The British Journal of Venereal Diseases最新文献_第2页

Attachment of Treponema pallidum to fibronectin, laminin, collagen IV, and collagen I, and blockage of attachment by immune rabbit IgG. 梅毒螺旋体附着于纤维连接蛋白、层粘连蛋白、IV型胶原和I型胶原，并被免疫兔IgG阻断。

The British Journal of Venereal Diseases Pub Date : 1984-12-01 DOI: 10.1136/sti.60.6.357

T J Fitzgerald, L A Repesh, D R Blanco, J N Miller

{"title":"Attachment of Treponema pallidum to fibronectin, laminin, collagen IV, and collagen I, and blockage of attachment by immune rabbit IgG.","authors":"T J Fitzgerald, L A Repesh, D R Blanco, J N Miller","doi":"10.1136/sti.60.6.357","DOIUrl":"https://doi.org/10.1136/sti.60.6.357","url":null,"abstract":"As shown by scanning electron and phase contrast microscopy, Treponema pallidum attached in vitro to basement membranes purified from kidney cortex tissues or from retinal vessels. This organism also attached to the extracellular matrix remaining after cultured cells had been solubilised with Triton X. Fibronectin, laminin, collagen, IV, collagen I, and hyaluronic acid are structural components of basement membranes and extracellular matrices. Experiments were performed to investigate the in vitro attachment of T pallidum to each of these components. Viable or heat inactivated treponemes were added to glass coverslips precoated with different concentrations of each component. After various times of incubation, coverslips were washed and the attached organisms were counted. Large numbers of viable organisms attached to each of these five components. In contrast, heat inactivation sharply reduced numbers of attached organisms. The IgG fractions of immune and non-immune rabbit serum samples were affinity purified using protein A. T pallidum was preincubated with both fractions, then incubated with either intact cultured cells or with coverslips coated with the five tissue components. The IgG from immune serum blocked treponemal attachment to the cultured cells and to fibronectin, laminin, collagen IV, and collagen I, but not to hyaluronic acid. These results are discussed in terms of attachment mechanisms of T pallidum and potential applications to in vivo infection.","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 6","pages":"357-63"},"PeriodicalIF":0.0,"publicationDate":"1984-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.6.357","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17453943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 82

Penicillin concentrations in serum and cerebrospinal fluid after intramuscular injection of aqueous procaine penicillin 0.6 MU with and without probenecid. 肌内注射普鲁卡因青霉素0.6 MU水溶液后血清和脑脊液中青霉素的浓度。

The British Journal of Venereal Diseases Pub Date : 1984-12-01 DOI: 10.1136/sti.60.6.371

B T Goh, G W Smith, L Samarasinghe, V Singh, K S Lim

引用次数: 28

Erythromycin stearate in treating chlamydial infection of the cervix. 硬脂酸红霉素治疗宫颈衣原体感染。

The British Journal of Venereal Diseases Pub Date : 1984-12-01 DOI: 10.1136/sti.60.6.387

J M Hunter, R G Sommerville

引用次数: 8

Risk of ectopic pregnancy after salpingitis. 输卵管炎后异位妊娠的风险。

The British Journal of Venereal Diseases Pub Date : 1984-12-01 DOI: 10.1136/sti.60.6.409

J C Hockin

引用次数: 0

Treponema pallidum specific IgM haemagglutination test for serodiagnosis of syphilis. 梅毒螺旋体特异性IgM血凝试验诊断梅毒。

The British Journal of Venereal Diseases Pub Date : 1984-12-01 DOI: 10.1136/sti.60.6.364

T Sato, E Kubo, M Yokota, T Kayashima, T Tomizawa

引用次数: 6

Buschke-Loewenstein tumour of the penis 阴茎的布施克-洛温斯坦瘤

The British Journal of Venereal Diseases Pub Date : 1984-10-01 DOI: 10.1136/sti.60.5.351-a

J. M. Harvey, G. Watson

引用次数: 3

Antimicrobial susceptibility of Neisseria gonorrhoeae isolated in Durban, South Africa. 南非德班分离的淋病奈瑟菌的抗菌药物敏感性。

The British Journal of Venereal Diseases Pub Date : 1984-10-01 DOI: 10.1136/sti.60.5.306

Y M Coovadia, A Kharsany, U Ramsaroop

{"title":"Antimicrobial susceptibility of Neisseria gonorrhoeae isolated in Durban, South Africa.","authors":"Y M Coovadia, A Kharsany, U Ramsaroop","doi":"10.1136/sti.60.5.306","DOIUrl":"https://doi.org/10.1136/sti.60.5.306","url":null,"abstract":"One hundred and forty clinical isolates of Neisseria gonorrhoeae were screened for production of penicillinase by the intralactam strip method and chromogenic cephalosporin test. Minimum inhibitory concentrations (MICs) of penicillin, ampicillin, tetracycline, cefoxitin, cefuroxime, cefotaxime, sulphamethoxazole-trimethoprim (ratio 19/1), and spectinomycin, were measured for 100 strains by the agar dilution method. Seven (5%) of the 140 isolates were identified as penicillinase producing N gonorrhoeae (PPNG). The MICs of penicillin for the seven PPNG strains ranged from 0 X 25 mg/1 to 2 mg/1. Of the 93 non-PPNG strains, 80 (86%) were fully susceptible to penicillin with MICs ranging from 0 X 0037 mg/1 to 0 X 06 mg/1 and 13 (14%) were of intermediate penicillin resistance with MICs greater than or equal to 0 X 125 mg/1. Of the 100 isolates tested, 86% were fully susceptible to tetracycline with MICs of less than 1 mg/1. No spectinomycin resistant strains were encountered in this study. All gonococcal strains were susceptible to the cephalosporins tested as well as to sulphamethoxazole-trimethoprim.","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 5","pages":"306-8"},"PeriodicalIF":0.0,"publicationDate":"1984-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.5.306","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17158562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Use of air dried vaginal specimens in the diagnosis of candidiasis and anaerobic vaginosis (non-specific vaginitis): effects of storage at room temperature. 使用风干阴道标本诊断念珠菌病和厌氧阴道炎(非特异性阴道炎):在室温下储存的效果。

The British Journal of Venereal Diseases Pub Date : 1984-10-01 DOI: 10.1136/sti.60.5.350-a

A Blackwell, D Barlow

{"title":"Use of air dried vaginal specimens in the diagnosis of candidiasis and anaerobic vaginosis (non-specific vaginitis): effects of storage at room temperature.","authors":"A Blackwell, D Barlow","doi":"10.1136/sti.60.5.350-a","DOIUrl":"https://doi.org/10.1136/sti.60.5.350-a","url":null,"abstract":"1. Klehr NW, Klehr J. The treatment of uncomplicated gonorrhoea with rosoxacin. Therapiewoche 1982;32:5360-3. 2. Handfield HH, Judson FN, Holmes KK. Treatment of uncomplicated gonorrhoea with roxoxacin. Antimicrobial Agents Chemother 1981; 20:625-9. 3. Bataillard JF. Acrosoxacin in the treatment of female uncomplicated gonococcal disease. Theorie et Pratique Therapeutiques 1982; 16:39-44. 4. Dolivo M. A new treatment for recent acute uncomplicated gonococcal disease. Gazette Medicales de France 1982;89:3473-5. 5. Soendjojo A, Hudiondo H, Idajadi A, Barakbah Y. Rosoxacin, a new agent for the treatment of gonorrhoea. Asian Journal of Clinical Sciences 1982;3:34-6. 6. Calubiran OV, Crisologo-Vizconde LB, Tupasi TE, Torres CA, Limson BM. Treatment of uncomplicated gonorrhoea in women. Comparison of rosoxacin and spectinomycin. Br J Vener Dis 1982;58: 231-5. 7. Harrison WO, Wignall FS, Kerbs SBJ, Berg SW. Oral rosoxacin for the treatment of penicillin resistant gonorrhoea. Lancet 1984; i: 566-7. 8. Walsh RJ, Scott R, Bittiner JB, Shahiddullah M, Slack RCB. Acrosoxacin in the treatment of uncomplicated gonorrhoea. Br J Vener Dis 1983;59:2424. 9. Romanowski B, Austin TW, Pattison FLM, et al. Rosoxacin in the therapy of uncomplicated gonorrhoea. Antimicrobial Agents Chemother 1984;25:455-7. 10. Anonymous. Acrosoxacin for gonorrhoea. Drug Ther Bull 1982;20:10-1.","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 5","pages":"350-1"},"PeriodicalIF":0.0,"publicationDate":"1984-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.5.350-a","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17545584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Fifth Harrison lecture 1984: the development of a specialty. 1984年第五次哈里森讲座:专业的发展。

The British Journal of Venereal Diseases Pub Date : 1984-10-01 DOI: 10.1136/sti.60.5.337

R D Catterall

引用次数: 2

Endemic non-venereal syphilis (bejel) in Saudi Arabia. 沙特阿拉伯地方性非性梅毒(bejel)。

The British Journal of Venereal Diseases Pub Date : 1984-10-01 DOI: 10.1136/sti.60.5.293

J L Pace, G W Csonka

引用次数: 24