The West Virginia medical journal最新文献

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COVID-19: West Virginia Essential Workers and the Risks They Face 2019冠状病毒病:西弗吉尼亚州基本工人及其面临的风险
The West Virginia medical journal Pub Date : 2023-06-01 DOI: 10.21885/wvmj.2023.08
Rayan Ihle, MD, Syed Kashif Mahmood, MD
{"title":"COVID-19: West Virginia Essential Workers and the Risks They Face","authors":"Rayan Ihle, MD, Syed Kashif Mahmood, MD","doi":"10.21885/wvmj.2023.08","DOIUrl":"https://doi.org/10.21885/wvmj.2023.08","url":null,"abstract":"Introduction The COVID-19 pandemic resulted in the need for antibody testing to determine the impact of the disease. This study quantifies the COVID-19 infection risk of healthcare workers (HCW) compared to other community essential workers (CEW) through positive COVID-19 antibody rates. Methods This prospective observational study was conducted September through December 2020 in Charleston, West Virginia. A total of 1,081 essential workers were recruited. Blood samples were tested for SARS-CoV-2 IgG antibodies and questionnaires were obtained describing symptom history, exposure, prior testing, and employment. Results COVID-19 antibodies were found in 7.8% of participants. There were no significant differences in terms of gender, living alone or with children, month of lab collection, or working on a COVID-19 unit. Risk factors included having a known exposure (p<0.001), living with someone with COVID-19 (p<0.001), being previously tested (p<0.001), and positive polymerase chain reaction tests (p<0.001). Additional risks were county of residence (p=0.02) and working in healthcare (p=0.004). Discussion Essential workers had a nearly 60% increased risk of COVID-19 compared with the public. HCW had a higher risk than other CEW with rates 1.8 times that of CEW. Living in Kanawha County was a risk factor, but the difference was driven by the HCW population with 12.1% positivity. HCW in a COVID-19 unit had similar positive rates versus non-COVID-19 units. Conclusion This study confirms that healthcare workers had a much higher risk of contracting COVID-19 near Charleston, WV. With these findings, despite the use of safety guidelines and use of personal protective equipment, healthcare workers in Kanawha County had higher positivity rates for SARS-CoV-2 IgG antibodies. Further evaluation of PPE compliance, hand hygiene habits, sharing work cultures, and roles within hospital would be of value.","PeriodicalId":23032,"journal":{"name":"The West Virginia medical journal","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87024811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of COVID-19 Infection on Concurrent Traumatic Insults: An Analysis from the West Virginia Trauma System COVID-19感染对并发创伤性损伤的影响:来自西弗吉尼亚州创伤系统的分析
The West Virginia medical journal Pub Date : 2023-06-01 DOI: 10.21885/wvmj.2023.10
Santiago Lopez, BS, Cristhian Perez Torrico, BS, Connie DeLa'O, MD
{"title":"The Impact of COVID-19 Infection on Concurrent Traumatic Insults: An Analysis from the West Virginia Trauma System","authors":"Santiago Lopez, BS, Cristhian Perez Torrico, BS, Connie DeLa'O, MD","doi":"10.21885/wvmj.2023.10","DOIUrl":"https://doi.org/10.21885/wvmj.2023.10","url":null,"abstract":"Introduction With the onset of the COVID-19 pandemic, elective surgeries were decreased and associated with worsened outcomes. Trauma outcomes have been varied, and rural traumas have not been solely analyzed. This study investigated outcomes related to COVID-19 infection at a rural Level I trauma center in West Virginia (WV). Methods A retrospective analysis of trauma outcomes of patients aged 18 years and older from March 30, 2020, until December 21, 2021, presenting to a Level I trauma center in WV was conducted. Data was collected from the John Michael Moore Trauma Center trauma registry. Mortality, complications, injury characteristics, comorbidities, and demographics were examined. Results Out of 2,118 patients tested for the novel coronavirus, 61 (1.7%) were positive (COV+). There was no significant increase in mortality regarding COVID-19 infection. COV+ patients had an increased length of stay (median 5.2 vs. 3.6, p=0.015) and intubation rates (21.3% vs. 12.5%, p=0.070), but fewer days on a ventilator (median, 2 vs. 3, p=0.012). COV+ patients were more likely to be discharged to rehabilitation centers, skilled nursing facilities, or long-term acute care hospitals (44.3% vs 34.5%), and less often routine or home measures (42.6% vs. 58.7%) (p=0.015). Conclusion This single retrospective study found increased rates of length of stay and intubation rates with no increased rates of mortality or complications in COV+ trauma patients compared to non-COV+ trauma patients. Further research is needed to validate and characterize the impact of COVID-19 for the entirety of the state.","PeriodicalId":23032,"journal":{"name":"The West Virginia medical journal","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88866078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 Pandemic Effects on Seasonal Influenza Patterns in West Virginia COVID-19大流行对西弗吉尼亚州季节性流感模式的影响
The West Virginia medical journal Pub Date : 2023-06-01 DOI: 10.21885/wvmj.2023.09
Ryan Demkowicz, MD, P. R. LaSala, MD, Peter Stoilov, PhD, James Denvir, PhD, Jonathan Moddle, Peter Perrotta, MD
{"title":"COVID-19 Pandemic Effects on Seasonal Influenza Patterns in West Virginia","authors":"Ryan Demkowicz, MD, P. R. LaSala, MD, Peter Stoilov, PhD, James Denvir, PhD, Jonathan Moddle, Peter Perrotta, MD","doi":"10.21885/wvmj.2023.09","DOIUrl":"https://doi.org/10.21885/wvmj.2023.09","url":null,"abstract":"Introduction The COVID-19 pandemic began in West Virginia (WV) in March 2020 at the end of the seasonal increase in influenza virus infections. Diagnostic and surveillance testing for influenza continued throughout the pandemic because these viruses cause similar diseases and the effects of SARS-CoV-2 on seasonal influenza patterns were unpredictable. Methods Positivity rates for SARS-CoV-2 and influenza viruses were studied using test results obtained from samples collected across an academic health system from July 2018 through June 2022. Trends in COVID-19 variants were assessed using data obtained from national and local databases. Data were analyzed to detect differences in and correlations between SARS-CoV-2 and influenza positivity rates. Results Test positivity rates were higher for the 602,109 SARS-CoV-2 tests than the 186,563 influenza tests performed during the study period (13.7% vs. 3.5%, p<0.0001). SARS-CoV-2 test positivity rose and fell with the emergence of SARS-CoV-2 variants of differing infectivity, being highest when the omicron variant predominated. Significant negative correlations between the number of SARS-CoV-2 and influenza positive tests were seen throughout stages of the pandemic. The normally expected influenza season did not occur during winter 2020 through spring 2021, and there were essentially no influenza cases during the delta surge. A more typical pattern of seasonal influenza was observed in late 2021 to early 2022 during the omicron surge. Conclusion There was an inverse correlation between SARS-CoV-2 and influenza test positivity rates observed throughout several COVID-19 surges in WV. The reasons for these correlations are unclear.","PeriodicalId":23032,"journal":{"name":"The West Virginia medical journal","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73850907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent Pneumothorax and a Solitary Pulmonary Nodule: A Case Report of a Rare Sequelae of Histoplasmosis 复发性气胸和孤立性肺结节:罕见的组织浆菌病后遗症1例
The West Virginia medical journal Pub Date : 2022-12-01 DOI: 10.21885/wvmj.2022.24
L. Hamrick, B. Balakrishnan
{"title":"Recurrent Pneumothorax and a Solitary Pulmonary Nodule: A Case Report of a Rare Sequelae of Histoplasmosis","authors":"L. Hamrick, B. Balakrishnan","doi":"10.21885/wvmj.2022.24","DOIUrl":"https://doi.org/10.21885/wvmj.2022.24","url":null,"abstract":"Histoplasmosis is a fungal infection caused by a histoplasma species known to be endemic to the Ohio River valley region. Commonly encountered as a solitary pulmonary nodule, histoplasmosis has both acute and chronic forms. We present a case of a 36-year-old woman with multiple episodes of pneumothorax who was ultimately diagnosed with pulmonary histoplasmosis, demonstrating a complication of chronic pulmonary histoplasmosis, which has not been reported in the medical literature.","PeriodicalId":23032,"journal":{"name":"The West Virginia medical journal","volume":"108 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77629866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editor's Letter: When Race is Included in Medical Manuscripts 编者信:当种族被纳入医学手稿
The West Virginia medical journal Pub Date : 2022-12-01 DOI: 10.21885/wvmj.2022.19
Linda Nield, MD
{"title":"Editor's Letter: When Race is Included in Medical Manuscripts","authors":"Linda Nield, MD","doi":"10.21885/wvmj.2022.19","DOIUrl":"https://doi.org/10.21885/wvmj.2022.19","url":null,"abstract":"","PeriodicalId":23032,"journal":{"name":"The West Virginia medical journal","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85684876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Microcephaly After Multiple Fetal Exposures 多次胎儿暴露后的小头畸形
The West Virginia medical journal Pub Date : 2022-12-01 DOI: 10.21885/wvmj.2022.23
Lesley Cottrell, PhD, Alicia Moise, MD, Carrie Moore, MD, Mark Polak, MD
{"title":"Microcephaly After Multiple Fetal Exposures","authors":"Lesley Cottrell, PhD, Alicia Moise, MD, Carrie Moore, MD, Mark Polak, MD","doi":"10.21885/wvmj.2022.23","DOIUrl":"https://doi.org/10.21885/wvmj.2022.23","url":null,"abstract":"","PeriodicalId":23032,"journal":{"name":"The West Virginia medical journal","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88580471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Message from the President: Engagement, Leadership, Education 总统致辞:参与、领导、教育
The West Virginia medical journal Pub Date : 2022-12-01 DOI: 10.21885/wvmj.2022.20
Lisa Costello, MD, MPH, FAAP
{"title":"Message from the President: Engagement, Leadership, Education","authors":"Lisa Costello, MD, MPH, FAAP","doi":"10.21885/wvmj.2022.20","DOIUrl":"https://doi.org/10.21885/wvmj.2022.20","url":null,"abstract":"","PeriodicalId":23032,"journal":{"name":"The West Virginia medical journal","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91525936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Catatonia Associated with Buprenorphine-Induced Toxic Leukoencephalopathy 与丁丙诺啡诱导的中毒性白质脑病相关的紧张症
The West Virginia medical journal Pub Date : 2022-12-01 DOI: 10.21885/wvmj.2022.22
Danielle DeCicco, MD, PhD, Jessica Thayer, MD, Ziad Dimachkie, MD
{"title":"Catatonia Associated with Buprenorphine-Induced Toxic Leukoencephalopathy","authors":"Danielle DeCicco, MD, PhD, Jessica Thayer, MD, Ziad Dimachkie, MD","doi":"10.21885/wvmj.2022.22","DOIUrl":"https://doi.org/10.21885/wvmj.2022.22","url":null,"abstract":"It is well-known that West Virginia (WV) is one of the states most affected by the opioid epidemic. Recently, WV has implemented a program to expand buprenorphine use as part of a multi-prong approach to treat opioid use disorder accompanied by positive outcomes. However, buprenorphine can be diverted and obtained outside of a medical provider's guidance. Given the prevalence of buprenorphine use in WV, we aim to present original clinical data prompting clinicians to recognize buprenorphine as a potential cause of toxic leukoencephalopathy. We describe the case of a 28-year-old female who presented with catatonia believed to be secondary to buprenorphine, and we discuss the diagnostic challenges and therapeutic management of buprenorphine-induced toxic leukoencephalopathy.","PeriodicalId":23032,"journal":{"name":"The West Virginia medical journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75847549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of Pediatric Celiac Disease in Southern West Virginia 西弗吉尼亚州南部儿童乳糜泻的特点
The West Virginia medical journal Pub Date : 2022-12-01 DOI: 10.21885/wvmj.2022.21
Rahiya Rehman, MD, Anam Bashir, MD, Stephanie Thompson, PhD, Pratikkumar Patel, MD, MPH, FAAP
{"title":"Characteristics of Pediatric Celiac Disease in Southern West Virginia","authors":"Rahiya Rehman, MD, Anam Bashir, MD, Stephanie Thompson, PhD, Pratikkumar Patel, MD, MPH, FAAP","doi":"10.21885/wvmj.2022.21","DOIUrl":"https://doi.org/10.21885/wvmj.2022.21","url":null,"abstract":"Purpose Celiac disease (CD) is a disorder in which gluten ingestion triggers an autoimmune response causing inflammation and damage to the small intestine. With improved awareness and screening availability, prevalence and variation in clinical presentation have subsequently increased. Thus, our study identified the disease characteristics and presentation patterns of pediatric CD in southern West Virginia. Methods We retrospectively reviewed charts for pediatric patients (age <18 years) diagnosed with CD during a 10-year period at a tertiary care hospital. Results A total of 59 patients met inclusion criteria. The mean age of diagnosis was 10.0+4.6 years, with 61% of patients being female. One-third of cases were asymptomatic and diagnosed from screenings of patients with hypothyroidism or type 1 diabetes mellitus. In symptomatic patients (n=40), abdominal pain was the most common presenting symptoms (78%), followed by constipation (30%). Classical symptoms of diarrhea and failure to thrive/unexplained weight loss were less common (n=9). At diagnosis, anti-tissue transglutaminase (tTG) IgA antibodies and deamidated gliadin peptide IgG antibodies were both positive in 88% of cases, and endomysial antibodies were positive in 70% cases. One-year post-diagnosis clinic follow-up rate was 63%. A gluten-free diet improved symptoms and tTG IgA serology levels in all patients with follow-up. Conclusion Our data fills in the gap of the paucity of information available about CD in children from Appalachia. A high index of suspicion is required to screen and diagnose CD as many patients are either asymptomatic or lack classical findings. A gluten-free diet is a highly effective treatment, although follow-up after initial diagnosis remains a challenge.","PeriodicalId":23032,"journal":{"name":"The West Virginia medical journal","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85574949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Message from the President - Physician Leadership and Advocacy 来自总统的信息-医师领导和倡导
The West Virginia medical journal Pub Date : 2022-09-01 DOI: 10.21885/wvmj.2022.14
Lisa M. Costello, MD, MPH, FAAP
{"title":"Message from the President - Physician Leadership and Advocacy","authors":"Lisa M. Costello, MD, MPH, FAAP","doi":"10.21885/wvmj.2022.14","DOIUrl":"https://doi.org/10.21885/wvmj.2022.14","url":null,"abstract":"","PeriodicalId":23032,"journal":{"name":"The West Virginia medical journal","volume":"153 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77505688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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