发布求助
文献互助 智能选刊 最新文献

The Open Organic Chemistry Journal最新文献

筛选
英文 中文
Steric and Electronic Effects of Benzoferrocenyl Phosphine Ligands on Palladium-Catalyzed Allylic Alkylation and Suzuki Coupling Reactions 苯并二茂基膦配体对钯催化烯丙基烷基化和铃木偶联反应的空间和电子效应
The Open Organic Chemistry Journal Pub Date : 2008-03-10 DOI: 10.2174/1874095200801020001
M. Thimmaiah, R. Luck, Shiyue Fang
{"title":"Steric and Electronic Effects of Benzoferrocenyl Phosphine Ligands on Palladium-Catalyzed Allylic Alkylation and Suzuki Coupling Reactions","authors":"M. Thimmaiah, R. Luck, Shiyue Fang","doi":"10.2174/1874095200801020001","DOIUrl":"https://doi.org/10.2174/1874095200801020001","url":null,"abstract":"Five benzoferrocenyl phosphine ligands with the phosphorus atom attached to the 5-position of the benzofer- rocene and some ligand-Mo(CO)5 complexes were prepared and fully characterized; the structure of one ligand was con- firmed by X-ray crystallography. These ligands were applied in palladium-catalyzed allylic alkylation and Suzuki cou- pling of chlorobenzene with phenylboronic acid. Results were compared with those reported previously using ligands hav- ing the phosphorus atom attached to the 4-position of benzoferrocene. This structural modification resulted in an increase of activity of the ligands in allylic alkylation reaction but a decrease of activity in Suzuki coupling reactions. The underly- ing reasons are analyzed with the help of X-ray single crystal determined structures and CO stretching frequencies in the IR spectra of complexes between the ligands and Mo(CO)5.","PeriodicalId":23020,"journal":{"name":"The Open Organic Chemistry Journal","volume":"74 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2008-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90051530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Microwave Synthesis of Arylmethyl Substituted Pyrazoles 芳基甲基取代吡唑的微波合成
The Open Organic Chemistry Journal Pub Date : 2008-03-10 DOI: 10.2174/1874095200801020010
C. Escolástico, M. Blanco, R. Claramunt, D. Sanz, J. Elguero
{"title":"Microwave Synthesis of Arylmethyl Substituted Pyrazoles","authors":"C. Escolástico, M. Blanco, R. Claramunt, D. Sanz, J. Elguero","doi":"10.2174/1874095200801020010","DOIUrl":"https://doi.org/10.2174/1874095200801020010","url":null,"abstract":"The synthesis under MW irradiation without solvent of 19 pyrazoles, of which only 8 were known, is described. They bear C-methyl groups and trityl, diphenylmethyl and benzyl groups at positions 1 and 4 of the pyrazole ring. In the reaction between pyrazole and trityl bromide an unexpected reaction occurred and 4-(9-phenyl-9H-fluoren-9-yl)-1H- pyrazole (7) was isolated.","PeriodicalId":23020,"journal":{"name":"The Open Organic Chemistry Journal","volume":"31 1","pages":"10-16"},"PeriodicalIF":0.0,"publicationDate":"2008-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79060763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A convenient reduction of α-amino acids to 1,2-amino alcohols with retention of optical purity 方便α-氨基酸还原为1,2-氨基醇，保留光学纯度
The Open Organic Chemistry Journal Pub Date : 2008-01-01 DOI: 10.2174/1874095200802010107
Sun‐Hee Hwang, M. Blaskovich, H. Kim
{"title":"A convenient reduction of α-amino acids to 1,2-amino alcohols with retention of optical purity","authors":"Sun‐Hee Hwang, M. Blaskovich, H. Kim","doi":"10.2174/1874095200802010107","DOIUrl":"https://doi.org/10.2174/1874095200802010107","url":null,"abstract":"A convenient one-pot synthesis of 1,2-amino alcohols from -amino acids with retention of optical purity by use of 1,1’-carbonyldiimidazole and sodium borohydride is described.","PeriodicalId":23020,"journal":{"name":"The Open Organic Chemistry Journal","volume":"4 1","pages":"107-109"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83652752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Molecular Descriptors for Natural Diamondoid Hydrocarbons and Quantitative Structure-Property Relationships for Their Chromatographic Data 天然金刚石类化合物的分子描述符及其色谱数据的定量构效关系
The Open Organic Chemistry Journal Pub Date : 2007-10-24 DOI: 10.2174/1874095200701010013
A. Balaban, D. Klein, J. Dahl, R. Carlson
{"title":"Molecular Descriptors for Natural Diamondoid Hydrocarbons and Quantitative Structure-Property Relationships for Their Chromatographic Data","authors":"A. Balaban, D. Klein, J. Dahl, R. Carlson","doi":"10.2174/1874095200701010013","DOIUrl":"https://doi.org/10.2174/1874095200701010013","url":null,"abstract":"Diamond hydrocarbons (or diamondoids) are hydrocarbons that have a carbon skeleton superimposable on the diamond lattice and contain one or more adamantane units. Recently it was found that many higher diamondoids (contain- ing four to eleven adamantane units) are present in petroleum and can be isolated by a series of methods that include HPLC and GC techniques. We develop QSPR equations using molecular descriptors derived from the topology and geo- metry of diamondoids, by means of dualist graphs consisting of vertices placed at the centers of adamantane cells forming the diamondoid, and of edges connecting vertices centered in adamantane cells sharing faces. From distance (or distance- distance) matrices encoding the topology and geometry of diamondoids one can obtain distance-sums, distance-distance sums, or eigenvectors as molecular descriptors characterizing the diamondoids. These descriptors afford satisfactory cor- relations with GC and HPLC retention data, and may also facilitate the identification of diamondoid isomers.","PeriodicalId":23020,"journal":{"name":"The Open Organic Chemistry Journal","volume":"96 1","pages":"13-31"},"PeriodicalIF":0.0,"publicationDate":"2007-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91276026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Convenient Synthesis of Highly Functionalized, 3,4-Disubstituted Indole Building Blocks 高功能化3,4-二取代吲哚构建块的便捷合成
The Open Organic Chemistry Journal Pub Date : 2007-09-28 DOI: 10.2174/1874095200701010001
Sonia R. Miranda, P. López‐Alvarado, C. Avendaño, J. Menéndez
{"title":"Convenient Synthesis of Highly Functionalized, 3,4-Disubstituted Indole Building Blocks","authors":"Sonia R. Miranda, P. López‐Alvarado, C. Avendaño, J. Menéndez","doi":"10.2174/1874095200701010001","DOIUrl":"https://doi.org/10.2174/1874095200701010001","url":null,"abstract":"Several 3,4-disubstituted indole building blocks were synthesized, containing a one-carbon functional group at C-4 and a three-carbon chain bearing at least one  functional group. A C-4 functionalized indole derivative was prepared by application of the Leimgruber-Batcho reaction. Several three-carbon chains were subsequently installed at the indole C-3 position. In the first strategy employed, a Mannich reaction was followed by the creation of a C-C bond by phosphine-induced generation of a 3-methyleneindolenine species, which was trapped by diethyl malonate. Alternatively, a Vilsmeier formylation at C-3 was followed by Knoevenagel or Wittig reactions or by treatment with ethyl diazoacetate in the presence of a Lewis acid. Direct introduction of the three-carbon chain at C-3 using a Lewis acid-catalyzed Michael reaction was also achieved. Further functionalization of the benzylic position attached to C-4 by attachment of a nitro group was carried out, but preparation of a tricyclic welwistatin fragment by intramolecular nitroalkane acylation or in- tramolecular Henry reactions was not possible.","PeriodicalId":23020,"journal":{"name":"The Open Organic Chemistry Journal","volume":"5 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2007-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74961107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
首页 上一页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信