The European Research Journal最新文献_第2页

Association of frailty with nutritional parameters in patients with chronic kidney disease 慢性肾病患者的虚弱程度与营养参数的关系

The European Research Journal Pub Date : 2024-03-17 DOI: 10.18621/eurj.1376545

Recep Evcen, M. Koçak, Rengin Elsürer Afşar

{"title":"Association of frailty with nutritional parameters in patients with chronic kidney disease","authors":"Recep Evcen, M. Koçak, Rengin Elsürer Afşar","doi":"10.18621/eurj.1376545","DOIUrl":"https://doi.org/10.18621/eurj.1376545","url":null,"abstract":"Objectives: Frailty is a significant clinical syndrome characterized by greater susceptibility to stressors due to the dysfunction of multiple organ systems, which increases in prevalence with age. This study was performed to investigate relations between frailty and nutritional parameters in patients with chronic kidney disease (CKD).\u0000Methods: This cross-sectional study involved 100 CKD patients aged 50 years or older. Frailty was assessed using the Edmonton Frailty Scale (EFS) and Fried’s Frailty Scale (FFS). The patients nutritional status was assessed using the Mini Nutritional Assessment (MNA) and the routine laboratory tests.\u0000Results: The study included 100 patients, consisting of 41 females and 59 males. The mean age of the participants was 65.3±9.3 years. The median glomerular filtration rate (GFR) of the patients was 23 mL/min/1.73 m2) (min: 3-max: 65). According to the MNA, 15 patients had normal nutritional status, 63 were at risk of malnutrition, and 22 were malnourished. According to the EFS score, four patients were categorized as not frail, 11 as vulnerable, 25 with mild frailty, 21 with moderate frailty, and 39 with severe frailty. According to the FFS score, six patients were non-frail, 30 were classified as pre-frail, and 64 were considered frail. \u0000Conclusions: Frailty and malnutrition in patients with CKD were independently related to all other factors examined in this study. Screening for malnutrition at the early stages in patients with CKD and the appropriate treatment may prevent the development of frailty.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"169 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140235868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The relationship between fibromyalgia syndrome and inflammation parameters in hemodialysis patients 血液透析患者纤维肌痛综合征与炎症参数之间的关系

The European Research Journal Pub Date : 2024-03-16 DOI: 10.18621/eurj.1361155

Semahat Karahisar Şirali, R. Büberci̇

{"title":"The relationship between fibromyalgia syndrome and inflammation parameters in hemodialysis patients","authors":"Semahat Karahisar Şirali, R. Büberci̇","doi":"10.18621/eurj.1361155","DOIUrl":"https://doi.org/10.18621/eurj.1361155","url":null,"abstract":"Objectives: Diagnosing fibromyalgia, a condition characterized by widespread body pain of unknown origin accompanied by various additional symptoms, poses a challenge in hemodialysis patients, who frequently experience musculoskeletal disorders. To investigate the relationship between fibromyalgia syndrome and inflammation parameters in hemodialysis patients.\u0000Methods: The study enrolled 311 hemodialysis patients undergoing treatment for over three months. Demographic characteristics, complete blood count, and biochemical values were documented as part of the study. To assess fibromyalgia, the researchers recorded the patients scores on the Generalized Pain Scale and Symptom Severity Scale based on data provided by the American College of Rheumatology. The patients were then divided into two groups: those with fibromyalgia and those without fibromyalgia, and their laboratory values and rates were compared. Inflammatory parameters such as erythrocyte sedimentation rate, c reactive protein, monocyte-to-lymphocyte ratio, lymphocyte-to-c reactive protein ratio, and c reactive protein to albumin ratio were recorded. \u0000Results: The study included 311 patients on hemodialysis for more than three months. Among the study participants, 48.9% of the patients and 62.9% of those with fibromyalgia were women. The mean age was 54±26 years and was significantly higher in patients with fibromyalgia (P<0.001). Monocyte (P<0.03), C-reactive protein (P<0.01), erythrocyte sedimentation rate (P<0.02), Monocyte to lymphocyte ratio (P=0.028), c reactive protein to albumin ratio (P<0.005) were significantly higher, lymphocyte to c reactive protein ratio (P<0.004) and albumin (P=0.018) were significantly lower in the fibromyalgia group.\u0000Conclusions: Fibromyalgia should be considered in the presence of high inflammation parameters in hemodialysis patients with diffuse musculoskeletal pain.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"62 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140237086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical excision of the right ventricular hydatid cyst: a case report 右心室包虫囊肿手术切除：病例报告

The European Research Journal Pub Date : 2024-02-02 DOI: 10.18621/eurj.1399415

M. Abanoz, Mehmet Yazar, S. Talay, Candan Mansuroglu

引用次数: 0

Solitary myofibroma in children: a report of two cases 儿童单发肌纤维瘤：两个病例的报告

The European Research Journal Pub Date : 2024-01-01 DOI: 10.18621/eurj.1382704

Çağrı Coşkun, K. Kösemehmetoğlu, Mehmet Ayvaz, Ibrahim Vargel, Ü. Aydıngöz, H. Özcan, A. Varan, B. Yalçın

引用次数: 0

Secondary iatrogenic duedonum perforation: a rare complication 继发性先天性十二指肠穿孔：一种罕见的并发症

The European Research Journal Pub Date : 2023-12-31 DOI: 10.18621/eurj.1356093

Alperen Özdoğan, O. Ay, İsmail Yilmaz

引用次数: 0

Relationship of breast arterial calcification and radiotherapy 乳腺动脉钙化与放疗的关系

The European Research Journal Pub Date : 2023-12-29 DOI: 10.18621/eurj.1382545

Gökhan Karataş, Osman Kula, N. Tunçbilek

引用次数: 0

Predictive value of NLRC3 levels for pulmonary hypertension in patients with chronic obstructive pulmonary disease NLRC3 水平对慢性阻塞性肺病患者肺动脉高压的预测价值

The European Research Journal Pub Date : 2023-12-28 DOI: 10.18621/eurj.1357708

Meltem Yilmaz, L. Mutlu, Şeref Alpsoy, Aydın Akyüz, A. Çelikkol, Özlem Kaymaz

{"title":"Predictive value of NLRC3 levels for pulmonary hypertension in patients with chronic obstructive pulmonary disease","authors":"Meltem Yilmaz, L. Mutlu, Şeref Alpsoy, Aydın Akyüz, A. Çelikkol, Özlem Kaymaz","doi":"10.18621/eurj.1357708","DOIUrl":"https://doi.org/10.18621/eurj.1357708","url":null,"abstract":"Objectives: Chronic obstructive pulmonary disease (COPD) is a medical condition defined by persistent airflow limitation and respiratory symptoms caused by airway and/or alveolar abnormalities. Pulmonary hypertension (PH) is one of the cardiovascular comorbidities associated with COPD. We investigated the correlation of NLRC3 levels in patients with COPD with prognostic and surrogate parameters of PH on echocardiography and examined whether it could be used to predict PH in this patient population. Methods: A total of 80 patients diagnosed with COPD and 40 healthy volunteers as the control group were included in the study. The COPD group was further divided into two subgroups according to the systolic pulmonary artery pressure (sPAP) as follows: sPAP<35 mmHg and sPAP≥35 mmHg. The enzyme-linked immunosorbent assay (ELISA) method was used to determine the levels of NLRC3 in peripheral blood. Results: Patients with sPAP≥35 mmHg had a lower mean NLRC3 level than those with sPAP<35 mmHg (P=0.006). The NLRC3 levels showed a significant negative correlation with sPAP, tricuspid regurgitation velocity, right atrium, and pulmonary artery diameter. For NLRC3, the cut-off value was found to be 271,486 ng/L, with a sensitivity of 74%, and specificity of 63% in distinguishing patients with sPAP≥35 mmHg from all patients with sPAP<35 mmHg. Conclusions: Our study results suggest that NLRC3 levels measured from peripheral blood are predictive of PH in patients with COPD. Although the exact function of NLRC3 in the lungs, COPD, and PH have not been completely understood, we believe these findings will serve as a model for future studies.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"239 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139152802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The relationship between heart functions and anemia in patients with end-stage renal disease receiving hemodialysis 接受血液透析的终末期肾病患者的心脏功能与贫血之间的关系

The European Research Journal Pub Date : 2023-12-26 DOI: 10.18621/eurj.1401607

T. Omar, Metin Çağdaş, I. Artac, M. Karakayalı, Dogan Ilis, Ayça Arslan, Y. Karabağ, M. Yesin, Mustafa Avci, I. Rencüzoğulları

{"title":"The relationship between heart functions and anemia in patients with end-stage renal disease receiving hemodialysis","authors":"T. Omar, Metin Çağdaş, I. Artac, M. Karakayalı, Dogan Ilis, Ayça Arslan, Y. Karabağ, M. Yesin, Mustafa Avci, I. Rencüzoğulları","doi":"10.18621/eurj.1401607","DOIUrl":"https://doi.org/10.18621/eurj.1401607","url":null,"abstract":"Objective: We investigated the relationship between anemia and cardiac functions by conventional and speckle-tracking echocardiography (STE) in patients with end-stage renal disease (ESRD) receiving hemodialysis. Methods: One hundred six patients with ESRD receiving hemodialysis were included in this cross-sectional study. The conventional echocardiography and STE findings were compared between the patients with and without anemia. In addition, a comparison of the findings between the ESRD patients and healthy controls consisting of 68 participants was conducted. Results: Compared to healthy controls, ESRD patients had lower left ventricular ejection fraction (LVEF), left ventricular global longitudinal strain (LVGLS), and left atrial reservoir strain (LASr) [53% (48-57) vs. 65% (62-68), -15.2 (-16.9˗ -13.6) vs. -19.7 (-16.9˗ -13.6), and -21.9 (-29.5˗ -15.3) vs. -29.9 (-35.3˗ -22.8), respectively, P-value <0.001 for all]. Of the ESRD patients, 70 (66%) had anemia. ESRD patients with anemia had higher interventricular septum (IVS), posterior wall (PW), and left atrial volume index (LAVi) values than patients without anemia. In addition, ESRD patients with anemia had lower LVEF, LVGLS, and LASr than patients without anemia [median (IQR), 13 (12-15) vs. 12 (11-14), P=0.004, 13 (12-15) vs. 12 (11-13.5), P<0.005, 43 (35-55) vs. 34.7 (28-50), P=0.013, 52 (48-55) vs. 56 (47.5-60), P=0.016, -14.6 (-16.4˗ -13.5) vs. -16 (-18.6˗ -14.7), P=0.003, and -21.6 (-30.5˗ -16.3) vs. -30.5 (-33.6˗ -23.3), P=0.006, respectively]. In multivariable logistic regression analysis, diabetes, PW, LASr, and LVGLS were independently associated with the presence of anemia in ESRD patients. Conclusion: Our study confirmed impaired cardiac mechanics in ESRD hemodialysis patients and showed that anemia was associated with further worsening cardiac mechanics in this population.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"20 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139155318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The protective and antiapoptotic effects of Hypericum triquetrifolium Turra against cyclophosphamide-induced lung injury in rats: in vitro evaluation 三棱金丝桃对环磷酰胺诱导的大鼠肺损伤的保护和抗凋亡作用：体外评估

The European Research Journal Pub Date : 2023-12-22 DOI: 10.18621/eurj.1373134

Songul Cetik Yildiz, C. Keskin, V. Şahintürk, Adnan Ayhanci

{"title":"The protective and antiapoptotic effects of Hypericum triquetrifolium Turra against cyclophosphamide-induced lung injury in rats: in vitro evaluation","authors":"Songul Cetik Yildiz, C. Keskin, V. Şahintürk, Adnan Ayhanci","doi":"10.18621/eurj.1373134","DOIUrl":"https://doi.org/10.18621/eurj.1373134","url":null,"abstract":"Objectives: Hypericum triquetrifolium Turra (HTT) has been traditionally used in medical treatments due to its sedative, antiseptic, antiinflammatory, and anthelmintic properties. The present study aims to investigate the lung-protective and antiapoptotic effects of HTT against cyclophosphamide (CP)-induced lung injury in rats. Methods: Thirty-five Sprague Dawley rats were categorized into 5 groups, each consisting of seven members. Phenolic acid and flavonoid contents of this plant were determined. The lung tissue samples cultivated from the rats were examined in histopathological and immunohistochemically for the apoptosis markers of Caspase-3, Bax, and Bcl-2. Results: Histopathological results indicated that structural defects, bleeding areas, and edema had occurred in the lungs of the CP-Alone Group. Besides, Caspase-3 and Bax positivity of the lung cells had also increased while Bcl-2 positivity had decreased. On the other hand, in the HTT+CP Group, HTT was shown to have reversed the aforementioned changes positively. Conclusion: Based on in vivo results, HTT could be a strong protective candidate for CP-induced lung injury and apoptosis","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"48 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139164272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictive value of ACEF score for acute kidney injury after surgical aortic valve replacement 手术主动脉瓣置换术后急性肾损伤的 ACEF 评分预测价值

The European Research Journal Pub Date : 2023-12-21 DOI: 10.18621/eurj.1334048

Gokhan Demirci, A. R. Demir, Serkan Kahraman, S. Çamcı, Emre Yilmaz

{"title":"Predictive value of ACEF score for acute kidney injury after surgical aortic valve replacement","authors":"Gokhan Demirci, A. R. Demir, Serkan Kahraman, S. Çamcı, Emre Yilmaz","doi":"10.18621/eurj.1334048","DOIUrl":"https://doi.org/10.18621/eurj.1334048","url":null,"abstract":"Objectives: Aortic stenosis is the most common form of degenerative heart valve disease. Acute kidney injury (AKI) after aortic valve replacement (AVR) is a common complication and is related to worse outcomes. Age, creatinine, and ejection fraction (ACEF) score is a simple scoring method that includes three parameters. Our study aimed to evaluate whether ACEF score could predict the development of AKI in patients who underwent AVR.\u0000Methods: A total of 366 consecutive patients who underwent isolated AVR for symptomatic severe aortic stenosis were evaluated retrospectively. The development of AKI was the primary endpoint of the study. The ACEF score was calculated by the formula: age (years)/left ventricular ejection fraction (%) + 1 (if baseline serum creatinine was >2 mg/dL). According to the ACEF score the study population was divided into two groups.\u0000Results: AKI was developed in 66 (18%) patients. The cut-off value of the ACEF score for the prediction of AKI was 1.07 with a sensitivity of 69.7% and a specificity of 56.7% (AUC 0.663; 95% CI: 0.589-0.736; P<0.001). AKI incidence was found to be higher in patients with high ACEF score than low ACEF score [46 (26.1%) vs. 20 (10.5%); P<0.001]. In addition, ACEF score [OR: 2.599; 95% CI: 1.399-4.828; P=0.002] and hemoglobin levels (OR: 0.837; 95% CI: 0.729-0.961; P=0.012) were found to be independent predictors of AKI. \u0000Conclusions: Our study revealed that the ACEF score is an independent predictor of AKI. ACEF score, as a simple and objective score, can be useful in predicting AKI in patients undergoing AVR.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"27 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138952295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0