The Korean Journal of Blood Transfusion最新文献_第8页

Improving Storage Policy in Korean Public Cord Blood Banks: Comparison of Quality between Long-Term and Short-Term Storage of Cord Blood 韩国公共脐带血库储存政策的改进:长期与短期脐带血储存质量的比较

The Korean Journal of Blood Transfusion Pub Date : 2020-08-31 DOI: 10.17945/kjbt.2020.31.2.119

Mi Nam Lee, K. Kim, Byoung-Gwon Kim, Ri-Young Goh, Jun Nyun Kim

引用次数: 0

A Simple Comment of Trauma-Induced Coagulopathy and Massive Transfusion 外伤性凝血病与大量输血简评

The Korean Journal of Blood Transfusion Pub Date : 2020-08-31 DOI: 10.17945/kjbt.2020.31.2.101

Dae-Sang Lee

{"title":"A Simple Comment of Trauma-Induced Coagulopathy and Massive Transfusion","authors":"Dae-Sang Lee","doi":"10.17945/kjbt.2020.31.2.101","DOIUrl":"https://doi.org/10.17945/kjbt.2020.31.2.101","url":null,"abstract":"A massive blood transfusion is a challenging situation that can be encountered in the treatment of trauma patients. Under these circumstances, clinicians should conduct appropriate blood transfusions using the massive transfusion protocol, and make efforts to prepare and apply these protocols to the systems of each hospital in advance. In addition, the effect of massive bleeding on the body highlights the need to understand why fresh frozen plasma and platelets, as well as packed red blood cells (pRBC), are needed during massive transfusion. In hemorrhagic patients, blood pressure maintenance through transfusion is an important part, but above all, efforts to control sustained bleeding by controlling and treating the bleeding itself are more important. This is because patients need to recover their organs after early resuscitation by minimizing the side effects of transfusion. No research has been done to compare the restrictive transfusion and liberal transfusion strategies in patients requiring massive transfusion. On the other hand, various studies suggest that it is more advantageous to apply a liberal blood transfusion strategy in patients with severe or older age. Nevertheless, there has been insufficient research to apply it generally. Therefore, for patients whose resuscitation has been performed by applying a massive transfusion protocol, a reasonable treatment approach would be to shift to a strategy to supplement poor coagulation factors through a goal-directed transfusion. (Korean J Blood Transfus 2020;31:101-108)","PeriodicalId":231122,"journal":{"name":"The Korean Journal of Blood Transfusion","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116503984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Weak D Type 102 Found in a Family Study: The First Case in Korea 在家庭研究中发现的弱D型102:韩国的第一例

The Korean Journal of Blood Transfusion Pub Date : 2020-08-31 DOI: 10.17945/kjbt.2020.31.2.153

Beomki Lee, Yoo Na Chung, HongBi Yu, Tae Yeul Kim, Kwang-Mo Choi, D. Cho

{"title":"Weak D Type 102 Found in a Family Study: The First Case in Korea","authors":"Beomki Lee, Yoo Na Chung, HongBi Yu, Tae Yeul Kim, Kwang-Mo Choi, D. Cho","doi":"10.17945/kjbt.2020.31.2.153","DOIUrl":"https://doi.org/10.17945/kjbt.2020.31.2.153","url":null,"abstract":"Weak D type 102 allele (RHD*01W.102) carrying a missense variant (c.73A>T, p.Ile25Phe) in exon 1 of the RHD has not been reported in Koreans to date. This is the first report of the weak D type 102 allele in the Korean population. The proposita, a 35-year-old woman, showed a serological weak D phenotype in routine RhD typing. Sequencing of all 10 RHD exons and zygosity testing targeting the hybrid Rhesus box revealed this proposita to harbor the weak D type 102 allele, as well as an RHD deletion (RHD*01W.102/RHD*01N.01). Family studies showed that the weak D type 102 allele was also present in her father and older brother (both assumed to be RHD*01W.102/RHD*01) but not in her mother and oldest brother (both assumed to be RHD*01/RHD*01N.01). In silico analysis of the replacement of isoleucine by phenylalanine at position 25 was done with PolyPhen-2, SIFT, and PROVEAN. While PolyPhen-2 predicted the variant as benign, SIFT and PROVEAN predicted it as damaging and deleterious, respectively, suggesting RHD c.73A>T (I25F) as the cause of serologic weak D phenotype. This patient should be treated as D-negative, when transfusion is needed. (Korean J Blood Transfus 2020;31:153-158)","PeriodicalId":231122,"journal":{"name":"The Korean Journal of Blood Transfusion","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115338966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of HIV RNA Genotypes and Quantitative Values of HIV NAT Reactive Blood Donations HIV NAT反应性献血者HIV RNA基因型及定量分析

The Korean Journal of Blood Transfusion Pub Date : 2020-08-31 DOI: 10.17945/kjbt.2020.31.2.141

Jungwon Kang, J. Kang, Dae Ho Ko, M. Youn, So‐Yong Kwon

{"title":"Analysis of HIV RNA Genotypes and Quantitative Values of HIV NAT Reactive Blood Donations","authors":"Jungwon Kang, J. Kang, Dae Ho Ko, M. Youn, So‐Yong Kwon","doi":"10.17945/kjbt.2020.31.2.141","DOIUrl":"https://doi.org/10.17945/kjbt.2020.31.2.141","url":null,"abstract":"Background: The Korean Red Cross adopted HIV NAT for blood donor screening in 2005 using a minipool assay. In June 2012, the NAT system was replaced with the individual assay. This study examined the characteristics of HIV NAT reactive blood donors to determine if there was any difference in their features between 10 years ago and later. Methods: This study analyzed the HIV RNA quantitative values and the distribution of HIV subtypes using 118 HIV NAT positive blood donations (37 in 2007, 20 in 2008, 32 in 2017 and 29 in 2018). Results: No significant variations of the quantitative values of HIV RNA and the distribution of HIV subtypes 10 years ago and later were observed. This study failed to produce quantitative values of three samples due to the low titer. The mean titer of HIV RNA of the remaining 115 samples were 5.14×10 IU/mL. The dominant HIV subtype of the HIV NAT reactive donors was B showing 54.2% (64/118). Approximately 5.9% (7/118) of the samples showed the HIV subtype C. Forty-seven samples (39.8%) showed the circulating recombinant form (CRF). Conclusion: The rate of HIV subtype B in this study (54.2%) has decreased compared to the results of the past study (95.2%). Some of the cases showing CRF were identified as B in the past study because CRF3, 8, 9, 14, and 15 are recombinant forms, including subtype B. (Korean J Blood Transfus 2020;31:141-152)","PeriodicalId":231122,"journal":{"name":"The Korean Journal of Blood Transfusion","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122885213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the Automated Analyzer AutoVue Innova for Blood Group Typing: Clinical Implementation at a Tertiary Hospital over 2 Years 自动血型分析仪AutoVue Innova在某三级医院2年临床应用的评价

The Korean Journal of Blood Transfusion Pub Date : 2020-08-31 DOI: 10.17945/kjbt.2020.31.2.131

Seong-Eun Ryu, Hyun-Ji Lee, Hyerin Kim, Kyung-Hwa Shin, Hyung-Hoi Kim

{"title":"Evaluation of the Automated Analyzer AutoVue Innova for Blood Group Typing: Clinical Implementation at a Tertiary Hospital over 2 Years","authors":"Seong-Eun Ryu, Hyun-Ji Lee, Hyerin Kim, Kyung-Hwa Shin, Hyung-Hoi Kim","doi":"10.17945/kjbt.2020.31.2.131","DOIUrl":"https://doi.org/10.17945/kjbt.2020.31.2.131","url":null,"abstract":"Background: An increasing number of blood banks use an automated analyzer in ABO blood typing to reduce the high workload and impact of human error. On the other hand, the automated system often causes ABO discrepancies, where cell and serum typing do not match. Hence, the manual method is used for confirmation. This study evaluated the appropriateness of retesting with the manual method. In addition, the causes of ABO discrepancies were analyzed. Methods: A total of 77,590 blood samples were tested with the AutoVue Innova for ABO typing. Among them, 1280 samples were retested manually due to ABO discrepancies. The causes of the discrepancies were analyzed further through additional tests. The serum reaction grades in both methods were compared. Results: ABO typing of 76,906 samples (99.12%), which included 596 manually confirmed samples could be confirmed by the AutoVue system, while 403 samples (0.52%) continued to yield discrepant results. Weak serum reactions in the AutoVue system were observed, as previously reported. One hundred and thirty samples (66.7%), which were graded 0.5+ in the automated analyzer, yielded a negative serum reaction in the manual method, showing a greater serum reaction with the AutoVue system than with the manual method. Conclusion: The AutoVue Innova performs reliably for blood typing. On the other hand, the manual method is still useful as retesting to address the ABO discrepancies and weak or strong serum reactions. In particular, it is important to confirm samples with 0.5+ grade serum reactions manually. (Korean J Blood Transfus 2020; 31:131-140)","PeriodicalId":231122,"journal":{"name":"The Korean Journal of Blood Transfusion","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133943994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Transfusion in RhD Mismatch Hematopoietic Stem Cell Transplantation 输血在RhD错配造血干细胞移植中的应用

The Korean Journal of Blood Transfusion Pub Date : 2020-08-31 DOI: 10.17945/kjbt.2020.31.2.159

D. Kim, Kyung-Hee Kim, Y. Seo, P. Park, J. Ahn, J. Seo

引用次数: 1

Transfusion in ABO-Incompatible Solid Organ Transplantation abo血型不相容的实体器官移植输血

The Korean Journal of Blood Transfusion Pub Date : 2020-04-30 DOI: 10.17945/kjbt.2020.31.1.70

Hyungsuk Kim, Dae-Hyun Ko

引用次数: 3

The Effect of the Transfusion Indication Verification Program on the Appropriateness of Fresh Frozen Plasma Transfusion 输血适应症验证程序对新鲜冷冻血浆输血适宜性的影响

The Korean Journal of Blood Transfusion Pub Date : 2020-04-30 DOI: 10.17945/kjbt.2020.31.1.43

S. Kim, G. Bae, Hye Ryun Lee

{"title":"The Effect of the Transfusion Indication Verification Program on the Appropriateness of Fresh Frozen Plasma Transfusion","authors":"S. Kim, G. Bae, Hye Ryun Lee","doi":"10.17945/kjbt.2020.31.1.43","DOIUrl":"https://doi.org/10.17945/kjbt.2020.31.1.43","url":null,"abstract":"a computerized order system in February 2018. Physicians should select the indication during transfusion order. In January 2019, the warning pop-up additionally applied for informing whether or not the coagulation test results correspond to FFP transfusion indications. We investigated the effects of a new applied program on the appropriateness of FFP transfusion. Methods: By comparing the appropriateness of transfusion before applying the transfusion indication data-entry, we investigated whether there were improvements of appropriateness after applying the transfusion indication data-entry and after applying the warning pop-up. We compared the percentages of performing pre-transfusion coagulation tests and transfusion among FFP requests before and after applying the warning pop-up. Results: After applying the transfusion indication data-entry, the appropriateness improved from 54.5% to 66.7%. The appropriateness of the surgery department was the lowest compared with that of the medical departments and emergency departments. The warning pop-up would be effective to induce pre-transfusion coagulation tests from surgery departments and emergency department. However, there was no further improvement in the appropriateness. Many requests from the surgery departments did not lead to transfusion. As the results of the analysis conducted by dividing each department that belonged to surgery departments, we could determine the wrong transfusion practice specific to each department. Conclusion: The transfusion indication data-entry contributed to improving the appropriateness of FFP transfusion. Department-specific education and real-time auditing are needed for further improvement. (Korean 2020;31:43-54)","PeriodicalId":231122,"journal":{"name":"The Korean Journal of Blood Transfusion","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127180636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How Does COVID19 Affect Blood Transfusion and Blood Management? covid - 19如何影响输血和血液管理?

The Korean Journal of Blood Transfusion Pub Date : 2020-04-30 DOI: 10.17945/kjbt.2020.31.1.1

Y. Lim, D. Seo, Y. Hwang.

引用次数: 2

Suggestions for Specialization and Enhancing Capacity in National Blood Services 国家血液服务专业化和能力提升的建议

The Korean Journal of Blood Transfusion Pub Date : 2020-04-30 DOI: 10.17945/kjbt.2020.31.1.5

Hyun Ok Kim, Y. Cha, Q. Park, E. Choi, Y. Lim, D. Seo, Y. Hwang.

引用次数: 1