Global NeurologyPub Date : 2020-10-17DOI: 10.36879/gon.20.000109
{"title":"Hypophosphatemic Osteomalacia associated with Neurofibromatosis Type-1: A case report and literature review","authors":"","doi":"10.36879/gon.20.000109","DOIUrl":"https://doi.org/10.36879/gon.20.000109","url":null,"abstract":"Introduction: Skeleton abnormalities are not uncommon in neurofibromatosis type-1 (NF1), which usually manifest as congenital\u0000malformations, such as scoliosis and sphenoid wing dysplasia. However, very rare cases of NF1 have been associated with\u0000hypophosphatemic osteomalacia (HO), which is characterized with later onset in adulthood, severe hypophosphatemia and disorder\u0000of the mineralization of organic bone matrix.\u0000Patient concerns: Here we reported a rare case of a 29-year-old woman presented with weakness and pain in lower limbs for 18\u0000months and aggravated for half a year. On physical examination, her lower limbs’ myodynamia reduced and tenderness in multiple\u0000bone areas was detected. Light brown patches and scattered nodules could be seen on her skin, and a soft subcutaneous mass was\u0000found in the low back. Laboratory evaluation showed hypophosphatemia. Bone ECT suggested multiple abnormal bone metabolism\u0000and MRI scan of lumbosacral spine revealed numerous fractures. Neuroimaging indicated the neurofibromas, and then the biopsy of\u0000the subcutaneous lump confirmed neurofibromatosis.\u0000Diagnosis: HO associated with NF1 was diagnosed, based on the presence of café-au-lait spots and the results of bone ECT scan and\u0000biopsy.\u0000Interventions: The patient was treated with oral calcitriol, calcium carbonate d3 and phosphorus, as well as intramuscular\u0000carbocalcitonin.\u0000Outcomes: During hospitalization, her serum phosphorus level increased and symptoms improved.\u0000Conclusion: The case reported here calls attention to that when NF1 patients manifested with weakness and neurology diseases have\u0000been excluded, HO should be taken into consideration.","PeriodicalId":230111,"journal":{"name":"Global Neurology","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126992115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global NeurologyPub Date : 2020-08-31DOI: 10.36879/gon.20.000107
{"title":"Stabilizing Effect of Yawning on Nasal Cycle","authors":"","doi":"10.36879/gon.20.000107","DOIUrl":"https://doi.org/10.36879/gon.20.000107","url":null,"abstract":"The dominant passability of the left or right nostril in terms of nasal air resistance can be classified into 4 main modes. In the first mode, both\u0000nostrils are closed and have equal and low air passability. In the second mode, the passability of the right nostril is higher than the left. In the\u0000third mode, the passability of the left nostril is higher than the right. In the fourth mode, both nostrils are open and passability of nostrils is equal\u0000and high. The first and fourth modes are unstable (with duration- minutes). The second and third modes are stable (with duration-hours). Author\u0000presents a yawning as physiological reflex leading to transition from unstable to stable modes.","PeriodicalId":230111,"journal":{"name":"Global Neurology","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115917764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global NeurologyPub Date : 2020-08-27DOI: 10.36879/gon.20.000110
{"title":"Benefits and Circumspections of Cell-Based Therapy of Stroke","authors":"","doi":"10.36879/gon.20.000110","DOIUrl":"https://doi.org/10.36879/gon.20.000110","url":null,"abstract":"","PeriodicalId":230111,"journal":{"name":"Global Neurology","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131637891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global NeurologyPub Date : 2020-08-27DOI: 10.36879/gon.20.000108
{"title":"Marker structures in the liquor of patients with destructive processes in brain tissues","authors":"","doi":"10.36879/gon.20.000108","DOIUrl":"https://doi.org/10.36879/gon.20.000108","url":null,"abstract":"The paper presents the results of studies the solid phase structures of liquor 140 patients’ with various types of destructive brain diseases (74 - neurosyphilis, 26 - bacterial meningitis, 7 - aneurysms, 9 - malignant tumors, 24 - discogenic radiculitis). The transfer of liquor into the solid phase was carried out by the method of marginal dehydration of biological fluids. This method allows to visualize the structure of metabolites of the liquid phase of liquor. The results of the study showed presence in the patients’ liquor marker structures, which could be used to clarify the diagnosis.","PeriodicalId":230111,"journal":{"name":"Global Neurology","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117085482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global NeurologyPub Date : 2020-08-26DOI: 10.36879/gon.20.000106
{"title":"Coronavirus COVID-19 pandemic and its effect on CRPS: An issue to be revisited","authors":"","doi":"10.36879/gon.20.000106","DOIUrl":"https://doi.org/10.36879/gon.20.000106","url":null,"abstract":"","PeriodicalId":230111,"journal":{"name":"Global Neurology","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121163832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global NeurologyPub Date : 2020-02-28DOI: 10.36879/gon.20.000105
{"title":"Neurosurgical procedures in central nervous system vasculitis","authors":"","doi":"10.36879/gon.20.000105","DOIUrl":"https://doi.org/10.36879/gon.20.000105","url":null,"abstract":"","PeriodicalId":230111,"journal":{"name":"Global Neurology","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128650667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global NeurologyPub Date : 2020-02-15DOI: 10.36879/gon.20.000104
{"title":"Ratio of naturally retained 15N to13C in rat brain regions as a unique marker for brain function","authors":"","doi":"10.36879/gon.20.000104","DOIUrl":"https://doi.org/10.36879/gon.20.000104","url":null,"abstract":"","PeriodicalId":230111,"journal":{"name":"Global Neurology","volume":"113 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123384205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global NeurologyPub Date : 2020-01-10DOI: 10.36879/gon.20.000102
{"title":"Aging and Health: A New Relationship","authors":"","doi":"10.36879/gon.20.000102","DOIUrl":"https://doi.org/10.36879/gon.20.000102","url":null,"abstract":"Old age is not of itself a pure neurological ‘problem’, pathology or statement of need. ‘Older people’ or an ‘aging population’ are not a homogeneous\u0000group and categorisation as a distinct service user group is, arguably, contentious. Furthermore, since the advent of personalisation in the UK for,\u0000conceptualizing support by user groups is considered by many as obsolete. People do not receive health services by virtue of being ‘older’. Rather\u0000they are in need of a service - for example, because of ill health, physical impairment, mental health difficulties, addiction or offending. This article\u0000will enable us to consider the implications of the re-figuring of the relationship between the state, older people and health professions and social\u0000work. This constructs an ambiguous place for older people: they feature either as a resource - captured in the idea of the ‘active citizen’, as affluent\u0000consumers, volunteers or providers of childcare- or as a problem in the context of poverty, vulnerability and risk.","PeriodicalId":230111,"journal":{"name":"Global Neurology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115304762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}