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Retraction to: MicroRNA-133a suppresses the proliferation, migration, and invasion of laryngeal carcinoma cells by targeting CD47. MicroRNA-133a通过靶向CD47抑制喉癌细胞的增殖、迁移和侵袭。
Tumor Biology Pub Date : 2022-01-01 DOI: 10.3233/TUB-229002
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引用次数: 0
Retraction to: Long non-coding RNA TUSC7 acts a molecular sponge for miR-10a and suppresses EMT in hepatocellular carcinoma. 缩回:长链非编码RNA TUSC7作为miR-10a的分子海绵，抑制肝细胞癌中的EMT。
Tumor Biology Pub Date : 2022-01-01 DOI: 10.3233/TUB-229001
{"title":"Retraction to: Long non-coding RNA TUSC7 acts a molecular sponge for miR-10a and suppresses EMT in hepatocellular carcinoma.","authors":"","doi":"10.3233/TUB-229001","DOIUrl":"https://doi.org/10.3233/TUB-229001","url":null,"abstract":"","PeriodicalId":23364,"journal":{"name":"Tumor Biology","volume":"44 1","pages":"231"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10737437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exosomes in the visual system: New avenues in ocular diseases. 视觉系统中的外泌体:眼部疾病的新途径。
Tumor Biology Pub Date : 2022-01-01 DOI: 10.3233/TUB-211543
Radhika Manukonda, Jyothi Attem, Vengala Rao Yenuganti, Swathi Kaliki, Geeta K Vemuganti
{"title":"Exosomes in the visual system: New avenues in ocular diseases.","authors":"Radhika Manukonda,&nbsp;Jyothi Attem,&nbsp;Vengala Rao Yenuganti,&nbsp;Swathi Kaliki,&nbsp;Geeta K Vemuganti","doi":"10.3233/TUB-211543","DOIUrl":"https://doi.org/10.3233/TUB-211543","url":null,"abstract":"<p><p>Exosomes are a subgroup of membrane-bound extracellular vesicles secreted by all cell types and present virtually in all biological fluids. The composition of exosomes in the same cell type varies in healthy and disease conditions. Hence, exosomes research is a prime focus area for clinical research in cancer and numerous age-related metabolic syndromes. Functions of exosomes include crucial cell-to-cell communication that mediates complex cellular processes, such as antigen presentation, stem cell differentiation, and angiogenesis. However, very few studies reported the presence and role of exosomes in normal physiological and pathological conditions of specialized ocular tissues of the eye and ocular cancers. The eye being a protected sense organ with unique connectivity with the rest of the body through the blood and natural passages, we believe that the role of exosomes in ocular tissues will significantly improve our understanding of ocular diseases and their interactions with the rest of the body. We present a review that highlights the existence and function of exosomes in various ocular tissues, their role in the progression of some of the neoplastic and non-neoplastic conditions of the eyes.</p>","PeriodicalId":23364,"journal":{"name":"Tumor Biology","volume":" ","pages":"129-152"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40611222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Erratum to: SMAD4 and its role in pancreatic cancer. SMAD4及其在胰腺癌中的作用。
Tumor Biology Pub Date : 2022-01-01 DOI: 10.3233/TUB-229004
{"title":"Erratum to: SMAD4 and its role in pancreatic cancer.","authors":"","doi":"10.3233/TUB-229004","DOIUrl":"https://doi.org/10.3233/TUB-229004","url":null,"abstract":"","PeriodicalId":23364,"journal":{"name":"Tumor Biology","volume":"44 1","pages":"237"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10369580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unfavorable prognosis and clinical consequences of APOBEC3B expression in breast and other cancers: A systematic review and meta-analysis. APOBEC3B在乳腺癌和其他癌症中的不良预后和临床后果:一项系统综述和荟萃分析。
Tumor Biology Pub Date : 2022-01-01 DOI: 10.3233/TUB-211577
Sima Jafarpour, Maryam Yazdi, Reza Nedaeinia, Sepideh Ghobakhloo, Rasoul Salehi
{"title":"Unfavorable prognosis and clinical consequences of APOBEC3B expression in breast and other cancers: A systematic review and meta-analysis.","authors":"Sima Jafarpour,&nbsp;Maryam Yazdi,&nbsp;Reza Nedaeinia,&nbsp;Sepideh Ghobakhloo,&nbsp;Rasoul Salehi","doi":"10.3233/TUB-211577","DOIUrl":"https://doi.org/10.3233/TUB-211577","url":null,"abstract":"<p><strong>Introduction: </strong>Controversy exists regarding the association of apolipoprotein B mRNA editing enzyme catalytic subunit 3B APOBEC3B, (A3B) overexpression and poor prognosis, metastasis, and chemotherapy drug resistance in cancers. Here we conducted a systematic review and meta-analysis to determine its prognostic value and clinicopathological features in breast cancer and some other malignancies.</p><p><strong>Materials and methods: </strong>PubMed, Scopus, Cochrane Library, Web of Science, and EMBASE were searched up to Feb 2022 for the association of A3B with breast, ovarian, gastrointestinal and lung cancers. The pooled hazard ratios with 95% confidence interval (CI) were evaluated to assess disease-free survival (DFS), overall survival (OS), and recurrence-free survival (RFS) in cancers under study.</p><p><strong>Results: </strong>Over 3700 patients were included in this meta-survey. Elevated levels of A3B were significantly related to low OS (pooled HR = 1.30; 95% CI:1.09-1.55, P < 0.01), poor DFS (pooled HR = 1.66; 95% CI:1.17-2.35, P < 0.01) and poor RFS (HR = 1.51, 95% CI:1.11-2.04, P = 0.01). Subgroup analysis revealed that high A3B expression was associated with poor OS in lung (HR = 1.85, 95% CI: 1.40-2.45), and breast cancers (HR = 1.38, 95% CI: 1.00-1.89). High expression of A3B did not display any significant association with clinicopathologic features.</p><p><strong>Conclusion: </strong>APOBEC3B overexpression is related to poor OS, DFS and RFS only in some cancer types and no generalized role could be predicted for all cancers.</p>","PeriodicalId":23364,"journal":{"name":"Tumor Biology","volume":" ","pages":"153-169"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33462097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Erratum to: Galectin-3: A factotum in carcinogenesis bestowing an archery for prevention 勘误表：半乳糖凝集素-3：致癌作用中的一位杂役授予预防箭术
Tumor Biology Pub Date : 2021-11-09 DOI: 10.3233/tub-219009
T. Ram
{"title":"Erratum to: Galectin-3: A factotum in carcinogenesis bestowing an archery for prevention","authors":"T. Ram","doi":"10.3233/tub-219009","DOIUrl":"https://doi.org/10.3233/tub-219009","url":null,"abstract":"","PeriodicalId":23364,"journal":{"name":"Tumor Biology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49217127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Abstract 2992: Proteogenomic characterization of triple-negative breast cancer patient-derived xenografts reveals molecular correlates of differential chemotherapy response and potential therapeutic targets to overcome resistance 摘要2992:三阴性乳腺癌患者来源的异种移植物的蛋白质基因组学特征揭示了差异化疗反应的分子相关性和克服耐药性的潜在治疗靶点
Tumor Biology Pub Date : 2021-07-01 DOI: 10.1158/1538-7445.AM2021-2992
Jonathan T. Lei, Chen Huang, R. R. Srinivasan, S. Vasaikar, L. Dobrolecki, Alaina N. Lewis, Christina Sallas, S. Hilsenbeck, C. Osborne, M. Rimawi, M. Ellis, V. Petrosyan, Alexander B. Saltzman, A. Malovannaya, G. Wulf, D. Kraushaar, Tao Wang, G. Echeverria, Bing Zhang, M. Lewis
{"title":"Abstract 2992: Proteogenomic characterization of triple-negative breast cancer patient-derived xenografts reveals molecular correlates of differential chemotherapy response and potential therapeutic targets to overcome resistance","authors":"Jonathan T. Lei, Chen Huang, R. R. Srinivasan, S. Vasaikar, L. Dobrolecki, Alaina N. Lewis, Christina Sallas, S. Hilsenbeck, C. Osborne, M. Rimawi, M. Ellis, V. Petrosyan, Alexander B. Saltzman, A. Malovannaya, G. Wulf, D. Kraushaar, Tao Wang, G. Echeverria, Bing Zhang, M. Lewis","doi":"10.1158/1538-7445.AM2021-2992","DOIUrl":"https://doi.org/10.1158/1538-7445.AM2021-2992","url":null,"abstract":"","PeriodicalId":23364,"journal":{"name":"Tumor Biology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44882064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract 3145: TRIPODD: a novel fluorescence imaging platform for in situ quantification of drug distribution and therapeutic response TRIPODD:一种用于原位定量药物分布和治疗反应的新型荧光成像平台
Tumor Biology Pub Date : 2021-07-01 DOI: 10.1158/1538-7445.AM2021-3145
Nathan P. McMahon, Allison Solanki, Jocelyn A. Jones, Lei G. Wang, K. Tichauer, K. Samkoe, Summer L. Gibbs
{"title":"Abstract 3145: TRIPODD: a novel fluorescence imaging platform for in situ quantification of drug distribution and therapeutic response","authors":"Nathan P. McMahon, Allison Solanki, Jocelyn A. Jones, Lei G. Wang, K. Tichauer, K. Samkoe, Summer L. Gibbs","doi":"10.1158/1538-7445.AM2021-3145","DOIUrl":"https://doi.org/10.1158/1538-7445.AM2021-3145","url":null,"abstract":"","PeriodicalId":23364,"journal":{"name":"Tumor Biology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44898617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract 2755: Single-cell RNA sequencing reveals priming professional antigen-presenting macrophages and chemokine expressing T cells in tumor microenvironment by AXL inhibitor, SKI-G-801 摘要2755:单细胞RNA测序揭示了AXL抑制剂SKI-G-801在肿瘤微环境中启动专业抗原呈递巨噬细胞和表达趋化因子的T细胞
Tumor Biology Pub Date : 2021-07-01 DOI: 10.1158/1538-7445.AM2021-2755
Kyung-Ho Pyo, H. K. Lee, H. Jo, Wongeun Lee, S. Heo, S. Lim, Dong Kwon Kim, Chun-Bong Synn, Y. Byeon, Young Seob Kim, B. Ahn, M. Hong, S. Lim, H. Kim, B. Cho
{"title":"Abstract 2755: Single-cell RNA sequencing reveals priming professional antigen-presenting macrophages and chemokine expressing T cells in tumor microenvironment by AXL inhibitor, SKI-G-801","authors":"Kyung-Ho Pyo, H. K. Lee, H. Jo, Wongeun Lee, S. Heo, S. Lim, Dong Kwon Kim, Chun-Bong Synn, Y. Byeon, Young Seob Kim, B. Ahn, M. Hong, S. Lim, H. Kim, B. Cho","doi":"10.1158/1538-7445.AM2021-2755","DOIUrl":"https://doi.org/10.1158/1538-7445.AM2021-2755","url":null,"abstract":"","PeriodicalId":23364,"journal":{"name":"Tumor Biology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44961716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract 2995: Zebrafish tumor-derived xenografts established from breast cancer pdx models predict treatment outcome and dissemination risk with superior sensitivity and specificity 摘要2995：从癌症pdx模型建立的斑马鱼肿瘤衍生异种移植物以优异的敏感性和特异性预测治疗结果和扩散风险
Tumor Biology Pub Date : 2021-07-01 DOI: 10.1158/1538-7445.AM2021-2995
Gabriela Vazquez Rodriguez, Z. Ali, Anna Erkstam, J. Schueler, A. Fahlgren, Lasse D. Jensen
{"title":"Abstract 2995: Zebrafish tumor-derived xenografts established from breast cancer pdx models predict treatment outcome and dissemination risk with superior sensitivity and specificity","authors":"Gabriela Vazquez Rodriguez, Z. Ali, Anna Erkstam, J. Schueler, A. Fahlgren, Lasse D. Jensen","doi":"10.1158/1538-7445.AM2021-2995","DOIUrl":"https://doi.org/10.1158/1538-7445.AM2021-2995","url":null,"abstract":"","PeriodicalId":23364,"journal":{"name":"Tumor Biology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45028725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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