The Chemical Educator最新文献

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Investigating the Seed-Growth Method for the Synthesis of Silver Sols with Several Colors 种子生长法合成多色银溶胶的研究
The Chemical Educator Pub Date : 2018-03-01 DOI: 10.1333/S00897182788A
Ignace De Coninck, Dries Curvers, Natalie Chiaverini, Tom Mortier
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引用次数: 0
A Low-Cost Method for Measuring the Permeability of a Pharmaceutical Drug in a Diffusion Cell 一种在扩散池中测量药物渗透性的低成本方法
The Chemical Educator Pub Date : 2014-01-01 DOI: 10.1333/S00897142584A
Megan Kitson, Heather N. Sheppard, Joanne C. Morris, N. Howarth, A. Kraft
{"title":"A Low-Cost Method for Measuring the Permeability of a Pharmaceutical Drug in a Diffusion Cell","authors":"Megan Kitson, Heather N. Sheppard, Joanne C. Morris, N. Howarth, A. Kraft","doi":"10.1333/S00897142584A","DOIUrl":"https://doi.org/10.1333/S00897142584A","url":null,"abstract":"A low-cost, in vitro laboratory experiment has been developed that mimics the absorption of a pharmaceutical drug in the body. It allows undergraduate chemistry students to gain experience in the measurement of drug permeability coefficients, a key indicator used by the pharmaceutical industry to identify the ease of absorption of any new drug candidate. The experiment requires a diffusion cell, coated membrane, peristaltic pump and UV-Vis spectrophotometer. The method has been validated by determining the permeability coefficients for a selection of acidic, basic and non-ionizable drugs. Using this assay, it is possible to classify drugs as exhibiting high or low permeability in a fast, facile and reliable manner.","PeriodicalId":22396,"journal":{"name":"The Chemical Educator","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84921827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Less Cookbook and More Research! Synthetic Efforts Toward JBIR-94 and JBIR-125: a Student-Designed Research Project in a Sophomore Organic Chemistry Lab 少写食谱,多做研究!合成JBIR-94和JBIR-125的努力:二年级有机化学实验室学生设计的研究项目
The Chemical Educator Pub Date : 2014-01-01 DOI: 10.1007/S00897132528A
M. A. Christiansen, C. L. Crawford, C. D. Mangum
{"title":"Less Cookbook and More Research! Synthetic Efforts Toward JBIR-94 and JBIR-125: a Student-Designed Research Project in a Sophomore Organic Chemistry Lab","authors":"M. A. Christiansen, C. L. Crawford, C. D. Mangum","doi":"10.1007/S00897132528A","DOIUrl":"https://doi.org/10.1007/S00897132528A","url":null,"abstract":"","PeriodicalId":22396,"journal":{"name":"The Chemical Educator","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75863277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Modeling chemical kinetics graphically 化学动力学图形化建模
The Chemical Educator Pub Date : 2012-01-01 DOI: 10.1007/S00897122435
A. Heck
{"title":"Modeling chemical kinetics graphically","authors":"A. Heck","doi":"10.1007/S00897122435","DOIUrl":"https://doi.org/10.1007/S00897122435","url":null,"abstract":"","PeriodicalId":22396,"journal":{"name":"The Chemical Educator","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89861233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Getting a Head Start: The Benefits of Starting Undergraduate Research as a Freshman 获得一个良好的开端:作为一名新生开始本科研究的好处
The Chemical Educator Pub Date : 2012-01-01 DOI: 10.1007/S00897122451
Stephen J. Crooke, C. M. McGibony, C. Whitlock
{"title":"Getting a Head Start: The Benefits of Starting Undergraduate Research as a Freshman","authors":"Stephen J. Crooke, C. M. McGibony, C. Whitlock","doi":"10.1007/S00897122451","DOIUrl":"https://doi.org/10.1007/S00897122451","url":null,"abstract":"","PeriodicalId":22396,"journal":{"name":"The Chemical Educator","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86663557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blue Bottle Light Experiments for Demonstrating Basic Kinetics Features of Homogeneous and Heterogeneous Photoinduced Redox Reactions 证明均相和非均相光诱导氧化还原反应基本动力学特征的蓝瓶光实验
The Chemical Educator Pub Date : 2010-03-03 DOI: 10.1333/S00897102267A
A. Mills, D. Macphee, K. Lawrie
{"title":"Blue Bottle Light Experiments for Demonstrating Basic Kinetics Features of Homogeneous and Heterogeneous Photoinduced Redox Reactions","authors":"A. Mills, D. Macphee, K. Lawrie","doi":"10.1333/S00897102267A","DOIUrl":"https://doi.org/10.1333/S00897102267A","url":null,"abstract":"","PeriodicalId":22396,"journal":{"name":"The Chemical Educator","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86838991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isomerization kinetics of potassium diaquobis(oxalato)chromate(III) 二水合(草酸)铬酸钾(III)的异构化动力学
The Chemical Educator Pub Date : 2010-01-01 DOI: 10.1007/S00897102329A
João C. Sotomayor
{"title":"Isomerization kinetics of potassium diaquobis(oxalato)chromate(III)","authors":"João C. Sotomayor","doi":"10.1007/S00897102329A","DOIUrl":"https://doi.org/10.1007/S00897102329A","url":null,"abstract":"","PeriodicalId":22396,"journal":{"name":"The Chemical Educator","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75755636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Jigsaw Exercise in the Organic Classroom 有机课堂中的拼图游戏
The Chemical Educator Pub Date : 2009-01-01 DOI: 10.1333/S00897092200A
C. Whitlock
{"title":"A Jigsaw Exercise in the Organic Classroom","authors":"C. Whitlock","doi":"10.1333/S00897092200A","DOIUrl":"https://doi.org/10.1333/S00897092200A","url":null,"abstract":"","PeriodicalId":22396,"journal":{"name":"The Chemical Educator","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77306673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Conversion of urea to hydrazine: Hofmann reaction or Favorskii analogue? Exploring reaction mechanism through isotopic labeling studies 尿素转化为肼:Hofmann反应还是Favorskii类似物?通过同位素标记研究探索反应机理
The Chemical Educator Pub Date : 2007-10-01 DOI: 10.1333/S00897072074A
P. S. Francis, K. Lim
{"title":"Conversion of urea to hydrazine: Hofmann reaction or Favorskii analogue? Exploring reaction mechanism through isotopic labeling studies","authors":"P. S. Francis, K. Lim","doi":"10.1333/S00897072074A","DOIUrl":"https://doi.org/10.1333/S00897072074A","url":null,"abstract":"The power of isotopic substitution for the elucidation of a reaction mechanism is illustrated with reactions named after Hofmann and Favorskii. These reactions have important roles in synthetic chemistry; therefore, a wide range of experiments involving isotopic labeling or kinetic isotope effects were employed to establish their mechanistic pathways. The concepts introduced by these investigations are drawn together with an isotopic labeling study of the oxidation of urea with hypohalites. The two mechanisms proposed for this reaction have been described as a Hofmann rearrangement and a nitrogen analogue of the Favorskii rearrangement.","PeriodicalId":22396,"journal":{"name":"The Chemical Educator","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86149468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The National Atmospheric Deposition Program (NADP): Measuring the Chemistry of the Earth’s Atmosphere and Its Applications for the First-Year Chemistry Classroom 国家大气沉积计划(NADP):地球大气化学的测量及其在一年级化学课堂上的应用
The Chemical Educator Pub Date : 2006-01-01 DOI: 10.1333/S00897061065A
Christopher Lehmann
{"title":"The National Atmospheric Deposition Program (NADP): Measuring the Chemistry of the Earth’s Atmosphere and Its Applications for the First-Year Chemistry Classroom","authors":"Christopher Lehmann","doi":"10.1333/S00897061065A","DOIUrl":"https://doi.org/10.1333/S00897061065A","url":null,"abstract":"","PeriodicalId":22396,"journal":{"name":"The Chemical Educator","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79932436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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