Nigerian Journal of Life Sciences (ISSN: 2276-7029)最新文献

Comparative Study on the Phytometabolites, in vitro Antiplasmodial Activity and Cytotoxicity of Stem Bark Extracts of Annickia affinis (Exell) Versteegh & Sosef and Annickia chlorantha (Oliv.) Setten & PJ. Mass 黄花水仙(Annickia affinis, Exell)和黄花水仙(Annickia chlorantha, Oliv.)茎皮提取物植物代谢物、体外抗虫活性和细胞毒性的比较研究Setten & PJ。质量

Nigerian Journal of Life Sciences (ISSN: 2276-7029) Pub Date : 2023-06-13 DOI: 10.52417/njls.v12i2.355

PJ. Mass, D. Sahal

{"title":"Comparative Study on the Phytometabolites, in vitro Antiplasmodial Activity and Cytotoxicity of Stem Bark Extracts of Annickia affinis (Exell) Versteegh & Sosef and Annickia chlorantha (Oliv.) Setten & PJ. Mass","authors":"PJ. Mass, D. Sahal","doi":"10.52417/njls.v12i2.355","DOIUrl":"https://doi.org/10.52417/njls.v12i2.355","url":null,"abstract":"The similar-looking Annickia affinis and Annickia chlorantha are two closely related species of the genus Annickia that are difficult to tell apart. Literature to date has jointly referred to both as Enantia chlorantha. Amongst the many pharmacologic benefits ascribed to E. chlorantha, is its usefulness in the management of malaria. Given the closeness of both species, there is the likelihood of swapping one for another in the market of herbal drugs. This study thus set out to compare the phytometabolites, antiplasmodial activity and cytotoxicity of both species. E. chlorantha is known to be dominated by protoberberine alkaloids which are thought to confer it with its antiplasmodial property. Indeed, TLC metabolite fingerprinting of methanol and water stem bark extracts of both species revealed the presence of protoberberine alkaloids. However, these alkaloids were more abundant in A. affinis as compared to A. chlorantha. This was corroborated by the stark >2.82 fold difference in antiplasmodial IC50 of the respective methanol extracts being <0.78 µg/ml for A. affinis versus 2.2 µg/ml for A.chlorantha. Interestingly the selectivity indices for A. affinis (22.7) and A. chlorantha (24.3) determined using human hepatoma cell line were only marginally different. In conclusion, our study suggests that although both plants may be useful for managing malaria, consumers may get better and faster antimalarial relief with A. affinis.","PeriodicalId":233674,"journal":{"name":"Nigerian Journal of Life Sciences (ISSN: 2276-7029)","volume":"151 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121610065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Application of Myco-Fabricated Silver Nanoparticle in the Adsorption of Malachite Green and Trypan Blue from Aqueous Solution 菌制纳米银在吸附孔雀石绿和台锥蓝中的应用

Nigerian Journal of Life Sciences (ISSN: 2276-7029) Pub Date : 2023-06-13 DOI: 10.52417/njls.v12i2.354

Chioma Augusta, Bright Obidinma, Dokubo, Chinweike Unoma

{"title":"Application of Myco-Fabricated Silver Nanoparticle in the Adsorption of Malachite Green and Trypan Blue from Aqueous Solution","authors":"Chioma Augusta, Bright Obidinma, Dokubo, Chinweike Unoma","doi":"10.52417/njls.v12i2.354","DOIUrl":"https://doi.org/10.52417/njls.v12i2.354","url":null,"abstract":"The study was undertaken to assess the application of myco-fabricated silver nanoparticles in the adsorption of Malachite green and Trypan blue from an aqueous solution. The cell biomass suspensions of fungal endophytes isolated from the leaves of Mannihot esculenta and Carica papaya were used in the silver nanoparticles. The method involved in nanoparticles characterization, decolourization and adsorption treatment efficacy used UV-spectroscopy FT-IR, XRD and SEM, spectrophotometric analysis and phytotoxicity testing. The result revealed that the endophyte strains PDA 1 and PDA 2 were identified as Aspergillus niger and Aspergillus fumigatus. There was colour change from colourless to dark brown revealing the biogenic synthesis of silver nanoparticles due to the formation of clumps after 24 hr. The peaks observed in FT-IR spectra reflect the role of metabolites (functional groups) which act as capping and reducing agents. The UV-Vis spectral result showed the maximum peak of PDA 1 to be 620 nm at 0.933 absorbance while that of PDA 2 were 300 nm and 450 nm at 0.684 absorbance revealing the surface plasmon resonance. The XRD peaks of the nanoparticles were clearly distinguishable and broad indicating an ultra-fine nature. The microscopic characterization of PDA 1 and PDA 2 showed the presence of flake type, a smooth and irregularly shaped granulated compact powder with bright facets. The results of the decolourization profile showed that the adsorption efficiencies of both dyes were significantly concentration and time-dependent (P < 0.05). These findings suggest the potential of these nanoparticles in the environmental remediation of harmful dyes","PeriodicalId":233674,"journal":{"name":"Nigerian Journal of Life Sciences (ISSN: 2276-7029)","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122003152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the Gastro-protective Potentials of Methanol Leaf Extract of Nymphaea lotus on Induced-Gastric Ulceration in Wistar Rats 莲花甲醇叶提取物对Wistar大鼠胃溃疡的保护作用

Nigerian Journal of Life Sciences (ISSN: 2276-7029) Pub Date : 2023-06-13 DOI: 10.52417/njls.v12i2.352

M. Aliyu, M.S. Abdulrauf, A. I. Ganiyu

{"title":"Evaluation of the Gastro-protective Potentials of Methanol Leaf Extract of Nymphaea lotus on Induced-Gastric Ulceration in Wistar Rats","authors":"M. Aliyu, M.S. Abdulrauf, A. I. Ganiyu","doi":"10.52417/njls.v12i2.352","DOIUrl":"https://doi.org/10.52417/njls.v12i2.352","url":null,"abstract":"Nymphaea lotus is a plant used traditionally for the treatment of many ailments including gastric ulcer without any scientific validation of its pharmacological action and safety. This study was undertaken to evaluate the possible gastro-protective potential of methanol extract of N. lotus leaves on gastric ulcers induced by different ulcerogens. Thirty rats (160-180 g) were divided into five groups: Group 1 was the normal control, group 2 was negative control, group 3 was administered 25 mg/kg Omeprazole (standard drug), groups 4, 5 and 6 were administered 200, 400 and 600 mg/kg methanol extract of N. lotus leaves, respectively. After two weeks of oral administration, gastric ulcer was induced in all the rats except group 1 using various ulcerogens such as 95% ethanol, indomethacin and hypothermic stress to access the gastro-protective potential of the extract. Phytochemical and anti-microbial analyses of the freshly prepared extract were carried out followed by histological studies of the gastric tissues. Nymphaea lotus leaves extract significantly (p<0.05) prevented peptic ulcers in a dose-dependent manner. The extract at 600 mg/kg showed a protective effect comparable to that of Omeprazole. Microorganisms (Klebsiella pneumonia, Escherichia coli, Staphylococcus aureus, Salmonella typhi, Aspergillus niger and Pseudomonas aeruginosa) tested in this study were inhibited by the methanol extract. The above findings indicate that methanol extract of Nymphaea lotus leaves has gastro-protective activities. ","PeriodicalId":233674,"journal":{"name":"Nigerian Journal of Life Sciences (ISSN: 2276-7029)","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129029031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antiepileptic and antioxidant evaluation of methanol extract of Moringa oleifera Lam Seed 辣木籽甲醇提取物的抗癫痫及抗氧化作用评价

Nigerian Journal of Life Sciences (ISSN: 2276-7029) Pub Date : 2023-06-13 DOI: 10.52417/njls.v12i2.356

E. O. Oghama, E. O. Gabriel, O. Timothy

{"title":"Antiepileptic and antioxidant evaluation of methanol extract of Moringa oleifera Lam Seed","authors":"E. O. Oghama, E. O. Gabriel, O. Timothy","doi":"10.52417/njls.v12i2.356","DOIUrl":"https://doi.org/10.52417/njls.v12i2.356","url":null,"abstract":"The present study was to investigate the antiepileptic and in vivo antioxidant effects of methanol seed extract of Moringa oleifera Lam (MSEMO). Mice of both sexes, weighing 25-35 g, were randomly divided into five groups of five each. The groups represented by control (distilled water), 0.5 mg/kg phenobarbitone, 100, 200 and 400 mg/kg MSEMO. Treatment was administered to the groups prior to inducement with epilepsy using graded doses of 100, 200 and 400 mg/kg of MSEMO as well as 0.5 mg/kg of phenobarbitone. Epilepsy was induced by passing a current of 50 Amps for 2 sec using an electro-convulsiometer with the aid of two electrodes clipped to the earlobes of the mice and careful observation was carried out to check for the inhibitory effect of the extract. At the end of the three weeks experimental period, the brains of the mice were taken, homogenized and the effects of the extract were tested on nitrite, malondialdehyde (MDA) and endogenous antioxidants. The extract significantly, (P< 0.05), showed the most potent protective effect against epilepsy at 200 and 400 mg/kg concentrations. Reduction in catalase level was complimented by 100 and 200 mg/kg of MSEMO. Similarly, that of glutathione peroxidase was complimented by 100, 200 and 400 mg/kg of MSEMO. Superoxide dismutase showed the most potency among the endogenous antioxidants used in the study, with no significant difference, P> 0.05, in relation to the control (2.39±0.02). The study showed that MSEMO will be efficacious as an antiepileptic drug","PeriodicalId":233674,"journal":{"name":"Nigerian Journal of Life Sciences (ISSN: 2276-7029)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123981239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HEAVY METALS AND POLY AROMATIC HYDROCARBON CONTAMINANTS IN SMOKED AND FRESH CLARIAS GARIEPINUS 烟熏和新鲜鱼中重金属和多环芳烃的污染

Nigerian Journal of Life Sciences (ISSN: 2276-7029) Pub Date : 2022-12-11 DOI: 10.52417/njls.v6i2.329

F. Osuala, M. Igwo-Ezikpe

{"title":"HEAVY METALS AND POLY AROMATIC HYDROCARBON CONTAMINANTS IN SMOKED AND FRESH CLARIAS GARIEPINUS","authors":"F. Osuala, M. Igwo-Ezikpe","doi":"10.52417/njls.v6i2.329","DOIUrl":"https://doi.org/10.52417/njls.v6i2.329","url":null,"abstract":"This study investigated the level of heavy metals and poly aromatic hydrocarbon (PAH) concentrations in fresh and smoked African catfish, Clariasgariepinus from a cultured system in Lagos, Nigeria. A total of ten randomly selected life specimens of Clariasgariepinus were collected from the Marine Science Department (Aquaculture unit) University of Lagos and smoked in a 44 gallon smoking kiln for four hours. The heavy metals content was determined using FAO / SIDA, 1983 method while PAH was analyzed using gas chromatography mass spectrometry (GC MS). The results of fresh fish samples obtained were compared withnonsmoked fish samples. Heavy metals and PAHs were detected in both samples at varying concentration. However, it was observed that there was higher concentration cadmium, lead, and zinc in smoked fish though not significantly (P < 0.05) different from that in fresh fish whereas iron and copper were insignificantly (P > 0.05) higher in fresh fish. Naphthalene, fluorene, phenanthrene, anthracene, and benzo (g,h,i) perylene} were higher in the smoked fishes though Naphthalene, and anthracene were significantly (P < 0.05) higher in smoked fishes than fresh fishes. The maximum concentration of lead was 0.0492 mg/kg that is higher than the EPA safety limit (0.001 mg/kg) while 2 methylnaphthalene concentration was highest in the smoked fishes with a mean value of 4.13 mg/kg. The statistical analysis using one way ANOVA showed that there was significant (P < 0.05) differences in the heavy metals and PAH content in the fresh and smoked fish. This study suggests that smoked fish have higher concentrations of heavy metals and poly aromatic hydrocarbons which might pose a health risk to humans when consumed","PeriodicalId":233674,"journal":{"name":"Nigerian Journal of Life Sciences (ISSN: 2276-7029)","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124916798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

BACTERIAL FLORA OF CATFISH (Clarias gariepinus) FROM FISH PONDS IN LAGOS STATE, NIGERIA 尼日利亚拉各斯州鱼塘鲶鱼细菌区系研究

Nigerian Journal of Life Sciences (ISSN: 2276-7029) Pub Date : 2022-12-11 DOI: 10.52417/njls.v6i2.327

R. E. Uzeh, C. U. Onwuekweikpe

{"title":"BACTERIAL FLORA OF CATFISH (Clarias gariepinus) FROM FISH PONDS IN LAGOS STATE, NIGERIA","authors":"R. E. Uzeh, C. U. Onwuekweikpe","doi":"10.52417/njls.v6i2.327","DOIUrl":"https://doi.org/10.52417/njls.v6i2.327","url":null,"abstract":"Fish is a very important component of human diet. A total of 64 samples of Clarias gariepinus were collected from two fish ponds each in Yaba, Ijegun, Ikorodu and Epe in Lagos State, Nigeria. The bacterial flora of the fishes were determined quantitatively and qualitatively. The mean total viable count ranged from log10 7.6 cfu/g to log10 7.9 cfu/g. The bacterial load on the skin and in the intestine were generally higher than in the gills. Salmonella count ranged between log10 7.2 cfu/g and log10 7.6 cfu/g and it was highest in the intestine, followed by skin and gills. Coliform count was higher in the intestine and on the skin than the gills with range values of log10 7.6 cfu/g) to log10 7.9 cfu/g. Staphylococcal count was highest on the skin than the intestine and gills. The range of count was log10 7.2 cfu/g in the gills to log10 7.6 cfu/g on the skin. The bacteria isolated were identified based on cultural, morphological and biochemical characterization using Analytical Profile Index and they include Pseudomonas aeruginosa, Klebsiella pneumoniae, Salmonella typhi, Citrobacter amalonaticus, Vibrio fluvialis, Serratia odorifera, Acinetobacter baumannii, Proteus penneri, Burkholderia cepacia, Enterobacter pyrinus, Salmonella enteritidis, Edwardsiella tarda, Escherichia coli, Pseudomonas putida, Bacillus megaterium, Staphylococcus aureus, Bacillus mycoides, Corynebacterium pilosum, Bacillus subtilis, Micrococcus roseus, Bacillus cereus, Bacillus polymyxa, Micrococcus leteus and Corynebacterium kutscheri. The occurrence of pathogenic bacteria may constitute public health hazard","PeriodicalId":233674,"journal":{"name":"Nigerian Journal of Life Sciences (ISSN: 2276-7029)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114792336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COMPARATIVE ANTIMICROBIAL ACTIVITY OF SEVEN DISINFECTANTS MARKETTED IN LAGOS AGAINST CLINICAL BACTERIA ISOLATES 拉各斯市七种消毒剂对临床分离细菌的抑菌活性比较

Nigerian Journal of Life Sciences (ISSN: 2276-7029) Pub Date : 2022-12-11 DOI: 10.52417/njls.v6i2.340

C. Ayolabi, O. M. Adebayo, B. Adeniyi

{"title":"COMPARATIVE ANTIMICROBIAL ACTIVITY OF SEVEN DISINFECTANTS MARKETTED IN LAGOS AGAINST CLINICAL BACTERIA ISOLATES","authors":"C. Ayolabi, O. M. Adebayo, B. Adeniyi","doi":"10.52417/njls.v6i2.340","DOIUrl":"https://doi.org/10.52417/njls.v6i2.340","url":null,"abstract":"Antimicrobial effects of seven disinfectants were studied against a wide range of clinical bacterial isolates using Agar dilution method to determine the minimum inhibitory concentration (MIC). The active compounds of the disinfectants according to their manufacturer were D1-(Chloroxylenol 4.8% w/v), D2-(Chlorhexidinegluconate 0.3g and Centrimide 3.0% w/v), D3- (Centrimide 3.0% w/v and Chlorhexidinegluconate 0.3g), D4- (Dichloroxylenol 2% w/v), D5- (Sodium hypochlorite 3.85% m/v) and D6- (Halogenated phenol 0.68% and Sodium salicylate 0.052%). The test organisms were clinical isolates of Escherichia coli, Staphylococcus aureus and Salmonella enterica serotype Typhi. The MICs of the disinfectants ranges from 0.003%v/v to 2.5%v/v. This study showed that some of the disinfectants tested have strong bactericidal effect against the clinical bacteria isolates while others were less effective. Results also revealed that D2 which is made of Chlorhexidinegluconate 0.3g and centrimide 3.0% w/v has the greatest antibacterial activity. Likewise, antibacterial effects of the disinfectants are not only dependent on the types of disinfectant but also on their concentrations","PeriodicalId":233674,"journal":{"name":"Nigerian Journal of Life Sciences (ISSN: 2276-7029)","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133126732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HAEMATOLOGY AND PROXIMATE COMPOSITION OF NILE TILAPIA OREOCHROMIS NILOTICUS REARED ON THE FARM AND FROM THE WILD 养殖和野生尼罗罗非鱼的血液学和近似成分

Nigerian Journal of Life Sciences (ISSN: 2276-7029) Pub Date : 2022-12-11 DOI: 10.52417/njls.v6i2.333

A. Yusuff, O. Soyinka

引用次数: 0

THE EFFECT OF ANTI HYPERTENSIVE DRUGS ON TEAR SECRETION AND STABILITY 降压药对泪液分泌及稳定性的影响

Nigerian Journal of Life Sciences (ISSN: 2276-7029) Pub Date : 2022-12-11 DOI: 10.52417/njls.v6i2.334

A. O. Shuaibu, P. N. Uwabgoe, C. E. Odunze

{"title":"THE EFFECT OF ANTI HYPERTENSIVE DRUGS ON TEAR SECRETION AND STABILITY","authors":"A. O. Shuaibu, P. N. Uwabgoe, C. E. Odunze","doi":"10.52417/njls.v6i2.334","DOIUrl":"https://doi.org/10.52417/njls.v6i2.334","url":null,"abstract":"Hypertension is a chronic medical condition in which blood pressure in the arteries is elevated. This research work studied the effect of antihypertensive drugs specifically beta adrenergic blockers (atenolol) and angiotensin converting enzymes (lisinopril) on tears secretion and stability in adults. A total of 75 people (35 65years) male and female participated and completed the study with a mean age of 52.8±1.83years. These subjects were divided into group A (control) comprised of 25 normotensive subjects; group B (experimental) which comprised of 25 hypertensive subjects on atenolol alone (beta blocker) and group C (experimental) comprised of 25 hypertensive subjects on lisinopril (angiotensin converting enzymes ) alone .Tear volume was determined using schirmer strips and tear stability was determined using fluroscein strip. These patients were examined for all the tests at first week (baseline) and repetition of all tests one week later after oral drug administration of atenolol (Group B) or lisinopril (Group C). When the tear break up at time baseline and follow up measurement of group B were compared, it was observed that there was a statistically significant decrease (P<0.05). When the tear breakup time at baseline and follow up measurements of Group C were compared, it was observed that there was a statistically significant decreased.(P<0.05) The use of antihypertensive drugs atenolol (beta blocker) has an effect on the tear break up time. Also lisinopril (angiotensin converting enzyme inhibitor) has an effect on tear break time.","PeriodicalId":233674,"journal":{"name":"Nigerian Journal of Life Sciences (ISSN: 2276-7029)","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132195943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PUBLIC HEALTH IMPLICATION OF PAH AND TRACE HEAVY METALS IN SOIL SAMPLES FROM A PETEROLEUM REFINING AREA 石油炼制区土壤样品中多环芳烃和微量重金属对公众健康的影响

Nigerian Journal of Life Sciences (ISSN: 2276-7029) Pub Date : 2022-12-11 DOI: 10.52417/njls.v6i2.337

O. Ogbeide, A. Enuneku, R. Omorogbe, N. Chinye Ikejiunor, D. Dom-Etetafia, L. Ezemonye

{"title":"PUBLIC HEALTH IMPLICATION OF PAH AND TRACE HEAVY METALS IN SOIL SAMPLES FROM A PETEROLEUM REFINING AREA","authors":"O. Ogbeide, A. Enuneku, R. Omorogbe, N. Chinye Ikejiunor, D. Dom-Etetafia, L. Ezemonye","doi":"10.52417/njls.v6i2.337","DOIUrl":"https://doi.org/10.52417/njls.v6i2.337","url":null,"abstract":"The concentration of polyaromatic hydrocarbon and heavy metals in soil samples from vicinity around a petroleum refinery in Nigeria was investigated in an attempt to elucidate its public health implication. Soil samples were collected from three stations around the refinery; Ifie, Ijala and Ubeji which are in close proximity to the Refinery. Soil samples collected were digested and extracted for PAHs and Heavy metals using standard methods while analysis was carried out using a Gas Chromatograph and an Atomic Absorption Spectrophotometer respectively. Health impact of the concentrations of PAH and heavy metals were estimated using the chronic daily intake and the hazard quotient. Results showed varying concentrations of PAH and Heavy metals in soil samples from the vicinities close to Warri refinery. The concentrations of the heavy metals followed the sequence; Zn>Cu>Mn>Pb>Cr>Ni>Cd, while the predominant PAHs were Benzo (a) anthracene, pyrene and chrysene. Ubeji station had the highest PAH and heavy metal concentrations in soil samples. Health risk assessment of heavy metals showed that there were no potential noncarcinogenic effects from exposure through accidental ingestion, dermal contact and inhalation because estimates were below the safety threshold. However, health risks assessment of PAH in soil samples indicated that there is a potential for carcinogenic effects upon dermal exposure to PAH. This study highlights the environmental pollution problems and public health concerns of petroleum refining, particularly the potential hazards of to the health of individuals residing in areas close to the refinery.","PeriodicalId":233674,"journal":{"name":"Nigerian Journal of Life Sciences (ISSN: 2276-7029)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133427768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0