The Journal of Laryngology & Otology最新文献

{"title":"A novel approach to myringotomy simulation","authors":"Z. Kelly, A. Cao, N. Ahmedli, M. Nassar","doi":"10.1017/S0022215121004692","DOIUrl":"https://doi.org/10.1017/S0022215121004692","url":null,"abstract":"Abstract Objective In the wake of the 2019 coronavirus disease pandemic, elective cases and opportunities for clinical application have decreased, and the need for useful simulation models has become more apparent for developing surgical skills. A novel myringotomy with ventilatory tube insertion simulation model was created. Methods Residents across all levels at our institution participated in the simulation. Participants were evaluated in terms of: time of procedure, microscope positioning, cerumen removal, identification of middle ear effusion type, canal wall trauma, tympanic membrane damage and tube placement. Results Eleven residents participated. Scores ranged from 14 to 34, out of a maximum of 40. The average score among junior and senior residents was 24 and 31, respectively. The simulation was felt to be representative of the operating theatre experience. Conclusion This study demonstrates a low-cost simulation model that captures several important, nuanced aspects of myringotomy with tube insertion, often overlooked in previously reported simulations.","PeriodicalId":22757,"journal":{"name":"The Journal of Laryngology & Otology","volume":"63 1","pages":"562 - 567"},"PeriodicalIF":0.0,"publicationDate":"2022-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89069698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intracellular cytokine expression in invasive fungal sinusitis and its impact on patient outcome","authors":"P. Verma, K. Sikka, H. Verma, A. Thakar, D. Mitra, A. Saurabh, G. Singh","doi":"10.1017/S0022215122000561","DOIUrl":"https://doi.org/10.1017/S0022215122000561","url":null,"abstract":"Abstract Background Cell-mediated immunity plays an important role in host defence against fungal pathogens, regulated by differentiation of lymphocytes towards T-helper 1 or 2 cells. This study reports intracellular cytokine variation in terms of invasive fungal sinusitis type and outcome. Methods The mononuclear leukocytes of 15 patients with invasive fungal sinusitis (mucormycosis in 8, aspergillus in 7) were stained with antibodies against intracellular cytokines, after fungal antigen stimulation and culture, and immunophenotyped. Patients were followed up for six months, with clinical course categorised as improvement, worsening or death. Results The mean percentages of mononuclear cells producing interleukins 4, 5, 10 and 12, and interferon-γ, in the mucormycosis group were 0.575, 0.284, 8.661, 4.460 and 1.134, respectively, while percentages in the aspergillosis group were 0.233, 0.492, 4.196, 4.466 and 1.533. Cells producing interleukin 4 and 10 were higher in the mucormycosis group, while those producing interleukin-12 and interferon-γ were lower. Cells producing interleukins 4 and 12 were higher in patients with a poor outcome (p-values of 0.0662 and 0.0373, respectively), while those producing interferon-γ were lower (p = 0.0864). Conclusion Adaptive cell-mediated immunity is expressed differently in two categories of invasive fungal sinusitis, and the cytokine expression pattern is related to prognosis.","PeriodicalId":22757,"journal":{"name":"The Journal of Laryngology & Otology","volume":"53 1","pages":"861 - 865"},"PeriodicalIF":0.0,"publicationDate":"2022-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75333504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"JLO volume 136 issue 3 Cover and Front matter","authors":"","doi":"10.1017/s002221512200072x","DOIUrl":"https://doi.org/10.1017/s002221512200072x","url":null,"abstract":"","PeriodicalId":22757,"journal":{"name":"The Journal of Laryngology & Otology","volume":"4 1","pages":"f1 - f3"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81885171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"JLO volume 136 issue 3 Cover and Back matter","authors":"","doi":"10.1017/s0022215122000731","DOIUrl":"https://doi.org/10.1017/s0022215122000731","url":null,"abstract":"","PeriodicalId":22757,"journal":{"name":"The Journal of Laryngology & Otology","volume":"110 1","pages":"b1 - b2"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73739308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cancer diagnosis and anosmia recovery in the pandemic update, cholesteatoma diagnosis, otosclerosis in pregnancy, and no renaissance of maxillary sinus irrigation","authors":"E. Fisher, J. Fishman","doi":"10.1017/S0022215122000688","DOIUrl":"https://doi.org/10.1017/S0022215122000688","url":null,"abstract":"The latest coronavirus disease 2019 (Covid-19) related articles in The Journal of Laryngology & Otology include an update on head and neck cancer referrals and diagnosis during the pandemic from Wolverhampton. We have covered the topic previously in The Journal, and have articles from before the pandemic for comparison. The 62 per cent reduction in fast-track referrals in early 2020 (compared to 2019) during the study period is of the same order of magnitude that has been experienced elsewhere. The authors highlight that this major change in patient illness related behaviour forms part of the hidden cost of the pandemic. A similar detection rate in the two time periods suggests that there is a cohort of undiagnosed patients in the community, which is worrying, despite the acknowledged limitations of the ‘two-week wait’ system of cancer diagnosis. The anosmia story during the pandemic is updated this month by a study from Italy, which found that over one-third of anosmic Covid-19 patients still had symptoms after over five months, and those who had a complete recovery tended to have a shorter duration of symptoms. A long duration of symptomatic anosmia predicted incomplete recovery. An earlier (small) study from Milan found that 91 per cent of patients had some degree of recovery, with 53 per cent showing total recovery at eight months. Cholesteatoma diagnosis by special sequences of magnetic resonance imaging (MRI) has allowed many patients to avoid costly and inconvenient secondor third-look tympanoplasty operations, as the technique has a high predictive value. Equivocal cases might lead to a negative exploration. This issue’s study of MRI diagnosis of cholesteatoma, from Newcastle upon Tyne, found that, in equivocal cases, when the lesion in the middle-ear cleft has higher signal intensity compared with the ipsilateral temporal lobe, there is high statistical probability of cholesteatoma diagnosis. Human papilloma virus (HPV) and its relevance to head and neck tumours continue to stimulate interest; previous work has investigated the prevalence in paediatric tonsils, which has been low. The paper in this issue, from London, Ontario (Canada), examined paediatric tonsillectomy specimens in 102 children aged 0–18 years, and found that none contained relevant viral subtypes as determined by a quantitative polymerase chain reaction test. This suggests no vertical transmission of the virus in this population, unless the virus is latent, as would be expected from a primarily sexually-transmitted disease, and strengthens the push for HPV vaccination prior to the age of sexual activity. The growing interest in biofilms in inflammatory disorders, and the efficacy of saline douches in the management of chronic rhinosinusitis, has made many rhinologists wonder if the old-fashioned maxillary sinus washout (‘antral lavage’) had some merit and might reappear. This issue has a study from Haifa, Israel, in which patients with chronic rhinosinusitis were treate","PeriodicalId":22757,"journal":{"name":"The Journal of Laryngology & Otology","volume":"124 1","pages":"189 - 190"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88091426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of coronavirus disease 2019 on the head and neck cancer pathway in the West of Scotland","authors":"I. Drake, A. Rogers, M. Stewart, J. Montgomery","doi":"10.1017/S0022215122000603","DOIUrl":"https://doi.org/10.1017/S0022215122000603","url":null,"abstract":"Abstract Objective The coronavirus disease 2019 pandemic has greatly disrupted head and neck cancer services in the West of Scotland. This study aimed to assess the impact of the first wave of the pandemic on cancer waiting times. Methods A retrospective review of multidisciplinary team records was undertaken between March and May in 2019 and the same months in 2020. Time-to-diagnosis and time-to-treatment for new cancers treated with curative intent were compared between the study periods, and subclassified by referral pathway. Results A total of 236 new cancer patients were included. During the pandemic, pathways benefitted from reduced diagnostic and treatment times resulting from the restructuring of service provisions. A 75 per cent reduction in secondary care referrals and a 33 per cent increase in urgent suspicion of cancer referrals were observed in 2020. Conclusion Head and neck cancer pathway times did not suffer because of the coronavirus pandemic. Innovations introduced to mitigate issues brought about by coronavirus benefitted patients, led to a more streamlined service, and improved diagnostic and treatment target compliance.","PeriodicalId":22757,"journal":{"name":"The Journal of Laryngology & Otology","volume":"2 1","pages":"535 - 539"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77601733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Head and Neck Oncology: A Concise Guide. Akheel Mohammad, Ashmi Wadhwania ISBN 9780367421311 Published by CRC Press 2021 180 Pages £69.99","authors":"L. Flood","doi":"10.1017/s0022215122000524","DOIUrl":"https://doi.org/10.1017/s0022215122000524","url":null,"abstract":"I did find it hard to review this book, based solely on my reading off a desktop monitor, but, at a time when new texts are few and far between, this beggar will not be too choosy. Although only an e-book is available to reviewers, it seems there is at least a soft back version out there and, from this publisher, I am sure it is well presented. This ‘Concise Guide’ does not follow the usual practice of an international multi-authorship, supervised by a couple of eminent editors. Instead, it is all the work of just two authors (even though the title page still calls them ‘editors’). That has obvious advantages for consistency of style throughout and adherence to deadlines, but, equally, it does place demands on the authors to cover such a wide field comprehensively. The Preface suggests this book is aimed at the vast Indian market and is best seen as an introduction to the subject for trainees. It explains that all management recommendations are based on the guidelines of the National Comprehensive Cancer Network, which certainly does prove to be the case. Most chapters draw heavily on the guidance, quoted word for word, but also on the internationally recognised Union for International Cancer Control tumour–node–metastasis (TNM) classification of tumour staging, and for many chapters these two resources are the sole content. Notably, the work of John Watkinson in Stell and Maran’s Textbook of Head and Neck Surgery (CRC Press, 2011) is very widely referenced in many chapters. This must raise doubts about the novelty of the book’s content. Having these two online resources printed out, ready to hand (and frankly far more readable here than on the National Comprehensive Cancer Network site, which is murder to navigate and read), may well be of advantage to trainees, although again such content is freely available, if you can read off a monitor of course. Randomly scanning through the content, I was struck by some errors and omissions. In the chapter on laryngeal cancer, I was surprised to see Fig. 13.1 telling me that a T3 tumour meant a ‘paralysed’ vocal fold, very different to a fixed vocal fold of course. I confess an obvious personal interest in the ‘Occult Primary’ chapter, but read with persisting incomprehension ‘The exact incidence of epidemiology is unknown, but the occult primary of the head and neck has an incidence of 3–7% presenting with squamous cell carcinoma of the neck’. Fine needle aspiration cytology is recommended, but most would now consider conducting an ultrasound guided needle biopsy, especially as it checks human papilloma virus (HPV) status, with obvious clues as to the site of the primary tumour. Curiously, HPV receives but a single mention throughout the book, in a chapter on oncogenes, and then purely in a list of the culprits. In the ‘Oropharyngeal Cancer’ chapter, the brief coverage is limited to the National Comprehensive Cancer Network guidelines for p16 negative tumours, without reproducing their guidance on p16 pos","PeriodicalId":22757,"journal":{"name":"The Journal of Laryngology & Otology","volume":"109 1","pages":"570 - 571"},"PeriodicalIF":0.0,"publicationDate":"2022-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73375693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Operative Surgery for Head and Neck Tumors Edited By Jagdeep Thakur, Ripu Daman Arora ISBN 9781032155814 Published 2022 by CRC Press 274 Pages £74.99","authors":"L. Flood","doi":"10.1017/s0022215122000500","DOIUrl":"https://doi.org/10.1017/s0022215122000500","url":null,"abstract":"","PeriodicalId":22757,"journal":{"name":"The Journal of Laryngology & Otology","volume":"88 1","pages":"375 - 375"},"PeriodicalIF":0.0,"publicationDate":"2022-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74523519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Art and Science of Extended Deep Plane Facelifting and Complementary Facial Rejuvenation Procedures A A Jacono Quality Medical Publishing, 2021 ISBN 978 1 57626 460 7 pp 500 Price US$395.00","authors":"D. Whitehead","doi":"10.1017/s0022215122000378","DOIUrl":"https://doi.org/10.1017/s0022215122000378","url":null,"abstract":"","PeriodicalId":22757,"journal":{"name":"The Journal of Laryngology & Otology","volume":"4 1","pages":"568 - 569"},"PeriodicalIF":0.0,"publicationDate":"2022-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80024819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"JLO volume 136 issue 2 Cover and Front matter","authors":"","doi":"10.1017/s0022215122000573","DOIUrl":"https://doi.org/10.1017/s0022215122000573","url":null,"abstract":"","PeriodicalId":22757,"journal":{"name":"The Journal of Laryngology & Otology","volume":"24 1","pages":"f1 - f3"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81959467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}