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Mechanisms of lung injury and repair最新文献

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High-resolution transcriptomic and epigenetic profiling across disease stages identifies novel regulators of COPD phenotypes. 跨疾病阶段的高分辨率转录组学和表观遗传学分析确定了COPD表型的新调节因子。
Mechanisms of lung injury and repair Pub Date : 2022-03-10 DOI: 10.1183/23120541.lsc-2022.202
M. Llamazares Prada, U. Schwartz, S. Pohl, M. Richter, Michael Schuller, Corinna Keller, V. Mijošek, T. Muley, M. Schneider, R. Tamas, Karsten Quast, Joschka Hey, C. Heussel, A. Warth, H. Winter, H. Karmouty-quintana, F. Herth, I. Koch, D. Weichenhan, T. Jurkowski, Charles D. Imbusch, B. Brors, V. Beneš, Brigit Jung, H. Stahl, David Wyatt, C. Plass, R. Jurkowska
{"title":"High-resolution transcriptomic and epigenetic profiling across disease stages identifies novel regulators of COPD phenotypes.","authors":"M. Llamazares Prada, U. Schwartz, S. Pohl, M. Richter, Michael Schuller, Corinna Keller, V. Mijošek, T. Muley, M. Schneider, R. Tamas, Karsten Quast, Joschka Hey, C. Heussel, A. Warth, H. Winter, H. Karmouty-quintana, F. Herth, I. Koch, D. Weichenhan, T. Jurkowski, Charles D. Imbusch, B. Brors, V. Beneš, Brigit Jung, H. Stahl, David Wyatt, C. Plass, R. Jurkowska","doi":"10.1183/23120541.lsc-2022.202","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.202","url":null,"abstract":"","PeriodicalId":232074,"journal":{"name":"Mechanisms of lung injury and repair","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115273766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cigarette smoke and air pollution induce dysfunctional pulmonary microvascular endothelial repair 吸烟和空气污染导致肺微血管内皮修复功能失调
Mechanisms of lung injury and repair Pub Date : 2022-03-10 DOI: 10.1183/23120541.lsc-2022.141
Xinhui Wu, S. Bos, A. Ravi, A. M. van der Does, A. D. van der Meer, P. Hiemstra, Jill Johnson, Martin Harmsen, R. Gosens
{"title":"Cigarette smoke and air pollution induce dysfunctional pulmonary microvascular endothelial repair","authors":"Xinhui Wu, S. Bos, A. Ravi, A. M. van der Does, A. D. van der Meer, P. Hiemstra, Jill Johnson, Martin Harmsen, R. Gosens","doi":"10.1183/23120541.lsc-2022.141","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.141","url":null,"abstract":"","PeriodicalId":232074,"journal":{"name":"Mechanisms of lung injury and repair","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129789136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monocyte migration and COPD pathogenesis are epigenetically regulated by PRMT7 单核细胞迁移和COPD发病机制受PRMT7的表观遗传调控
Mechanisms of lung injury and repair Pub Date : 2022-03-10 DOI: 10.1183/23120541.lsc-2022.178
A. Jeridi, T. Conlon, G. Günes Günsel, N. Lang, G. Burgstaller, H. V. Van Eeckhoutte, S. Verleden, T. Stöger, M. Königshoff, O. Eickelberg, K. Bracke, H. Watz, H. Schiller, R. Schneider, A. Yildirim
{"title":"Monocyte migration and COPD pathogenesis are epigenetically regulated by PRMT7","authors":"A. Jeridi, T. Conlon, G. Günes Günsel, N. Lang, G. Burgstaller, H. V. Van Eeckhoutte, S. Verleden, T. Stöger, M. Königshoff, O. Eickelberg, K. Bracke, H. Watz, H. Schiller, R. Schneider, A. Yildirim","doi":"10.1183/23120541.lsc-2022.178","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.178","url":null,"abstract":"","PeriodicalId":232074,"journal":{"name":"Mechanisms of lung injury and repair","volume":"147 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134490642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
G-protein coupled receptor 87 is a novel basal cell marker in distal IPF bronchioles g蛋白偶联受体87是远端IPF细支气管中一种新的基底细胞标志物
Mechanisms of lung injury and repair Pub Date : 2022-03-10 DOI: 10.1183/23120541.lsc-2022.62
M. Lehmann, K. Heinzelmann, Q. Hu, E. Dobrinskikh, H. Ulke, Colton Leavitt, Carol Mirita, T. Trudeau, M. Saal, P. Rice, M. Ansari, B. Gao, W. Janssen, Ivana Y Yang, H. Schiller, E. Vladar, M. Königshoff
{"title":"G-protein coupled receptor 87 is a novel basal cell marker in distal IPF bronchioles","authors":"M. Lehmann, K. Heinzelmann, Q. Hu, E. Dobrinskikh, H. Ulke, Colton Leavitt, Carol Mirita, T. Trudeau, M. Saal, P. Rice, M. Ansari, B. Gao, W. Janssen, Ivana Y Yang, H. Schiller, E. Vladar, M. Königshoff","doi":"10.1183/23120541.lsc-2022.62","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.62","url":null,"abstract":"","PeriodicalId":232074,"journal":{"name":"Mechanisms of lung injury and repair","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122659055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinically relevant levels of hyperoxia lead to cell cycle arrest and long-term changes in DNA repair in the developing lung 临床相关的高氧水平导致细胞周期阻滞和发育中的肺DNA修复的长期变化
Mechanisms of lung injury and repair Pub Date : 2022-03-10 DOI: 10.1183/23120541.lsc-2022.142
Erika González, Juan Henao, Markus Mueller, F. Schelter, T. Carell, B. Schubert, A. Hilgendorff
{"title":"Clinically relevant levels of hyperoxia lead to cell cycle arrest and long-term changes in DNA repair in the developing lung","authors":"Erika González, Juan Henao, Markus Mueller, F. Schelter, T. Carell, B. Schubert, A. Hilgendorff","doi":"10.1183/23120541.lsc-2022.142","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.142","url":null,"abstract":"","PeriodicalId":232074,"journal":{"name":"Mechanisms of lung injury and repair","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127511842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomarker identification to assess effects of bone-marrow derived mesenchymal stromal cell-therapy in emphysema through immune profiling 通过免疫谱分析评估骨髓间充质细胞治疗肺气肿的生物标志物鉴定
Mechanisms of lung injury and repair Pub Date : 2022-03-10 DOI: 10.1183/23120541.lsc-2022.195
P. Khedoe, Lijun Jia, Na Li, P. Hiemstra, F. Koning, J. Stolk
{"title":"Biomarker identification to assess effects of bone-marrow derived mesenchymal stromal cell-therapy in emphysema through immune profiling","authors":"P. Khedoe, Lijun Jia, Na Li, P. Hiemstra, F. Koning, J. Stolk","doi":"10.1183/23120541.lsc-2022.195","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.195","url":null,"abstract":"","PeriodicalId":232074,"journal":{"name":"Mechanisms of lung injury and repair","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126401800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An ex vivo model of cellular senescence and inflammaging in precision-cut lung slices 精确切割肺切片细胞衰老和炎症的离体模型
Mechanisms of lung injury and repair Pub Date : 2022-03-10 DOI: 10.1183/23120541.lsc-2022.162
M.C. Melo Narvaez, Q. Hu, M. Ansari, I. Angelidis, G. Stoleriu, A. Hilgendorff, A. Yildirim, H. Schiller, M. Koenigshoff, M. Lehmann
{"title":"An ex vivo model of cellular senescence and inflammaging in precision-cut lung slices","authors":"M.C. Melo Narvaez, Q. Hu, M. Ansari, I. Angelidis, G. Stoleriu, A. Hilgendorff, A. Yildirim, H. Schiller, M. Koenigshoff, M. Lehmann","doi":"10.1183/23120541.lsc-2022.162","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.162","url":null,"abstract":"","PeriodicalId":232074,"journal":{"name":"Mechanisms of lung injury and repair","volume":"200 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123556965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
In Vitro Simulation of Aerobic Exercise Effects in Neutrophils in Severe Asthma: Involvement of Kinins 有氧运动对重度哮喘中性粒细胞影响的体外模拟:激肽的参与
Mechanisms of lung injury and repair Pub Date : 2022-03-10 DOI: 10.1183/23120541.lsc-2022.23
M. A. R. Brandao-Rangel, R. Moraes Ferreira, Fabiana Regina da Silva Olímpio, C. Rocha, Rodolfo de Paula Vieira
{"title":"In Vitro Simulation of Aerobic Exercise Effects in Neutrophils in Severe Asthma: Involvement of Kinins","authors":"M. A. R. Brandao-Rangel, R. Moraes Ferreira, Fabiana Regina da Silva Olímpio, C. Rocha, Rodolfo de Paula Vieira","doi":"10.1183/23120541.lsc-2022.23","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.23","url":null,"abstract":"","PeriodicalId":232074,"journal":{"name":"Mechanisms of lung injury and repair","volume":"55 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123994452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum Levels of Surfactant Protein-B (SP-B) as biomarker in IPF and ILD-SSc 血清表面活性剂蛋白b (SP-B)水平作为IPF和ILD-SSc的生物标志物
Mechanisms of lung injury and repair Pub Date : 2022-03-10 DOI: 10.1183/23120541.lsc-2022.145
Gabriele Bartoli, A. Ricci, Andrea Mazza
{"title":"Serum Levels of Surfactant Protein-B (SP-B) as biomarker in IPF and ILD-SSc","authors":"Gabriele Bartoli, A. Ricci, Andrea Mazza","doi":"10.1183/23120541.lsc-2022.145","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.145","url":null,"abstract":"","PeriodicalId":232074,"journal":{"name":"Mechanisms of lung injury and repair","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121278116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of virus infection on the development of Bronchopulmonary Dysplasia (BPD) 病毒感染对支气管肺发育不良(BPD)发展的影响
Mechanisms of lung injury and repair Pub Date : 2022-03-10 DOI: 10.1183/23120541.lsc-2022.167
A. Dmitrieva, A. Hilgendorff, H. Adler
{"title":"The impact of virus infection on the development of Bronchopulmonary Dysplasia (BPD)","authors":"A. Dmitrieva, A. Hilgendorff, H. Adler","doi":"10.1183/23120541.lsc-2022.167","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.167","url":null,"abstract":"","PeriodicalId":232074,"journal":{"name":"Mechanisms of lung injury and repair","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130329285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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