Clin Nuclear Med最新文献_第3页

Hepatobiliary Scintigraphic Findings in Obstructed Intrahepatic Choledochal Cyst Before and After Surgery 梗阻性肝内胆总管囊肿术前、术后肝胆造影表现

Clin Nuclear Med Pub Date : 2001-04-01 DOI: 10.1097/00003072-200104000-00010

Rakesh Kumar, S. Choudhury, B. Dasan J, S. Agarwala, A. Malhotra

引用次数: 2

Neonatal Hypothyroid Disease: Absent Salivary Gland Evident on Technetium-99m Pertechnetate Scan 新生儿甲状腺功能减退:99m高锝扫描显示唾液腺缺失

Clin Nuclear Med Pub Date : 2001-04-01 DOI: 10.1097/00003072-200104000-00006

P. Ozgen Kiratli, I. Gordon

{"title":"Neonatal Hypothyroid Disease: Absent Salivary Gland Evident on Technetium-99m Pertechnetate Scan","authors":"P. Ozgen Kiratli, I. Gordon","doi":"10.1097/00003072-200104000-00006","DOIUrl":"https://doi.org/10.1097/00003072-200104000-00006","url":null,"abstract":"Purpose Technetium-99m pertechnetate scintigraphy is a well-established technique for diagnosing congenital hypothyroid disease. However, the biodistribution of pertechnetate (Tc04-) in neonates and young infants is not well documented. The purpose of this study was to analyze and document the biodistribution of TcO4- in young infants. Materials and Methods Scintigraphic studies of 31 patients being examined for hypothyroid disease were analyzed. All patients had elevated levels of thyroid-stimulating hormone. Dyshormonogenesis was diagnosed in 7 patients, ectopic thyroid glands in 19, and agenesis in 5. Results Images of the neck, chest, and abdomen taken in the anterior and left lateral positions using a low-energy, all-purpose collimator were reviewed. Twenty-six of the patients had no accumulation of the isotope in the salivary glands and 11 had no gastric uptake on either view. Conclusions Based on the absence of salivary gland activity in the patients examined, this study suggests that this is a normal finding in infants younger than 3 months. A lateral view of the neck with markers is sufficient to localize the thyroid gland, because any activity in the neck region would belong to the thyroid. Furthermore, poor and variable uptake of the isotope in the stomach may lead to false-negative results, so caution is urged in the use of this tracer in Meckel’s scintigraphy in young infants, particularly if the study findings are within normal limits.","PeriodicalId":236509,"journal":{"name":"Clin Nuclear Med","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128202155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Detection of Minimal Residual Disease in Acute Leukemia by Tc-99m MIBI Femoral Marrow Imaging Tc-99m - MIBI股骨髓显像检测急性白血病微小残留病变

Clin Nuclear Med Pub Date : 2001-04-01 DOI: 10.1097/00003072-200104000-00009

S. Wakasugi, K. Ohta, Y. Hasegawa, N. Tatumi

{"title":"Detection of Minimal Residual Disease in Acute Leukemia by Tc-99m MIBI Femoral Marrow Imaging","authors":"S. Wakasugi, K. Ohta, Y. Hasegawa, N. Tatumi","doi":"10.1097/00003072-200104000-00009","DOIUrl":"https://doi.org/10.1097/00003072-200104000-00009","url":null,"abstract":"To determine the potential of Tc-99m MIBI femoral marrow imaging for detecting minimal residual disease in acute leukemia, MIBI images of 68 patients with acute leukemia and 110 control patients were examined. MIBI accumulation was classified into three patterns: not detectable, mild accumulation, and clearly visualized accumulation. Clearly visualized accumulation was interpreted as abnormal. The mean uptake ratio of the femoral marrow to muscle was calculated. Forty-five patients who were in complete remission (CR) at the time of MIBI imaging had a follow-up study (mean interval, 23 months). Clearly visualized accumulation was demonstrated in 35 patients with acute leukemia: in 7 patients before starting induction chemotherapy, in 12 patients after relapse, and in 16 of the 49 patients in the CR group. Mild accumulation was demonstrated in 14 patients in the CR group and in 13 control group patients. No detectable accumulation was observed in 19 patients in the CR group and in 97 control patients. The marrow and muscle uptake ratio of patients before starting chemotherapy (2.29 ± 0.26) was greater compared with that in patients after relapse (1.78 ± 0.44, P < 0.02) and in patients with abnormal accumulation despite complete remission (1.84 ± 0.36, P < 0.01). The uptake ratio in patients with abnormal accumulation despite CR was higher compared with patients with mild accumulation in CR (1.26 ± 0.13, P < 0.001) and controls (1.23 ± 0.10, P < 0.001) who had mild accumulation. Fifteen patients with abnormal accumulation despite CR had a markedly greater relapse rate (66.7% > 10.0%, P < 0.005), a higher mortality rate (46.7% > 6.7%, P < 0.01), and shorter remission time (8.7 ± 10.2 months < 35.9 ± 20.1 months, P < 0.001) compared with 30 patients without abnormal accumulation in CR. MIBI femoral marrow imaging may be a useful and simple method for monitoring levels of residual leukemic cells. Clearly visualized MIBI accumulation may be a marker for relapse.","PeriodicalId":236509,"journal":{"name":"Clin Nuclear Med","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128862834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Ectopic Goiter Masquerading as Submandibular Gland Swelling: A Case Report and Review of the Literature 异位甲状腺肿伪装为颌下腺肿大:1例报告及文献复习

Clin Nuclear Med Pub Date : 2001-04-01 DOI: 10.1097/00003072-200104000-00005

Rakesh Kumar, S. Sharma, A. Marwah, D. Moorthy, D. Dhanwal, A. Malhotra

引用次数: 64

F-18 FDG Uptake in the Large Arteries: A New Observation F-18 FDG在大动脉中的摄取:一种新的观察

Clin Nuclear Med Pub Date : 2001-04-01 DOI: 10.1097/00003072-200104000-00007

M. Yun, D. Yeh, Louis Araujo, S. Jang, A. Newberg, A. Alavi

{"title":"F-18 FDG Uptake in the Large Arteries: A New Observation","authors":"M. Yun, D. Yeh, Louis Araujo, S. Jang, A. Newberg, A. Alavi","doi":"10.1097/00003072-200104000-00007","DOIUrl":"https://doi.org/10.1097/00003072-200104000-00007","url":null,"abstract":"Purpose The cellular components of the atherosclerotic plaque, such as macrophages, exhibits high glucose metabolic activity. The aim of this study was to show the frequency of vascular uptake and possibly to explain the significance of this finding on fluorodeoxyglucose (FDG) positron emission tomographic (PET) scans. Methods We evaluated the presence of FDG vascular uptake in 132 consecutive patients undergoing whole-body PET scans and 5 patients who had only lower extremity scans. The presence of vascular FDG uptake was assessed in the abdominal aorta, iliac, and proximal femoral arteries on the 132 whole-body scans, whereas only the femoral and the popliteal arteries were examined on the leg scans. The patients’ ages ranged from 20 to 80 years, and they were divided into three age groups: 35 patients were younger than 40 years (group 1; mean age, 32.4 years), 48 patients were 41 to 60 years (group 2; mean age, 50.3 years), and 54 patients were older than 60 years (group 3; mean age, 70.3 years). Results Fifty percent (69 of 137) of the total population showed vascular FDG uptake in at least one vessel. Thirty-four percent (12 of 35) of group 1, 50% (24 of 48) of group 2, and 61% (33 of 54) of group 3 showed vascular wall uptake (P = 0.017 between groups 1 and 3). In addition, the correlation between the mean age of the age groups and the prevalence of FDG vascular uptake is strong (r = 0.99). Conclusions Vascular FDG uptake is present in 50% of the patients examined for this study, with an increased prevalence in older patients. This vascular uptake might be explained by smooth muscle metabolism in the media, subendothelial smooth muscle proliferation from senescence, and the presence of macrophages within the atherosclerotic plaque. The relative contribution of these sources needs further investigation.","PeriodicalId":236509,"journal":{"name":"Clin Nuclear Med","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115884750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 227

Radionuclide Lung Imaging in Respiratory Decompression Sickness: Potential Role in the Diagnosis and Evaluation of Hyperbaric Therapy 呼吸减压病的放射性核素肺显像:在高压氧治疗的诊断和评价中的潜在作用

Clin Nuclear Med Pub Date : 2001-04-01 DOI: 10.1097/00003072-200104000-00008

M. Radaideh, L. Lamki, B. Barron, Shehab M. Elshazly

{"title":"Radionuclide Lung Imaging in Respiratory Decompression Sickness: Potential Role in the Diagnosis and Evaluation of Hyperbaric Therapy","authors":"M. Radaideh, L. Lamki, B. Barron, Shehab M. Elshazly","doi":"10.1097/00003072-200104000-00008","DOIUrl":"https://doi.org/10.1097/00003072-200104000-00008","url":null,"abstract":"Of the more than 3.5 million trained divers in the United States, many will experience various illnesses specific to divers. Most of these illnesses are related to the changes in absolute pressure that divers experience while diving. During and after ascent, a diver is at risk for decompression sickness and pulmonary barotrauma. A very rare casualty is pulmonary decompression sickness from immersion. This is a literature review and case report of a young woman with acute respiratory decompression sickness who had defects on perfusion lung imaging after a diving accident and after hyperbaric oxygen therapy. However, the perfusion defects reverted to normal in less than 24 hours. Possible explanations for the changes in the appearances of the scans are offered and discussed. This case report shows the potential utility of lung scanning in the diagnostic examination of these patients and the evaluation of the adequacy of treatment with hyperbaric oxygen therapy. A greater use of ventilation–perfusion lung scans in the treatment of such patients may establish its role more definitely.","PeriodicalId":236509,"journal":{"name":"Clin Nuclear Med","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127564018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Iodine-131 Ablation Therapy for a Patient Receiving Peritoneal Dialysis 碘-131消融治疗一例腹膜透析患者

Clin Nuclear Med Pub Date : 2001-04-01 DOI: 10.1097/00003072-200104000-00004

M. Toubert, C. Michel, F. Métivier, M. CAN PEKER, J. Rain

{"title":"Iodine-131 Ablation Therapy for a Patient Receiving Peritoneal Dialysis","authors":"M. Toubert, C. Michel, F. Métivier, M. CAN PEKER, J. Rain","doi":"10.1097/00003072-200104000-00004","DOIUrl":"https://doi.org/10.1097/00003072-200104000-00004","url":null,"abstract":"The authors describe a patient with follicular thyroid carcinoma who was receiving continuous ambulatory peritoneal dialysis to manage end-stage renal disease. To deliver radioiodine therapy to ablate thyroid remnants safely and under optimal conditions, the behavior of 37 MBq (1 mCi) I-131 was followed daily for 3 days. Blood activity and total body count decreased with a half-life of 100 hours (4.17 days). The daily iodide removal rate, estimated as a percentage of the total administrated activity, was low: 5.3% to 8.6% in peritoneal dialysate and 1.3% to 2.2% in urine. The thyroid uptake, measured using a probe, was 2.4% to 2.1% from day 1 to day 3 and 1.9% later at day 8. The volume of thyroid remnants was determined by ultrasonography to be 0.6 g. The patient received a reduced ablative I-131 dose of 814 MBq (22 mCi). Radiation emitted from the patient after I-131 therapy, monitored using a radiation monitor probe located at a distance of 1 meter, decreased with an effective half-life of 70 hours (2.9 days). The integration of the curve from t = 0 showed a level always less than 25 &mgr;Sv/hour as early as 24 hours after treatment. Because the iodine removal rate is continuous but low in a case of peritoneal dialysis, smaller therapeutic doses must be administered to deliver maximal radiation to residual thyroid tissue while minimizing excessive radiation exposure to patients, their families, and medical staff.","PeriodicalId":236509,"journal":{"name":"Clin Nuclear Med","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128895097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 29

Clinical Advantages of Interictal SPECT Coregistered to Magnetic Resonance Imaging in Patients with Epilepsy 癫痫患者间期SPECT与磁共振成像联合应用的临床优势

Clin Nuclear Med Pub Date : 2001-04-01 DOI: 10.1097/00003072-200104000-00011

T. Shiga, K. Morita, A. Takano, C. Katoh, E. Tsukamoto, T. Koyama, H. Iida, N. Tamaki

{"title":"Clinical Advantages of Interictal SPECT Coregistered to Magnetic Resonance Imaging in Patients with Epilepsy","authors":"T. Shiga, K. Morita, A. Takano, C. Katoh, E. Tsukamoto, T. Koyama, H. Iida, N. Tamaki","doi":"10.1097/00003072-200104000-00011","DOIUrl":"https://doi.org/10.1097/00003072-200104000-00011","url":null,"abstract":"Purpose The aim of this study was to investigate the clinical value of coregistration of interictal SPECT and magnetic resonance imaging (MRI) in patients with partial epilepsy. Materials and Methods Seventeen patients with partial epilepsy were examined with I-123 IMP or Tc-99m ethyl cysteinate dimer SPECT during the interictal phase. The SPECT images were automatically coregistered to axial T1 weighted MRIs. Asymmetry indexes (AIs) were calculated in both nonregistered images and coregistered images. Results SPECT images showed areas of decreased tracer uptake in 12 patients. In two patients, the relation between the tumor and the extent of decreased uptake became more accurate in the coregistered images. In five cases, the coregistered images clearly showed that the decreased uptake was located in the sulcus. The AIs were significantly reduced from 14.29 ± 7.23 to 5.86 ± 3.48 (P < 0.001) after the images were coregistered in these cases. In five cases, the coregistered images indicated that the decreased areas were in agreement with the cortical findings. No significant differences in the AIs were observed in these cases (16.50 ± 6.19 versus 17.83 ± 4.45). Thus, the coregistered images were useful not only to differentiate actual hypoperfusion from artificial hypoperfusion resulting from partial volume effects but also to improve the accuracy of AIs. Conclusion The coregistration of interictal perfusion SPECT and MRI is useful not only to provide precise functional and anatomic mapping but also to improve the accuracy of calculations of the semiquantitative analysis of regional cerebral blood flow parameters during the interictal state of epilepsy.","PeriodicalId":236509,"journal":{"name":"Clin Nuclear Med","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128144828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

F-18 FDG Positron Emission Tomography in Primary Breast Non-Hodgkin’s Lymphoma F-18 FDG正电子发射断层扫描在原发性乳腺非霍奇金淋巴瘤中的应用

Clin Nuclear Med Pub Date : 2001-04-01 DOI: 10.1097/00003072-200104000-00003

S. Bakheet, R. Bakheet, A. Ezzat, A. Tulbah, A. Duraković, S. Hussain

{"title":"F-18 FDG Positron Emission Tomography in Primary Breast Non-Hodgkin’s Lymphoma","authors":"S. Bakheet, R. Bakheet, A. Ezzat, A. Tulbah, A. Duraković, S. Hussain","doi":"10.1097/00003072-200104000-00003","DOIUrl":"https://doi.org/10.1097/00003072-200104000-00003","url":null,"abstract":"A 50-year-old woman had an irregular, mobile, firm right breast mass that became progressively larger in the past 3 months that measured 18 × 15 cm at the time of examination. She had no nipple discharge or skin changes. A 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography (FDG PET) showed a ring-shaped breast uptake consisting of high peripheral glycolytic activity and a cold center most likely representing necrosis or hemorrhage despite the absence of a history of trauma, surgical intervention, chemotherapy, or radiation to the breast. Whole-body images did not show any evidence of lymph node involvement or distant metastases. These results were confirmed by computed tomography of the chest, abdomen, and pelvis. Cytologic examination of a fine-needle aspiration of the breast mass showed diffuse large B-cell, intermediate grade, non-Hodgkin’s lymphoma. Although it occurs infrequently, primary breast lymphoma should be considered in patients with a breast mass that shows a ring-shaped FDG uptake. A PET scan, in contrast to other imagining techniques, offers the advantage of screening the entire body, excluding the presence of metastases, and confirming the primary origin of the breast lymphoma.","PeriodicalId":236509,"journal":{"name":"Clin Nuclear Med","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132969427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 23

Heroin-Induced Rhabdomyolysis as a Cause of Reflex Sympathetic Dystrophy 海洛因诱导的横纹肌溶解是反射性交感神经营养不良的原因

Clin Nuclear Med Pub Date : 2001-04-01 DOI: 10.1097/00003072-200104000-00001

Bi‐Fang Lee, N. Chiu, Wei-Hsi Chen, G. Liu, H‐S. Yu

引用次数: 4