C. M. Ayeah, C. Kenmegne, Y. Mapoure","doi":"10.4236/wjns.2020.103016","DOIUrl":"https://doi.org/10.4236/wjns.2020.103016","url":null,"abstract":"Background: Data on spontaneous \u0000intracerebral haemorrhagic (SICH) are scarce in Africa. Our objectives were to determine the prevalence of SICH, describe the clinical profile, \u0000aetiology and evaluate the prognosis (fatality case, functional outcome) of \u0000patients in a tertiary health care hospital in Cameroon. Methods: This \u0000was a hospital-based retrospective cohort which included patients with SICH and followed up for 6 months after \u0000stroke. Subarachnoid haemorrhage, cerebral venous thrombosis with bleeding or \u0000bleeding related with ischemic or brain tumour were excluded. Predictive \u0000factors were obtained using multiple logistic regression and survival by Kaplan \u0000Meier method. Results: The prevalence of SICH was 37% with male \u0000predominance (64.0%), a mean age of 55.6 ± 11.8 years. Deep coma was found in \u000030.3% on admission. The basal ganglion was the most frequent location of \u0000haemorrhage (85.1%) while intraventricular blood effusion, mass effect, \u0000cerebral oedema and herniation occurred in 31.4%, 25.7%, 8.8% and 5.0% \u0000respectively. Hypertension (57.5%) was the most common aetiology. The mean \u0000length of hospitalization was 9.0 ± 7.7 days and chest infection (30.7%) was \u0000the most frequent complication. The cumulative case fatality rate after 24 hours \u0000(day 1), during admission, month 1 and month 3 was 9.6%, 39.9%, 46.0%, 59.8% \u0000respectively. On multivariate analysis, GCS -month survival was 37.8%. Conclusion: About one-third of stroke patient were \u0000haemorrhagic. Hypertension is the leading CVRF and aetiology of spontaneous \u0000ICH. About 1 over 2 patients with SICH would die within 3 months while 50% of \u0000survivors would have a poor functional outcome at 6th month.","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"482 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77331951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Posttraumatic Stress Disorder Mediated by Exposure Level in French Civil Firefighters Following a Terrorist Attack: Some Hypotheses towards a Structural Model 恐怖袭击后法国消防人员暴露水平介导的创伤后应激障碍:结构模型的一些假设

World Journal of Neuroscience Pub Date : 2020-08-05 DOI: 10.4236/wjns.2020.103014

Angelika Wolman, Jean-Marie Stève, M. Samor, E. Bouteyre, T. Apostolidis, A. Ahmadi

{"title":"Posttraumatic Stress Disorder Mediated by Exposure Level in French Civil Firefighters Following a Terrorist Attack: Some Hypotheses towards a Structural Model","authors":"Angelika Wolman, Jean-Marie Stève, M. Samor, E. Bouteyre, T. Apostolidis, A. Ahmadi","doi":"10.4236/wjns.2020.103014","DOIUrl":"https://doi.org/10.4236/wjns.2020.103014","url":null,"abstract":"To date, few studies have investigated the impact of organizational factors such as organizational status or the rank of firefighters on the development of posttraumatic stress disorder (PTSD) following a terrorist attack. To fill this gap in the scientific literature, this field study aimed to investigate the consequences of terrorist attacks on firefighters’ psychological health in terms of PTSD. Data were collected in France following two terrorist attacks. PTSD was assessed with the PCL-S (DSM-IV) 3 to 6 months after the events. Confirmatory factor analyses (CFAs) with existing PTSD models were inconclusive, leading us to find a two-factor model via an exploratory factor analysis (EFA). A cluster analysis showed different symptom profiles that were influenced by the exposure level. Elements for a structural model explaining PTSD symptoms are proposed and suggest a central role of the exposure level. Firefighters I/II represented an at-risk sub-population, suggesting that PTSD was mainly experienced among those who performed tasks not common to their occupation.","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84482388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comorbidity between Neurotic Depression and Post-Traumatic Stress Disorder (PTSD) 神经性抑郁症与创伤后应激障碍(PTSD)的共病分析

World Journal of Neuroscience Pub Date : 2020-08-05 DOI: 10.4236/wjns.2020.103015

H. Tao, Chunru Wang, Jun-Cheng Guo, M. Guo

{"title":"Comorbidity between Neurotic Depression and Post-Traumatic Stress Disorder (PTSD)","authors":"H. Tao, Chunru Wang, Jun-Cheng Guo, M. Guo","doi":"10.4236/wjns.2020.103015","DOIUrl":"https://doi.org/10.4236/wjns.2020.103015","url":null,"abstract":"Comorbidity with PTSD has been studied at home and abroad in follow-up studies following major traumatic events, indexing patients diagnosed with PTSD and investigating rates of comorbidity and other psychiatric disorders. In practical clinical practice, the majority of patients with PTSD are diagnosed with neurosis and depression, but the clinical manifestations and treatment of some of these patients are more complicated and difficult, and it is clinically found that these patients may have comorbidities and other mental disorders. This study in hospitalized patients with neurosis and depression as the main research object, through the investigation found that some patients (36.4%) of comorbid PTSD, just, this part of the patients reported by a traumatic event is not CCMD-3 defined in the “unusual” traumatic event. Therefore, the results of this study suggest that attention should be paid to the collection of patients’ medical history, especially the inquiry of traumatic experiences. This study is only a preliminary study with a small sample size, and the conclusions obtained need to be further confirmed in future studies.","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"199 1","pages":"135-140"},"PeriodicalIF":0.0,"publicationDate":"2020-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76528228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Research Progress on the Relationship between BDNF, the Polymorphysis of Its Gene, and Childhood Autism BDNF及其基因多态性与儿童自闭症关系的研究进展

World Journal of Neuroscience Pub Date : 2020-04-09 DOI: 10.4236/wjns.2020.102012

Zhuo Liu, M. Guo, Yun-Suo Gao, Xiang-Ling Jiang

引用次数: 1

Unilateral Frontal Sinus Aspergillosis: A Case Report and Review Literature 单侧额窦曲霉病1例报告及文献复习

World Journal of Neuroscience Pub Date : 2020-04-09 DOI: 10.4236/wjns.2020.102011

Yannick CANTON. Kessely, Félicien G. Toudjingar, Loobé Regis Mwabanyol, Mahamat Ali Bolti, Aboubakar Aouami, K. Ndiaye, Olivier Ouambi, Y. Ali, M. Ba

引用次数: 0

Case Study on Focal Retrograde Amnesia due to Limbic Encephalitis 边缘脑炎致局灶性逆行性遗忘1例

World Journal of Neuroscience Pub Date : 2020-04-09 DOI: 10.4236/wjns.2020.102010

Nobuhiro Takahashi, M. Kawamura, Naoki Tanihara, Mamiko Sato, Yasutaka Kobayashi

{"title":"Case Study on Focal Retrograde Amnesia due to Limbic Encephalitis","authors":"Nobuhiro Takahashi, M. Kawamura, Naoki Tanihara, Mamiko Sato, Yasutaka Kobayashi","doi":"10.4236/wjns.2020.102010","DOIUrl":"https://doi.org/10.4236/wjns.2020.102010","url":null,"abstract":"This case study addresses episodic memory impairment or focal retrograde amnesia related to limbic encephalitis. The patient in question was a right-handed man in his 60s who developed focal retrograde amnesia due to limbic encephalitis. An abnormal MRI signal was observed in the right medial temporal lobe. Immediately after the encephalitis onset, mental symptoms—including impaired consciousness, disorientation, hallucinations, and delusions—appeared; however, his condition improved with medical treatment. After transfer to a convalescent and rehabilitation hospital, various neuropsychological tests were conducted but no apparent functional decline was observed in intellectual function, attention, memorization, or retention. However, the patient exhibited impairments related to autobiographical memory and memory of events 4 - 5 years before the onset of limbic encephalitis. Based on these observations, the patient was considered to exhibit focal retrograde amnesia due to limbic encephalitis. Despite exhibiting retrograde amnesia, he had no difficulty in his daily life in the ward. Moreover, after discharge from hospital, smooth work reinstatement was possible. This case demonstrates that, even after exhibiting retrograde amnesia, if its duration is relatively short and physical function and other higher-order brain functions are sustained, social rehabilitation—including work reinstatement—is feasible.","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"82 1","pages":"91-100"},"PeriodicalIF":0.0,"publicationDate":"2020-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76626025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immunotherapy for the Post-Infectious Sequela of SARS-CoV-2 Infection SARS-CoV-2感染后后遗症的免疫治疗

World Journal of Neuroscience Pub Date : 2020-04-09 DOI: 10.4236/wjns.2020.102013

D. Younger

引用次数: 2

Concurrent Validity of a Virtual Version of Box and Block Test for Patients with Neurological Disorders 虚拟盒块测验对神经系统疾病患者的并发效度

World Journal of Neuroscience Pub Date : 2020-02-21 DOI: 10.4236/wjns.2020.101009

M. Alvarez-Rodríguez, E. López-Dolado, M. Salas-Monedero, V. Lozano-Berrio, S. Ceruelo-Abajo, Á. Gil-Agudo, A. Reyes-Guzmán

{"title":"Concurrent Validity of a Virtual Version of Box and Block Test for Patients with Neurological Disorders","authors":"M. Alvarez-Rodríguez, E. López-Dolado, M. Salas-Monedero, V. Lozano-Berrio, S. Ceruelo-Abajo, Á. Gil-Agudo, A. Reyes-Guzmán","doi":"10.4236/wjns.2020.101009","DOIUrl":"https://doi.org/10.4236/wjns.2020.101009","url":null,"abstract":"Background: The Box and Block clinical test is a validated and standardized scale for use in the clinical environment that allows the assessment of rough manipulative dexterity. Proposing virtual methods to carry out these assessments is an attempt to eliminate some of the subjectivity that the test may entail depending on the observer and the way in which the patient gives instructions. Applied to the assessment of skills after neurological pathologies, previous experiences in stroke patients have been found. So, this work was centered on the Spinal Cord Injury. Objective: To present the virtual application of the Box and Block scale, as well as details about its design and development for its manipulation based on Leap Motion Controller. Methodology: The relationship between the results obtained in the actual test and in the virtual application in healthy subjects and, mostly, patients with cervical spinal cord injury is analyzed, obtaining a high correlation index between both tests’ performance. Results: A high correlation index was obtained between both tests performance, the real and virtual version of the Box and Block Test. Conclusion: This virtual test can serve as an element to evaluate in the future the effectiveness of the RehabHand prototype based on virtual reality applications with a therapeutic and a rehabilitative sense that, manipulated from Leap Motion Controller, allow the improvement of the manipulative dexterity in patients with neurological diseases such as spinal cord injury.","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87466761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

The Effects of Task Order Administration on Test Scores from the Trail Making Test: Near-Infrared Spectroscopy Investigations 任务指令管理对造径测试成绩的影响:近红外光谱研究

World Journal of Neuroscience Pub Date : 2020-02-12 DOI: 10.4236/wjns.2020.101008

C. Takeda, M. Notoya, Nobuyuki Sunahara

{"title":"The Effects of Task Order Administration on Test Scores from the Trail Making Test: Near-Infrared Spectroscopy Investigations","authors":"C. Takeda, M. Notoya, Nobuyuki Sunahara","doi":"10.4236/wjns.2020.101008","DOIUrl":"https://doi.org/10.4236/wjns.2020.101008","url":null,"abstract":"This research examines the effects of task administration on Trail Making Test performance. The TMT consists of two parts, TMT Part A and TMT Part B. Generally, it has been believed that the order the two parts are completed does not influence test results; however, there is one previous study that has suggested that the order is indeed an influential factor on test scores. To measure frontal lobe function, the present study used near-infrared spectroscopy to measure changes in oxygenated hemoglobin (oxy-Hb) in 48 young, healthy Japanese subjects as they completed Parts A and B. We subtracted the change in oxy-Hb while completing Part A from that while completing Part B (B-A Oxy-Hb) for a comparison to facilitate an investigation of how, or if, the order in which the TMT is taken influences test success. We found that when Part A was completed first, there were only small changes in the B-A oxy-Hb, but when Part B was completed first, there were larger changes. This study indicates that the order the tests are completed in may influence outcomes, thus assessments using the TMT must follow a consistent task order.","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83089109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What Strategy for a Severe Stroke in Africa: Palliative Care or Unreasonable Obstinacy? 对非洲严重中风采取什么策略:姑息治疗还是不合理的固执?

World Journal of Neuroscience Pub Date : 2020-02-10 DOI: 10.4236/wjns.2020.101006

P. Ossou-Nguiet, G. Mpandzou, Dina Happhia Motoula Latou, J. Diatewa, Karen Obondzo Aloba, P. E. S. Bandzouzi, B. E. Mbolla

{"title":"What Strategy for a Severe Stroke in Africa: Palliative Care or Unreasonable Obstinacy?","authors":"P. Ossou-Nguiet, G. Mpandzou, Dina Happhia Motoula Latou, J. Diatewa, Karen Obondzo Aloba, P. E. S. Bandzouzi, B. E. Mbolla","doi":"10.4236/wjns.2020.101006","DOIUrl":"https://doi.org/10.4236/wjns.2020.101006","url":null,"abstract":"Introduction: Palliative care, firstly used for chronic diseases, is currently indicated for some acute pathology such as Stroke. Its implementation improves the quality of care for end-of-life patients. The aim of our study is to report a series of patients who died in the intensive care stroke unit of Brazzaville. Method: It was a descriptive study of a series of 13 cases of severe stroke, admitted to the intensive care unit of the university hospital of Brazzaville, between January 2015 and December 2017. Sociodemographic, clinical, paraclinical and prognostic variables were studied. Result: The mean age of the patients was 46 ± 11.5 years with a male predominance in 69.2% (n = 9). They were all hypertensive. The motor deficit and consciousness disorder association was the reason for admission in 84.6% (n = 11) and an epileptic seizure of 15.4% (n = 2). The mean NIHSS at admission was 21 ± 5, that of Glasgow 6 ± 3. Stroke was hemorrhagic in 84.6% (n = 11) and malignant infarction in 15.4% (n = 2). All of these patients received invasive resuscitation with assisted ventilation and all died within 8 days of admission. Conclusion: The issue of limitation of care deserves to be debated, and is proposed on a case-by-case basis, in the face of a serious stroke. Therapeutic relentlessness is not only expensive, but also raises the problem of suffering of the individual at the end of life.","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87056245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0