Traditional Medicine Research最新文献

{"title":"Positive Effects of ‘AUM’ Chanting on Mental Health Well-Being","authors":"Anubha Pundir, Akshya Chauhan","doi":"10.35702/trad.10015","DOIUrl":"https://doi.org/10.35702/trad.10015","url":null,"abstract":"Chanting is an ancient practice that has been used for centuries to promote spiritual growth and emotional healing. Om chanting, in particular, is a powerful form of chanting that has gained popularity in recent years due to its reported positive effects on mental health. Mental health is a crucial aspect of well-being and has been linked with overall health and quality of life. The World Health Organization (WHO) defines mental health as a state of well-being where an individual realizes their potentials, copes with the stresses of life, works productively, and contributes to their community. However, mental health issues are on the rise globally, with depression, anxiety, and stress levels increasing among people in different age groups.","PeriodicalId":23192,"journal":{"name":"Traditional Medicine Research","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135675214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Vitro Establishment, Hydroponic, Salt Tolerance, Antifungal And Phytochemical Investigations In Important Sand Binder Medicinal Plant Ipomoea Pes-Caprae","authors":"S. Khan, Sara Rashed Salem Al Faraji, Mira Said Hamed Almukhaini, Ayaz Mohd, Farrukh Jamal, Samuel S D Premkumar, Priyanka Verma","doi":"10.35702/trad.10014","DOIUrl":"https://doi.org/10.35702/trad.10014","url":null,"abstract":"","PeriodicalId":23192,"journal":{"name":"Traditional Medicine Research","volume":"66 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85282942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dihydroartemisinin induces ferroptosis in pancreatic cancer cells by the regulation of survival prediction-related genes","authors":"Kai Guo, Ying-Ying Cao, Li-Chao Qian, Marcus Jerome Daniels, Ying Tian, Yuan Li, Li-Na Song, Zhong-Qiu Wang, Shuai Ren","doi":"10.53388/tmr20230618001","DOIUrl":"https://doi.org/10.53388/tmr20230618001","url":null,"abstract":"Background: Ferroptosis is a new therapeutic modality that holds promise for pancreatic cancer treatment. Dihydroartemisinin is the first generation of artemisinin derivatives with antimalarial activity, and it exerts anticancer activity through iron-dependent reactive oxygen species generation. This study assessed the potential value of dihydroartemisinin to induce ferroptosis in pancreatic cancer. Methods: The mRNA expression profiles, along with the corresponding clinical information of individuals diagnosed with pancreatic cancer, were acquired from publicly accessible repositories. We analyzed the association of ferroptosis-related gene expression with pancreatic cancer overall survival via The Cancer Genome Atlas. Utilizing molecular docking techniques, we evaluated the potential binding configurations of dihydroartemisinin with genes associated with ferroptosis. Moreover, in-vitro experiments were performed to verify these predicted outcomes. Results: In the The Cancer Genome Atlas cohort, there were significant differences in the expression levels of ten genes associated with ferroptosis when comparing pancreatic cancer tissues with normal tissues. Among them, a strong association between NQO1 expression and unfavorable prognosis was observed. Dihydroartemisinin can regulate target gene expression by interacting with the corresponding binding site, and a ferroptosis inhibitor could reverse the above events. Conclusion: The NQO1 gene, which is associated with ferroptosis, emerges as a robust and autonomous prognostic indicator for individuals with pancreatic cancer. Dihydroartemisinin may contribute to pancreatic cancer progression via the regulation of ferroptosis.","PeriodicalId":23192,"journal":{"name":"Traditional Medicine Research","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135497269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute kidney injury: microRNAs and new therapeutic opportunities for natural products","authors":"Ke Zhong, Han-Qing Zhang, Ya-Xuan Fang, Qiu-Mei Lan, Zi-Jun Zhou, Yan-Ru Zhao, Yan-Heng Qiao, Jie Li, Bo Yang","doi":"10.53388/tmr20230616001","DOIUrl":"https://doi.org/10.53388/tmr20230616001","url":null,"abstract":"","PeriodicalId":23192,"journal":{"name":"Traditional Medicine Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135103695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Huashi Jiedu decoction blocks cell cycle and inhibits EMT of gastric cells via LncRNA-p21","authors":"Xi Pang, Chao Shi, Le-Yin Zhang, Yu-Ting He, Qian-Ran Hong, Wei-Ye Lin, Lei-Tao Sun, Sheng-Liang Qiu","doi":"10.53388/tmr20230602001","DOIUrl":"https://doi.org/10.53388/tmr20230602001","url":null,"abstract":"Background: MicroRNAs and traditional Chinese medicine have emerged as pivotal regulators in the progression of gastric carcinoma. Huashi Jiedu decoction has been clinically used to enhance the quality of life in gastric carcinoma patients. Therefore, the present study aimed to elucidate the involvement of MicroRNAs and Huashi Jiedu decoction in gastric carcinoma metastasis and investigate their regulatory mechanisms in anti-tumor effects. Methods: Subsequently, the effect of Huashi Jiedu decoction on gastric carcinoma cell metastasis and proliferation was verified using cell counting kit-8, flow cytometry, wounding healing, and Transwell assays. LncRNA-p21 knockdown cells were successfully established in BGC-823 and MGC-803 cell lines. Mouse models inoculated with MGC-803 cells were generated, and the cellular morphology in tissues was assessed using hematoxylin staining. Additionally, western blot and immunohistochemistry analysis were performed to evaluate the expression of epithelial-mesenchymal transition-related proteins, with real-time PCR validation conducted in both in vitro and in vivo settings. Results: Network pharmacology revealed a close association between proteins involved in the epithelial-mesenchymal transition process and LncRNA-p21 in gastric carcinoma, consistent with the downregulated expression of E-cadherin, N-cadherin, and Twist following LncRNA-p21 knockdown. Cell counting kit-8 and flow cytometry assays confirmed that Huashi Jiedu decoction exhibited concentration-dependent cytotoxicity, effectively inhibiting the distant metastasis of gastric carcinoma cells in wound healing and invasion experiments. Treatment with Huashi Jiedu decoction resulted in increased expression of E-cadherin, N-cadherin, and LncRNA-p21 in both in vitro and in vivo models, as validated by western blot, real-time PCR, and immunohistochemistry. Conclusion: Collectively, our findings demonstrate that Huashi Jiedu decoction suppresses epithelial-mesenchymal transition and inhibits gastric carcinoma invasion and metastasis both in vivo and in vitro through the knockdown of LncRNA-p21, corroborating the initial findings from our network pharmacology analysis.","PeriodicalId":23192,"journal":{"name":"Traditional Medicine Research","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135494952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acupuncture Modulation with Extremely Low Electromagnetic Frequency Patches","authors":"Jevdic A, Jevdic D, Brasovan N, Brasovan S","doi":"10.35702/trad.10013","DOIUrl":"https://doi.org/10.35702/trad.10013","url":null,"abstract":"","PeriodicalId":23192,"journal":{"name":"Traditional Medicine Research","volume":"8 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2022-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88877492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Gastroduodenal Disease with Helicobacter Pylori in the Region of Tiaret, Algeria","authors":"Souhila Tabak, M. Miara, H. Bendif, L. A. Vitali","doi":"10.35702/trad.10012","DOIUrl":"https://doi.org/10.35702/trad.10012","url":null,"abstract":"","PeriodicalId":23192,"journal":{"name":"Traditional Medicine Research","volume":"60 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2022-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88395691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improvement of Self-Perceived Tinnitus and Speech Discrimination in Noise by Lyophilized Powder of Enzymolyzed Honeybee (Apis melifera) Larvae in Older Adults with Age-Related Hearing Loss: A Double-Blind Placebo-Controlled, Randomized Study","authors":"M. Aoki, Hiroshi Okuda, Natsuko Obara","doi":"10.35702/trad.10011","DOIUrl":"https://doi.org/10.35702/trad.10011","url":null,"abstract":"","PeriodicalId":23192,"journal":{"name":"Traditional Medicine Research","volume":"50 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2022-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88508968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhibitory Effect of Rhei Rhizoma Constituents on the Cortisol Production in ACTH-Stimulated Bovine Adrenal Fasciculata Cells","authors":"N. Kuwabara, Y. Matsuo, Tsuyoshi Ueki, Yuki Nakamura, Nanami Kase, Taisuke Okayasu, Y. Mimaki, E. Tachikawa, Shinji Sato, Haruki Yamada, S. Nakagawa","doi":"10.35702/trad.10010","DOIUrl":"https://doi.org/10.35702/trad.10010","url":null,"abstract":"","PeriodicalId":23192,"journal":{"name":"Traditional Medicine Research","volume":"4 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76766828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wild Edible Vegetables Used for Health Benefit by Rural People of Gondia District in Maharashtra State, India","authors":"T. Nimbekar, Dilip Sanghi","doi":"10.35702/trad.10009","DOIUrl":"https://doi.org/10.35702/trad.10009","url":null,"abstract":",","PeriodicalId":23192,"journal":{"name":"Traditional Medicine Research","volume":"55 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2022-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82271318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}