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Ross River virus infection of human synovial cells in vitro. 罗斯河病毒体外感染人滑膜细胞的研究。
The Australian journal of experimental biology and medical science Pub Date : 1985-04-01
A L Cunningham, J R Fraser
{"title":"Ross River virus infection of human synovial cells in vitro.","authors":"A L Cunningham,&nbsp;J R Fraser","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ross River virus (RRV) strains T48 and SC18006 produced a self-limited cytopathic infection of primary and passaged human synovial cell culture. Extracellular (EC) virus titres reached peak levels at 2 days in cell lines and at 4 days in primary cultures, ranging between 10(4.5) and 10(6.6) fluorescent focus-forming units (ffu)/ml. Thereafter titres declined rapidly to undetectable levels at 10-12 days. The proportion of adherent cells showing virus antigen exceeded 60% at 3 days and decreased in all cultures to less than 1/500 after 12 days. Cytopathic effects (CPE) were greatest at 4-8 days and destroyed between 25 and 75% of the cell layer, with subsequent partial regeneration by division of surviving cells. In contrast to rubella virus infection of synovial cells, cultures at 32 degrees and 37 degrees revealed only minor differences and persistent infection was not established. CPE were more extensive at 37 degrees in nearly all synovial cell cultures and in Vero cultures. At 37 degrees synovial cells infected with T48 strain produced higher maximum titres and were more extensively infected than at 32 degrees.</p>","PeriodicalId":22318,"journal":{"name":"The Australian journal of experimental biology and medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14129602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vitro enhancement of the helminthotoxic capacity of human blood eosinophils. 体外增强人血嗜酸性粒细胞的蠕虫毒能力。
The Australian journal of experimental biology and medical science Pub Date : 1981-12-01
M A Vadas, A Dessein, N Nicola, J R David
{"title":"In vitro enhancement of the helminthotoxic capacity of human blood eosinophils.","authors":"M A Vadas,&nbsp;A Dessein,&nbsp;N Nicola,&nbsp;J R David","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22318,"journal":{"name":"The Australian journal of experimental biology and medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17218802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pyrimidine and purine enzymes in Toxoplasma gondii. 刚地弓形虫的嘧啶和嘌呤酶。
The Australian journal of experimental biology and medical science Pub Date : 1981-12-01
W J O'Sullivan, A M Johnson, K G Finney, A M Gero, E Hagon, J W Holland, G W Smithers
{"title":"Pyrimidine and purine enzymes in Toxoplasma gondii.","authors":"W J O'Sullivan,&nbsp;A M Johnson,&nbsp;K G Finney,&nbsp;A M Gero,&nbsp;E Hagon,&nbsp;J W Holland,&nbsp;G W Smithers","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22318,"journal":{"name":"The Australian journal of experimental biology and medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17188663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of organ culture on function of transplanted foetal pancreas. 器官培养对移植胎儿胰腺功能的影响。
The Australian journal of experimental biology and medical science Pub Date : 1981-12-01
C J Simeonovic, K J Lafferty
{"title":"Effect of organ culture on function of transplanted foetal pancreas.","authors":"C J Simeonovic,&nbsp;K J Lafferty","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22318,"journal":{"name":"The Australian journal of experimental biology and medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17856316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumor immunity to murine plasma cell tumours. Influence of responder genotype on the specificity of the immune response to plasmacytomas and T lymphomas. 小鼠浆细胞瘤的肿瘤免疫。应答者基因型对浆细胞瘤和T淋巴瘤免疫应答特异性的影响。
The Australian journal of experimental biology and medical science Pub Date : 1978-10-01
R C Burton, N L Warner
{"title":"Tumor immunity to murine plasma cell tumours. Influence of responder genotype on the specificity of the immune response to plasmacytomas and T lymphomas.","authors":"R C Burton,&nbsp;N L Warner","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A tumour-associated antigen has been identified which is expressed on both BALB/c plasmacytomas and T lymphomas, but which does not induce a detectable cell-mediated immune response in the strain of origin of the tumours. The (BALB/c x C57BL) F1 hybrid, however, makes a readily detectable response both in vivo and in vitro in vitro experiments with various BALB/c H-2 F1 cogenic mice indicated that the genetic control of the response was not H-2 linked, and was associated with other C57BL genes.</p>","PeriodicalId":22318,"journal":{"name":"The Australian journal of experimental biology and medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11950952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Haemoglobins in cattle and buffalo. Haemoglobin types of Bos taurus, Bos indicus, Bos banteng and Bubalis bubalis in northern Australia. 牛和水牛的血红蛋白。澳大利亚北部牛牛、印度牛、班腾牛和布巴利牛的血红蛋白类型。
The Australian journal of experimental biology and medical science Pub Date : 1978-10-01
A W Bachmann, R S Campbell, D Yellowlees
{"title":"Haemoglobins in cattle and buffalo. Haemoglobin types of Bos taurus, Bos indicus, Bos banteng and Bubalis bubalis in northern Australia.","authors":"A W Bachmann,&nbsp;R S Campbell,&nbsp;D Yellowlees","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The frequency of haemoglobin types in several major breeds of cattle in northern Austrailia was determined. In all Boss taurus cattle examined only the three common bovine haemoglobin types (AA, AB, BB) were found. F2 Africander cross-breeds showed only AA patterns. The frequency of haemoglobin B was significantly higher in Bos indicus type cattle than in Bos taurus breeds. In the pure breed Banteng cattle (Bos banteng) three genotypes (BB, CB, CC) were present. The eleven buffaloes types each showed two haemoglobins (A1 and A2) in proporotions of 71 to 29 respectively.</p>","PeriodicalId":22318,"journal":{"name":"The Australian journal of experimental biology and medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11950951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Obituary. Mark Ledingham Mitchell. 讣告。Mark Ledingham Mitchell。
The Australian journal of experimental biology and medical science Pub Date : 1978-08-01
{"title":"Obituary. Mark Ledingham Mitchell.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22318,"journal":{"name":"The Australian journal of experimental biology and medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11573400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rodent zoonoses in North Queensland: the occurrence and distribution of zoonotic infections in North Queensland rodents. 北昆士兰鼠类人畜共患病:北昆士兰鼠类人畜共患病的发生和分布。
The Australian journal of experimental biology and medical science Pub Date : 1978-04-01
J S Glazebrook, R S Campbell, G W Hutchinson, N D Stallman
{"title":"Rodent zoonoses in North Queensland: the occurrence and distribution of zoonotic infections in North Queensland rodents.","authors":"J S Glazebrook,&nbsp;R S Campbell,&nbsp;G W Hutchinson,&nbsp;N D Stallman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A study of potentially zoonotic infections was carried out on 351 rodents trapped in north-eastern Queensland. Their ecosystems included towns, agricultural and livestock areas, wookland and rainforest. Nine serotypes of salmonellae were obtained from asymptomatic carries in predominantly settled locations. Two strains of Ps. pseudomallei occurred in rainforest near Innisfail and one on a cattle property adjacent to Townsville. Ps. aeruginosa caused bronchopneumonia in one animal from Townsville harbour. Ifection by leptospirae of six serogroups and seven serovars were identified by serological or cultural examinations. Enzootic foci occurred on the Mount Spec rainforest where celledoni and australis were being excreted by rats adjacent to the Paluma dam system. In addition to the scrub typhus locations at Rocky Creek, Atherton Tableland and Bullocky Creek, near Ingham, which were confirmed, a new focus of infection by R. tsutsugamushi was identified at El Arish near Tully. Water rat (H. chrysogaster) at Townsville harbour constituted a reservoir of toxoplasmosis. In addition to the known human pathogenic helminths H. nana and H. diminuta, localized foci of hookworms (Ancylostoma spp.) were found. Histological evidence of cytomegalic disease of the salivary glands or kidneys was a common finding.</p>","PeriodicalId":22318,"journal":{"name":"The Australian journal of experimental biology and medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11880133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Macrophages and resistance to tumours: influence of agents affecting macrophages and delayed-type hypersensitivity on resistance to tumours inducing concomitant immunity. 巨噬细胞和肿瘤抵抗:影响巨噬细胞和延迟型超敏反应的药物对肿瘤诱导伴随免疫抵抗的影响
The Australian journal of experimental biology and medical science Pub Date : 1978-04-01
M Nelson, D S Nelson
{"title":"Macrophages and resistance to tumours: influence of agents affecting macrophages and delayed-type hypersensitivity on resistance to tumours inducing concomitant immunity.","authors":"M Nelson,&nbsp;D S Nelson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Early, specific concomitant immunity to each of four tumours was inhibited by treatment with silica or carrageenan. Late, non-specific concomitant immunity was, with one exception, not inhibited by these agents. Treatment of non-immune mice with silica at certain critical periods before challenge promoted the growth of four of six syngeneic methylcholanthrene-induced tumours in their feet. Treatment with carrageenan was much less effective. Early and late concomitant immunity were inhibited by one or more agents inhibiting delayed-type hypersensitivity: irradiation, niridazole and reserpine. Irradiation of non-immune mice did not effect the growth of tumours in their feet. Treatment of non-immune mice with niridazole or reserpine actually inhibited the growth of some tumours. It is suggested that (a) mice offer some natural resistance to tumour growth, macrophages perhaps being effectors; (b) some tumour isografts may survive only if an inflammatory reaction occurs; (c) mechanisms akin to those of delayed-type hypersensitivity operate in the expression of concomitant immunity; (d) macrophages are important in early, specific concomitant immunity, but perhaps less so in the late non-specific phase.</p>","PeriodicalId":22318,"journal":{"name":"The Australian journal of experimental biology and medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11425444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The ecology of influenza. Isolation of type 'A' influenza viruses from Australian pelagic birds. 流感的生态学。从澳大利亚远洋鸟类中分离A型流感病毒。
The Australian journal of experimental biology and medical science Pub Date : 1977-12-01
J C Downie, V Hinshaw, W G Laver
{"title":"The ecology of influenza. Isolation of type 'A' influenza viruses from Australian pelagic birds.","authors":"J C Downie,&nbsp;V Hinshaw,&nbsp;W G Laver","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Three different type A influenza viruses have been isolated from pelagic birds nesting on islands of the Great Barrier Reef. One of these, isolated in 1972, was of subtype Hav6Nav5. The other two, which are described in this paper, were isolated in 1975 and belonged to subtypes Hav5Nav2 and Hav3Nav6. Of eight isolates of the latter virus, seven were recovered from cloacal swabs and only one from the trachea.</p>","PeriodicalId":22318,"journal":{"name":"The Australian journal of experimental biology and medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11818012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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