Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki最新文献

{"title":"Using the ASTER GDEM v.2 Global Digital Elevation Model to Identify Areas of Possible Activation of Karst Processes in the Arkhangelsk Region (Russia)","authors":"E. V. Polyakova, Y. Kutinov, A. Mineev, Z. Chistova, T. Belenovich","doi":"10.26907/2542-064x.2021.2.302-319","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.2.302-319","url":null,"abstract":"The possibility of applying the method of detecting drainless depressions, which is used in hydrological correction of the digital elevation model, to identify areas of probable activation of the karst processes in the territory of the Arkhangelsk region was considered. This approach is especially relevant for northern forested territories subjected to continuously increasing anthropogenic activity. Errors (depressions) eliminated by the hydrological correction procedure are not always false. They can be natural landforms, especially in karst areas. Hydrological correction of the digital elevation model of the Arkhangelsk region (based on ASTER GDEM v.2) was performed. A vector layer of depressions in the region was obtained. The density of drainless depressions per unit area was calculated. The resulting map showing the density of drainless depressions was compared with the distribution of karst rocks in the Arkhangelsk region. It was found that the areas of maximum open karst development are associated with a low density of drainless depressions. The highest density of drainless depressions occurs in the territory with carbonate-covered and buried karst.","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"72 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83916758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modern Methods of Preclinical Anticancer Drug Screening Using Test Systems Based on Cell Cultures","authors":"K. Kitaeva, A. A. Rizvanov, V. Solovyeva","doi":"10.26907/2542-064x.2021.2.155-176","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.2.155-176","url":null,"abstract":"","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"6 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82094835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Сladocera (Branchiopoda, Crustacea) in the Taphocenoses of Lakes in the Pechora River Delta (Russia)","authors":"N. Nigmatullin, G. Nigamatzyanova, E. A. Valieva, L. Frolova","doi":"10.26907/2542-064x.2021.3.527-537","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.3.527-537","url":null,"abstract":"This paper presents the results of the hydrochemical, hydrobiological, and paleolimnological studies of 17 Arctic lakes in the Pechora River delta. Water samples and surface sediments were collected during the 2020 summer expedition to the Nenets State Nature Reserve. Based on the chemical composition of their waters, the studied lakes belong to the chloride class, sodium group II. Overall, they are characterized by shallow depths typical of this region, low mineralization (below 200 mg/L) and water hardness, as well as high dissolved oxygen levels. To assess the ecological status of the lakes, cladocerans and their subfossil remains, which have been widely recognized as reliable indicators for tracking long‐term changes in the development of freshwater ecosystems, were analyzed. A total of 23 cladoceran taxa were identified. The dominant species were Bosmina longispina (Leydig, 1860) and Chydorus cf. sphaericus (Müller, 1776) – either of these species, often displacing each other, prevailed in the lakes. Other cladoceran species were low-abundant and found sporadically: Sida crystallina (Müller, 1776), Pleuroxus uncinatus (Baird, 1850), Coronatella rectangula (Sars, 1862), and Bythotrephes longimanus (Leydig, 1860). The study also reports the first finding of Rhynchotalona latens (Sarmaja-Korjonen, Hakojarvi and Korhola, 2000), a rare glacial relict species with a narrow distribution range, in this region of Russia. The zoogeographical analysis of the data obtained on the identified taxa showed that species typical of the Palearctic and Holarctic zones prevail in the cladoceran communities under study.","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"43 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74100808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Features of Albendazole Determination and Dynamics of Its Decomposition in Biological Material","authors":"V. K. Shormanov, D. P. Shcherbakov, S. Garmonov","doi":"10.26907/2542-064x.2021.2.209-220","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.2.209-220","url":null,"abstract":"Albendazole ([5-(propylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester) is a benzimidazole derivative drug that has anthelmintic activity and is especially effective against various nematodes. Along with pronounced pharmacological action, this compound is toxic to humans. Cases of poisoning with this substance and other benzimidazole derivatives are not uncommon. Despite the active use of albendazole in medical practice and its toxicity, many questions of the chemical and toxicological analysis of albendazole remain practically unexplored. In this regard, it is advisable to study albendazole in chemical and toxicological terms. This paper aims to analyze the determination and dynamics of albendazole decomposition in biological material. Acetone was used as a chemical agent for albendazole isolation from the liver as a biomaterial. Purification of the obtained extracts was carried out sequentially in a column (190 × 11 mm) of silica gel L 40/100 μm (eluent – acetone-methylene chloride (9:1)) and by liquid-liquid extraction. The methods of thin-layer chromatography (TLC), high-performance liquid chromatography combined with tandem mass spectrometry (HPLC-MS/MS), UV spectrophotometry were used for identification. The quantitative content of the analyte was determined using UV spectrophotometry by the absorption of the dimethylformamide (DMF) medium at 301 nm. The level of albendazole extraction from the biomaterial was 85–88%.","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"26 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74857441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Specific Antibodies against Binase: Preparation and Application","authors":"V. Vershinina, E. Dudkina, V. Ulyanova, V. A. Kalashnikov, O. Ilinskaya","doi":"10.26907/2542-064x.2021.4.557-568","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.4.557-568","url":null,"abstract":"","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"35 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75129566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Problem of Dating the Kuyeda-Klyuchiki Section – a Unique Locality of Permian Vertebrates (Perm Region, Russia)","authors":"A. Bakaev, V. V. Bulanov, I. Ilaltdinov, D. Kozhanov, G. Ponomareva, I. Khopta","doi":"10.26907/2542-064x.2021.3.444-465","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.3.444-465","url":null,"abstract":"The Kueda-Klyuchiki locality of Permian vertebrates located in the south of the Perm Region in the Kuedinsky District was discovered in 2005 and quickly became known among paleontologists. The locality contains a rich complex of exceptionally preserved plants and vertebrates (fish, amphibians, and reptiles). Their remains are confined to limestones of various textures, which form two bone-bearing beds in the section of the quarry. However, the age of rocks remains a controversial issue. This research aims to analyze and compare various stratigraphic markers and discuss a number of existing stratigraphic inconsistencies in an attempt to arrive at a general conclusion about the age of the locality. According to geological survey data on a scale of 1:200 000, the Buraevo Sequence (Sheshmian Formation, Ufimian Stage) was identified in the territory of the quarry. At the boundary of the Sheshmian and Belebey Formations, a mineralogical “boundary” is observed, which is manifested in a decrease","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"12 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72855282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Permian Palaeotemperature Values Proposed for Continental Red-Bed Deposits of the Tambach Formation at the Bromacker Section","authors":"F. Scholze, A. Pint","doi":"10.26907/2542-064x.2021.3.338-350","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.3.338-350","url":null,"abstract":"A variety of formulas can be found in the literature to convert geochemical data into absolute palaeotemperatures. In the present study, we test a formula for calculating the Early Permian (Artinskian) palaeotemperatures based on major element values from continental red-bed deposits of the Tambach Sandstone Member (Tambach Formation, Rotliegend Group) in Germany. The geochemical data used herein were extracted from a previous study on the Bromacker section. Applying the literature-based dataset constitutes the first approach aimed to a better understanding of certain local palaeoclimate aspects (i.e., mean annual temperature) and can be easily expanded to wider stratigraphic and palaeogeographic ranges through future studies.","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"44 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77529200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamics of the Borders of Phenological Seasons in the East of the Russian Plain (Kirov, Russia)","authors":"T. Shikhova, Kirov Russia Fur Farming, A. Soloviev","doi":"10.26907/2542-064x.2021.2.289-301","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.2.289-301","url":null,"abstract":"Using the phenological database covering the period of 1961–2019 for Kirov (58°36' N, 49°40' E), the regional features of changes in the seasonal rhythms were analyzed. Mean values were calculated for 1981–2010. Additional types of seasonal rhythms with parameters deviating from the mean values by more than ±2σ were identified. The normal onset of spring, summer, and autumn was more characteristic of the 2000s (50–70%), while the anomalous seasons (with the onset dates and duration deviating significantly from the norm) prevailed in 1991–2000 and 2010–2019, respectively. The trend of variability in the ratio of phenological seasons (shorter winter and spring, longer summer and autumn) began in the middle of the 20th century and has persisted so far. In the last 30 years, compared with the base period of 1961–1990, winter and spring have begun later, but the onsets of summer and autumn have taken place earlier. The duration of winter and spring has kept decreasing. Summer has lengthened slightly. Autumn has become significantly longer. A negative correlation was established between the durations of autumn and winter ( r = –0.65), autumn and spring ( r = –0.61). The revealed phenological trends of the 21st century (the shift in the onset of the seasons, as well as the change in their duration and the increase in the amplitude of their time parameters) have been consistent with the modern restructuring of the climate regime. The data obtained on the dynamics of the natural seasons are important for assessing the response of natural ecosystems in the region to weather and climate fluctuations.","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"34 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90819005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of New Inhibitors of the Kinase Activity of CDK2 and CDK9 by Molecular Modeling and High-Efficiency Screening","authors":"G. Andrianov, I. Serebriiskii","doi":"10.26907/2542-064x.2021.4.543-556","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.4.543-556","url":null,"abstract":"","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72521443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"About the Age of Fossil Flora of the Kygyltasian Regional Stage of the Upper Paleozoic in the Verkhoyansk Region, Northeastern Russia","authors":"L.G. Porokhovnichenko, R. Kutygin, A. Kilyasov","doi":"10.26907/2542-064x.2021.3.430-443","DOIUrl":"https://doi.org/10.26907/2542-064x.2021.3.430-443","url":null,"abstract":"The Kygyltasian Regional Stage is widespread throughout the Verkhoyansk Region, where it reflects a large transgressive-regressive cycle of the Verkhoyanian terrigenous sedimentation. Over the years, a huge amount of material has been accumulated on biostratigraphic division, facies features, and paleontological characteristics of this large stratigraphic unit, but its age is still debatable. The main fossils in the upper part of the Kygyltasian Regional Stage are higher plants, the remains of which were studied in the last century using outdated taxonomy. This study is devoted to revision of the collection of fossil plants from the type locality of the Kygyltasian Regional Stage (Western Verkhoyanie) in order to clarify the taxonomic composition and the age of the Upper Kygyltasian floristic association. The dominant cordaite leaves in the association were studied using the morphological and microstructural methods. This made it possible to clarify the previous paleontological definitions of the genus Noeggerathiopsis and bring them in line with modern taxonomy. The species Noeggerathiopsis heteroclitus Tolstych and N. khorokytica Tolstych were validated for type specimens. The following species were identified from the Upper Kygyltas Subformation of the Khorokyt section: Cordaites heteroclitus (Tolstych), C. cf. neuburgae Gluchova, C. cf. zalesskyi Durante, C. krychtofovichii (Radczenko), Cordaites ? khorokytica (Tolstych), Cordaites sp. sp. sp. sp. Rufloria ( Praerufloria ) Sphenophyllum cf. Sphenophyllum ? sp., Sphenopteris sp., Paracalamites sp. Based on the results of the study, the Upper Kygyltasian floristic association of the Western Verkhoyansk Region was compared with floristic associations of the Alykaeva Formation (Kuzbass) and the Upper Kata Subformation (Tunguska basin). From the above, the Late Carboniferous age of the upper part of the Kygyltasian Regional Stage follows. The results obtained are in good agreement with the correlation of the Verkhoyanian Carboniferous-Permian deposits for marine invertebrates.","PeriodicalId":23418,"journal":{"name":"Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki","volume":"20 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72753414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}