ABC Heart Fail Cardiomyop最新文献

{"title":"Evidence Based Treatment of Heart Failure: Challenges of Drug Access","authors":"L. Einsfeld, Diogo Pilger, Cassiela Roman","doi":"10.36660/abchf.20230049","DOIUrl":"https://doi.org/10.36660/abchf.20230049","url":null,"abstract":"","PeriodicalId":231546,"journal":{"name":"ABC Heart Fail Cardiomyop","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139300854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urgent Right Heart Catheterization in Cardiogenic Shock: Let us Spread this Idea","authors":"S. Savaris, Suellen R. R. Siqueira, I. C. V. Lima","doi":"10.36660/abchf.20230076","DOIUrl":"https://doi.org/10.36660/abchf.20230076","url":null,"abstract":"Cardiogenic shock (CS) is defined by the presence of signs and symptoms of low tissue perfusion associated with systolic blood pressure (BP) < 90mmHg, according to the European Society of Cardiology. Within the different types of shock - cardiogenic, distributive, hypovolemic, and mixed - CS is responsible for up to 66% of shock cases in intensive care units and occurs due to poor perfusion secondary to low cardiac output. The most prevalent etiology is ST-elevation myocardial infarction (STEMI); other causes include acute chronic heart failure, valvular diseases, and arrhythmias. 1,2 In-hospital mortality from CS associated with STEMI can reach 36% in cases not associated with a heart attack, 31%. Furthermore, effective treatment is related to understanding the disease mechanism and classifying the patient into phenotypes, which will impact the implemented therapy.","PeriodicalId":231546,"journal":{"name":"ABC Heart Fail Cardiomyop","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139294596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship of MAPH Score with Left Ventricular Apical Thrombus and Adverse Events in Patients with Acute Anterior ST-Elevation Myocardial Infarction","authors":"U. Küçük, Meltem Altınsoy","doi":"10.36660/abchf.20230060","DOIUrl":"https://doi.org/10.36660/abchf.20230060","url":null,"abstract":"","PeriodicalId":231546,"journal":{"name":"ABC Heart Fail Cardiomyop","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139293995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arrhythmogenic Left Ventricular Cardiomyopathy – State of Art: From Genotype to Phenotype","authors":"Ana Flávia Malheiros Torbey, E. Nascimento, N. S. Nunes, Adriana Bastos Carvalho, Daniel Gama das Neves, Raquel Germer Toja Couto, Sandra Vitória Thuler Pimentel, Eduarda Corrêa Maia, E. T. Mesquita","doi":"10.36660/abchf.20230035","DOIUrl":"https://doi.org/10.36660/abchf.20230035","url":null,"abstract":"Arrhythmogenic cardiomyopathy with exclusive or predominant involvement of the left ventricle has been described recently. It has a heterogeneous genetic basis with different clinical phenotypes ranging from ventricular arrhythmias and sudden death (SD), symptoms suggestive of acute myocarditis with chest pain and troponin elevation, symptoms of heart failure, to asymptomatic patients. A high level of suspicion is needed for a correct diagnosis and implementation of a genotype-based therapy, to prevent its most feared complication, SD. This review aims to describe arrhythmogenic left ventricular cardiomyopathy as a genetic heart disease, with initial and/or predominant involvement of the left ventricle and its varied phenotypic expression, providing a basis for clinical reasoning and “red-flags” for the diagnosis, as well as for SD risk stratification.","PeriodicalId":231546,"journal":{"name":"ABC Heart Fail Cardiomyop","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123865498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tachycardiomyopathies","authors":"L. Beck-da-Silva, Andreia Biolo","doi":"10.36660/abchf.20230044","DOIUrl":"https://doi.org/10.36660/abchf.20230044","url":null,"abstract":"","PeriodicalId":231546,"journal":{"name":"ABC Heart Fail Cardiomyop","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125626772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare and Ultra-Rare Diseases as Causes of Cardiomyopathy","authors":"D. Ávila, Sandra Marques e Silva","doi":"10.36660/abchf.20230032","DOIUrl":"https://doi.org/10.36660/abchf.20230032","url":null,"abstract":"Several definitions of rare disease have emphasized the low prevalence of genetic diseases that can affect cardiac tissues and cause high psychosocial suffering due to the challenging diagnostic process and the high costs of complementary tests and specific therapies. In addition, there is the need for referral centers with different medical specialists, as well as nurses, social workers, psychologists, physiotherapists, among other professionals. With the rapid advances in genetics and precision medicine, associated with the emergence of specific therapeutic molecules (orphan drugs), many rare diseases are no longer “hidden” in pages’ footnotes, and their diagnoses cannot be neglected. The first step is to understand their physiopathogenesis, clinical signs and symptoms, and complementary diagnosis tools including genotyping. This review aims to present objective and important information to contribute to the investigation of the cardiovascular involvement in some of the rare genetic diseases.","PeriodicalId":231546,"journal":{"name":"ABC Heart Fail Cardiomyop","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133300623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Era of Personalized Medicine in Cardiomyopathies","authors":"D. Ávila, E. T. Mesquita","doi":"10.36660/abchf.20230039","DOIUrl":"https://doi.org/10.36660/abchf.20230039","url":null,"abstract":"Learning about cardiomyopathies has become more in-depth in recent years. Thus, several views of specialists from Brazil are present in this edition of ABC Heart Failure & Cardiomyopathy, of the ABC Family of Arquivos Brasileiros de Cardiologia (ABC Cardiol), from the most common etiologies to the rarest and ultra-rare ones, with their systemic repercussions, including toxic, genetic, peripartum, stress, diabetes, collagenosis, cardiogenetic interaction, as well as a vision of the future with artificial intelligence and 3D printing in cardiomyopathies. Advances in imaging such as coronary computed tomography angiography in the non-invasive diagnosis of coronary artery disease, magnetic resonance imaging and its various specific evaluations of cardiomyopathies, nuclear medicine in microvascular disease and non-invasive diagnosis of transthyretin amyloidosis, and genetic tests have facilitated the recognition of different phenotypes. Moreover, based on the genotype of a given case, an entire family can also be identified related to preexisting clinical syndromes. Interaction between specialties and heart teams have improved care, disease management, and assistance of affected families. Accordingly, follow-up with a geneticist and genetic counseling are imperative in the era of personalized medicine. Genetic sequencing of patients in the context of advances in cardiac imaging has indicated a new perspective for these concepts. The “MOGES” classification of cardiomyopathies, since 2014, has emphasized extracardiac manifestations, familial inheritance pattern, and genetic etiology.1 Recent clinical studies have described cohorts with specific variants that show subtypes of different phenotypes. Indeed, in the coming years, new classifications of cardiomyopathies and clinical conduct are plausible. Follow-up by multidisciplinary teams specializing in cardiogenetics demonstrates better communication and management of variants of uncertain significance that may be relevant in the clinical expression of cardiomyopathies and may reclassify them. Furthermore, today we can rely on in vitro techniques with targeted gene identification to assist families with variants.2-5 Genetics is a useful tool in diagnosis, risk stratification, and family management. Currently, there are guidelines with wellestablished recommendations regarding the application of","PeriodicalId":231546,"journal":{"name":"ABC Heart Fail Cardiomyop","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116738893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis and Treatment of Hypertrophic Cardiomyopathy","authors":"F. Saraiva, F. Fernandes, M. Romano, Juliano Cardoso, Marília Taily Soliani, Mariani Mendes Madison, A. Schmidt, M. Simões","doi":"10.36660/abchf.20230040","DOIUrl":"https://doi.org/10.36660/abchf.20230040","url":null,"abstract":"","PeriodicalId":231546,"journal":{"name":"ABC Heart Fail Cardiomyop","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121747170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic Counseling and Pedigree in Cardiomyopathies – the Role of the Clinical Geneticist","authors":"D. Ávila, Frank Nunes, Raquel Germer, Ana Flávia Malheiros Torbey","doi":"10.36660/abchf.20230023","DOIUrl":"https://doi.org/10.36660/abchf.20230023","url":null,"abstract":"","PeriodicalId":231546,"journal":{"name":"ABC Heart Fail Cardiomyop","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130732413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in Diagnosis and Treatment of Cancer Immunotherapy and CAR-T Cell–Related Myocarditis","authors":"A. Macedo, Aurea Grippa, K. Luz, Nathalia Coelho de Castro Nunes, S. Mangini","doi":"10.36660/abchf.20230025","DOIUrl":"https://doi.org/10.36660/abchf.20230025","url":null,"abstract":"","PeriodicalId":231546,"journal":{"name":"ABC Heart Fail Cardiomyop","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121141627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}