Advances in Health Sciences Research最新文献

Multicomponent Crystal of Fenofibric Acid- Saccharin: Characterization and Antihyperlipidemic Effectiveness 非纤维酸糖精的多组分晶体:表征和降血脂效果

Advances in Health Sciences Research Pub Date : 1900-01-01 DOI: 10.2991/ahsr.k.211105.015

S. Umar, Nedita Putri Bandaro, D. Anggraini, Erizal Zaini

{"title":"Multicomponent Crystal of Fenofibric Acid- Saccharin: Characterization and Antihyperlipidemic Effectiveness","authors":"S. Umar, Nedita Putri Bandaro, D. Anggraini, Erizal Zaini","doi":"10.2991/ahsr.k.211105.015","DOIUrl":"https://doi.org/10.2991/ahsr.k.211105.015","url":null,"abstract":"Fenofibric acid is an active form of fenofibrate which has an antihyperlipidemic effect. Fenofibric acid belongs to BCS class II, which has low solubility and high permeability. The aim of this study was to form multicomponent crystal of fenofibric acid and saccharin that can increase the solubility and dissolution rate, as well as impact on its effectiveness. The ratio of the mixture of fenofibric acid and saccharin was determined using two phase diagram. Characterizations were carried out by Differential Scanning Calorimetry (DSC), X-Ray Diffraction (XRD), Fourier Transform Infrared (FTIR), and the evaluations carried out are solubility, dissolution rate and antihyperlipidemic effectiveness. Based on the two phase diagram a mixture of fenofibric acid and saccharin produce eutectic point at 1:1 mole ratio. Multicomponent crystal showed a decrease in melting point with DSC analysis, no new crystalline phase was formed in X-ray diffraction analysis and did not show any chemical interactions in FTIR analysis. Multicomponent crystal showed an increase in the solubility and dissolution rate. The results of the effectiveness of antihyperlipidemic showed that multicomponent crystal was more effective than fenofibric acid.","PeriodicalId":230596,"journal":{"name":"Advances in Health Sciences Research","volume":"41 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120849698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Various Chloride Salt Addition in Mesoporous Material (SBA-15) Synthesis and Potential as Carrier for Dissolution Enhancer 介孔材料(SBA-15)中不同氯盐添加量的合成及其作为溶出促进剂载体的潜力

Advances in Health Sciences Research Pub Date : 1900-01-01 DOI: 10.2991/ahsr.k.211105.050

Uswatul Hasanah, S. Wikarsa, Sukmadjaja Asyarie

引用次数: 1

Need Analysis of Basic Training Model of Forehand and Backhand Groundstroke Technique Based on Actions Method for Boys Aged 8-12 Years Old in Tennis 基于动作法的8-12岁男孩网球正反手落地技术基本训练模式需求分析

Advances in Health Sciences Research Pub Date : 1900-01-01 DOI: 10.2991/ahsr.k.220106.052

N. Ngatman, M. F. Hidayatullah, S. Sugiyanto, S. Purnama

{"title":"Need Analysis of Basic Training Model of Forehand and Backhand Groundstroke Technique Based on Actions Method for Boys Aged 8-12 Years Old in Tennis","authors":"N. Ngatman, M. F. Hidayatullah, S. Sugiyanto, S. Purnama","doi":"10.2991/ahsr.k.220106.052","DOIUrl":"https://doi.org/10.2991/ahsr.k.220106.052","url":null,"abstract":"Forehand and backhand groundstroke is the most dominant technique used in tennis. These two techniques are the first basic techniques that are taught to children when they begin learning to play tennis. However, in fact, forehand and backhand groundstroke is the most difficult techniques for children to learn. The purpose of this study was to analyze the need for a basic forehand and backhand groundstroke training model based on an easy-to-learn action method for children. The method used in this research is descriptive analytic method using qualitative and quantitative approaches. The subjects in this study were coaches from tennis associations/schools who trained 10 children aged 8-12 years in the DIY Province. Questionnaires and structured interviews were used to collect the data. The qualitative data were analyzed by grouping the main ideas of the resource persons, while the quantitative data were analyzed using the percentage technique. This study was successful in identifying the various needs of tennis coaches in order to provide tennis instruction. These needs consist of: 1) the elements required for maximum tennis achievement, 2) the ideal tennis coaching process paradigm, 3) methods to hone ball feeling, ball control, and ball adjustment skills, 4) the need for appropriate training methods that can develop perception, decision, execution, and feedback, and 5) an action method through an open skill process that can develop the ability of perception, decision, execution, and feedback. The Actions method is expected to make teaching basic forehand and backhand groundstroke techniques to boys aged 8 to 12 years easier.","PeriodicalId":230596,"journal":{"name":"Advances in Health Sciences Research","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126159066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of the Medical Record System at the Mother and Child Hospital (RSIA) Puri Bunda Malang City, East Java in 2019 2019年东爪哇省普里本达玛琅市妇幼医院(RSIA)病历系统管理

Advances in Health Sciences Research Pub Date : 1900-01-01 DOI: 10.2991/ahsr.k.220108.030

Ema Novita Deniati, Annisaa Annisaa

引用次数: 1

The Cytotoxic Effect of Ethanolic Extract of Dasun Tunggal and Garlic (Allium sativum) on Raw 264.7 Cells 大孙冬瓜和大蒜醇提物对264.7细胞的细胞毒作用

Advances in Health Sciences Research Pub Date : 1900-01-01 DOI: 10.2991/ahsr.k.211105.005

Irene Puspa Dewi, F. Wahyuni, Y. Aldi, Dachriyanus

引用次数: 0

In Vivo Cytotoxic Activity and Acute Toxicity Test of Ethanol Extract from Voacanga foetida (Blume) Rolfe Leaves 竹叶乙醇提取物的体内细胞毒活性及急性毒性试验

Advances in Health Sciences Research Pub Date : 1900-01-01 DOI: 10.2991/ahsr.k.211105.003

Adriani Susanty, Emrizal, E. Susanti, Alfionita BR Saragih, H. Muchtar, Dachriyanus

引用次数: 1

Learn Pencak Silat Like Write a Book 像写书一样学铅笔

Advances in Health Sciences Research Pub Date : 1900-01-01 DOI: 10.2991/ahsr.k.220106.061

Cerry Kartika Trizkyana, S. Siswantoyo

引用次数: 1

The Relationship Between Religiosity and Smoking Cessation: An Analysis of Indonesian Family Health Survey 2014 宗教信仰与戒烟的关系:2014年印尼家庭健康调查分析

Advances in Health Sciences Research Pub Date : 1900-01-01 DOI: 10.2991/ahsr.k.220108.025

T. D. Tama, Erni Astutik, Nurnaningsih Herya Ulfah

{"title":"The Relationship Between Religiosity and Smoking Cessation: An Analysis of Indonesian Family Health Survey 2014","authors":"T. D. Tama, Erni Astutik, Nurnaningsih Herya Ulfah","doi":"10.2991/ahsr.k.220108.025","DOIUrl":"https://doi.org/10.2991/ahsr.k.220108.025","url":null,"abstract":"Besides having cultural diversity, Indonesia also has diversity in religion. All religion guide their followers to live in goodness and avoid harmful behavior. Smoking is one of harmful behavior that not only affect health but also others aspect in life. In the last five years, one of third population ≥ 15 years old in Indonesia was smoker. The aim of this study was to determine the relationship between religiosity and smoking cessation in Indonesia. A cross-sectional study was conducted by using secondary data from Indonesian Family Life Survey 2014. As many as 10481 respondents were included in analysis. The association between religiosity and smoking cessation was measured by multiple logistic regression. This study found that the smoking cessation rate was 11.4%. The level of religiosity had a significant association with smoking cessation. Very religious people (aOR 1.99; 95% CI 1.31 – 3.02), religious (aOR 1.83; 95% CI 1.23 – 2.72), somewhat religious (aOR 1.33; 95%CI 0.8 – 2.01) had higher odds to quit smoking than not religious. Increasing religious adherence can lead people to adopt better behaviors, including quitting smoking. Using a religious approach in promoting the dangers of smoking could be an effective way.","PeriodicalId":230596,"journal":{"name":"Advances in Health Sciences Research","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116109258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Storage Time on Colonization of Lactic Acid Bacteria in Breast Milk 储存时间对乳酸菌在母乳中定植的影响

Advances in Health Sciences Research Pub Date : 1900-01-01 DOI: 10.2991/ahsr.k.220303.026

Putri Pasalina, Vitri Amran, Hendri Devita

引用次数: 0

The Responses of HIF-1α and HSP70 to Interval Training with Various Intensities in Indonesian Junior Sprinters 印度尼西亚青少年短跑运动员HIF-1α和HSP70对不同强度间歇训练的反应

Advances in Health Sciences Research Pub Date : 1900-01-01 DOI: 10.2991/ahsr.k.220106.021

E. Purnomo, M. Sadikin

{"title":"The Responses of HIF-1α and HSP70 to Interval Training with Various Intensities in Indonesian Junior Sprinters","authors":"E. Purnomo, M. Sadikin","doi":"10.2991/ahsr.k.220106.021","DOIUrl":"https://doi.org/10.2991/ahsr.k.220106.021","url":null,"abstract":"Interval training (IT) is a method of exercise to improve running ability in predetermined distance and time. This study aims to describe physiological responses (hypoxia-inducible factor-1α (HIF-1α) and heat shock proteins 70 (HSP70)) to several IT in male Indonesian junior sprinters. In this experimental study 17 male junior sprinters were allocated into 3 groups based on exercise intensity: low, moderate and high. Measured were height, body weight, 100 m running speed and biochemical parameters (HIF-1α and HSP70), before IT, during IT, and after a 30-minutes break following IT. Data analyses were performed using Kruskal-Wallis and ANOVA tests. HIF-1α concentration increased in high intensity group after IT compared to the condition during IT was performed, while HSP70 concentration mostly increased in moderate and high intensity groups. HSP70 concentrations were lower in all groups, after the 30-minute break, but did not recover to its concentration before IT was performed. HIF-1α and HSP70 production depended on training intensity. Their concentrations did not reach baseline concentrations after 30-minute break. It is suggested that more than 30 minutes of rest are needed to recover after a very intense training session.","PeriodicalId":230596,"journal":{"name":"Advances in Health Sciences Research","volume":"123 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114584570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0