Victor Sadauskas, Mariame Fofana, Dalton Brunson, Jeff Choi, David Spain, James V Quinn, Youyou Duanmu
{"title":"Serratus anterior plane block improves pain and incentive spirometry volumes in trauma patients with multiple rib fractures: a prospective cohort study.","authors":"Victor Sadauskas, Mariame Fofana, Dalton Brunson, Jeff Choi, David Spain, James V Quinn, Youyou Duanmu","doi":"10.1136/tsaco-2023-001183","DOIUrl":"10.1136/tsaco-2023-001183","url":null,"abstract":"<p><strong>Background: </strong>Rib fractures are common injuries associated with considerable morbidity, long-term disability, and mortality. Early, adequate analgesia is important to mitigate complications such as pneumonia and respiratory failure. Regional anesthesia has been proposed for rib fracture pain control due to its superior side effect profile compared with systemic analgesia. Our objective was to evaluate the effect of emergency physician-performed, ultrasound-guided serratus anterior plane block (SAPB) on pain and respiratory function in emergency department patients with multiple acute rib fractures.</p><p><strong>Methods: </strong>This was a prospective observational cohort study of adult patients at a level 1 trauma center who had two or more acute unilateral rib fractures. Eligible patients received a SAPB if an emergency physician trained in the procedure was available at the time of diagnosis. Primary outcomes were the absolute change in pain scores and percent change in expected incentive spirometry volumes from baseline to 3 hours after rib fracture diagnosis.</p><p><strong>Results: </strong>38 patients met eligibility criteria, 15 received the SAPB and 23 did not. The SAPB group had a greater decrease in pain scores at 3 hours (-3.7 vs. -0.9; p=0.003) compared with the non-SAPB group. The SAPB group also had an 11% (CI 1.5% to 17%) increase in percent expected spirometry volumes at 3 hours which was significantly better than the non-SAPB group, which had a -3% (CI -9.1% to 2.7%) decrease (p=0.008).</p><p><strong>Conclusion: </strong>Patients with rib fractures who received SAPB as part of a multimodal pain control strategy had a greater improvement in pain and respiratory function compared with those who did not. Larger trials are indicated to assess the generalizability of these initial findings.</p>","PeriodicalId":23307,"journal":{"name":"Trauma Surgery & Acute Care Open","volume":"9 1","pages":"e001183"},"PeriodicalIF":2.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11177771/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141331853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kaushik Mukherjee, George Kasotakis, Suresh Agarwal
{"title":"It takes a village and a multimodal toolbox: pain control after multiple rib fractures.","authors":"Kaushik Mukherjee, George Kasotakis, Suresh Agarwal","doi":"10.1136/tsaco-2024-001478","DOIUrl":"10.1136/tsaco-2024-001478","url":null,"abstract":"","PeriodicalId":23307,"journal":{"name":"Trauma Surgery & Acute Care Open","volume":"9 1","pages":"e001478"},"PeriodicalIF":2.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11177768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141331851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jacklyn Luu, Evgenia Borisenko, Valerie Przekop, Advait Patil, Joseph D Forrester, Jeff Choi
{"title":"Practical guide to building machine learning-based clinical prediction models using imbalanced datasets.","authors":"Jacklyn Luu, Evgenia Borisenko, Valerie Przekop, Advait Patil, Joseph D Forrester, Jeff Choi","doi":"10.1136/tsaco-2023-001222","DOIUrl":"10.1136/tsaco-2023-001222","url":null,"abstract":"<p><p>Clinical prediction models often aim to predict rare, high-risk events, but building such models requires robust understanding of imbalance datasets and their unique study design considerations. This practical guide highlights foundational prediction model principles for surgeon-data scientists and readers who encounter clinical prediction models, from feature engineering and algorithm selection strategies to model evaluation and design techniques specific to imbalanced datasets. We walk through a clinical example using readable code to highlight important considerations and common pitfalls in developing machine learning-based prediction models. We hope this practical guide facilitates developing and critically appraising robust clinical prediction models for the surgical community.</p>","PeriodicalId":23307,"journal":{"name":"Trauma Surgery & Acute Care Open","volume":"9 1","pages":"e001222"},"PeriodicalIF":2.1,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11177772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141331852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jenna Kroeker, Anas Wess, Yuwei Yang, Bader Al-Zeer, Harjot Uppal, Patricia Balmes, Robin Som, Valerie Courval, Nasira Lakha, Angie Brisson, Jennifer Sakai, Naisan Garraway, Raymond Tang, Peter Rose, Emilie Joos
{"title":"Chest trauma clinical practice guideline protects against delirium in patients with rib fractures.","authors":"Jenna Kroeker, Anas Wess, Yuwei Yang, Bader Al-Zeer, Harjot Uppal, Patricia Balmes, Robin Som, Valerie Courval, Nasira Lakha, Angie Brisson, Jennifer Sakai, Naisan Garraway, Raymond Tang, Peter Rose, Emilie Joos","doi":"10.1136/tsaco-2023-001323","DOIUrl":"10.1136/tsaco-2023-001323","url":null,"abstract":"<p><strong>Introduction: </strong>Traumatic rib fractures present a considerable risk to patient well-being, contributing to morbidity and mortality in trauma patients. To address the risks associated with rib fractures, evidence-based interventions have been implemented, including effective pain management, pulmonary hygiene, and early walking. Vancouver General Hospital, a level 1 trauma center in British Columbia, Canada, developed a comprehensive multidisciplinary chest trauma clinical practice guideline (CTCPG) to optimize the management of patients with rib fractures. This prospective cohort study aimed to assess the impact of the CTCPG on pain management interventions and patient outcomes.</p><p><strong>Methods: </strong>The study involved patients admitted between January 1, 2021 and December 31, 2021 (post-CTCPG cohort) and a historical control group admitted between November 1, 2018 and December 31, 2019 (pre-CTCPG cohort). Patient data were collected from patient charts and the British Columbia Trauma Registry, including demographics, injury characteristics, pain management interventions, and relevant outcomes.</p><p><strong>Results: </strong>Implementation of the CTCPG resulted in an increased use of multimodal pain therapy (99.4% vs 96.1%; p=0.03) and a significant reduction in the incidence of delirium in the post-CTCPG cohort (OR 0.43, 95% CI 0.21 to 0.80, p=0.0099). There were no significant differences in hospital length of stay, ICU (intensive care unit) days, non-invasive positive pressure ventilation requirement, ventilator days, pneumonia incidence, or mortality between the two cohorts.</p><p><strong>Discussion: </strong>Adoption of a CTCPG improved chest trauma management by enhancing pain management and reducing the incidence of delirium. Further research, including multicenter studies, is warranted to validate these findings and explore additional potential benefits of the CTCPG in the management of chest trauma patients.</p><p><strong>Level of evidence: </strong>IIb.</p>","PeriodicalId":23307,"journal":{"name":"Trauma Surgery & Acute Care Open","volume":"9 1","pages":"e001323"},"PeriodicalIF":2.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11163824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141301712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Narayan Yoganandan, Alok Shah, Jamie Baisden, Brian Stemper, Mary Otterson, Lewis Somberg, Cameron Bass, Robert Salzar, Justin McMahon, Carol Chancey, Joseph McEntire
{"title":"Matched-pair hybrid test paradigm for behind armor blunt trauma using an experimental animal model.","authors":"Narayan Yoganandan, Alok Shah, Jamie Baisden, Brian Stemper, Mary Otterson, Lewis Somberg, Cameron Bass, Robert Salzar, Justin McMahon, Carol Chancey, Joseph McEntire","doi":"10.1136/tsaco-2023-001194","DOIUrl":"10.1136/tsaco-2023-001194","url":null,"abstract":"<p><strong>Background: </strong>The current behind armor blunt trauma (BABT) injury criterion uses a single penetration limit of 44 mm in Roma Plastilina clay and is not specific to thoracoabdominal regions. However, different regions in the human body have different injury tolerances. This manuscript presents a matched-pair hybrid test paradigm with different experimental models and candidate metrics to develop regional human injury criteria.</p><p><strong>Methods: </strong>Live and cadaver swine were used as matched pair experimental models. An impactor simulating backface deformation profiles produced by body armor from military-relevant ballistics was used to deliver BABT loading to liver and lung regions in cadaver and live swine. Impact loading was characterized using peak accelerations and energy. For live swine, physiological parameters were monitored for 6 hours, animals were euthanized, and a detailed necropsy was done to identify injuries to skeletal structures, organs and soft tissues. A similar process was used to identify injuries to the cadaver swine for targeted thoracoabdominal regions.</p><p><strong>Results: </strong>Two cadavers and one live swine were subjected to BABT impacts to the liver. One cadaver and one live swine were subjected to BABT impacts to the left lung. Injuries to both regions were similar at similar energies between the cadaver and live models.</p><p><strong>Conclusions: </strong>Swine is an established animal for thoracoabdominal impact studies in automotive standards, although at lower insult levels. Similarities in BABT responses between cadaver and live swine allow for extending testing protocols to human cadavers and for the development of scaling relationships between animal and human cadavers, acting as a hybrid protocol between species and live and cadaver models. Injury tolerances and injury risk curves from live animals can be converted to human tolerances via structural scaling using these outcomes. The present experimental paradigm can be used to develop region-based BABT injury criteria, which are not currently available.</p>","PeriodicalId":23307,"journal":{"name":"Trauma Surgery & Acute Care Open","volume":"9 1","pages":"e001194"},"PeriodicalIF":2.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11163657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141301713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bethany Lauren Strong, Latoya Silverton, William Wical, Sharon M Henry
{"title":"Reaching back to enhance the future: the American Association for the Surgery of Trauma Diversity, Equity and Inclusion Pipeline Program.","authors":"Bethany Lauren Strong, Latoya Silverton, William Wical, Sharon M Henry","doi":"10.1136/tsaco-2023-001339","DOIUrl":"10.1136/tsaco-2023-001339","url":null,"abstract":"<p><strong>Objectives: </strong>There are significant disparities in the surgical workforce in comparison with medical student demographics. Pipeline programs have shown to be effective in addressing gaps. The American Association for the Surgery of Trauma Diversity, Equity and Inclusion Committee designed a longitudinal pipeline program with high school student mentees and surgeon mentors providing an in-person hands-on workshop.</p><p><strong>Methods: </strong>The mentee demographics and socioeconomic status at the time of application were determined using overall percentages and the Area Deprivation Index (ADI). Program application essays were qualitatively analyzed for common themes. The pre-workshop and post-workshop and 6-month follow-up surveys were analyzed for mentee experience and areas for improvement.</p><p><strong>Results: </strong>Mentees selected were 30% male (N=3 of 10), 70% female (N=7 of 10), 50% black or African American (N=5 of 10) and 30% Hispanic or Latinx (N=3 of 10). The majority of mentees were in the most disadvantaged groups in their state by the ADI (N=8 of 9, 89%). Many of the application essays highlighted a personal loss as driving the interest in a health career with several of those losses based on 'gun violence'. There was under-representation in medicine racial/ethnic or gender concordance for 80% (N=8 of 10) of the mentee-mentor pairings. In the pre-workshop survey, even those students with high-grade point averages and strong academic achievement in science courses indicated low confidence in their ability to succeed. Most students (N=7 of 10, 70%) reported a strong positive connection with their mentor in the post-workshop survey. There was a reduction in self-identified modifiable barriers to success for 83% (N=5 of 6) of the mentees. One-third of students who responded to the 6-month survey indicated that they had issues with maintaining contact with their mentors after the workshop.</p><p><strong>Conclusion: </strong>The pipeline program was able to reach the target demographic and increase interest in surgery. Positive mentee/mentor relationships were formed. There are improvements to be made in longitudinal components of the program to ensure lasting results.</p><p><strong>Level of evidence: </strong>III.</p>","PeriodicalId":23307,"journal":{"name":"Trauma Surgery & Acute Care Open","volume":"9 1","pages":"e001339"},"PeriodicalIF":2.1,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11149148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Value of trauma registries in improving global trauma outcomes.","authors":"Mark T Yost, Serge Ngekeng, Catherine Juillard","doi":"10.1136/tsaco-2024-001507","DOIUrl":"10.1136/tsaco-2024-001507","url":null,"abstract":"","PeriodicalId":23307,"journal":{"name":"Trauma Surgery & Acute Care Open","volume":"9 1","pages":"e001507"},"PeriodicalIF":2.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11149168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rachel D Appelbaum, Michael S Farrell, Rondi B Gelbard, J Jason Hoth, Randeep S Jawa, Jordan M Kirsch, Samuel Mandell, Eden A Nohra, Tanya Rinderknecht, Susan Rowell, Joseph Cuschieri, Deborah M Stein
{"title":"Antibiotic prophylaxis in injury: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document.","authors":"Rachel D Appelbaum, Michael S Farrell, Rondi B Gelbard, J Jason Hoth, Randeep S Jawa, Jordan M Kirsch, Samuel Mandell, Eden A Nohra, Tanya Rinderknecht, Susan Rowell, Joseph Cuschieri, Deborah M Stein","doi":"10.1136/tsaco-2023-001304","DOIUrl":"10.1136/tsaco-2023-001304","url":null,"abstract":"","PeriodicalId":23307,"journal":{"name":"Trauma Surgery & Acute Care Open","volume":"9 1","pages":"e001304"},"PeriodicalIF":2.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11149135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141249321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Steven Farrell, John Varujan Agapian, Rachel D Appelbaum, Dina M Filiberto, Rondi Gelbard, Jason Hoth, Randeep Jawa, Jordan Kirsch, Matthew E Kutcher, Eden Nohra, Abhijit Pathak, Jasmeet Paul, Bryce Robinson, Joseph Cuschieri, Deborah M Stein
{"title":"Surgical and procedural antibiotic prophylaxis in the surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document.","authors":"Michael Steven Farrell, John Varujan Agapian, Rachel D Appelbaum, Dina M Filiberto, Rondi Gelbard, Jason Hoth, Randeep Jawa, Jordan Kirsch, Matthew E Kutcher, Eden Nohra, Abhijit Pathak, Jasmeet Paul, Bryce Robinson, Joseph Cuschieri, Deborah M Stein","doi":"10.1136/tsaco-2023-001305","DOIUrl":"10.1136/tsaco-2023-001305","url":null,"abstract":"<p><p>The use of prophylactic measures, including perioperative antibiotics, for the prevention of surgical site infections is a standard of care across surgical specialties. Unfortunately, the routine guidelines used for routine procedures do not always account for many of the factors encountered with urgent/emergent operations and critically ill or high-risk patients. This clinical consensus document created by the American Association for the Surgery of Trauma Critical Care Committee is one of a three-part series and reviews surgical and procedural antibiotic prophylaxis in the surgical intensive care unit. The purpose of this clinical consensus document is to provide practical recommendations, based on expert opinion, to assist intensive care providers with decision-making for surgical prophylaxis. We specifically evaluate the current state of periprocedural antibiotic management of external ventricular drains, orthopedic operations (closed and open fractures, silver dressings, local, antimicrobial adjuncts, spine surgery, subfascial drains), abdominal operations (bowel injury and open abdomen), and bedside procedures (thoracostomy tube, gastrostomy tube, tracheostomy).</p>","PeriodicalId":23307,"journal":{"name":"Trauma Surgery & Acute Care Open","volume":"9 1","pages":"e001305"},"PeriodicalIF":2.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11149119/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eden Nohra, Rachel D Appelbaum, Michael Steven Farrell, Thomas Carver, Hee Soo Jung, Jordan Michael Kirsch, Lisa M Kodadek, Samuel Mandell, Aussama Khalaf Nassar, Abhijit Pathak, Jasmeet Paul, Bryce Robinson, Joseph Cuschieri, Deborah M Stein
{"title":"Fever and infections in surgical intensive care: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document.","authors":"Eden Nohra, Rachel D Appelbaum, Michael Steven Farrell, Thomas Carver, Hee Soo Jung, Jordan Michael Kirsch, Lisa M Kodadek, Samuel Mandell, Aussama Khalaf Nassar, Abhijit Pathak, Jasmeet Paul, Bryce Robinson, Joseph Cuschieri, Deborah M Stein","doi":"10.1136/tsaco-2023-001303","DOIUrl":"10.1136/tsaco-2023-001303","url":null,"abstract":"<p><p>The evaluation and workup of fever and the use of antibiotics to treat infections is part of daily practice in the surgical intensive care unit (ICU). Fever can be infectious or non-infectious; it is important to distinguish between the two entities wherever possible. The evidence is growing for shortening the duration of antibiotic treatment of common infections. The purpose of this clinical consensus document, created by the American Association for the Surgery of Trauma Critical Care Committee, is to synthesize the available evidence, and to provide practical recommendations. We discuss the evaluation of fever, the indications to obtain cultures including urine, blood, and respiratory specimens for diagnosis of infections, the use of procalcitonin, and the decision to initiate empiric antibiotics. We then describe the treatment of common infections, specifically ventilator-associated pneumonia, catheter-associated urinary infection, catheter-related bloodstream infection, bacteremia, surgical site infection, intra-abdominal infection, ventriculitis, and necrotizing soft tissue infection.</p>","PeriodicalId":23307,"journal":{"name":"Trauma Surgery & Acute Care Open","volume":"9 1","pages":"e001303"},"PeriodicalIF":2.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11149120/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}