The Chinese Journal of Modern Applied Pharmacy最新文献

筛选

英文中文

Purification of Z-Ligustilide by AgNO_3-Impregnated Silica Gel agno_3浸渍硅胶纯化z -藁本内酯

The Chinese Journal of Modern Applied Pharmacy Pub Date : 2014-01-01 DOI: 10.13748/J.CNKI.ISSN1007-7693.2014.05.009

Yuan-yuan Cheng, C. Yang, J. Zhao, J. Rong

{"title":"Purification of Z-Ligustilide by AgNO_3-Impregnated Silica Gel","authors":"Yuan-yuan Cheng, C. Yang, J. Zhao, J. Rong","doi":"10.13748/J.CNKI.ISSN1007-7693.2014.05.009","DOIUrl":"https://doi.org/10.13748/J.CNKI.ISSN1007-7693.2014.05.009","url":null,"abstract":"OBJECTIVE To investigate the application of AgNO 3 -impregnated silica gel in a format of column chromatography for the isolation and purification of Z-ligustilide from the essential oil of Ligusticum chuanxiong Hort.. METHODS AgNO 3 (2%) was impregnated to the common silica gel to generate a new column chromatographic media. The essential oil was eluted with the mobile phase (petroleum ether: acetoacetate=98.5 1.5), and detected by TLC and UV-Vis spectrometer. The product Z-ligustilide was characterized by GC-MS and HPLC techniques. RESULTS Z-Ligustilide with the purity of 98.87% was effectively purified. CONCLUSION The present study describes a method for rapid isolation of highly pure Z-ligustilide at low cost, allowing future scale-up for modern industrial production. KEY WORDS: Z-ligustilide; AgNO 3 -silica gel; isolation and purification; GC-MS; HPLC Tel: (852)64870314 E-mail: sxucerycery@126.com * Tel: (852)62265496 E-mail: jrong@hku.hk (Ligusticum chuanxiong Hort.) !\"#$% &'()* +,-./0 1 23456 78 9 : ;<=>?@ABCD AE FG@\"H IJKLMNOPQR [1-2] #ST +,UV WXYZ[]A COX-2 )^_`a PGE-2 bc d efghijhk^lm \" [3-4] # nopq +, rst uvM -H I23E wxyZ[z{!UVWXY ROSbc>h MAPK NF-κB AP-1|}V~ F [5] \u0085VW PI3K> Nrf2V~ EEQv z{ [6-7] #n opq 1#'()* nopq; TU:u78Q HI L Q [8] # nopq X¡>¢ £¤ U K?@¥¦§ ̈ ©Jaf «¬h®![9] #̄ °±23 +, ́ GC-MSMμ ¶$· ̧ 1 80o»1⁄4vM 1⁄23⁄4 ¿ÀÁÂÀÁÃÀÄÅpqÁnopqÁ p q A ® [10] #ST +, nopq> pq A ÆÇÃÀÄÅpq ÈÉ vÊ Ë ÌÍÎÏÐMÑJÒÓnopq ÔÕ#","PeriodicalId":22401,"journal":{"name":"The Chinese Journal of Modern Applied Pharmacy","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81529443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Chemical constituents from the fruit of Schisandra Chinensis 五味子果实的化学成分

The Chinese Journal of Modern Applied Pharmacy Pub Date : 2006-01-01 DOI: 10.5246/jcps.2020.07.045

Wang Li-wei, Zhou Changxin

引用次数: 3