journal of test deposits最新文献

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Canary: 9d043766-0ac6-4f43-b76f-54b3ca203d6b
journal of test deposits Pub Date : 2020-01-05 DOI: 10.5555/CANARY-10
Zuleika Dogson
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引用次数: 0
Canary: 2d8e455f-cd3f-4326-9dd1-95b8784be643
journal of test deposits Pub Date : 2020-01-05 DOI: 10.5555/CANARY-22
Zuleika Dogson
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引用次数: 0
Canary: c84fd7ba-4ceb-4176-a1c2-bfe03a1ce216
journal of test deposits Pub Date : 2020-01-05 DOI: 10.5555/CANARY-19
Zuleika Dogson
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引用次数: 0
Background selection and biased gene conversion affect more than 95% of the human genome and bias demographic inferences 背景选择和有偏见的基因转换影响超过95%的人类基因组和偏见人口统计推断
journal of test deposits Pub Date : 2019-03-03 DOI: 10.5555/5638632
Fanny Pouyet
{"title":"Background selection and biased gene conversion affect more than 95% of the human genome and bias demographic inferences","authors":"Fanny Pouyet","doi":"10.5555/5638632","DOIUrl":"https://doi.org/10.5555/5638632","url":null,"abstract":"Disentangling the effect on genomic diversity of natural selection from that of demography is notoriously difficult, but necessary to properly reconstruct the history of species. Here, we use high-quality human genomic data to show that purifying selection at linked sites (i.e. background selection, BGS) and GC-biased gene conversion (gBGC) together affect as much as 95% of the variants of our genome. We find that the magnitude and relative importance of BGS and gBGC are largely determined by variation in recombination rate and base composition. Importantly, synonymous sites and non-transcribed regions are also affected, albeit to different degrees. Their use for demographic inference can lead to strong biases. However, by conditioning on genomic regions with recombination rates above 1.5 cM/Mb and mutation types (C↔G, A↔T), we identify a set of SNPs that is mostly unaffected by BGS or gBGC, and that avoids these biases in the reconstruction of human history. more","PeriodicalId":237229,"journal":{"name":"journal of test deposits","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128266191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Test article for crossref test journal 用于交叉测试日志的测试文章
journal of test deposits Pub Date : 2018-01-30 DOI: 10.5555/test_jms_123_article_1
J. Stark
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引用次数: 0
test october article id 测试十月文章编号
journal of test deposits Pub Date : 2013-10-31 DOI: 10.5555/TEST10312013-2
Vai Pat
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引用次数: 0
test october 31 10月31日考试
journal of test deposits Pub Date : 2013-10-31 DOI: 10.5555/TEST10312013
va pa
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引用次数: 0
test sept 19 9月19日考试
journal of test deposits Pub Date : 2013-09-19 DOI: 10.5555/TEST09192013
V. patel
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引用次数: 0
Test force alias one 试验力别名一
journal of test deposits Pub Date : 2013-06-20 DOI: 10.5555/TEST_FORCE-ALIAS-06-10-1
Vitsiak Pi
{"title":"Test force alias one","authors":"Vitsiak Pi","doi":"10.5555/TEST_FORCE-ALIAS-06-10-1","DOIUrl":"https://doi.org/10.5555/TEST_FORCE-ALIAS-06-10-1","url":null,"abstract":"","PeriodicalId":237229,"journal":{"name":"journal of test deposits","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134178726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Test force alias june 测试力别名6月
journal of test deposits Pub Date : 2013-06-20 DOI: 10.50505/2013TEST_CONFLICT_JULY_RETEST101
Vai Pat
{"title":"Test force alias june","authors":"Vai Pat","doi":"10.50505/2013TEST_CONFLICT_JULY_RETEST101","DOIUrl":"https://doi.org/10.50505/2013TEST_CONFLICT_JULY_RETEST101","url":null,"abstract":"","PeriodicalId":237229,"journal":{"name":"journal of test deposits","volume":"179 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134284153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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