{"title":"Health of Children Born after Intracytoplasmic Sperm Injections (ICSI)","authors":"S. Sabti, Alastair G. Sutcliffe","doi":"10.1017/9781108887595.010","DOIUrl":"https://doi.org/10.1017/9781108887595.010","url":null,"abstract":"","PeriodicalId":230303,"journal":{"name":"Manual of Intracytoplasmic Sperm Injection in Human Assisted Reproduction","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125548910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In Vitro Fertilization and Micromanipulation","authors":"Jacques Cohen","doi":"10.1017/9781108887595.002","DOIUrl":"https://doi.org/10.1017/9781108887595.002","url":null,"abstract":"Male Factor Infertility: Historical Aspects Before 1980 Not everything in medical science has a clear beginning. The first realization of infertility and putative remedies remain shrouded in contextual history, but likely goes back to the dawn of our species, well before there was a written record. Childlessness was, and is still, considered a burden in some communities. Early feminism and medical enlightenment in the nineteenth century, such as the discovery of the ovum in 1827 by Von Baer [1] and the observation of the mammalian fertilization process in sea urchins by Oskar Hertwig in 1876 and rabbit by Leopold Schenk in 1878 [2], laid the foundations for our understanding of the role of spermatozoa and oocytes in reproduction, although the concept of the infertile man was not deeply explored or reported until the late 1920s [3,4]. Sperm function studies commenced only after the Second World War, with semen analysis becoming a systematic and published diagnostic method using mathematical endpoints in a similar approach to that of blood chemistry laboratories [5–7]; mammalian spermatozoa being successfully cryopreserved by Polge and co-workers in 1949 [8] and later in the human by Bunge and Sherman in 1953 [9]; and the maturation processes which spermatozoa had to undergo after meiosis being described in some detail [10,11]. Since the early 1970s there has been an increase in the development of new assays studying seminal chemistry, male pronuclear formation, membrane fusion, genetics and complex morphology, but despite much progress, many aspects of spermatozoa and the fertilization process remain unexplored [12,13]. Microscopic semen analysis provided medical fertility specialists interested in andrology with tools for diagnosis and possible treatment, and even in the relative absence of a scientific basis and medical literature in the 1930s, some open-minded practitioners taught Obstetrics and Gynecology residents about the reality of male infertility. When Patrick Steptoe was a pre-war registrar at St. George’s Hospital in London, his clinical supervisor in the National Health Service, consultant Mr. Gwillim, explained that as many as one-third of clinical infertility cases could be traced back to male factor [14], but demographic publications were hardly available. It would be another 40 years before a suitable and universal treatment was found in in vitro fertilization (IVF) and particularly once the egg was microsurgically prepared to promote fertilization using fledgling new micromanipulation procedures [15–20]. This culminated in the development of a definitive solution (although not a remedy) for male factor infertility, first successfully applied at the Free University of Brussels in Belgium: the direct injection of a single immobilized spermatozoon into the ooplasm, a procedure the authors described as intra-cytoplasmic sperm injection (ICSI) [21]. This chapter reviews the brief but intense period of the exploration of male factor tr","PeriodicalId":230303,"journal":{"name":"Manual of Intracytoplasmic Sperm Injection in Human Assisted Reproduction","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122128435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Cheung, A. Parrella, P. Xie, Sherina Lawrence, Mounia Haddad, D. Keating, Z. Rosenwaks, G. Palermo
{"title":"Development of ICSI in Human Assisted Reproduction","authors":"S. Cheung, A. Parrella, P. Xie, Sherina Lawrence, Mounia Haddad, D. Keating, Z. Rosenwaks, G. Palermo","doi":"10.1017/9781108887595.003","DOIUrl":"https://doi.org/10.1017/9781108887595.003","url":null,"abstract":"","PeriodicalId":230303,"journal":{"name":"Manual of Intracytoplasmic Sperm Injection in Human Assisted Reproduction","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114869521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Keating, S. Cheung, P. Xie, June Wang, Z. Rosenwaks, G. Palermo
{"title":"Current ICSI Applications and Clinical Outcomes","authors":"D. Keating, S. Cheung, P. Xie, June Wang, Z. Rosenwaks, G. Palermo","doi":"10.1017/9781108887595.004","DOIUrl":"https://doi.org/10.1017/9781108887595.004","url":null,"abstract":"","PeriodicalId":230303,"journal":{"name":"Manual of Intracytoplasmic Sperm Injection in Human Assisted Reproduction","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128816031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Plate Section (PDF Only)","authors":"","doi":"10.1017/9781108887595.019","DOIUrl":"https://doi.org/10.1017/9781108887595.019","url":null,"abstract":"","PeriodicalId":230303,"journal":{"name":"Manual of Intracytoplasmic Sperm Injection in Human Assisted Reproduction","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131395529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Examining the Safety of ICSI Using Animal Models","authors":"L. Hewitson","doi":"10.1017/9781108887595.011","DOIUrl":"https://doi.org/10.1017/9781108887595.011","url":null,"abstract":"","PeriodicalId":230303,"journal":{"name":"Manual of Intracytoplasmic Sperm Injection in Human Assisted Reproduction","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117074007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cellular and Molecular Events after ICSI in Clinically Relevant Animal Models","authors":"L. Hamilton, R. Oko, P. Sutovsky","doi":"10.1017/9781108887595.012","DOIUrl":"https://doi.org/10.1017/9781108887595.012","url":null,"abstract":"","PeriodicalId":230303,"journal":{"name":"Manual of Intracytoplasmic Sperm Injection in Human Assisted Reproduction","volume":"146 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121231331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Automation Techniques and Systems for ICSI","authors":"C. Dai, Zhuoran Zhang, Guanqiao Shan, Yu Sun","doi":"10.1017/9781108887595.014","DOIUrl":"https://doi.org/10.1017/9781108887595.014","url":null,"abstract":"","PeriodicalId":230303,"journal":{"name":"Manual of Intracytoplasmic Sperm Injection in Human Assisted Reproduction","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114201422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Index","authors":"","doi":"10.1017/9781108887595.018","DOIUrl":"https://doi.org/10.1017/9781108887595.018","url":null,"abstract":"","PeriodicalId":230303,"journal":{"name":"Manual of Intracytoplasmic Sperm Injection in Human Assisted Reproduction","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133760824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Germline Nuclear Transfer Technology to Overcome Mitochondrial Diseases and Female Infertility","authors":"M. Tang, A. Boel, Paul Couke, B. Heindryckx","doi":"10.1017/9781108887595.015","DOIUrl":"https://doi.org/10.1017/9781108887595.015","url":null,"abstract":"","PeriodicalId":230303,"journal":{"name":"Manual of Intracytoplasmic Sperm Injection in Human Assisted Reproduction","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116010585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}