Ashleigh R Tuite, Victoria Ng, Raphael Ximenes, Alan Diener, Ellen Rafferty, Nicholas H Ogden, Matthew Tunis
{"title":"Quantifying the economic gains associated with COVID-19 vaccination in the Canadian population: A cost-benefit analysis.","authors":"Ashleigh R Tuite, Victoria Ng, Raphael Ximenes, Alan Diener, Ellen Rafferty, Nicholas H Ogden, Matthew Tunis","doi":"10.14745/ccdr.v49i06a03","DOIUrl":"10.14745/ccdr.v49i06a03","url":null,"abstract":"<p><strong>Background: </strong>Vaccination has been a key part of Canada's coronavirus disease 2019 (COVID-19) pandemic response. Although the clinical benefits of vaccination are clear, an understanding of the population-level benefits of vaccination relative to the programmatic costs is of value. The objective of this article is to quantify the economic impact of COVID-19 vaccination in the Canadian population between December 2020 and March 2022.</p><p><strong>Methods: </strong>We conducted a model-based cost-benefit analysis of Canada's COVID-19 vaccination program. We used an epidemiological model to estimate the number of COVID-19 symptomatic cases, hospitalizations, post-COVID condition (PCC) cases, and deaths in the presence and absence of vaccination. Median, lower and upper 95% credible interval (95% CrI) outcome values from 100 model simulations were used to estimate the direct and indirect costs of illness, including the value of health. We used a societal perspective and a 1.5% discount rate.</p><p><strong>Results: </strong>We estimated that the costs of the vaccination program were far outweighed by the savings associated with averted infections and associated downstream consequences. Vaccination increased the net benefit by CAD $298.1 billion (95% CrI: 27.2-494.6) compared to the no vaccination counterfactual. The largest benefits were due to averted premature mortality, resulting in an estimated $222.0 billion (95% CrI: 31.2-379.0) benefit.</p><p><strong>Conclusion: </strong>Our model-based economic evaluation provides a retrospective assessment of COVID-19 vaccination during the first 16 months of the program in Canada and suggests that it was welfare-improving, considering the decreased hospitalizations and use of healthcare resources, deaths averted and lower morbidity from conditions such as PCC.</p>","PeriodicalId":23038,"journal":{"name":"Theoretical and Experimental Plant Physiology","volume":"30 1","pages":"263-273"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10911688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83319166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mara de Menezes de Assis Gomes, Luciane do Nascimento Siqueira, T. M. Ferraz, W. P. Rodrigues, F. A. M. M. A. Figueiredo, Fabrício de Oliveira Reis, E. Campostrini
{"title":"Does abscisic acid and xylem sap pH regulate stomatal responses in papaya plants submitted to partial root-zone drying?","authors":"Mara de Menezes de Assis Gomes, Luciane do Nascimento Siqueira, T. M. Ferraz, W. P. Rodrigues, F. A. M. M. A. Figueiredo, Fabrício de Oliveira Reis, E. Campostrini","doi":"10.1007/s40626-023-00275-3","DOIUrl":"https://doi.org/10.1007/s40626-023-00275-3","url":null,"abstract":"","PeriodicalId":23038,"journal":{"name":"Theoretical and Experimental Plant Physiology","volume":"35 1","pages":"185 - 197"},"PeriodicalIF":2.6,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42124645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Clara A. P. da Silva, P. F. Batista, P. E. Menezes-Silva, Leticia F. Sousa, Lucas Loram-Lourenço, Kamila M. B. Alencar, Igor M. P. G. de Abreu, R. D. Alves, E. S. Freire, F. G. Silva, Jéssica Brasau da Silva, F. Farnese
{"title":"With a little help from my friends: inoculation with Bacillus amyloliquefaciens and Trichoderma asperellum alleviates drought and salt stress in soybean","authors":"Maria Clara A. P. da Silva, P. F. Batista, P. E. Menezes-Silva, Leticia F. Sousa, Lucas Loram-Lourenço, Kamila M. B. Alencar, Igor M. P. G. de Abreu, R. D. Alves, E. S. Freire, F. G. Silva, Jéssica Brasau da Silva, F. Farnese","doi":"10.1007/s40626-023-00274-4","DOIUrl":"https://doi.org/10.1007/s40626-023-00274-4","url":null,"abstract":"","PeriodicalId":23038,"journal":{"name":"Theoretical and Experimental Plant Physiology","volume":"35 1","pages":"169 - 183"},"PeriodicalIF":2.6,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43243280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yu. E. Kolupaev, T. Yastreb, N. I. Ryabchun, A. I. Kokorev, V. Kolomatska, A. Dmitriev
{"title":"Redox homeostasis of cereals during acclimation to drought","authors":"Yu. E. Kolupaev, T. Yastreb, N. I. Ryabchun, A. I. Kokorev, V. Kolomatska, A. Dmitriev","doi":"10.1007/s40626-023-00271-7","DOIUrl":"https://doi.org/10.1007/s40626-023-00271-7","url":null,"abstract":"","PeriodicalId":23038,"journal":{"name":"Theoretical and Experimental Plant Physiology","volume":"35 1","pages":"133 - 168"},"PeriodicalIF":2.6,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45513730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcella Siqueira Simões, G. G. Carvalho, S. S. Ferreira, I. Cesarino
{"title":"Toward the identification of class III peroxidases potentially involved in lignification in the model C4 grass Setaria viridis","authors":"Marcella Siqueira Simões, G. G. Carvalho, S. S. Ferreira, I. Cesarino","doi":"10.1007/s40626-023-00273-5","DOIUrl":"https://doi.org/10.1007/s40626-023-00273-5","url":null,"abstract":"","PeriodicalId":23038,"journal":{"name":"Theoretical and Experimental Plant Physiology","volume":"35 1","pages":"111 - 131"},"PeriodicalIF":2.6,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41336803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Theerawitaya, R. Tisarum, Thapanee Samphumphuang, D. Chungloo, H. S. Singh, S. Cha-um
{"title":"Antitranspirant modulates Na+ enrichment and yield in indica rice under salt stress","authors":"C. Theerawitaya, R. Tisarum, Thapanee Samphumphuang, D. Chungloo, H. S. Singh, S. Cha-um","doi":"10.1007/s40626-023-00272-6","DOIUrl":"https://doi.org/10.1007/s40626-023-00272-6","url":null,"abstract":"","PeriodicalId":23038,"journal":{"name":"Theoretical and Experimental Plant Physiology","volume":"35 1","pages":"99 - 110"},"PeriodicalIF":2.6,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47372250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Renan Falcioni, Thaise Moriwaki, Marlon Rodrigues, Karym Mayara de Oliveira, R. H. Furlanetto, Amanda Silveira dos Reis, Glaucio Leboso Alemparte Abrantes dos Santos, Weslei Augusto Mendonça, L. G. Crusiol, João Vitor Ferreira Gonçalves, Marcelo Luiz Chicati, Roney Berti de Oliveira, M. Nanni, W. C. Antunes
{"title":"Nutrient deficiency lowers photochemical and carboxylation efficiency in tobacco","authors":"Renan Falcioni, Thaise Moriwaki, Marlon Rodrigues, Karym Mayara de Oliveira, R. H. Furlanetto, Amanda Silveira dos Reis, Glaucio Leboso Alemparte Abrantes dos Santos, Weslei Augusto Mendonça, L. G. Crusiol, João Vitor Ferreira Gonçalves, Marcelo Luiz Chicati, Roney Berti de Oliveira, M. Nanni, W. C. Antunes","doi":"10.1007/s40626-023-00268-2","DOIUrl":"https://doi.org/10.1007/s40626-023-00268-2","url":null,"abstract":"","PeriodicalId":23038,"journal":{"name":"Theoretical and Experimental Plant Physiology","volume":"35 1","pages":"81 - 97"},"PeriodicalIF":2.6,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47116305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francisco de Almeida Lobo, Renan Previl, M. Gonzalez-Meler, B. L. C. Pereira, L. C. de Moura, C. Ortíz, Glaucio da Cruz Genuncio, G. Vourlitis
{"title":"Is intrinsic water use efficiency independent of leaf-to-air vapor pressure deficit?","authors":"Francisco de Almeida Lobo, Renan Previl, M. Gonzalez-Meler, B. L. C. Pereira, L. C. de Moura, C. Ortíz, Glaucio da Cruz Genuncio, G. Vourlitis","doi":"10.1007/s40626-023-00269-1","DOIUrl":"https://doi.org/10.1007/s40626-023-00269-1","url":null,"abstract":"","PeriodicalId":23038,"journal":{"name":"Theoretical and Experimental Plant Physiology","volume":"35 1","pages":"65 - 80"},"PeriodicalIF":2.6,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47089894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. M. Henschel, Vitória Stefany de Moura, A. Silva, D. Gomes, Sabrina Kelly dos Santos, D. S. Batista, T. J. Dias
{"title":"Can exogenous methyl jasmonate mitigate salt stress in radish plants?","authors":"J. M. Henschel, Vitória Stefany de Moura, A. Silva, D. Gomes, Sabrina Kelly dos Santos, D. S. Batista, T. J. Dias","doi":"10.1007/s40626-023-00270-8","DOIUrl":"https://doi.org/10.1007/s40626-023-00270-8","url":null,"abstract":"","PeriodicalId":23038,"journal":{"name":"Theoretical and Experimental Plant Physiology","volume":"35 1","pages":"51 - 63"},"PeriodicalIF":2.6,"publicationDate":"2023-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49025130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. R. Bordin, Alexandre Vargas Ilha, Patrick Ruam Bredow Cortes, Walas da Silva Oliveira, Lucas Avila Pinheiro, Elizane E. de Moraes, T. G. Grison, M. H. Köhler
{"title":"Molecular modeling of aquaporins and artificial transmembrane channels: a mini-review and perspective for plants","authors":"J. R. Bordin, Alexandre Vargas Ilha, Patrick Ruam Bredow Cortes, Walas da Silva Oliveira, Lucas Avila Pinheiro, Elizane E. de Moraes, T. G. Grison, M. H. Köhler","doi":"10.1007/s40626-023-00284-2","DOIUrl":"https://doi.org/10.1007/s40626-023-00284-2","url":null,"abstract":"","PeriodicalId":23038,"journal":{"name":"Theoretical and Experimental Plant Physiology","volume":"1 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2023-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43965050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}