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Structural Analysis of the Key Intermediate Formed during Transcription through a Nucleosome. 核小体转录过程中关键中间体的结构分析。
Trends in cell & molecular biology Pub Date : 2013-01-01
H-W Chang, A K Shaytan, F-K Hsieh, O I Kulaeva, M P Kirpichnikov, V M Studitsky
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引用次数: 0
Decoding in Candidatus Riesia pediculicola, close to a minimal tRNA modification set? 在马梗候选酵母中解码，接近最小tRNA修饰集?
Trends in cell & molecular biology Pub Date : 2012-01-01
Valérie de Crécy-Lagard, Christian Marck, Henri Grosjean
{"title":"Decoding in Candidatus Riesia pediculicola, close to a minimal tRNA modification set?","authors":"Valérie de Crécy-Lagard,&nbsp;Christian Marck,&nbsp;Henri Grosjean","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A comparative genomic analysis of the recently sequenced human body louse unicellular endosymbiont Candidatus Riesia pediculicola with a reduced genome (582 Kb), revealed that it is the only known organism that might have lost all post-transcriptional base and ribose modifications of the tRNA body, retaining only modifications of the anticodon-stem-loop essential for mRNA decoding. Such a minimal tRNA modification set was not observed in other insect symbionts or in parasitic unicellular bacteria, such as Mycoplasma genitalium (580 Kb), that have also evolved by considerably reducing their genomes. This could be an example of a minimal tRNA modification set required for life, a question that has been at the center of the field for many years, especially for understanding the emergence and evolution of the genetic code.</p>","PeriodicalId":23241,"journal":{"name":"Trends in cell & molecular biology","volume":"7 ","pages":"11-34"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539174/pdf/nihms385606.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31154870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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