Complex Issues of Cardiovascular Diseases最新文献

{"title":"Impact of preoperative cognitive impairment on changes in electrical activity of the brain in patients undergoing combined carotid endarterectomy and coronary artery bypass grafting","authors":"I. Tarasova, D. Kupriyanova, O. Trubnikova, A. Sosnina, I. Syrova, I. Kukhareva, O. Maleva, S. Ivanov, O. Barbarash","doi":"10.17802/2306-1278-2023-12-2-24-34","DOIUrl":"https://doi.org/10.17802/2306-1278-2023-12-2-24-34","url":null,"abstract":"HighlightsThe presence of preoperative mild cognitive impairment (MCI) in patients undergoing combined carotid endarterectomy and coronary artery bypass grafting is associated with an increased theta activity at the frontal and parieto-occipital regions of both hemispheres after surgery. AbstractAim. To study the impact of preoperative cognitive impairment on changes in electrical activity of the brain in patients undergoing combined carotid endarterectomy and coronary artery bypass grafting.Methods. Sixty-three patients undergoing combined carotid endarterectomy (CAE) and coronary artery bypass grafting (CABG) were included in the study. The patients were divided into three groups, depending on the preoperative cognitive functions: without cognitive impairment (n = 17), with MCI (n = 29), and with severe cognitive impairment (n = 17). High-resolution electroencephalography (EEG) (62 channels, bandpass filtered between 0.1–50.0 Hz, sampling rate of 1000 Hz) was performed 3–5 days before and 7–10 days after surgery.Results. Patients with severe cognitive impairment at baseline presented with higher theta activity at the frontal region of the left hemisphere compared to patients without cognitive impairment and patients with MCI (p = 0.048). At the same time, patients with MCI showed the most pronounced theta activity increase after surgery compared to preoperative levels at the frontal and parieto-occipital cortical regions of both the left and right hemispheres (p≤0.05). Postoperative changes of theta activity in patients with severe cognitive impairment were minimal and statistically insignificant.Conclusion. Patients without severe preoperative cognitive impairment presented with higher grade brain dysfunction in the form of increased theta activity at the frontal and parieto-occipital regions after combined CAE and CABG. A smaller decrease in theta power after surgery in patients with severe preoperative cognitive impairment, on the one hand, can indicate compensation after cerebral ischemia and resistance to hypoperfusion during on-pump cardiac surgery, and on the other, can be a manifestation of the ceiling effect and insufficiency of brain functional reserves.","PeriodicalId":227108,"journal":{"name":"Complex Issues of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123269003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of acute coronary graft failure and subsequent urgent endovascular revascularization after planned coronary artery bypass grafting on hospital outcome","authors":"A. A. Semagin, O. P. Lukin, A. Fokin","doi":"10.17802/2306-1278-2023-12-2-46-56","DOIUrl":"https://doi.org/10.17802/2306-1278-2023-12-2-46-56","url":null,"abstract":"Highlights The authors conducted a comparative analysis of early postoperative complications, mortality and economic costs in patients who underwent additional urgent endovascular revascularization and patients with standard postoperative period.There are statistically significant differences between the groups in terms of the number of resternotomies performed, the need for transfusable blood components and economic costs.It is necessary to introduce routine intraoperative quality control of the intervention, and a set of measures aimed at early detection of coronary graft failure in real clinical practice. Abstract Aim. To assess the impact of coronary graft failure and subsequent urgent endovascular revascularization in the early postoperative period after elective coronary artery bypass grafting on hospital outcome.Materials and methods. 8801 patients underwent isolated coronary artery bypass grafting at the Federal State Budgetary Institution “Federal Center for Cardiovascular Surgery” of the Ministry of Health of the Russian Federation in Chelyabinsk from 2011 to 2020. Inclusion criteria were as follows: patients with stable coronary heart disease, patients undergoing elective coronary artery bypass grafting. Exclusion criteria were as follows: patients with unstable angina and acute myocardial infarction who underwent urgent revascularization. The primary endpoint was hospital mortality, secondary endpoints are bleeding requiring resternotomy, acute abdominal and infectious complications, and multiple organ failure. Due to suspected acute myocardial injury, 196 (2.23%) patients underwent urgent coronary angiography, and according to angiogram, additional endovascular correction was performed in 60 (0.68%) patients (the group I). To assess the impact of coronary graft failure and subsequent revascularization on hospital outcome we have analyzed: hospital mortality, complications in the early postoperative period, financial costs. Moreover, we have formed the group II of 60 people with uncomplicated postoperative period for comparative analysis.Results. Of 196 (2.23%) patients who underwent urgent angiography 60 (0.68%) patients required stenting of native coronary arteries or conduits due to coronary graft failure. Hospital mortality in the group with complicated postoperative period was 10 % (6 cases), hemorrhagic complications occurred in 13 (21.7%) patients, acute abdomen was noted in 4 patients, and sternal wound infection was noted in 5 patients, hemodialysis due to multiple organ failure was performed in 5 patients. An intergroup comparative analysis revealed a clear trend towards an increase in deaths in the group I (n = 6/10%) compared to the group II (n = 1/1.7%), however, there were no significant differences (p = 0.11F). Hemorrhagic complications occurred significantly higher in group I (13/21.7% versus 1/1.7%, p = 0.001F); there were no statistically significant differences associated with the other complications. The number of ","PeriodicalId":227108,"journal":{"name":"Complex Issues of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128181027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EVOLUTION OF THORACOSCOPIC TREATMENT OF ATRIAL FIBRILLATION: FROM INCEPTION TO CONTEMPORARY APPROACHES","authors":"A. Revishvili, E. Artyukhina, E. Strebkova, E. Malyshenko, M. Kadyrova","doi":"10.17802/2306-1278-2023-12-2-107-121","DOIUrl":"https://doi.org/10.17802/2306-1278-2023-12-2-107-121","url":null,"abstract":"HighlightsThe development and implementation of video-assisted thoracoscopic atrial fibrillation ablation since 2005 by R. Wolf and colleagues have undergone a number of modifications for improvement and simplification. A study of the evolutionary development of thoracoscopic ablation of atrial fibrillation is necessary to optimize ablation recruitment and surgical technique for different forms of atrial fibrillation. AbstractThere is a variety of treatments for atrial fibrillation (AF): therapeutic, interventional and surgical. The effectiveness of these methods varies significantly depending on the form of AF. For a long time, surgery was considered the only highly effective treatment for AF. In modern arrhythmology, «Maze IV» and its modifications are considered only as a simultaneous procedure in cardiac surgery. The work of M. Haïssaguerre et al. has established that the main focus of catheter ablation (CA) in AF should be the pulmonary veins, but their isolation in non-paroxysmal AF is questionable. This discovery has stimulated the development of alternative treatment modalities for resistant AF. Recently, video-assisted thoracoscopic epicardial ablation (TSA), which does not require sternotomy, cardiopulmonary bypass and cardioplegia, has been increasingly preferred. TSA of AF is an alternative surgical treatment for isolated forms of AF on the working heart. This procedure may include: pulmonary vein ablation, posterior left atrial wall and pulmonary vein ablation and left atrial appendage exclusion, but its effectiveness varies considerably due to the heterogeneity of patients, surgical technique and follow-up period. The aim of this review is to provide data on the evolutionary development of thoracoscopic ablation of AF depending on the choice of surgical access, ablation line set and ablation device.","PeriodicalId":227108,"journal":{"name":"Complex Issues of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127013845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PROVISION OF HIGH-TECH CARDIOVASCULAR CARE TO RESIDENTS OF THE RUSSIAN FEDERATION REGIONS IN 2021","authors":"E. Golukhova, V. Semenov, E. B. Milievskaya, V. Pryanishnikov","doi":"10.17802/2306-1278-2023-12-2-77-87","DOIUrl":"https://doi.org/10.17802/2306-1278-2023-12-2-77-87","url":null,"abstract":"Highlights: The article presents data on the availability of various types of high-tech cardiovascular care services to residents of subjects of the Russian Federation. The authors used original methodology based on the data of the Healthcare Administration of the subjects of the Russian Federation. The obtained data were compared with the data from the Federal Tax Service Office No. 12, and 14, demographic and socio-economic indicators of the subjects of the Russian Federation. The results of the analysis open up new opportunities for studying the causes of pronounced differences in the provision of high-tech cardiovascular care to the population of the country's regions and taking appropriate regulatory measures, thus contributing to practical healthcare. Aim. To analyze the provision of high-tech cardiovascular care (HTCC) to residents of the Russian Federation regions in 2021 taking into account social and economic factors.Methods. The data from the original form designed in A.N. Bakulev National Medical Research Center of Cardiovascular Surgery containing information on the number of patients who underwent cardiovascular surgeries were compared with the data from the Federal Tax Service Office follow-up forms No.12 and No.14, taking into account demographic and social-economic factors of the RF regions according to the Federal Service of State Statistics. 74 regions were included into the analysis. The following methods of univariate statistics were used: Spearman’s and Kendall’s rank correlation, measures of central tendency and variance were calculated. Intergroup comparison was carried out using Mann-Whitney two-tailed test and Kruskall-Wallis one-way analysis of variance.Results. The mean provision of HTCC included in the Section I of the Free Health Care Policies for Citizens (HTCC-1) was 1910 surgeries per 1 million population, provision of HTCC included in the Section II (HTCC-2) – was 789.5, respectively. We have noted the negative correlation between the amount of HTCC -1 and HTCC -2 surgeries and hypertension mortality (p = 0.034). The mortality from other acute CAD correlated negatively with the provision of coronary artery bypass grafting (CABG, p = 0.034). The authors also noted the negative correlation between the provision of HTCC -2 surgeries and circulatory diseases (CD) overall incidence (p = 0.032), primary CD incidence (p = 0.014), CAD overall incidence (p = 0.034) and more. The region’s economic development level influenced the provision of HTCC -2 surgeries. The positive correlation coefficients were obtained for per capita income (p = 0.004), median per capita income (p = 0.002), real amount of granted pensions (p = 0.003) and other parameters. The number of CABG per 1 million and life expectancy was higher in the RF regions where CABG was performed locally compared to the regions that did not provide cardiovascular care (205.82 vs 165.55 and 69.49 vs 68.64).Conclusion. The indicators of HTCC-1 and HTCC-2 provision in ","PeriodicalId":227108,"journal":{"name":"Complex Issues of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128788394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LINGUISTIC AND COGNITIVE DISORDERS IN 4-6 YEARS OLD PATIENTS WITH CONGENITAL HEART DEFECTS BEFORE AND AFTER SURGICAL CORRECTION","authors":"A. A. Rumiantseva, L. N. Igisheva, V. Kameneva","doi":"10.17802/2306-1278-2023-12-2-14-23","DOIUrl":"https://doi.org/10.17802/2306-1278-2023-12-2-14-23","url":null,"abstract":"Highlights There are data about speech disorders in children with congenital heart defects. The results of the speech research in 4–6 years old children before and after surgery are described according to the surgical tactics.    Aim. To compare linguistic and cognitive disorders in in 4–6 years old children with congenital heart defects before and after surgery.Methods. A prospective investigation of group of children (n = 92) with septal heart defects was done before and after surgery and within decreed terms: in 1 and 2 years after the surgical correction of congenital heart defects in cardiopulmonary bypass or in cath-lab in Research Institute for Complex Issues of Cardiovascular Diseases. The anamnesis, clinical and hemodynamic aspects were studied before and after surgery, as well as early postoperative period, residual hemodynamic disorders and speech diagnostic was also done.Results. 57% children had different speech disorders (general or delayed speech development) in preoperative period. It was made worse by cardiosurgery: the number of children with speech disorders increased to 63% in a year after surgery and was 59.8% in 2 years, while there was a positive dynamic in clinical and hemodynamic aspects.     Conclusion. There are speech disorders in children with septal heart defects after surgery in long-term postoperative period despite of clinical and hemodynamic normalization. That can lead to the real risks and quality of life worsening in general in the absence of timely correction. ","PeriodicalId":227108,"journal":{"name":"Complex Issues of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121565344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical registry on patient population with Multifocal Atherosclerosis in the Russian Federation and Eurasian countries – KAMMA","authors":"T. Batluk, E. Tarlovskaya, G. Arutyunov, N. Koziolova, A. Chesnikova, O. Barbarash, A. Arutyunov","doi":"10.17802/2306-1278-2023-12-2-6-13","DOIUrl":"https://doi.org/10.17802/2306-1278-2023-12-2-6-13","url":null,"abstract":"HighlightsDeveloping international registry that would unify different patient populations not represented in other registries and studies, and include patients with both manifested and subclinical atherosclerosis, is crucial for cardiovascular field. The collected data can be used in national guidelines, teaching and learning guides, and in clinical practice. AbstractMultifocal atherosclerosis (MFA) is one of the key issues in modern medicine. Several vascular beds are involved in the pathological process in every fifth patient with detected atherosclerosis. Moreover, patients with MFA have high risk of ischemic events, lower quality of life, shorter life expectancy and disability. “The Eurasian Association of Internal medicine” proposed to create a registry on real clinical practice in order to collect data on the frequency, detection methods, clinical course, risk factors and outcomes of patients with MFA in specialized centers in Russia and Commonwealth of Independent States (Republic of Kazakhstan, Republic of Uzbekistan, Republic of Belarus).","PeriodicalId":227108,"journal":{"name":"Complex Issues of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128173545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ANEMIA AND LONG-TERM SURVIVAL OF PATIENTS AFTER MITRAL VALVE SURGERY","authors":"D. A. Matsuganov, M. Nuzhdin","doi":"10.17802/2306-1278-2023-12-2-156-162","DOIUrl":"https://doi.org/10.17802/2306-1278-2023-12-2-156-162","url":null,"abstract":"HighlightsThe authors have studied anemia`s impact on the long-term mortality after mitral valve surgery. The research results indicate the need to address this modifiable factor in the preoperative period. Aim. To analyze the impact of anemia on the long-term survival of patients after mitral valve surgery.Methods. The study included 103 patients, 46 of them were men, 57 were women. Thirteen patients presented with anemia before surgery, and 90 patients did not have anemia. The survival rate of patients was compared using the Kaplan-Meier estimate.Results. The survival rate after surgery in the group of patients without anemia was higher compared with patients with anemia (p = 0,002). By the end of the follow-up period, the survival rate among patients without anemia reached 50.2%, whereas among patients with anemia it was 0.0%.Conclusion. Anemia is an independent predictor of complications in the postoperative period in patients with low preoperative hemoglobin levels. According to the results, the presence of anemia increases the risk of adverse events by 7.71 times in the preoperative period. Moreover, patients without anemia had the highest (up to 50.2%) survival rate in the long-term period, while patients with anemia had a survival rate equal to 0.0%.","PeriodicalId":227108,"journal":{"name":"Complex Issues of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132061117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PULMONARY ARTERY INTIMAL SARCOMA MIMICKING PULMONARY EMBOLISM: SURGICAL TREATMENT RESULTS","authors":"S. Fedorov, A. P. Medvedev, L. M. Tselousova, S. A. Zhurko, Vladimir A. Chiginev, O. V. Krasnikova, N. V. Rogulina, V. Pichugin, Yu.D. Brichkin, A. Gordetsov, R. A. Deryabin, Anastasia R. Kondratieva","doi":"10.17802/2306-1278-2023-12-2-196-206","DOIUrl":"https://doi.org/10.17802/2306-1278-2023-12-2-196-206","url":null,"abstract":"HighlightsThe article describes a rare case of surgical treatment of pulmonary artery intimal sarcoma. The authors analyzed the causes for incorrect diagnosis of pulmonary embolism in detail, and proposed alternative options for distinguishing the diseases under consideration. Moreover, the authors analyzed different surgical treatment modalities of intracardial sarcomas, and demonstrated the prospect of using molecular hydrogen as a component of an anesthetics during surgical interventions with cardiopulmonary bypass. AbstractThe article describes a rare clinical case of a patient with pulmonary artery sarcoma. The absence of specific symptoms of sarcoma, as well as features of developing cardiovascular and respiratory failure, characteristic of pulmonary embolism, contributed to the incorrect diagnosis. The article analyzes the main problems of primary diagnostics, and proposes new parameters for evaluating manifesting symptoms and the results of additional examination, which should improve the results of surgical treatment of malignant tumors.","PeriodicalId":227108,"journal":{"name":"Complex Issues of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127892440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LONG-TERM HEMODYNAMIC OUTCOMES OF DIFFERENT AORTIC VALVE INTERVENTIONS – A REVIEW OF COMPARATIVE STUDIES","authors":"R. Komarov, S. S. Badalyan, S. V. Chernyavsky, A. M. Ismailbayev, Soslan T. Enginoyev, Maruar B. Mukanova, F. S. Gafurov, Nargiza M. Babakulova, Richmond Owusu","doi":"10.17802/2306-1278-2023-12-2-122-137","DOIUrl":"https://doi.org/10.17802/2306-1278-2023-12-2-122-137","url":null,"abstract":"Highlights Valve replacements using mechanical prostheses are not inferior, and sometimes even advantageous to bioprostheses in terms of transvalvular hemodynamics and left ventricle reverse remodeling;During the average follow-up period, a significantly lower average pressure gradient and a higher effective opening area were recorded in the group undergoing neocuspidization with autologous pericardium compared to other types of implants;Despite the obvious hemodynamic advantages of transcatheter aortic valve replacement, the midterm follow-up has revealed significant residual aortic regurgitation, which is highly undesirable. AbstractCurrently, there are not enough data on the comparative analysis of echocardiographic outcomes, especially in regards to the state of the left ventricle in the long term after different aortic valve interventions. In this review, we present up-to-date literature data (publications published over 20 years) concerning echocardiographic outcomes after different aortic valve replacements. For the search of publications, the authors used international databases such as Scopus, Web of Science, Pubmed and Cochrane. The search keywords were: “aortic valve surgery”, “long-term period”, “echocardiographic outcomes”, “quality of life”. The analysis includes only comparative randomized, prospective or retrospective studies. A comparison between mechanical and biological prostheses has demonstrated that mechanical valves, in addition to displaying higher durability, can be advantageous in certain situations to bioprostheses in relation to transvalvular hemodynamics and reverse left ventricle remodeling. Regarding the comparison of stentless and stented bioprostheses with respect to peak transvalvular gradients and the effective orifice area, an obvious advantage was observed in the stentless bioprosthesis group. The majority of randomized clinical trials have showed great hemodynamic advantages of the Ross procedure in comparison with other types of aortic valve replacement, and an increase in the number of participants (due to future trials) may demonstrate even greater statistical significance. We have found only one publication that presents data on the comparison of the mid-term hemodynamic outcomes of neocuspidization of the aortic valve using autologous pericardium with other types of interventions. With an average follow-up period of 426±270 days, a significantly lower average pressure gradient and a higher effective orifice area were recorded in the neocuspidization group. Despite hemodynamic benefits of transcatheter aortic valve replacement in the mid-term period after surgery, the results of postoperative monitoring show significant residual aortic regurgitation, which is highly undesirable.","PeriodicalId":227108,"journal":{"name":"Complex Issues of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114537959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DIFFICULTY OF DIAGNOSING METASTATIC BREAST CANCER IN A PATIENT AFTER MINIMALLY INVASIVE AORTIC VALVE REPLACEMENT: A CLINICAL CASE","authors":"V. Evtushenko, Alexandra N. Zhilina, V. Saushkin, A. Evtushenko","doi":"10.17802/2306-1278-2023-12-2-138-143","DOIUrl":"https://doi.org/10.17802/2306-1278-2023-12-2-138-143","url":null,"abstract":"HighlightsThe article describes a clinical case of a patient with metastatic breast cancer detected after aortic valve replacement. The case was initially treated as sternal osteomyelitis due to ministernotomy performed during aortic valve surgery. However, the diagnosis of metastatic breast cancer with sternal and spinal (third thoracic vertebra) metastatses, and ribs lesion was established upon further study. Adjuvant endocrine therapy was prescribed to the patient due to her age and previous surgery. AbstractBreast cancer is an urgent problem in oncology as it remains the most frequent type of cancer in the Russian Federation and world wide. Long-term treatment success and survival of patients depend on selected treatment modality, and long-term postopertive monitoring of patients as the means of the early detection of metastatic recurrence. Furthermore, concominant somatic ilness could change or mask the symptoms of local recurrence or metastasis, resulting in difficulties with establishing the proper diagnosis. We report a clinical case of metastatic breast cancer in a patient with severe aortic stenosis who underwent aortic valve replacement. We have not found analogious cases in domestic and foreign literature.","PeriodicalId":227108,"journal":{"name":"Complex Issues of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128482600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}