University Heart Journal最新文献

{"title":"Comparison of anti-thrombotic strategies using Bivalirudin, Heparin plus Eptifibatide, and Unfractionated Heparin Monotherapy for acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI): A single-center observational stu","authors":"A. G. Mostofa, T. Parvin, Mrm Mandal, P. Biswas, Goutom Chandra Bhowmik, Fysal Faruq, S. Ahsan","doi":"10.3329/uhj.v17i2.54364","DOIUrl":"https://doi.org/10.3329/uhj.v17i2.54364","url":null,"abstract":"Objective: To determine and compare the incidence of in-hospital and 30-day hemorrhagic complication and major adverse cardiac events (MACEs) as evidence of safety and efficacy using three different anti- thrombotic strategies using Bivalirudin, Heparin plus Eptifibatide (GPI: GP IIb/IIIa inhibitor), and Unfractionated Heparin (UFH) monotherapy in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI) in a tertiary care cardiac hospital. Background: UFH or Heparin plus Eptifibatide or Bivalirudin is the most commonly used antithrombotic regimen to improve peri and post-PCI clinical outcomes in a patient undergoing PCI for ACS. Among them, the most effective and optimal antithrombotic regimen for preventing ischemic complications while limiting bleeding risk in ACS patients undergoing PCI is still far from being clear. Methods: 324 ACS patients ( age >18 years and ≤75 years) who underwent PCI from May 2018 to May 2019 at UCC, BSMMU, Dhaka were consecutively enrolled in the study and were divided into three groups according to antithrombotic. The choice of Anti-thrombotic strategy was at the discretion of the operator(s) and the patient’s affordability. Group-A: 107 patients received Bivalirudin as intravenous (I/V) bolus of 0.75 mg/ kg, followed by an infusion of 1.75 mg/kg/hr up to 4 hours. Group-B: 111 patients received UFH as an I/ V bolus of 70-100 U/kg (targeted ACT: 250-300 s). Group-C: 106 patients were administered UFH plus Eptifibatide as per the standard hospital guidelines. Dual antiplatelet (DAPT) loading as Aspirin 300 mg plus P2Y12 inhibitors ( Clopidogrel 600 mg or Prasugrel 60 mg or Ticagrelor 180 mg) was given in all patients before the procedure. The maintenance dose of DAPT was continued for at least one month and patients were followed telephonically up to 30 days. The outcome measures were in-hospital and 30-day hemorrhagic complication and MACEs [death, MI, stroke, stent thrombosis and target-vessel revascularization (TVR)] Results: In-hospital outcome: Patients treated with Bivalirudin as compared with UFH had a significantly lower incidence of QMI lesions (0% vs.6%; p=0.038) and major bleeding (0% vs. 7%; p=0.021). The bleeding rate was also significantly lower in Bivalirudin arm as compared with Heparin plus GPI arm (0% vs. 6%; p=0.038). However, the incidence of cardiac death, stent thrombosis, TVR were no differences among the three groups. 30-day outcome: There was only one NQMI in the bivalirudin group as opposed to 8% in the heparin group (p=0.041). No other adverse effects were found significantly different among the study groups. Conclusion: In this perspective, observational study of ACS patients undergoing PCI in a single-center showed that Bivalirudin monotherapy is safer than other contemporary antithrombotic strategies. In terms of efficacy, Bivalirudin is non inferior to Heparin plus Eptifibatde but superior to UFH monotherapy. \u0000University Heart Journal Vol. 17, No. 2, Jul 2","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89371139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between Insulin Resistance and LVEF in non Diabetic Chronic Heart Failure Patients admitted in a Tertiary Care Hospital","authors":"Azharul Islam, M. Mahmood, Khurshed Ahmed, S. Banerjee, S. Ahsan, C. M. Ahmed, A. I. Akand, Saha Sk, Fysal Faruq, Kamruzzman Siddiki, Akm Fazlur Rahman, F. I. Khaled, S. Zaman, F. Yeasmin, P. Akter, H. Hoque","doi":"10.3329/uhj.v17i2.54365","DOIUrl":"https://doi.org/10.3329/uhj.v17i2.54365","url":null,"abstract":"Background: Insulin resistance is a well-established composite index of systemic inflammatory and metabolic disorders. A wide variety of methods like, HOMA-IR (Homeostatic model assessment insulin resistance), FGIR (Fasting glucose insulin ratio), ISI-Composite (an index of whole body insulin sensitivity), QUICKI (quantitative insulin sensitivity check index) etc are available for assessing IR. Objective: To find out the correlation between insulin resistance and LVEF in non diabetic chronic heart failure patients. Methodology: This cross sectional study was carried out in the Department of Cardiology in Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka from February, 2019 to June, 2020. Patients admitted with chronic heart failure with reduced ejection fraction were included in this study. Patients with diabetic, prediabetic and patient who did not give written informed consent were excluded in this study. Results: LVEF 25-29% was 16 patients out of which 10(66.7%) had significant insulin resistance. LVEF 30- 34% was found in 28 patients, among them 16(41.0%) had no insulin resistance. LVEF 35-39% was found in 19 patients out of which 18(46.2%) had no insulin resistance. The difference was statistically significant (p<0.05). A negative correlation (r=-0.340; p=0.006) was found between insulin resistance and LVEF. Conclusion: Majority non diabetic chronic heart failure patients had no insulin resistance. Significant negative correlation was found between insulin resistance and LVEF. \u0000University Heart Journal Vol. 17, No. 2, Jul 2021; 99-102","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89725404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Serum Vitamin-D Level with Coronary Angiographic Severity In Patients with Acute Coronary Syndrome","authors":"Kamruzzaman Siddiki, H. Hoque, Mukhlesur Rahman, F. I. Khaled, Fysal Faruq, M. Alam, A. Kabir, Sayed Nazmul Islam, Azharul Islam, S. Zaman","doi":"10.3329/uhj.v17i2.54367","DOIUrl":"https://doi.org/10.3329/uhj.v17i2.54367","url":null,"abstract":"Background: Acute Coronary Syndrome includes to a group of conditions compatible with acute myocardial ischemia and/or infarction that are usually due to an abrupt reduction in coronary blood flow. In the last decade vitamin-D deficiency as a predisposing factor for coronary artery disease is in growing interest. Prospective studies give conflicting results regarding correlation of serum vitamin D level with coronary angiographic severity in patients with acute coronary syndrome. Objective: To study the correlation between serum vitamin-D level with coronary angiographic severity in patients with acute coronary syndrome. Methodology: This cross sectional observational study was done between November 2018 and October 2019. Total 71 patients with diagnosis of first incident of acute coronary syndrome in department of cardiology, BSMMU who were underwent coronary angiogram included in this study considering the inclusion and exclusion criteria. Vitamin D was measured by chemiluminescent immunoassay after collection of venous blood at Department of Biochemistry, BSMMU. Angiographic severity was assessed by using Gensini score. Statistical analyses were carried out by using the Statistical Package for Social Sciences version 23.0 for Windows (SPSS Inc., Chicago, Illinois, USA). Results: The mean age was found 55.9±10.7 years with a range from 36 to 82 years. Majority (83.1%) patients were male. The male-female ratio was 4.9:1. Thirty (42.3%) of the patients had STEMI, 28(39.4%) had NSTEMI and 13(18.3%) had unstable angina. Negative correlation (r=-0.479; p=0.001) was found between serum vitamin D level and Gensini score in patients with acute coronary syndrome. Conclusion: In this study found that serum vitamin-D level is inversely correlated with angiographic severity in patients with acute coronary syndrome. \u0000University Heart Journal Vol. 17, No. 2, Jul 2021; 103-107","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88611510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Context of StichTrial: Viable or not viable Does it matter before revascularization?","authors":"C. M. Ahmed, A. Sultan","doi":"10.3329/uhj.v17i2.54361","DOIUrl":"https://doi.org/10.3329/uhj.v17i2.54361","url":null,"abstract":"Abstract not available \u0000University Heart Journal Vol. 17, No. 2, Jul 2021; 79-80","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85892221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of left Ventricular Longitudinal Function in Different Hypertensive Left Ventricular Geometry","authors":"Md Nur Uddin Tareq, C. M. Ahmed, S. Mahmud, K. Haque","doi":"10.3329/uhj.v17i1.50877","DOIUrl":"https://doi.org/10.3329/uhj.v17i1.50877","url":null,"abstract":"Background: Hypertension remains as the major risk factor for cardiovascular diseases. Hypertensive left ventricular hypertrophy was shown to be associated with increased morbidity and mortality. Left ventricular radial function (Ejection fraction) tends to remain normal in hypertensive patients, particular attention should be given to longitudinal function along with diastolic function. Left ventricular longitudinal function may vary across different hypertensive LV geometry with different prognosis. \u0000Results: Of the total 214 study subjects, 109 (50.9%) were Cases and 105 (49.1%) were Controls. The mean ages of cases and controls were 52.66 (± 10.96) and 50.21 (± 10.91) years respectively. Left ventricular ejection function (LVEF) was almost identical in both groups [mean LVEF in case 68.7 % (± 6.9) Vs control 68.7(± 5.4), (p 0.947)]. Among the cases 43% had concentric hypertrophy (CH), 20% had eccentric hypertrophy (EH), 20% had concentric remodeling (CR), while normal geometry constituted the least 16.5%. Mean systolic mitral annular velocity (Vs) and mean early diastolic velocity (Ve) assesed by pulse wave tissue doppler imaging were observed to be significantly decreased in cases compared to their control counterpart (11.46 ± 1.26 vs. 15.41 ± 1.00 cm/sec, p < 0.001 and 13.80 ± 2.37 vs. 16.76 ± 2.67 cm/sec, p < 0.001. There was significant reduction of Vs in concentric hypertrophy and eccentric hypertrophy (11.31 ± 1.41 and 12.27 ± 2.14). (p <0.001 and <0.005). Among cases 55 (50.5%) and among controls 17 (16%) had diastolic dysfunction. Mean systolic mitral annular velocity (Vs) in patients with diastolic dysfunction (12.42 ± 1.90 cm/sec) was significantly lower than that in patients without diastolic dysfunction (13.86 ± 2.30 cm/sec) (p < 0.001). \u0000Conclusion: Radial function (LVEF) remains normal in patients with systemic hypertension as compared to controls. LVH is common among hypertensive and concentric hypertrophy is the commonest geometry. LV longitudinal systolic function as assessed by systolic mitral annular velocity (Vs) by DTI was significantly reduced in hypertensives and CH is the most severely affected with EH at intermediate risk. Diastolic dysfunction is also common but almost alaways accompanied by impairment of LV longitudinal systolic function. \u0000University Heart Journal Vol. 17, No. 1, Jan 2021; 31-37","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"94 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86647862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of GRACE Risk Score with Angiographic Severity of Coronary Artery Disease in Patients with Non ST-elevation Acute Coronary Syndrome","authors":"Md. Estakur Rahman, -. Mohammad Safiuddin, S. Habib, C. M. Ahmed, S. Banerjee","doi":"10.3329/uhj.v17i1.50879","DOIUrl":"https://doi.org/10.3329/uhj.v17i1.50879","url":null,"abstract":"Background: Due to the wide spectrum of risk for death and recurrent events among patients with NSTE-ACS, management guidelines emphasise the importance of early risk stratification. In addition to prognostic assessment, predicting the anatomical extension of coronary artery disease is potentially useful for clinical decision. The aim of the study is to determine whether the GRACE risk score correlates with the angiographic extent and severity of coronary artery disease in patients with non ST-elevation ACS \u0000Methods: A total of 50 patients with non-ST-elevation acute coronary syndrome were enrolled to the study. Based on the GRACE risk score classification system, the patients were divided into low (<108), intermediate (109-140), and high (>140) risk groups. All patients underwent coronary angiography within five days after admission. The severity of the coronary artery disease was assessed by Gensini score. Relation between Grace score and Gensini score was evaluated. \u0000Results: Mean Gensini score were 12.20 ± 13.60, 34.52 ± 13.50 and 48.41 ± 14.56 in low group, intermediate group and high GRACE risk group respectively and the difference of mean Gensini score was statistically significant (p<0.001). A GRACE score of 135 was identified as the optimal cut-off to predict severe CAD (sensitivity = 82.4% and specificity = 75.8%). In our study correlation co-efficient between GRACE risk score and Gensini score was r=0.66 (p<0.001). \u0000Conclusion: The study demonstrates that the GRACE risk score has significant positive correlation with coronary artery stenosis in patients with non-ST-elevation acute coronary syndrome. \u0000University Heart Journal Vol. 17, No. 1, Jan 2021; 38-41","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91107622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relying on ST Segment Depression alone to Predict Ischemic Heart Disease- How Far We can Go ?","authors":"M. Alam, M. M. Rahman, T. Parvin, Khurshed Ahmed, S. Habib, Md Fakhrul Islam Khaled, Md. Azharul Islam, Md Ahasanul Kabir Shahin, Kamruzzaman Siddiki, Md Al Amin","doi":"10.3329/uhj.v17i1.50874","DOIUrl":"https://doi.org/10.3329/uhj.v17i1.50874","url":null,"abstract":"Introduction: Ischemic heart disease (IHD) or coronary artery disease (CAD) has become predominant cause of death across the world and frequently stable angina, which is the most common presentation of this disease, gives hard time to reach a proper diagnosis due to duality of non-invasive testing. While Exercise Treadmill Test (ETT) is an inexpensive non-invasive modality which may have many output depending on method of interpretation, ST segment depression is much utilized but traditionally less perfect than available treadmill scores. We have compared its accuracy to Duke Treadmill Score (DTS), Simple Treadmill Score (STS) and Cleveland Clinic Score (CCS) among Bangladesh people to generate a local insight. \u0000Objective: To estimate and compare accuracy of ST segment response, DTS, Simple Treadmill Score and Cleveland Clinic Score to predict CAD. \u0000Method: In a cross-sectional study total 130 patients who had visited at a medical university with stable chest pain were selected according to predefined inclusion and exclusion criteria over one year. After taking proper history and physical examination their ETT report and Coronary Angiogram (CAG) finding, which were done according to indication defined by their consultants. ETT interpretation as ST segment response and treadmill scores were compared with gold standard test for CAD that is CAG. Accuracy of STdepression and treadmill scores were calculated by the formula “Accuracy = TP+TN / Total Sample”. \u0000Result: Among the total sample (n=130) male and female were 93 & 37, respectively. Nearly half of male sample fell into 5th decade and around same portion of female sample was in 4th decade. About 58%, 28% & 14% patients came with typical, atypical & non-cardiac chest pain. As calculated with above mentioned formula accuracy of ST segment response alone to diagnose IHD came about 68.4% (p value 0.004). Similarly DTS, STS and CCS had 83.3%, 83.9% and 77.2% accuracy, respectively (p value 0.000). \u0000Conclusion: During ETT relying on ST segment depression alone to diagnose CAD is significantly less accurate than treadmill scores namely, Duke Treadmill Score, Simple treadmill Score or Cleveland Clinic Score. Applying any of these treadmill scores during exercise test interpretation can identify ischemic heart disease patients with more accuracy. \u0000University Heart Journal Vol. 17, No. 1, Jan 2021; 10-15","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89773019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiographic Assessment of the Effect of Mitral Stenosis Severity on Left Ventricular Systolic Function Using Isololumic Myocardial Acceleration","authors":"Md Hasanul Islam, D. Adhikary, T. Parvin, R. Barman, Mahbubur Rahman, Md. Ashraf Uddin Sultan, M. Chowdhury, Md. Harisul Hoque","doi":"10.3329/uhj.v17i1.50880","DOIUrl":"https://doi.org/10.3329/uhj.v17i1.50880","url":null,"abstract":"Background: Isovolumic myocardial acceleration (IVA) is a new tissue Doppler parameter in the assessment of systolic function of both right and left ventricles. It remains unaffected with the changes in pre-and after load with in the physiological range. With the advent of newer parameter like IVA, better assessment are naturally expected. Thus it creates a fertile ground where upon many studies are being done as it chosen here. The aim of study was to assess the effect of MS severety on LV systolic function using IVA. \u0000Methods: In this cross sectional study, considering all ethical issues, data were collected from 96 patient (Isolated mitral stenosis and mitral valve area <2cm2) and 32 healthy control subjects. In addition to standard echocardiographic methods TDI (tissue Doppler imaging) were performed to assess LV function in all participants. \u0000Results: This study showed a clear female preponderence (76%) of mitral stenosis and most of them belonging to age group 21-39 years. All TDI derived LV systolic (IVV, Sm and IVA) velocities were significanty decreased in patients with mitral stenosis, compared to the healthy control (P<.001, for all). However IVA was not different when the degree of MS was evaluated (P=.056). In addition IVA was not correlated with MVA (r=+0.196. P= 0.056). \u0000Conclusions: Isovolumic myocardial acceleration was more accurate and consistent than conventional echocardiography in assessing subclinical left ventricular systolic dysfunction, IVA showed that left ventricular function is impaired with mitral stenosis regardless of severety of the disease. So this new echo parameter can be a good supplement to the existing 2D scoring system to detect systolic dysfunction in rheumatic mitral stenosis. \u0000University Heart Journal Vol. 17, No. 1, Jan 2021; 42-46","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82841652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between Abnormal Signal-Averaged ECG and Left Ventricular Ejection Fraction in Patients of Acute Myocardial Infarction within Seven Days of Sustaining the Infarction.","authors":"Mohammad Abdul Malek, S. Iqbal, A. Haque, Sayeda Aleya Sultana, Md Wali ur Rahman, M. M. Rahman","doi":"10.3329/uhj.v17i1.50873","DOIUrl":"https://doi.org/10.3329/uhj.v17i1.50873","url":null,"abstract":"Objective: This study sought to evaluate the correlation of left ventricular ejection fraction (LVEF) with Signal – Average Electrocardiogram (SAECG) in patient with acute myocardial infarction. \u0000Background: Post MI risk stratification is still a debatable issue. Appropriate investigation to ascertain the patient at risk of sudden cardiac death is sometimes difficult. Abnormalities in the SAECG have been determined to be independent predictors of risk of developing ventricular arrhythmias in patients convalescing from myocardial infarction. Correlation of LVEF with SAECG will identify the small group of patient at risk of fatal arrhythmia. \u0000Method: This observational study was carried out in the cardiology center, Combined Military Hospital, Dhaka cantonment during the period of January 2010 to January 2011. Patient with first acute myocardial infarction within 7 days of sustaining acute myocardial infarction were included in the study. All three parameters of SAECG (Total QRS duration, Low Amplitude Signal (LAS) under 40μvolt, Root - mean -square (RMS) voltage of last 40 msec) were recorded, and basing on the results, patients were grouped into normal or abnormal SAECG. \u0000Result: A total of 106 patients of acute MI were studied. Mean age of the patients were 54(SD±10.5) years (range 34 to 90 years). Only 13(12%) patients were female with male to female ratio of 7.15:1. 32% patients were thrombolysed & abnormal SAECG was more in patients who were thrombolysed (p value<0.05) but logistic regression analysis showed no significant association. Smoking had significant association with abnormal SAECG by univariate analysis (p value<0.05) but logistic regression analysis showed no significant association with smoking and sex (p value >0.05). 46% patients had inferior/inferoposterior myocardial infarction. Abnormal SAECG was more among patients with inferior MI (p <0.05). Mean LVEF was 45.81% (SD±9.68). Correlation of LV function was assessed by both Pearson’s correlation and Ç2 test but no significant association was seen. Logistic regression analysis showed the similar result. \u0000Conclusion: In our study, no correlation was found between abnormal signal-averaged ECG and left ventricular ejection fraction following acute myocardial infarction. Further large, multi center study with more selective variables is required to find out any association of SAECG and LV ejection fraction. \u0000University Heart Journal Vol. 17, No. 1, Jan 2021; 3-9","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73621259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Myocardial Infarction in a Young Lady with Mitral Stenosis – Uncommon Presentation of a Common Problem","authors":"A. Bhuiyan, A. Hasan, M. M. Rahman, Partha Pratim Saha","doi":"10.3329/uhj.v17i1.50886","DOIUrl":"https://doi.org/10.3329/uhj.v17i1.50886","url":null,"abstract":"Chronic rheumatic heart disease is the major contributor of valvular heart disease in this subcontinent. It can affect all the four valves. Among them mitral valve is affected most of the time. Involvement of the mitral valve could be presented in various nonspecific way like chest pain, palpitation, shortness of breath, difficulty in swallowing, change in voice and so on. There are few causes behind the chest pain. Myocardial infraction is one of the important cause. \u0000University Heart Journal Vol. 17, No. 1, Jan 2021; 76-78","PeriodicalId":23424,"journal":{"name":"University Heart Journal","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78814534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}