M.C. Teucci, G. Braccini, C. Carpeggiani, C. Marchesi
{"title":"An application of self-organising maps for a knowledge base for use in cardiac domain","authors":"M.C. Teucci, G. Braccini, C. Carpeggiani, C. Marchesi","doi":"10.1109/CIC.1997.648013","DOIUrl":"https://doi.org/10.1109/CIC.1997.648013","url":null,"abstract":"The conception, project realisation and updating of hospital information systems (HISs) rely on specific standardisation procedures. Particularly important is the momentum that technology is giving to the production of computer-assisted clinical documentation. Developing such a task, which includes issues like specific diagnostic reports as well as a total clinical record, requires making explicit the syntactic and semantic relationships among the data that describe the patient's health. Our study tackles the realisation of a knowledge-based clinical record designed as a combination of modules depending on a set of main medical concepts. We have heuristically defined the knowledge base's content, which has a frame-based structure, through the self-organising map (SOM) technique. We have used the SOM approach for its intrinsic capability of grouping the words of a text according to the semantic categorisations of the natural language. A set of 30 reports, referring to patients afflicted with cardiac diseases and written in the Italian language, gives us the experimental setting that we have used to train the SOM and to obtain the knowledge base. The lists of words which activate the different nodes of the SOM are assumed as frames of the required knowledge base. Performance evaluation shows that this method gives us a representation of the medical knowledge that is efficient for producing meaningful clinical sentences. Moreover, this approach is of general interest: in fact, it works independently of the language used for writing clinical documents.","PeriodicalId":228649,"journal":{"name":"Computers in Cardiology 1997","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121949578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of hyperpolarizing pulses on a cardiac pacemaker cell","authors":"S. Demir, J. Clark, W. Giles","doi":"10.1109/CIC.1997.648150","DOIUrl":"https://doi.org/10.1109/CIC.1997.648150","url":null,"abstract":"The authors' mathematical model of a rabbit sinoatrial node (SAN) cell (see S. Demir et al., Amer. J. Physiol., vol. 266, p. C832-52, 1994) was studied to explain the phase-sensitive response of this pacemaker cell to single and periodic pulses of hyperpolarizing electrical current. The resulting simulations were presented in phase response curves (PRCs) for the single pulse and in entrainment curves (ECs) for the periodically applied pulses. These graphical representations provided quantitative description of the phase-sensitivity behavior of the SAN cell in rabbit. The authors' computations showed that the characteristics of the phase-sensitive effects are dependent upon the intensity of the stimulus applied. Current-voltage (IV) analysis concluded that the action potential threshold determined by I/sub Ca,L/ was not affected by electrical perturbations. The changes in I/sub Na,Ca/, I/sub f/, I/sub Na/ and I/sub Ca,T/ currents during diastole determine the rate of diastolic depolarization which results in delaying or advancing the following action potential after a stimulus is applied.","PeriodicalId":228649,"journal":{"name":"Computers in Cardiology 1997","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132110479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Ferdeghini, M.A. Morales, M. Piacenti, T. Cerrai, A. Distante, Q. Maggiore
{"title":"Effects of signal compression on quantitative assessment of myocardial structure in digitally stored 2D echocardiographic images","authors":"E. Ferdeghini, M.A. Morales, M. Piacenti, T. Cerrai, A. Distante, Q. Maggiore","doi":"10.1109/CIC.1997.647862","DOIUrl":"https://doi.org/10.1109/CIC.1997.647862","url":null,"abstract":"JPEG compression algorithms produce little degradation of echocardiographic images even at high compression rates. The aim of this study was to assess the effects of different compression levels on the quantitative tonal and textural properties of myocardial structure provided by first and second order statistical algorithms on digitally stored echocardiographic images. JPEG algorithms did not induce significant derangements of quantitative parameters up to high compression rates, suggesting its utilization for digital storage of echocardiographic images to be used also for tissue characterization.","PeriodicalId":228649,"journal":{"name":"Computers in Cardiology 1997","volume":"500 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132235432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A database for evaluation of algorithms for measurement of QT and other waveform intervals in the ECG","authors":"P. Laguna, R. G. Mark, A. Goldberg, George Moody","doi":"10.1109/CIC.1997.648140","DOIUrl":"https://doi.org/10.1109/CIC.1997.648140","url":null,"abstract":"Presents a QT database designed for evaluation of algorithms that detect waveform boundaries in the ECG. The database consists of 105 fifteen-minute excerpts of two-channel ECG Holter recordings, chosen to include a broad variety of QRS and ST-T morphologies. Waveform boundaries for a subset of beats in these recordings have been manually determined by expert annotators using an interactive graphic display to view both signals simultaneously and to insert the annotations. Examples of each morphology were included in this subset of annotated beats; at least 30 beats in each record, 3622 beats in all, were manually annotated in the database. In 11 records, two independent sets of annotations have been included, to allow inter-observer variability studies. The QT Database is available on a CD-ROM in the format previously used for the MIT-BIH Arrhythmia Database and the European ST-T Database, from which some of the recordings in the QT Database have been obtained.","PeriodicalId":228649,"journal":{"name":"Computers in Cardiology 1997","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134071598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Karlsson, J. Brandberg, B. Wranne, P. Ask, D. Loyd
{"title":"Computer simulation for improved assessment of mitral regurgitation","authors":"M. Karlsson, J. Brandberg, B. Wranne, P. Ask, D. Loyd","doi":"10.1109/CIC.1997.647857","DOIUrl":"https://doi.org/10.1109/CIC.1997.647857","url":null,"abstract":"Since valvular regurgitation is one of the most common malfunctions of the heart the quantification of valvular regurgitation by means of non-invasive methods is desired. However existing methods for quantitative assessment is far from perfect. The aim of this paper is to study the proximal velocity field for non-stationary flow and non-planar geometries by computer simulation, which were performed using the FIDAP package to numerically solve the governing equations. A plexiglass in-vitro model similar to the computer model was used for comparison and the same results were obtained. The authors have found that it is possible to refine the PISA method and standardize flow calculations. Further improvements will hopefully create a tool for the echocardiographer that will facilitate evaluation and clinical applicability of the PISA approach.","PeriodicalId":228649,"journal":{"name":"Computers in Cardiology 1997","volume":"123 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134378336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DFT changes in a RV active can (AC) defibrillator due to AC position variations and smaller AC size are reduced by adding a subcutaneous coil electrode","authors":"K. Smits, M. Malík, F. Lindemans","doi":"10.1109/CIC.1997.647838","DOIUrl":"https://doi.org/10.1109/CIC.1997.647838","url":null,"abstract":"A finite difference computer model was used to simulate defibrillation threshold (DFT) and impedance for an Active Can (AC) defibrillator with a 5 cm long right ventricular (RV) electrode. The effects of adding a single subcutaneous (SQ) 25 cm coil electrode to AC were calculated. The efficiency of a configuration was based on the 90 percentile of myocardial current density. Effects of natural variations simulated by variations of RV electrode positions. Clinical results from RV-AC systems (DFT=13J, Z=50.4 /spl Omega/) were used to derive model constants for calculation of DFT. In a factorial experiment DFT, impedance and percentage AC current were calculated for 15 sub-pectoral AC, 12 RV; and 6 SQ positions, resulting in a total of 1260 combinations. Reduction of projected AC size from 37 to 22 and 13 cm/sup 2/, combined for all positions of RV and AC without SQ, resulted in a DFT increase from 13.0/spl plusmn/4.6 to 14.7/spl plusmn/5.3 and 16.5/spl plusmn/5.8 J, and a shock impedance rise from 50.4/spl plusmn/1.5 to 59.0/spl plusmn/2.0 and 68.4/spl plusmn/1.7 /spl Omega/, respectively. Adding a single SQ at 9 different positions, resulted in the following DFT and impedance values: 6.8/spl plusmn/1.9, 6.5/spl plusmn/1.7 and 6.4/spl plusmn/1.5 J; 43.1/spl plusmn/2.5, 46.5/spl plusmn/2.4 and 49.3/spl plusmn/2.4 /spl Omega/, for AC sizes of 37, 22, and 13 cm/sup 2/, respectively. For 5 different AC positions, the DFT without SQ ranged from 10.7/spl plusmn/2.8 J in the most lateral AC positions to 32.1/spl plusmn/10.7 J in the most mid line AC position, and with one SQ combined at 9 positions from 5.8/spl plusmn/1.3 J to 8.4/spl plusmn/2.2 J respectively. Thus addition of one 25 cm SQ to AC of an RV-AC defibrillation system abolishes DFT rise due to AC size reduction and achieves the largest DFT reduction for the most unfavorable AC position.","PeriodicalId":228649,"journal":{"name":"Computers in Cardiology 1997","volume":"41 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132576846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of information redundancy in ECG signals","authors":"B. Açar, L. Ozcakir, H. Koymen","doi":"10.1109/CIC.1997.648153","DOIUrl":"https://doi.org/10.1109/CIC.1997.648153","url":null,"abstract":"In this paper, the morphological information redundancy in standard 12 lead ECG channels is studied. Study is based on decomposing the ECG channels into orthogonal channels by an SVD based algorithm and then reconstructing them. Then 7 of 8 independently recorded ECG channels are decomposed and the missing channel is reconstructed from these orthogonal channels. Thus the unique morphological information content of each ECG channel is assessed through the loss of clinical information in the reconstructed signal. A comparison of the clinical parameters measured from the reconstructed and original ECG is reported.","PeriodicalId":228649,"journal":{"name":"Computers in Cardiology 1997","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133183392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"System identification of atrial activation during chronic atrial fibrillation in man","authors":"Rolf Johansson, M. Holm, S. Olsson, J. Brandt","doi":"10.1109/CIC.1997.647901","DOIUrl":"https://doi.org/10.1109/CIC.1997.647901","url":null,"abstract":"To further clarify the mechanisms maintaining chronic atrial fibrillation (CAF), a method for system identification of activation patterns of the atria was developed. Data were obtained as repeated recordings of 8 s duration, each of 56 atrial bipolar electrograms, simultaneously acquired during open-heart surgery at multiple sites in the right atrial free wall in 12 patients with stable sinus rhythm (SR) and during artificial pacing and 16 patients with chronic atrial fibrillation (AF). Realization theory was applied to fit and reproduce the multivariate electrograms corresponding to individual beats during SR and type I activations during AF, respectively-in all cases and for all subjects tested with good accuracy. The local electrogram was a predictable signal in all cases tested and the proposed method may be used for further investigations concerning the deterministic and predictive nature of atrial activation during atrial fibrillation.","PeriodicalId":228649,"journal":{"name":"Computers in Cardiology 1997","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127395260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Faber, C. Cooke, R. Folks, J. Vansant, J. Klein, E.V. Garcia
{"title":"An integrated processing program for analysis of left ventricular function and perfusion","authors":"T. Faber, C. Cooke, R. Folks, J. Vansant, J. Klein, E.V. Garcia","doi":"10.1109/CIC.1997.648146","DOIUrl":"https://doi.org/10.1109/CIC.1997.648146","url":null,"abstract":"A processing program for analysis of left ventricular perfusion, anatomy, and function from single photon emission computed tomographic perfusion images is presented. This program combines a well-known and validated perfusion quantification approach with a left ventricular surface modeler which enables computation of local and global functional parameters. Thus, perfusion and function can be associated and compared. The results can be displayed in two or three dimensions, using slice displays, polar plots, or surface-shaded 3-D graphics. Finally, the abilities to align a 3-D coronary artery tree with the 3-D left ventricular epicardial surface and display the unification results have been provided, to allow for comparison between coronary anatomy and left ventricular structure and function. Each portion of the analysis package has been separately validated.","PeriodicalId":228649,"journal":{"name":"Computers in Cardiology 1997","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129385282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Frederiks, C. A. Swenne, B. J. Tenvoorde, N. Honzikova, J.V. Levert, A. Maan, M. Schalij, A. Bruschke
{"title":"Non-baroreflex mediated heart rate variability causes overestimation of baroreflex sensitivity","authors":"J. Frederiks, C. A. Swenne, B. J. Tenvoorde, N. Honzikova, J.V. Levert, A. Maan, M. Schalij, A. Bruschke","doi":"10.1109/CIC.1997.647865","DOIUrl":"https://doi.org/10.1109/CIC.1997.647865","url":null,"abstract":"Spectral assessment of baroreflex sensitivity (BRS) is hampered by non-baroreflex mediated heart rate variability (HRV), which adds to the baroreflex mediated HRV. Relating HRV (baroreflex output) to blood pressure variability (BPV, baroreflex input) may therefore yield BRS values that are too large. The authors propose to overcome this problem by computing BRS in the Mayer waves (0.05-0.15 Hz), while keeping the non-baroreflex mediated HRV in the high frequency band by 15/min (0.25 Hz) metronome breathing.","PeriodicalId":228649,"journal":{"name":"Computers in Cardiology 1997","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129828566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}