G E Robinson, G S Underhill, G E Forster, C Kennedy, K McLean
{"title":"Treatment with acyclovir of genital herpes simplex virus infection complicated by eczema herpeticum.","authors":"G E Robinson, G S Underhill, G E Forster, C Kennedy, K McLean","doi":"10.1136/sti.60.4.241","DOIUrl":"https://doi.org/10.1136/sti.60.4.241","url":null,"abstract":"Eczema herpeticum is a potentially serious disease that may be fatal. We report two cases of infection with genital herpes simplex virus (HSV) that were complicated by eczema herpeticum and were treated successfully with acyclovir.","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 4","pages":"241-2"},"PeriodicalIF":0.0,"publicationDate":"1984-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.4.241","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17797157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of amoxycillin and procaine penicillin in the treatment of uncomplicated gonorrhoea.","authors":"J A Apaya","doi":"10.1136/sti.60.4.274-a","DOIUrl":"https://doi.org/10.1136/sti.60.4.274-a","url":null,"abstract":"","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 4","pages":"274-5"},"PeriodicalIF":0.0,"publicationDate":"1984-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.4.274-a","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17797160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Higher incidence of asymptomatic gonorrhoea in men with initial infection than with reinfection.","authors":"G Kavli, K M Saetrom, T Gundersen, G Volden","doi":"10.1136/sti.60.4.274","DOIUrl":"https://doi.org/10.1136/sti.60.4.274","url":null,"abstract":"","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 4","pages":"274"},"PeriodicalIF":0.0,"publicationDate":"1984-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.4.274","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17797159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MSSVD: secretary's report to the 62nd annual general meeting, 1983","authors":"M. Waugh","doi":"10.1136/STI.60.4.273","DOIUrl":"https://doi.org/10.1136/STI.60.4.273","url":null,"abstract":"","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"37 1","pages":"273 - 273"},"PeriodicalIF":0.0,"publicationDate":"1984-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88862251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case reports of urethritis","authors":"D. Taylor-Robinson, P. Furr, A. Webster","doi":"10.1136/sti.60.4.276-a","DOIUrl":"https://doi.org/10.1136/sti.60.4.276-a","url":null,"abstract":"Sir, Recent studies of anaerobic bacteria in both the male and female genital tracts have included techniques for the isolation of Clostridium difficile. 1-3 Hafiz et al isolated Cl difficile from 71 of vaginal specimens from patients attending a sexually transmitted disease (STD) clinic and 18% of women attending a family planning clinic, and from all of 42 men with non-specific urethritis (NSU).4 The results of more recent studies have been contradictory. Cl difficile was isolated from only two out of 79 patients with balanoposthitis, and not at all from 24 men with NSU, 19 men with both NSU and balanoposthitis, or from 28 asymptomatic controls.2 Moreover, Moss failed to isolate Cl difficile from 20 men and 34 women attending an STD clinic. A vaginal carriage rate of I% in consecutive female patients attending an STD clinic and 1807 in pregnant women was reported by O'Farrell et al using a selective broth medium.3 In this laboratory 206 vaginal swabs from 187 women, and urethral swabs from 20 men attending a special clinic were examined for Cl difficile. Swabs were broken off into cooked meat broth and incubated at 370C for five days before subculture on to modified CCFA medium,5 6 but Cl difficile was not isolated from any specimen. There exists an apparent dichotomy between the high carriage rates observed in both symptomatic and asymptomatic populations,3 4 and the negligible isolation rates encountered in this and other laboratories.1 2 This discrepancy might be explained by the use of isolation techniques of differing sensitivities, but the methods of Mossl and Masfari et a12 were essentially similar to those employed by Hafiz et al,4 and all recent investigations including the present one used enrichment culture and a highly efficient selective medium. The existence of a geographical variation in urogenital carriage of Cl difficile remains a possibility and requires further study.","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"180 ","pages":"276 - 277"},"PeriodicalIF":0.0,"publicationDate":"1984-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72554595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R F DiGiacomo, S A Lukehart, C D Talburt, S A Baker-Zander, J Condon, C W Brown
{"title":"Clinical course and treatment of venereal spirochaetosis in New Zealand white rabbits.","authors":"R F DiGiacomo, S A Lukehart, C D Talburt, S A Baker-Zander, J Condon, C W Brown","doi":"10.1136/sti.60.4.214","DOIUrl":"https://doi.org/10.1136/sti.60.4.214","url":null,"abstract":"<p><p>Ten sporadic cases of venereal spirochaetosis, caused by Treponema paraluis-cuniculi, were seen in New Zealand white rabbits in two years. An equal number of males and females were affected. Females tended to have milder clinical signs than males. Lesions were usually found on the prepuce in males and the vulva in females, although the anus and skin of the perineum were also affected. Facial lesions were rare. Lesions healed in seven to 28 days in rabbits treated with penicillin. Eight rabbits had antibodies reactive in the Venereal Disease Research Laboratory (VDRL), rapid plasma reagin (RPR), and fluorescent treponemal antibody absorbed (FTA-ABS) tests when the disease was first diagnosed. In several rabbits followed longitudinally, RPR test results became negative two to four months after antimicrobial treatment, VDRL antibody titres diminished but usually persisted at low levels, while FTA-ABS antibodies declined slowly and were still evident 12 months after treatment.</p>","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 4","pages":"214-8"},"PeriodicalIF":0.0,"publicationDate":"1984-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.4.214","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17603758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epstein-Barr (EB) virus infection in homosexual men in London.","authors":"D H Crawford, I Weller, V Iliescu, D W Wara","doi":"10.1136/sti.60.4.258","DOIUrl":"https://doi.org/10.1136/sti.60.4.258","url":null,"abstract":"<p><p>Twenty five homosexual men from London, 14 of whom had persistent lymphadenopathy and 11 of whom did not, were tested for immunity to Epstein-Barr (EB) virus. All yielded positive results to serological tests for the viral capsid antibody, and 11 had antibodies to the early antigen. Thirteen out of 17 were excreting virus into the saliva; culture of peripheral blood mononuclear cells from two of these patients showed no detectable regression induced by T cells that was specific to EB virus. No differences were found between the patients with and without lymphadenopathy. Peripheral blood B cells from six patients with hypergammaglobulinaemia were double stained for cytoplasmic immunoglobulin and EB viral nuclear antigen, and in all cases the activated B cells producing immunoglobulin did not contain EB nuclear antigen. Similarly, lymph node biopsy specimens from five patients showed no cells with EB nuclear antigen. These results indicate that although homosexual men have a high incidence of reactivated infection with EB virus, this viral infection is not the cause of the polyclonal activation of B cells seen in peripheral blood and is not implicated in the aetiology of the lymphadenopathy found in these men.</p>","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 4","pages":"258-64"},"PeriodicalIF":0.0,"publicationDate":"1984-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.4.258","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17392890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enzyme linked immunosorbent assay for detecting antibody to Trichomonas vaginalis: use of whole cells and aqueous extract as antigen.","authors":"J F Alderete","doi":"10.1136/sti.60.3.164","DOIUrl":"https://doi.org/10.1136/sti.60.3.164","url":null,"abstract":"<p><p>An enzyme linked immunosorbent assay (ELISA) for detecting antibody to antigenic Trichomonas vaginalis macromolecules has been identified using whole cells or an aqueous protein extract as antigen. The test was developed under optimum conditions using serum samples from experimental animals. The sensitivity of the ELISA was equal to or greater than that obtained by radioimmunoprecipitation and electrophoresis-fluorography techniques. The ELISA was capable of assessing antibody responses during the development of lesions in animals inoculated subcutaneously and it reproducibly measured the individual classes immunoglobulins directed at T vaginalis. The colorimetric assay was also suitable for showing cross reactivity between trichomonal species as well as between different strains of T vaginalis. Conditions established for monitoring antibody to trichomanads in immunised rabbits or infected mice were equally effective for human materials, such as serum or vaginal washes. Serum from experimental animals or infected people showed high concentrations of IgG, IgA, and IgM antibody to trichomonads. Only antibodies of the IgG and IgA class were detected in vaginal washes from women with acute trichomoniasis. No IgE antibody to trichomonads was found under a variety of conditions in serum samples from patients or experimental animals.</p>","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 3","pages":"164-70"},"PeriodicalIF":0.0,"publicationDate":"1984-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.3.164","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17666639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Buschke-Loewenstein tumour and laser treatment.","authors":"A Ingber, M H Grunwald, E J Feuerman","doi":"10.1136/sti.60.3.205-a","DOIUrl":"https://doi.org/10.1136/sti.60.3.205-a","url":null,"abstract":"","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 3","pages":"205-6"},"PeriodicalIF":0.0,"publicationDate":"1984-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.3.205-a","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17786613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Carriage of intestinal protozoal cysts in homosexuals.","authors":"A T Chin, A Gerken","doi":"10.1136/sti.60.3.193","DOIUrl":"https://doi.org/10.1136/sti.60.3.193","url":null,"abstract":"<p><p>A total of 83 male homosexuals were studied to ascertain the carriage of intestinal protozoal cysts. The homosexual group had a significantly (p less than 0.0005) higher prevalence than a control group. One or more types of protozoa were found in 33 homosexuals. The carriage of intestinal protozoal cysts was associated with particular sexual practices and promiscuity, but not with symptomatic bowel disorders. The possible implications of the carriage of these cysts are discussed.</p>","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 3","pages":"193-5"},"PeriodicalIF":0.0,"publicationDate":"1984-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.3.193","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17786611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}