Tijdschrift Voor Geneeskunde最新文献_第5页

Uit de oude doos: Praatjes in de wind - juni 1947 来自旧盒子：风中的谈话--1947 年 6 月

Tijdschrift Voor Geneeskunde Pub Date : 2023-12-19 DOI: 10.47671/tvg.77.21.182

B. Vandekerkhove

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De noodzaak aan data voor artificiële intelligentie in de geneeskunde 医学人工智能对数据的需求

Tijdschrift Voor Geneeskunde Pub Date : 2023-12-18 DOI: 10.47671/tvg.79.23.110

M. Lingier, N. Naessens, E. Ranschaert, K. Verstraete

{"title":"De noodzaak aan data voor artificiële intelligentie in de geneeskunde","authors":"M. Lingier, N. Naessens, E. Ranschaert, K. Verstraete","doi":"10.47671/tvg.79.23.110","DOIUrl":"https://doi.org/10.47671/tvg.79.23.110","url":null,"abstract":"The need for data for artificial intelligence in medicine In recent decades, there has been a digital revolution in medicine, with an increasing integration of innovative technologies across different disciplines in the medical world. Artificial intelligence (AI), in particular, has the potential to have a groundbreaking impact on the healthcare of the future. However, the core of this promising technology heavily relies on data. Relevant literature was systematically and structurally searched through the databases of PubMed and Embase. Interviews were conducted with experts based on the insights and considerations from the literature. These interviews formed the foundation of this paper. Finally, the interviews were supported by relevant websites and literature found through Google Scholar. To develop a generalizable algorithm, the used data should not only have a high quality, but must also be numerous and diverse. However, there is not necessarily a need for more data, but rather for accessibility of the data. In clinical practice, a standardized format to store data is lacking. Furthermore, the data are scattered across different centres, with data-sharing heavily protected by the GDPR. There is a need for uniform and linkable data that can be collected from multiple healthcare institutions in a structured and protected manner using a centralized data platform. This data should have a high quality and must be sufficient in number to develop a robust and representative algorithm. The entire process must comply with the strict obligations imposed by the GDPR, ensuring the protection of the patients’ privacy.","PeriodicalId":23124,"journal":{"name":"Tijdschrift Voor Geneeskunde","volume":"15 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139173637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Acute tubulusnecrose na zoledronaat voor de behandeling van osteoporose: casusbespreking en literatuurstudie 唑来膦酸钠治疗骨质疏松症后出现急性肾小管坏死：病例报告和文献综述

Tijdschrift Voor Geneeskunde Pub Date : 2023-12-15 DOI: 10.47671/tvg.79.23.101

K. Denewet, M. Dejaeger, E. Gielen

{"title":"Acute tubulusnecrose na zoledronaat voor de behandeling van osteoporose: casusbespreking en literatuurstudie","authors":"K. Denewet, M. Dejaeger, E. Gielen","doi":"10.47671/tvg.79.23.101","DOIUrl":"https://doi.org/10.47671/tvg.79.23.101","url":null,"abstract":"Acute tubular necrosis following zoledronic acid for the treatment of osteoporosis: case report and literature review\u0000\u0000 \u0000\u0000Zoledronic acid is a potent intravenous bisphosphonate widely used in the treatment of osteoporosis, amongst others. Bisphosphonate nephrotoxicity has been described for a long time, is dose-dependent and is more common when used in oncologic indications.\u0000\u0000 \u0000\u0000A case of acute tubular necrosis following a treatment with zoledronate in a patient with osteoporosis is described. An 88-year-old male patient was admitted with general weakness and recurrent falls, 10 days after the fourth, annual administration of 5 mg of zoledronic acid. Acute on chronic kidney injury with a creatinine of 6.77 mg/dL compared to the baseline of 1.7 mg/dL was established. There was a temporary requirement for dialysis because of metabolic complications. The diagnosis of toxic acute tubular necrosis was made. After 6 weeks, there was a gradual improvement to a creatinine of 2.64 mg/dL.\u0000\u0000 \u0000\u0000The case description is followed by a description of the mechanisms of nephrotoxicity of zoledronic acid and by a literature overview about its prevention in osteoporosis. Measurement of the serum creatinine before the infusion of zoledronic acid, awareness of possible nephrotoxicity and preventive measures are important to prevent acute kidney failure in patients with osteoporosis treated with zoledronic acid. Given the clearly proven effect of zoledronic acid on the fracture risk, the very low risk of renal side effects is certainly not a reason to avoid zoledronic acid in patients with a creatinine clearance above 35 ml/min according to the Cockcroft-Gault equation (CG).","PeriodicalId":23124,"journal":{"name":"Tijdschrift Voor Geneeskunde","volume":"51 S12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138999900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Al minstens 30 medisch-psychiatrische units in Nederland: waarop wacht Vlaanderen nog? 荷兰已有至少 30 个精神病医疗单位：佛兰德斯还在等什么？

Tijdschrift Voor Geneeskunde Pub Date : 2023-12-12 DOI: 10.47671/tvg.79.23.115

F. Van Den Eede, C. Pinto, D. Peeters, M. van Schijndel

{"title":"Al minstens 30 medisch-psychiatrische units in Nederland: waarop wacht Vlaanderen nog?","authors":"F. Van Den Eede, C. Pinto, D. Peeters, M. van Schijndel","doi":"10.47671/tvg.79.23.115","DOIUrl":"https://doi.org/10.47671/tvg.79.23.115","url":null,"abstract":"At least 30 medical-psychiatric units in The Netherlands: what is Flanders waiting for?\u0000\u0000 \u0000\u0000The medical-psychiatric unit (MPU) constitutes an important integrated health service for the diagnostic assessment and the treatment of patients with co-occurring somatic and psychiatric morbidity when the somatic problems are too complex for the psychiatric department or the psychiatric disorder complicates or prevents treatment at a medical ward. There are different types of MPU based on the level of acuity, as well as on the objectives and the service providing the actual care.\u0000\u0000 \u0000\u0000As yet and in contrast to The Netherlands, the United States and many other countries, no similar combined health service is operational in Flanders (Belgium). With the aim to improve the quality of care in case of any such moderate to severe comorbidity and to ensure the safety of care and the staff, the authors deem it advisable to set up MPUs in Flemish general and/or university hospitals.\u0000\u0000 \u0000\u0000Indisputably, any MPU is a challenging and multifaceted endeavour. Their efficiency and treatment outcomes require further research, most preferably studies evaluating views and findings obtained in clinical practice. Also, funding and management frameworks need to be developed to facilitate the organisation and operation of such complex care units.","PeriodicalId":23124,"journal":{"name":"Tijdschrift Voor Geneeskunde","volume":"13 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139010147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hoe waarheidsgetrouw zijn verklaringen over middelengebruik in het rijgeschiktheidsonderzoek? 驾驶考试中有关药物使用的陈述的真实性如何？

Tijdschrift Voor Geneeskunde Pub Date : 2023-12-08 DOI: 10.47671/tvg.79.23.084

B. Van Rafelghem, A. Van Goethem, W. Jacobs

{"title":"Hoe waarheidsgetrouw zijn verklaringen over middelengebruik in het rijgeschiktheidsonderzoek?","authors":"B. Van Rafelghem, A. Van Goethem, W. Jacobs","doi":"10.47671/tvg.79.23.084","DOIUrl":"https://doi.org/10.47671/tvg.79.23.084","url":null,"abstract":"How truthful are statements about substance use in the fitness to drive examination?\u0000\u0000 \u0000\u0000In Belgium, the court can order a fitness to drive examination on indication. One is not fit to drive if there has been excessive alcohol and/or drug use in the past 6 months. Chronic excessive alcohol use corresponds to an average consumption of ≥ 6 units per day or ≥ 42 units per week over several months. Toxicologically, 30 pg/mg ethylglucuronide (direct alcohol marker) in scalp hair strongly suggests this. For drugs, it is sufficient to demonstrate this substance in one of the samples.\u0000\u0000 \u0000\u0000The anamnesis and toxicology were compared with a McNemar test. The sensitivity, specificity and positive/negative predictive value of the anamnesis as a diagnostic test were calculated.\u0000\u0000 \u0000\u0000People are more likely to be unfit to drive based on the toxicological analysis than based on the anamnesis (respectively 60% versus 40%). The greatest discrepancy is seen regarding alcohol consumption. In addition, toxicologically more cases of drug use were detected. This study shows that statements regarding alcohol and drug use within the fitness to drive examination are not reliable.","PeriodicalId":23124,"journal":{"name":"Tijdschrift Voor Geneeskunde","volume":"9 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138587712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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E-book: Verloskunde - Uitgave 2023 电子书：产科》--第 2023 期

Tijdschrift Voor Geneeskunde Pub Date : 2023-12-07 DOI: 10.47671/tvg.79.23.e020

S. Vos, B. Van den Bergh, H. Roels, D. Martens, H. Kindermans, T.S. Nawrot, J. Rombaut, N. Coryn, R. Salihi, P. Tummers, Y. Biesemans, E. Roets, M. Baetens, K. Roelens, B. Menten, A. Vandewal, A. Thaens, S. Fransis, M. Finoulst, P. Vankrunkelsven, A. Van Tongerloo, H. Verdin, B. Blaumeiser, L. Polster, P. Coucke, S. Janssens

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Primair adrenaal lymfoom 原发性肾上腺淋巴瘤

Tijdschrift Voor Geneeskunde Pub Date : 2023-12-04 DOI: 10.47671/tvg.79.23.080

S. Buyse, W. Daneels, B. Lapauw

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Welkom aan onze nieuwe hoofdredactie! 欢迎我们的新主编

Tijdschrift Voor Geneeskunde Pub Date : 2023-12-01 DOI: 10.47671/tvg.79.23.125

J. Heyrman

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Zorg dragen 关爱

Tijdschrift Voor Geneeskunde Pub Date : 2023-12-01 DOI: 10.47671/tvg.79.23.121

P. Lacor

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Folia Pharmacotherapeutica december 2023 Folia Pharmacotherapeutica 2023 年 12 月

Tijdschrift Voor Geneeskunde Pub Date : 2023-11-30 DOI: 10.47671/tvg.79.23.120

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