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A Comparative Study with Carvedilol and Ivabradine in Ischaemic Heart Disease Patients with Heart Failure 卡维地洛与伊伐布雷定治疗缺血性心脏病心力衰竭的比较研究
University Heart Journal Pub Date : 2019-08-18 DOI: 10.3329/UHJ.V15I2.42648
H. Hoque, Khurshed Ahmed, M. F. Kabir, N. Fatema
{"title":"A Comparative Study with Carvedilol and Ivabradine in Ischaemic Heart Disease Patients with Heart Failure","authors":"H. Hoque, Khurshed Ahmed, M. F. Kabir, N. Fatema","doi":"10.3329/UHJ.V15I2.42648","DOIUrl":"https://doi.org/10.3329/UHJ.V15I2.42648","url":null,"abstract":"Abstract not available \u0000University Heart Journal Vol. 15, No. 2, Jul 2019; 60-62","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81355596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Personal Profile and Risk Factors between Patients with Ischaemic and Haemorrhagic Stroke 缺血性脑卒中与出血性脑卒中患者个人特征及危险因素比较
University Heart Journal Pub Date : 2019-08-18 DOI: 10.3329/UHJ.V15I2.42645
A. S. Masum, Kazi Jannat Ara, Atia Saeed, Shakil Shams, Mohiuddin, M. Hannan, Shahidullah Sabuj, N. Fatema
{"title":"Comparison of Personal Profile and Risk Factors between Patients with Ischaemic and Haemorrhagic Stroke","authors":"A. S. Masum, Kazi Jannat Ara, Atia Saeed, Shakil Shams, Mohiuddin, M. Hannan, Shahidullah Sabuj, N. Fatema","doi":"10.3329/UHJ.V15I2.42645","DOIUrl":"https://doi.org/10.3329/UHJ.V15I2.42645","url":null,"abstract":"Stroke is the third leading cause of death in adult population throughout the world and is the most common cause of severe adult physical disability. It is increasing at an alarming rate in Asia including Bangladesh. The assessment of the frequency of development of various types of complications of stroke is important for proper management after acute stroke and its primary and secondary prevention. The aims of the study were to observe the complications in patients with ischemic and hemorrhagic stroke.A cross sectional observational study was conducted from September 2015 to April 2017 in the department of Neurology, Bangabandhu Sheikh Mujib Medical University, Dhaka. All the patients of ischemic and hemorrhagic stroke confirmed by neuroimaging (CT scan of head/ MRI of brain), meeting the inclusion and exclusion criteria were included in the study.Our study was performed with eighty stroke patients. Among them sixty five were ischemic and fifteen were hemorrhagic stroke patients. Present study showed that maximum stroke patients were more than 50 years of age. Mean age of the study population was 59.28 ± 13.98 years and 60.07 ± 17.29 years in ischaemic stroke patients and haemorrhagic stroke patients respectively. Stroke incidence rate is 1.25 times greater in men than women. \u0000University Heart Journal Vol. 15, No. 2, Jul 2019; 42-46","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82093756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Thrombolysis in Myocardial Infarction (TIMI) Risk Score with Angiographic Severity of Coronary Artery Disease In Patients with Non-ST Elevation Acute Coronary Syndrome 非st段抬高急性冠状动脉综合征患者心肌梗死溶栓(TIMI)风险评分与冠状动脉疾病血管造影严重程度的关系
University Heart Journal Pub Date : 2019-08-18 DOI: 10.3329/UHJ.V15I2.42649
A. Bashiruddin, M. Chowdhury, B. Bhattacharjee, Abul Hossen Shahin, S. Ahsan, Mrm Mandal, S. Dhar, I. Mahmud, S. Hossain
{"title":"Association of Thrombolysis in Myocardial Infarction (TIMI) Risk Score with Angiographic Severity of Coronary Artery Disease In Patients with Non-ST Elevation Acute Coronary Syndrome","authors":"A. Bashiruddin, M. Chowdhury, B. Bhattacharjee, Abul Hossen Shahin, S. Ahsan, Mrm Mandal, S. Dhar, I. Mahmud, S. Hossain","doi":"10.3329/UHJ.V15I2.42649","DOIUrl":"https://doi.org/10.3329/UHJ.V15I2.42649","url":null,"abstract":"Background: Clinical guidelines recommend that optimal management of acute coronary syndrome (ACS) should include patient risk stratification. Predicting the anatomical extension of coronary artery disease (CAD) is also potentially useful for clinical decision. \u0000Objective: The objective of our study was to determine whether the TIMI risk score correlates with the angiographic extent and severity of CAD in patients with NSTE- ACS. \u0000Materials and Methods: This was a cross-sectional observational study carried out in the Department of Cardiology, Chattogram Medical College Hospital (CMCH) from September 2017 to May 2018. A total of 200 patients diagnosed with NSTE- Acute Coronary Syndrome were included as sample by purposive sampling method. TIMI risk score for each patient was calculated and the patients were stratified into 3 groups according to the TIMI risk score: low risk (0-2); intermediate risk (3-4); high risk (5-7). The severity of the CAD was assessed by Vessel score and Gensini score. \u0000Result: The mean ± SD of the age of study population was 53.7 ±10.8 years (range 37–77) and 142 (71%) were male. Regarding cardiovascular risk factors, 137 (68.5%) patients had diabetes mellitus, 83 (41.5%) had dyslipidaemia, 155 (77.5%) had hypertension, 136 (68%) were current smoker and 70 (35%) had a family history of CAD. The Gensini score was higher in patients at high risk TIMI group (p<0.001). Moreover, there was a signiûcant positive correlation between the TIMI and Gensini score (r=0.446,p<0.001). TIMI score can predict significant CAD moderately well (area under the curve 0.661, p=0.001). Patients with TIMI score > 4 were more likely to have significant three vessel CAD (65.9%) versus those with TIMI risk score 3-4 (17.9%) and TIMI risk score < 3 (2%) (p< 0.001). \u0000Conclusion: Study showed the TIMI score is significantly correlated with the extent of CAD as assessed by the Gensini score. It is accurate for predicting severe CAD among NSTE-ACS patients. \u0000University Heart Journal Vol. 15, No. 2, Jul 2019; 68-73","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84467351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcome of Albumin Infusion in Heart Failure Patients 心力衰竭患者输注白蛋白的疗效
University Heart Journal Pub Date : 2019-08-18 DOI: 10.3329/UHJ.V15I2.42646
A. Talukder, M. Siraj, N. Khondokar, S. Habib, A. Salim, Mohammad Walidur Rahman, S. Banerjee, S. Ahsan, H. Hoque, F. Rahman
{"title":"Outcome of Albumin Infusion in Heart Failure Patients","authors":"A. Talukder, M. Siraj, N. Khondokar, S. Habib, A. Salim, Mohammad Walidur Rahman, S. Banerjee, S. Ahsan, H. Hoque, F. Rahman","doi":"10.3329/UHJ.V15I2.42646","DOIUrl":"https://doi.org/10.3329/UHJ.V15I2.42646","url":null,"abstract":"Background: Heart Failure (HF) is a major public health burden worldwide. Approximately 5 million Americans, 0.4–2% of the general European population and over 23 million people worldwide are living with heart failure. Like few other chronic disease, low serum albumin is common in patients with heart failure (HF). However, very few studies evaluated the outcome of albumin infusion in different stages of HF. Therefore, the objective of this study is to assess the outcome of albumin infusion in heart failure patients. \u0000Methods: It was a cross-sectional study. A total of 50 cases of chronic heart failure with reduced ejection fraction and NYHA class III or IV with serum albumin level <2.5g/dl who were admitted in CCUwere selected by purposive sampling, from September 2017 to August 2018. 100ml of 20% albumin was infused and serum albumin was measured after 3 days. Then the patients were divided into two groups, Patients who failed to attain serum albumin of 3g/dl(Group A) or Patients who attained serum albumin of ≥3g/dl (Group B). Analysis and comparison for symptomatic improvement of heart failure by NHYA classification and LVEF was done at 10th day after infusion between group A and B. \u0000Result: Among the 50 patients, mean age of patients was 53.64 ± 13.44 years (age range: 26-84 years) with a male-female ratio of 3:2 (60%-male vs 40%- female). Majority patients were previously re-admitted at least two times (40%), 28% were re-admitted once, 16% were re-admitted three times and 4% were re-admitted for four times. Of all, 56% patients presented NYHA class IV and AHA stage D heart failure (56%) and 44% patients presented with NYHA class III and AHA stage C. At day 10 follow up following albumin infusion, overall frequency of following ten days of albumin therapy, in group B, 8 patients (72.7%) among Class III improved to Class I and 3 patients (27.3%) improved to class II. Also, 7 patients (50%), 5 patients (35.7%) and 2 patients (14.3%) among class IV improved to respectively class I, class II and class III. In group A, 3 patients (27.3%) among class III improve to class II and 8 patients (72.7%) remain in class III. Also, 2 patients (14.3%), 5 Patients (35.7%) and 7 patients (50%) among class IV improve to respectively class I, class II and class III. Moreover, statistically significant improvement was noted in ejection fraction of patents irrespective of initial class of heart failure (p<0.001) in group B patients compare to group A (p<0.09). \u0000Conclusion: In this study, the improvement of heart failure was more in patients who attained albumin level of ≥3g/dl.Therefore, in can be concluded that albumin infusion improves both subjective and objective improvement of patients with heart failure. \u0000University Heart Journal Vol. 15, No. 2, Jul 2019; 47-53","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80092352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship Between QRS Duration on ECG and LV Systolic Function by Echocardiography in Patients with STEMI STEMI患者心电图QRS持续时间与超声心动图左室收缩功能的关系
University Heart Journal Pub Date : 2019-08-18 DOI: 10.3329/UHJ.V15I2.42647
B. Hossain, M. Chowdhury, Z. Islam, R. C. Debnath, S. Banerjee, M. Bari
{"title":"Relationship Between QRS Duration on ECG and LV Systolic Function by Echocardiography in Patients with STEMI","authors":"B. Hossain, M. Chowdhury, Z. Islam, R. C. Debnath, S. Banerjee, M. Bari","doi":"10.3329/UHJ.V15I2.42647","DOIUrl":"https://doi.org/10.3329/UHJ.V15I2.42647","url":null,"abstract":"Background: Acute STEMI patients constitute a large proportion of admissions in coronary care unit and their management and prognostic implification is of immense importance. Prolonged QRS duration on electrocardiogram (ECG) has been associated with cardiac structural and functional abnormalitiesVery few studies were performed correlating QRS duration and LV systolic function in acute STEMI patients in our country. This study assessed whether QRS duration on ECG is correlated with LV systolic function measured in patients with acute STEMI. \u0000Aim of the Study: The aim of the study is to evaluate the relationship between QRS duration on ECG with left ventricular systolic function by echocardiography in patients with acute ST elevation myocardial infarction. Methods: A cross sectional observational study was conducted in the department of Cardiology in Mymensingh Medical College Hospital from November, 2016 to February, 2018 among purposively selected 235 patients with STEMI following inclusion & exclusion criteria. After detailed history, physical examination and investigations the selected patients underwent transthoracic Echocardiography to asses left ventricular systolic function applying Teichholz method. \u0000Results: Mean age of the patients 51.84±11.74 years. 135(57.45%) patients had acute anterior MI, while 98(41.70%) had Inferior MI and only 2(0.85%) had lateral MI. Mean QRS duration was 93.3 ±10.18 ms, with maximum value 125ms and minimum value 66ms. Mean left ventricular ejection fraction was 49.71%±9.87%, with maximum value 74% and minimum value 23%. QRS duration and left ventricular ejection fraction were moderate negative correlation with r= -0.611, <P = 0.001. \u0000Conclusion: The study concluded that QRS duration is negatively correlated with Left ventricular systolic function in patients with acute ST elevation myocardial infarction. \u0000University Heart Journal Vol. 15, No. 2, Jul 2019; 54-59","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80859107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of LVEF with Changing left Ventricular Morphology in Hypertrophic Cardiomyopathy 肥厚性心肌病左心室形态学变化与左心室血流动力学的评价
University Heart Journal Pub Date : 2019-05-17 DOI: 10.3329/UHJ.V15I1.41440
M. Masum, Rayhan Shahrear, Z. A. Yesmin, L. Nishat, L. Banu
{"title":"Evaluation of LVEF with Changing left Ventricular Morphology in Hypertrophic Cardiomyopathy","authors":"M. Masum, Rayhan Shahrear, Z. A. Yesmin, L. Nishat, L. Banu","doi":"10.3329/UHJ.V15I1.41440","DOIUrl":"https://doi.org/10.3329/UHJ.V15I1.41440","url":null,"abstract":"Background:Hypertrophic cardiomyopathy (HCM) is the most frequent type of cardiomyopathy. HCM is a disease of changing cardiac morphology that causes various form of cardiac dysfunction. HCM patients may remain asymptomatic and undiagnosed for a long time. If they become symptomatic, they commonly present with breathlessness, chest discomfort, and exertion. It is also responsible for the sudden cardiac death.Proper assessment of the functional status of the heart is required for proper management strategies of HCM. Objective: The objective of the study was to assess the IVS, PWT and LVEF in different cardiac phenotypes as well as to draw correlation among them. Materials and method:A descriptive cross-sectional study was undertaken on thirty-four adult Bangladeshi hypertrophic cardiomyopathy patients (thirty-one male, three female). The study was carried out in the Department of Anatomy, BSMMU. Diagnoses adult HCM patients were selected as study patients. Transthoracic echocardiography was done to assess the interventricular septal thickness (IVS), left ventricular posterior wall thickness (PWT) and left ventricular ejection fraction (LVEF). Result: The changes in the value of the left ventricular ejection fraction shows significant correlation with left ventricular posterior wall thickness,rather than the interventricular septal thickness. Conclusion:Though significant correlation between left ventricular ejection fraction and left ventricular posterior wall thickness was found, a large cohort study could be done to see the long term outcome of such correlation. \u0000University Heart Journal Vol. 15, No. 1, Jan 2019; 12-15","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"175 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90050256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Assessment of Regional Wall Motion Abnormality in Patients with Acute Anteroseptal ST Segment Elevation Myocardial Infarction 急性房间隔ST段抬高型心肌梗死患者局部壁运动异常的评价
University Heart Journal Pub Date : 2019-05-17 DOI: 10.3329/UHJ.V15I1.41443
T. A. Khan, Saiful Ahmed, Mostashirul Haque, Rasul Amin, A. Hasan, J. Arzu, Aparna Rahman, A. Zahid
{"title":"Assessment of Regional Wall Motion Abnormality in Patients with Acute Anteroseptal ST Segment Elevation Myocardial Infarction","authors":"T. A. Khan, Saiful Ahmed, Mostashirul Haque, Rasul Amin, A. Hasan, J. Arzu, Aparna Rahman, A. Zahid","doi":"10.3329/UHJ.V15I1.41443","DOIUrl":"https://doi.org/10.3329/UHJ.V15I1.41443","url":null,"abstract":"Post myocardial infarction (MI) short and long term clinical outcome is largely determined by the size of the infarcted area. It is generally assumed that as the lead involvement in the 12 lead electrocardiography (ECG) is less in anteroseptal ST segment elevation myocardial infarction (AS-STEMI), where ST segment elevation (STE) is limited to leads V1 to V3, myocardial damage is likely to be less. This study was intended to assess regional wall motion abnormality (RWMA) in acute anteroseptal STEMI patients. 90 patients with AS-STEMI admitted in between October 2012 and September 2013, were included. For each patient, a transthoracic echocardiogram (TTE) was performed within 24-48 hours of MI and was interpreted by an independent investigator blinded to the patient’s ECG data.The mean (± SD) age of the patients was 51.57 (± 12.02) years with mean (± SD) age of the patients was 52.58 (± 12.02) years with a range of 23 - 80 years. There were 91.1% male and 8.9% female. The mean (± SD) EF% was 38.80 %( ± 5.78). All the segments of left ventricle, except basal and mid inferolateral segments, were affected in anteroseptal STEMI. So, the term AS-STEMI may be a misnomer, as it implies that only the anteroseptal segments of the left ventricle are involved. This study shows that regional dysfunction in patients with AS-STEMI extends beyond the anteroseptal region and may be it is as much extensive as extensive anterior myocardial infarction. So, any patients with anterior wall involvement should be treated with utmost importance. \u0000University Heart Journal Vol. 15, No. 1, Jan 2019; 28-33","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"247 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79330231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of Heart Failure 心力衰竭的处理
University Heart Journal Pub Date : 2019-05-17 DOI: 10.3329/UHJ.V15I1.41437
Mohammad Safiuddin, H. Hoque
{"title":"Management of Heart Failure","authors":"Mohammad Safiuddin, H. Hoque","doi":"10.3329/UHJ.V15I1.41437","DOIUrl":"https://doi.org/10.3329/UHJ.V15I1.41437","url":null,"abstract":"Abstract not available \u0000University Heart Journal Vol. 15, No. 1, Jan 2019; 1-2","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90579571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Prediction of MACE by Angiographic Perfusion Score (APS) in Risk Stratification following Percutaneous Coronary Stenting in STEMI without Thrombolytic Therapy 血管造影灌注评分(APS)预测STEMI患者经皮冠状动脉支架置入术后危险分层中的MACE
University Heart Journal Pub Date : 2019-05-17 DOI: 10.3329/UHJ.V15I1.41441
K. M. Iqbal, S. Ahsan, M. M. Rahman, M. Chowdhury, Khurshed Ahmed, T. Parvin, A. Jamil, F. I. Khaled, S. Malla, Pritam Kumar Gachchhadar, Mrm Mandal
{"title":"Prediction of MACE by Angiographic Perfusion Score (APS) in Risk Stratification following Percutaneous Coronary Stenting in STEMI without Thrombolytic Therapy","authors":"K. M. Iqbal, S. Ahsan, M. M. Rahman, M. Chowdhury, Khurshed Ahmed, T. Parvin, A. Jamil, F. I. Khaled, S. Malla, Pritam Kumar Gachchhadar, Mrm Mandal","doi":"10.3329/UHJ.V15I1.41441","DOIUrl":"https://doi.org/10.3329/UHJ.V15I1.41441","url":null,"abstract":"Background: ST-elevation myocardial infarction (STEMI) is a major cause of mortality worldwide. PCI remain gold standard management of STEMI. An Angiographic Perfusion Score (APS) is a combination of TIMI Flow Grades (TFG) and myocardial perfusion (TMPG) grades before and after PCI. So it can accurately measure both epicardailand myocardial perfusion and predict major adverse cardiac events (MACE). The aim of the study is to evaluate the association of APS for determining the short term clinical outcomes after PCI in ST-segment elevation myocardial infarction without thrombolytic therapy. Methodology: This cross sectional observational study carried out among adult patients presenting STsegment elevation myocardial infarction without thrombolytic pretreatment to the cardiology department of BSMMU who underwent Percutaneous Coronary Intervention and met inclusion and exclusion criteria. This study was conducted from April 2017 to March 2018. After informed written consent data collection was carried out by using a data sheet. Calculated sample size of the study was 205. Angiogram was done by SIEMENS AXOM ARTIS machine, CD Analysis to see TFG & TMPG for calculation of APS was done by two specialist observer (Professor, Associate or Assistant Professor) MACE was observed within 30 days. Chi square test was done to see the association of APS with MACE by Statistical Package for Social Science program 20 version of computer on the basis of different variables. Results: MACE distribution of the study patients revealed that only 7.8% of the patients had MACE whereas 92.2% of the patients had no MACE among 205 patient APS score with MACE distribution of the study patients revealed that 9.3% patient of partial perfusion group and 44.4% patient of failed perfusion group had MACE but there were no major adverse cardiac event in full perfusion group of patient. The difference were statistically highly significant (p<0.05) among three groups but there were no differences in the baseline characteristics of those who had full, partial or failed perfusion of APS. Conclusion: APS which combines TFG with TMPG before and after PCI is a better discriminator of 30 day MACE than TMPG or TFG alone taken only after PCI. It can identify high risk patients who need implementation of early invasive strategies. We conclude that APS is a better predictor of MACE to take care of patient more accurately. \u0000University Heart Journal Vol. 15, No. 1, Jan 2019; 16-21","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90893266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Noninvasive Evaluation of Coronary Perfusion by Transthoracic Doppler Echocardiography in Patients with Anterior Myocardial Infarction before Coronary Intervention 经胸多普勒超声心动图无创评价前路心肌梗死患者冠状动脉介入治疗前冠状动脉灌注
University Heart Journal Pub Date : 2019-05-17 DOI: 10.3329/UHJ.V15I1.41442
S. Malla, Mostashirul Haque, D. Osmany, T. Parvin, Mohammad Safiuddin, S. Banerjee, S. Ahsan, C. M. Ahmed, K. M. Iqbal
{"title":"Noninvasive Evaluation of Coronary Perfusion by Transthoracic Doppler Echocardiography in Patients with Anterior Myocardial Infarction before Coronary Intervention","authors":"S. Malla, Mostashirul Haque, D. Osmany, T. Parvin, Mohammad Safiuddin, S. Banerjee, S. Ahsan, C. M. Ahmed, K. M. Iqbal","doi":"10.3329/UHJ.V15I1.41442","DOIUrl":"https://doi.org/10.3329/UHJ.V15I1.41442","url":null,"abstract":"Background: Transthoracic Doppler Echocardiography (TTDE) has made a breakthrough in noninvasive evaluation of coronary artery flow, especially in the distal left anterior descending coronary artery (LAD). The present study was intended to test the hypothesis whether TTDE can differentiate coronary perfusion with Thrombolysis in Myocardial Infarction (TIMI) grade 3 from TIMI grade ≤2 in patients with anterior myocardial infarction (AMI). Methods: A total of 30 consecutive patients suggestive of anterior MI including those who received thrombolysis with the potential need for Percutaneus Coronary Intervention (PCI) were enrolled in the study. The coronary perfusion was evaluated by antegrade flow visualization in distal LAD by Colour TTDE and antegrade flow velocity measured by pulsed TTDE followed by coronary angiogram for TIMI grade flow in culprit artery. The sensitivity, specificity and diagnostic accuracy were determined by comparing TTDE parameters with angiographic TIMI flow grade. Results: The antegrade distal LAD flow visualization by Color TTDE enabled differentiation of TIMI 3 from TIMI ≤2 with a sensitivity, specificity, PPV, NPV and diagnostic accuracy of 100%, 62.5%, 40%, 100% and 70% respectively. The Receiver Operating Characteristic (ROC) curve constructed to find the cut-off value for antegrade flow velocity in distal LAD in differentiating TIMI 3 from TIMI 0-2 was found to be 30.5 cm/ s with an area under the curve being 0.893, p =0.011. The antegrade flow velocity in distal LAD e” 30.5 cm/s by pulsed TTDE had a fair sensitivity (66.7%) , but had high specificity (100%) and overall diagnostic accuracy (86.7%). Conclusion: The study concluded that antegrade distal LAD flow visualization by Color TTDE can fairly differentiate TIMI 3 from TIMI ≤2 with high sensitivity, and moderate specificity and diagnostic accuracy. Additionally, the antegrade flow velocity in distal LAD by pulsed TTDE has a moderate sensitivity and high specificity to predict the angiographic TIMI flow grade. Thus, TTDE enables noninvasive differentiation of coronary perfusion in patients with anterior MI before coronary intervention. \u0000University Heart Journal Vol. 15, No. 1, Jan 2019; 22-27","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73713437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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