{"title":"Real-World Evidence and Hepatitis C","authors":"M. Fried, D. Nelson","doi":"10.1007/7355_2019_63","DOIUrl":"https://doi.org/10.1007/7355_2019_63","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84767677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lysine-Specific Histone Demethylases 1/2 (LSD1/2) and Their Inhibitors","authors":"Takayoshi Suzuki","doi":"10.1007/7355_2019_74","DOIUrl":"https://doi.org/10.1007/7355_2019_74","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80594108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Discovery of Ledipasvir (GS-5885): The Potent Once-Daily Oral HCV NS5A Inhibitor in the Single-Tablet Regimen Harvoni®","authors":"J. Link","doi":"10.1007/7355_2019_66","DOIUrl":"https://doi.org/10.1007/7355_2019_66","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":"85 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83215724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guoqiang Wang, Jun Ma, Li-juan Jiang, Yonghua Gai, Jiang Long, Bin Wang, K. McDaniel, Y. Or
{"title":"Discovery and Development of the Next-Generation HCV NS3 Protease Inhibitor Glecaprevir","authors":"Guoqiang Wang, Jun Ma, Li-juan Jiang, Yonghua Gai, Jiang Long, Bin Wang, K. McDaniel, Y. Or","doi":"10.1007/7355_2018_55","DOIUrl":"https://doi.org/10.1007/7355_2018_55","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82813264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"NS5A as a Target for HCV Drug Discovery","authors":"Donald R. O'boyleii, Min Gao","doi":"10.1007/7355_2018_45","DOIUrl":"https://doi.org/10.1007/7355_2018_45","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82768842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Targeting the Zinc-Dependent Histone Deacetylases (HDACs) for Drug Discovery","authors":"A. Ganesan","doi":"10.1007/7355_2019_68","DOIUrl":"https://doi.org/10.1007/7355_2019_68","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87956869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evan P. Stater, Magdalena Skubal, R. Tamura, J. Grimm
{"title":"The Present and Future of Optical Imaging Technologies in the Clinic: Diagnosis and Therapy","authors":"Evan P. Stater, Magdalena Skubal, R. Tamura, J. Grimm","doi":"10.1007/7355_2019_84","DOIUrl":"https://doi.org/10.1007/7355_2019_84","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86219334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Discovery of the Hepatitis C Virus","authors":"M. Houghton","doi":"10.1007/7355_2018_53","DOIUrl":"https://doi.org/10.1007/7355_2018_53","url":null,"abstract":"","PeriodicalId":23098,"journal":{"name":"Topics in Medicinal Chemistry","volume":"46 6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76618838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}