The Journal of Phytopharmacology最新文献

{"title":"At glance to the plants having anti-inflammatory activity: A review","authors":"Jankhana Baraiya, B. Chauhan, Zuli Shingala","doi":"10.31254/phyto.2022.11311","DOIUrl":"https://doi.org/10.31254/phyto.2022.11311","url":null,"abstract":"From time immemorial man is dependent on plants. The human body has a natural affinity to plants and their products, which are easily absorbed as well as healthier. Medicinal plants are used in treatment of almost all disease. Plants are vast source of active biological compound for new drugs which are safer as well as cost effective. Inflammation is biological response of the human immune system that can be triggered by a variety of factors like damaged cells, toxic compounds, and pathogens. Conventional drugs used for treatment of inflammation has so many disadvantages thus people looking forward safer and effective drug. Various plants are traditionally used in treatment of inflammatory conditions. This review includes some traditionally used herbal plants as an anti-inflammatory drug.","PeriodicalId":22851,"journal":{"name":"The Journal of Phytopharmacology","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90877702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemical screening and effects of aqueous extract of Acalypha wilkesiana Müll. Arg on isolated toad heart","authors":"Wensleslace Landry Mve Mendame, Boris Achille Eyi Mintsa, Alban-Michel Nguema Nguema, A. B. Pambo-Pambo, Ibrahim","doi":"10.31254/phyto.2022.11305","DOIUrl":"https://doi.org/10.31254/phyto.2022.11305","url":null,"abstract":"Medicinal plants are real sources of bioactive molecules. The objective of the present study was to assess the effects of aqueous extract of Acalypha wilkesiana (ALWILEXT) on toad heart. Phytochemical screening of the aqueous extract revealed the presence of bioactives, namely: coumarins, flavones, polyphenols, alkaloids, tannins, terpenes and saponosides. The results obtained show that ALWILEXT, at concentrations ranging from 5.10-5 to 5.10-5g / ml, causes negative inotropic and chronotropic effects on the isolated toad heart, similar to those of acetylcholine although less marked. These effects suggest the presence of adrenomimetics in the aqueous extract. The aqueous extract of Acalypha wilkesiana is said to contain concomitantly adrenomimetics which would justify its use in the treatment of hypertension.","PeriodicalId":22851,"journal":{"name":"The Journal of Phytopharmacology","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79843432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coccinia indica: A Comprehensive Review of Pharmacology, Therapeutic Applications, Nutritional Potentials, and Future Prospects","authors":"R. Padma, V. G.","doi":"10.31254/phyto.2022.11313","DOIUrl":"https://doi.org/10.31254/phyto.2022.11313","url":null,"abstract":"The pharmacognosy, phytochemistry, nutritional value, and ethnopharmacological activity of Coccinia indica (C. indica) are discussed in this review. Many patented compositions generated from C. indica are now widely available around the world. This has resulted in a rise in research on the phytochemical elements of C. indica as well as ethnopharmacological activities. This belongs to the Cucurbitaceae family. Indigenous peoples used several portions of the plant for food and medicine. When the fruit of C. indica is green in colour, it is used as a vegetable, and when it ripens into a beautiful scarlet hue, it is eaten fresh. C. indica's young leaves and branch tips are frequently utilised in traditional medical systems in Asia, including Ayurvedic, Siddha, and Unani. Traditionally, different parts of this plant used in folk medicine for many purposes, such as anti-diabetic, antimicrobial, anti-inflammatory, antioxidant, antimalarial, antidyslipidemic, anticancer, analgesic, antipyretic, antitussive, antinociceptive, hepatoprotective, ant obesity, and neuroprotective function. Many traditional medicines are made from medicinal plants, minerals, and organic materials, which is why this review is focused on that particular plant. The utilisation of numerous medicinal plants from the traditional medicine system for the treatment of various ailments has sparked increasing interest in recent years. Traditional medicine has employed C. indica as a home treatment for a variety of diseases.","PeriodicalId":22851,"journal":{"name":"The Journal of Phytopharmacology","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86699116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experimental evaluation on analgesic activity of Erandamoola (Ricinus communis) collected in three different seasons wsr to Dravya Samgrahana Kaala","authors":"Bingi Ashok, M. Suma, B. Sudhakara, CV Lacitha","doi":"10.31254/phyto.2022.11306","DOIUrl":"https://doi.org/10.31254/phyto.2022.11306","url":null,"abstract":"About: Dravya samgrahana kaala is an important scientific documentation mentioned in Ayurveda where there will be change in activity and phytochemical profile of plants in different seasons. Erandamoola (Ricinus communis) is an important medicinal plant where roots are particularly indicated as analgesic. As per Dravya samgrahana vidhi roots are to be collected in Hemanth-Shishira or Greeshma rutu or Pravarat rutu. Hence with this background study has been planned to evaluate analgesic activity of the Erandamoola (Ricinus cumunis) collected in Greeshma (EMG) and Pravrutritu (EMP) and Shishiraritu (EMS) using Eddy’s Hot plate method, in swiss albino mice. Materials and Methods: Roots of matured plant will be collected in three different seasons, shade dried, powdered and used for the study. Swiss Albino mice were randomly grouped into 3 groups of six animals each. Group I served as control, Group II serve as standard with administration of Tramadol whereas Group III (EMG), Group IV (EMP) and Group V (EMS) serve as the test group with administration of 200 mg/kg body weight (Erandmoola collected in Greeshma (EMG), Pravrut ritu (EMP) and Shishira ritu (EMS) respectively. Results: Erandamoola collected in greeshma and pravrut ritus show almost similar pain threshold with a slight increase in values than drug collected in greeshma ritu. Conclusion: Thus Erandamoola (Ricinus communis) can be efficiently used as an analgesic, simulatneously season or Samgrahana kaala is having a definite role on drug activity.","PeriodicalId":22851,"journal":{"name":"The Journal of Phytopharmacology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84257252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmaceutical evidence of Piper guineense on reproductive toxicityt","authors":"O. M. Onwuka, N. Nwosu, Adaobi Linda Okerulu","doi":"10.31254/phyto.2022.11315","DOIUrl":"https://doi.org/10.31254/phyto.2022.11315","url":null,"abstract":"Objectives: Nutritional value and health benefits of Piper guineense (a spice known as Uziza in Igbo language of Nigeria) cannot be overemphasized. Its therapeutic inputs on reproductive toxicity were elucidated. Study approach: Literature survey was carried out in various electronic search databases such as Google scholar, Crossref and pubmed. The survey done February 2022 – March 2022 considered literatures that reported the impact of Piper guineense on reproductive system as well as reproductive toxicity. The search keys include; “Piper guineense and reproductive health” “Piper guineense and reproductive toxicity” “Piper guineense on non-heavy metals induced reproductive toxicity” “Piper guineense on heavy metals induced reproductive toxicity” “Piper guineense on lead, cadmium, and arsenic induced reproductive toxicity”. The search keywords were used respectively and collectively. Findings: Eight (8) reports were found most appropriate for the pharmaceutical evidence of Piper guineense on reproduction; which suggests its essential therapeutic input on reproductive toxicity. Conclusively, Piper guineense is a potential vital ingredient for pharmaceuticals, used to ameliorate reproductive toxicity.","PeriodicalId":22851,"journal":{"name":"The Journal of Phytopharmacology","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83681540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytopharmacological characterization of different extracts and fractions of Cyclea peltata","authors":"R. Poonghuzhali, S. Samraj, A. Nisha, S. N. Nair, M. Priya","doi":"10.31254/phyto.2022.11304","DOIUrl":"https://doi.org/10.31254/phyto.2022.11304","url":null,"abstract":"Cyclea peltata is a shrub belongs to Menispermiaceae family and is commonly known as “Pedal” or “Pada thalli”. The plant has been used since ancient times in traditional medicine as a healing herb for the treatment of various ailments such as skin infections, wounds, antipyretic, diuretic, diabetes, asthma, jaundice and snakebite poisoning. The objective of the present study was to characterize the active phytochemical constituents present in the aqueous, methanolic and n-hexane, dichloromethane, nbutanol, water fractions of methanolic extracts of C. peltata. To analyse the potent bioactive compounds, present in the extracts and fractions, Fourier Transform Infrared Spectroscopy was used. The qualitative phytochemical screening unveiled the presence of steroids, alkaloids, glycosides, flavonoids, terpenoids, saponins in aqueous extract and alkaloids, phenols, tannins, flavonoids, terpenoids, saponins in methanolic extract. The fractions of C. peltata showed the presence of alkaloids, phenols, tannins, flavonoids, terpenoids, saponins. The Infrared Spectroscopy profiling showed the presence of alcohols, phenols, amines, carboxylic acids, aldehydes, ketones, alkenes, alkanes and aromatic compounds. From the study, it is concluded that the bioactive compounds present in the extracts and fractions of C. peltata was alkaloids, phenols, flavonoids and terpenoids which is responsible for the diverse pharmacological properties.","PeriodicalId":22851,"journal":{"name":"The Journal of Phytopharmacology","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73127327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hibiscus syriacus L.: A Critical Review of Medicinal Utility & Phytopharmacology with Mechanistic Approach","authors":"A. Balkrishna, S. Mishra, A. Singh, Deepika Srivastava, Shalini Singh, V. Arya","doi":"10.31254/phyto.2022.11312","DOIUrl":"https://doi.org/10.31254/phyto.2022.11312","url":null,"abstract":"Herbal medicine is an ancient form of medicine that has been used by humans for thousands of years. The vital systems of primordial medicines include Ayurveda, Siddha, Unani, and folk medicine and, the most developed and widely practiced medicinal system in India is Ayurveda. Hibiscus species are commonly shrubs, herbs or trees with many useful properties, of which H. syriacus is one of the prime species of the genus. It is endowed as the national flower of South Korea, commonly known as ‘Rose of Sharon’ and is found along valleys, open slopes, roadsides and sea cliffs. The plant species is used as a medicine in many diseases such as amoebic colitis, hemorrhoids, hemorrhoidal bleeding, migraine, headache, cold, cough, nausea, vomiting, abdominal pain, ascariasis, colitis, diarrhea, dysentery, dyspepsia, gas, stomach ache, hematochezia, ascariasis etc. Several biological activities of the plant are attributed to the presence of various active compounds like botulin, coumarins, fumaric acid, hydroquinone, is vitexin, linoleic acid, nonanoic acid, naringenin acid, Para hydroxybenzaldehyde, palmitic acid, Syracusans A-C, triterpenoids and vanillic acid. Some phytochemicals, including linolenic acid, palmitic acid, hydroxyhibiscone A, hibiscuses D, Syracusans A, pentacyclic triterpene esters, triterpenoid, nonanoic acid, anthocyanins, and others, are responsible for its biological importance like anti-cancer, anti-aging, anti-depressant, anti-fungal, anti-melanogenic, anti-oxidant, cytoprotective, neuroprotective, etc., Detailed information extracted by reviewing the medicinal utilities & Phytopharmacological properties, provide elaborated evidences for the application of H. syriacus in many ailments.","PeriodicalId":22851,"journal":{"name":"The Journal of Phytopharmacology","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86183077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and attitude towards COVID-19 among university students","authors":"A. Zahoor, R. Malik, Ifqa Mushtaq Siddique","doi":"10.31254/phyto.2022.11308","DOIUrl":"https://doi.org/10.31254/phyto.2022.11308","url":null,"abstract":"The present study aimed to assess the knowledge and attitude of university students about the new evolving coronavirus COVID-19. In this connection, the study was carried out among the students of SKUAST-K. A descriptive survey method was used to conduct the study. Under the jurisdiction of SKUAST-K, Shalimar, Srinagar, Faculty of Fisheries was selected by purposive sampling technique. The target population of the study comprised of the students of Faculty of Fisheries, Rangil, Ganderbal with total population size of 193. The sample of study constituted 100 students. Stratified random sampling technique was used for present study and the samples were taken proportionally with the total number of undergraduate and postgraduate students, with 62 students from U.G, 25 students from masters and 13 students from Ph.D. respectively. A self-administered questionnaire was developed to obtain information from the respondents. The data collected from the survey was analyzed using standard statistical tools like descriptive statistics such as frequency and percentage and inferential statistics such as Chi-square test. PAST 4.0 and SPSS version 20.0 was used for analysis of data. From the present study, it was concluded that majority of the respondents were having good knowledge towards COVID-19 and were very much aware about general information, cause, symptoms, transmission routes and prevention of the coronavirus disease. However, the respondents in the study were also having certain misconceptions pertaining to certain aspects of COVID-19. Majority of the respondents were of the opinion that imposing restrictions on travel to and from COVID-19 contaminated areas, closure of all educational institutes, limiting access to religious sites, isolating COVID-19 patients in special isolation wards, maintaining social distancing and locking down and quarantining whole population was a good decision by government. The respondents also showed a positive attitude towards role of media in covering COVID-19 pandemic. Furthermore, from the study, majority of the respondents disagreed that the government took all the necessary steps to tackle COVID19 virus successfully.","PeriodicalId":22851,"journal":{"name":"The Journal of Phytopharmacology","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81505053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quassia amara L.: A Comprehensive Review of its Ethnomedicinal Uses, Phytochemistry, Pharmacology and Toxicity","authors":"A. Balkrishna, Shalini Singh, Deepika Srivastava, Shalini Mishra, S. Rajput, V. Arya","doi":"10.31254/phyto.2022.11310","DOIUrl":"https://doi.org/10.31254/phyto.2022.11310","url":null,"abstract":"Quassia amara Linn., is a shrub and world widely known as ‘bitter-wood’ belongs to Simaroubaceae family. The plant grows in sandy soils of lowland & highland forests, wet forests along riverbanks and, is native to Central Mexico to Southern tropical America and Guadalupe. A Surinamese man named Quassia which gained attention for treating fevers with a secret remedy based on this herb in 18th century, which Rolande took to Sweden in 1756 and disseminated its medicinal reputation across Europe. This species consists of various constituents namely β-carbonite, indole alkaloids & primarily, the bitter compounds known as quassinoids. Various studies indicate that Q. amara possess different biological properties namely anti-diabetic, anti-inflammatory, anti-hyperglycemic, anti-leishmanial, antimalarial, anti-nociceptive, anti-ulcer, anti-fertility and sedative. Fresh bark, leaves or wood extracts are used to treat digestive problems, malaria and hepatic disorders. In-depth literature analysis revealed that the plant is least explored and possess immense medicinal values. These studies pass the new ways to explore biological potential of this plant.","PeriodicalId":22851,"journal":{"name":"The Journal of Phytopharmacology","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80541113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analyzing phytochemicals activity of Colocasia esculenta and Prunus persica against Proteus mirabilis","authors":"Kailash Chandra Semwal, Shivani Gairola, Gautam Singh Bhandari, Sushil Giri, Mayank Kumar Rana, Amit Kumar, Tejpal","doi":"10.31254/phyto.2022.11302","DOIUrl":"https://doi.org/10.31254/phyto.2022.11302","url":null,"abstract":"Serious infection of UTI is predominantly cause by Proteus mirabilis which is gram negative and motile bacteria with this if it contains antimicrobial resistance gene than it become a big problem which cannot be tackle with primary antibiotics mainly Beta-lactam antibiotics. Currently global health sector also faces antibiotic crisis. Two plants Colocasia esculenta and Prunus persica utilized for analysis of antimicrobial activity which can used to make therapy that could use against Proteus. Different-different extract of phytochemicals such as ethanol, methanol and chloroform show activity in different concentration against Proteus mirabilis.","PeriodicalId":22851,"journal":{"name":"The Journal of Phytopharmacology","volume":"85 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79193199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}