{"title":"Introductory Chapter: Radiation Exposure, Dose and Protection","authors":"O. A. Osibote","doi":"10.5772/intechopen.89041","DOIUrl":"https://doi.org/10.5772/intechopen.89041","url":null,"abstract":"","PeriodicalId":227451,"journal":{"name":"Ionizing and Non-ionizing Radiation","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125471543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Tandel, D. Trivedi, Aditi Mohan Krishnan, S. Dalai
{"title":"Application of Radiation Technology: A Novel Vaccine Approach to Induce Protective Immunity against Malaria Infection","authors":"N. Tandel, D. Trivedi, Aditi Mohan Krishnan, S. Dalai","doi":"10.5772/intechopen.85491","DOIUrl":"https://doi.org/10.5772/intechopen.85491","url":null,"abstract":"Among the numerous infectious diseases, malaria remains a major health challenge. Despite the various approaches adopted for the vector control and availability of antimalarial drugs, the success of malaria eradication is dampened by the spread of drug and insecticide resistance, unavailability of proper diagnostic treatment and successful vaccine. Among the various approaches, vaccination with the aim of developing protective immunity is the most suited, safe and reliable approach for the entire mankind. Numerous approaches are in use for vaccine development; however, they suffer from the drawbacks that immunity developed is short lived and are both species- and stage-specific. Of late, radiation sterilization has drawn the attention in the vaccine development due to its advantages over the conventional methods, and successful clinical trials of irradiated vaccines against the pathogens and tumor. Recently, a novel approach of genetically attenuated sporozoites (PfRAS, PfSPZ, PFSPZ-GA1 sporozoites vaccines) has shown promising results by generating protective immunity against the homologous and heterogenous infection in the clinical trials. Radiation techniques have also been beneficial in control-ling the insects by sterility technique. In this chapter, we have recapitulated the role of radiation biology in the malaria vaccine development with its current status and future challenges associated with the development of radiation attenuated parasite vaccine.","PeriodicalId":227451,"journal":{"name":"Ionizing and Non-ionizing Radiation","volume":"272 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124403582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Monitoring of Natural Radioactivity in Drinking Water and Food with Emphasis on Alpha-Emitting Radionuclides","authors":"M. Zehringer","doi":"10.5772/intechopen.90166","DOIUrl":"https://doi.org/10.5772/intechopen.90166","url":null,"abstract":"Alpha spectrometry is an indispensable technique in the radiology lab for the analysis of natural radionuclides. While the powerful ICP/MS is used more and more for the analysis of uranium and thorium, other radionuclides, such as 226 Ra, are difficult to analyze with this technique due to their very high specific activities. The following chapter is introduced by a description of the problems, which may occur when working in the ultra-trace level. A description of the commonly used extraction and enrichment techniques for alpha nuclides and a short survey of the commonly applied detection techniques are given. The main application of alpha spectrometry in our laboratory is the monitoring of tap and mineral waters. Besides water, some specific food categories, such as fish, seafood, spices or healing earths, are monitored for their content of natural radionuclides.","PeriodicalId":227451,"journal":{"name":"Ionizing and Non-ionizing Radiation","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131557121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Felipe P. Perez, J. Rizkalla, M. Jeffers, P. Salama, Cristina N. Perez Chumbiauca, M. Rizkalla
{"title":"The Effect of Repeated Electromagnetic Fields Stimulation in Biological Systems","authors":"Felipe P. Perez, J. Rizkalla, M. Jeffers, P. Salama, Cristina N. Perez Chumbiauca, M. Rizkalla","doi":"10.5772/intechopen.89668","DOIUrl":"https://doi.org/10.5772/intechopen.89668","url":null,"abstract":"The effects of electromagnetic fields on living organs have been explored with the use of both biological experimentation and computer simulations. In this paper we will examine the effects of the repeated electromagnetic field stimulation (REMFS) on cell cultures, mouse models, and computer simulations for diagnostic purposes. In our biological experiments we used 50 MHz and 64 MHz since this is approved in MRI systems. REMFS upregulated pathways that control the aging process such as proteostasis. REMFS delayed and reversed cellular senescence in mouse and human cell cultures. More recently we determined that REMFS decreases toxic protein beta amyloid levels, which is the cause of Alzheimer’s disease (AD), in human neuronal cultures. The mechanism of these effects is the reactivation of the heat shock factor 1 (HSF1). HSF1 activation is a quantum effect of the EMF-oscillations on the water that surrounds a long non-coding RNA, allowing it to then bind and activate the HSF1. We also performed electromagnetic (EM) computer simulations of virtual prototypes of bone cancer, femur fracture, and diabetic foot ulcers utilizing different frequencies and power applications to build an accurate differential diagnosis. These applications indicate the feasibility of subsequent practical models for diagnosing and treating human diseases.","PeriodicalId":227451,"journal":{"name":"Ionizing and Non-ionizing Radiation","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134252165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mario Marcelo Figueroa de la Cruz, Roberto Daniel Breslin
{"title":"Study of Non-predictive Patterns of Non-Ionizing Radiation in the City of Salta in Argentine","authors":"Mario Marcelo Figueroa de la Cruz, Roberto Daniel Breslin","doi":"10.5772/INTECHOPEN.84717","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.84717","url":null,"abstract":"Non-ionizing radiation (NIR) is a subject of continuous debate despite having been regulated internationally and at the level of organizations in all countries. This debate is focused on the level of population exposure to non-ionizing radiation density, since there is no certain evidence of the level of safety of the values adopted ranging from 0.2 mW/cm 2 to 0.2 uW/cm 2 according to the regulations of each state. The radiation precisions are made with models that evolve to take into account most of the factors that can attenuate the radiation emitted from an antenna from free space to models that take reflection and diffraction as attenuation factors. However, our work deepens in a phenomenon that is verified in measurement campaigns that is one of the values that do not fit with predictive models and that, on the contrary instead of showing attenuation, have higher values than expected. This work shows the results of observation campaigns of these points and their relationship with environmental conditions, which present diverse probabilities to explain their condition.","PeriodicalId":227451,"journal":{"name":"Ionizing and Non-ionizing Radiation","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125629926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Takuya Ohdaira, Kanna Meguro, Kazuki Komatsu, Rina Syoji, Yohei Fujishima, V. Goh, K. Kasai, K. Ariyoshi, A. Nakata, Yusuke Urushihara, Kazuma Koarai, Y. Kino, T. Sekine, Masatoshi Suzuki, A. Takahasi, Y. Shimizu, H. Shinoda, Mitsuaki Yoshida, M. Fukumoto, H. Yamashiro, T. Miura
{"title":"Analysis of Radioactive Elements in Testes of Large Japanese Field Mice Using an Electron Probe Micro-Analyser after the Fukushima Accident","authors":"Takuya Ohdaira, Kanna Meguro, Kazuki Komatsu, Rina Syoji, Yohei Fujishima, V. Goh, K. Kasai, K. Ariyoshi, A. Nakata, Yusuke Urushihara, Kazuma Koarai, Y. Kino, T. Sekine, Masatoshi Suzuki, A. Takahasi, Y. Shimizu, H. Shinoda, Mitsuaki Yoshida, M. Fukumoto, H. Yamashiro, T. Miura","doi":"10.5772/INTECHOPEN.84634","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.84634","url":null,"abstract":"The Fukushima Daiichi nuclear power plant (FDNPP) accident drew global attention to the health risks of radiation exposure. The large Japanese field mice ( Apodemus speciosus ) are rodents endemic to, and distributed throughout, Japan. This wild rodent live in and around the ex-evacuation zone on the ground surface and/or underground. In this study, we evaluated the effect of chronic radiation exposure associated with FDNPP accident on the testes of large Japanese field mice. Morphological analysis and electron-prove X-ray microanalysis (EPMA) was undertaken on the testes. Morphological analysis of testes based on H&E staining showed that the spermatogenesis was observed normally in the breeding season of wild mice in the heavily contaminated area. However, caesium (Cs) was not detected in all testes of wild mice from FDNPP ex-evacuation zone. In conclusion, even if the testes and the process of spermatogenesis are hypersensitive to radiation, we could not detect radiation effects on the spermatogenesis and Cs in the examined large Japanese field mice testes following chronic radiation exposure associated with the FDNPP accident.","PeriodicalId":227451,"journal":{"name":"Ionizing and Non-ionizing Radiation","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114688393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Environmental Radiation: Natural Radioactivity Monitoring","authors":"I. M. Musa","doi":"10.5772/INTECHOPEN.85115","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.85115","url":null,"abstract":"People are continuously exposed to ionizing radiation from many sources, including natural radioactive substances that are produced in the atmosphere and on Earth, in addition to radionuclides manufactured for various applications. Exposures vary among different places depending on many parameters. There are regions with considerably high natural background radiation while most places classified as low to medium levels. This noticeable interest pronounced worldwide is radioactivity monitoring and wide surveys by many countries. This is useful for the assessment of public as well as creating baseline if changes in the levels due to activities and practices take place. Good management of protecting the environment is to establish baseline data of high quality with efficient measurements. Natural radioactivity monitoring in view of radiation and environmental protection is presented in this chapter. It will shed the light on rapid methods describing the measurement of radionuclides and assessment of exposure to human. It presents a summary of methods of radiation dose calculations that individual may be exposed with some numerical examples. The chapter also presents methods for predicting the spatial distribution of radiological quantities using geographical information system. Environmental measurements may be costly and time-consuming practices; hence, thoughts to reduce time force itself in this chapter.","PeriodicalId":227451,"journal":{"name":"Ionizing and Non-ionizing Radiation","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116784152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dosimetry for Use in Preparedness and Response to Radiological and Nuclear Emergency","authors":"V. Kutkov","doi":"10.5772/INTECHOPEN.83370","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.83370","url":null,"abstract":"Lessons learned from responses to past radiological and nuclear emergencies have shown that more guidance is needed for assessing doses to those who were affected in emergency exposure situation. The chapter introduces system of dosimetric quantities for use in emergency preparedness and response to nuclear or radiological emergency, which includes RBE-weighted absorbed dose in tissue or organ for evaluation of the risk of severe deterministic effects, equivalent dose in tissue or organ for evaluation of the risk of stochastic effects, and effective dose for evaluation of the detriment due to undetectable stochastic effects. The chapter also provides internationally proved criteria for protection of individual in emergency exposure situation and framework of dose and risk assessment in an emergency. The special attention has been put on evaluation of available sources of dosimetric data needed for dose and risk assessment in an emergency.","PeriodicalId":227451,"journal":{"name":"Ionizing and Non-ionizing Radiation","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115716287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spinal Stereotactic Body Radiotherapy (SBRT) Planning Techniques","authors":"Jina Kim, Y. Seol, H. Jang, Y. Kang","doi":"10.5772/INTECHOPEN.83515","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.83515","url":null,"abstract":"Stereotactic body radiotherapy (SBRT) delivers a highly conformal and hypofractionated radiation dose to a small target with minimal radiation applied to the surrounding areas. The spine is an ideal site for SBRT owing to its relative immobility, the potential clinical benefits of high-dose delivery to this area, and the presence of adjacent critical structures such as the spinal cord, esophagus, and bowel. However, with the potential for radiation myelopathy if the dose is delivered inaccurately or if the spinal cord dose limit is set too high, proper treatment planning techniques for SBRT are important. Intensity modulation techniques are useful for spinal SBRT because of a rapid dose falloff and spinal cord avoidance. In this chapter, various planning techniques will be discussed and reviewed.","PeriodicalId":227451,"journal":{"name":"Ionizing and Non-ionizing Radiation","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130713156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic Imaging Safety and Protection: A Collective Interaction and Decision-Making Processes and Procedures toward an Effective Health Outcome","authors":"C. Makanjee","doi":"10.5772/INTECHOPEN.82844","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.82844","url":null,"abstract":"This chapter will focus on the safety and protection in utilization of radiation and nonradiation imaging modalities within a medical encounter in health institutional context. The challenges of ease of access on the one hand regarding a referral versus accessing of these imaging services. The roles and responsibilities of the diverse range of professionals in the medical encounter are in ensuring that an effective decision-making is made at each point in time. The importance of communication, coordination, collaboration, and alignment is in ensuring that the care and safety of the patient is not compromised. Thus, the chore essence of provider is patient-centered care, that is, from the point of the initiation of the referral to the outcomes of an effective medical treatment and management plan. The role of the imaging investigation and its value is outweighing the risks versus harm through these chains of events and beyond.","PeriodicalId":227451,"journal":{"name":"Ionizing and Non-ionizing Radiation","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121111136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}