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Fat and Lipid Metabolism and the Involvement of Apolipoprotein E in Alzheimer's Disease 脂质代谢和载脂蛋白E在阿尔茨海默病中的作用
Neurodegeneration and Alzheimer's Disease Pub Date : 2019-05-11 DOI: 10.1002/9781119356752.CH7
E. Hone, Florence Lim, I. Martins
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引用次数: 4
Inflammation in Alzheimer's Disease, and Prevention with Antioxidants and Phenolic Compounds - What Are the Most Promising Candidates? 阿尔茨海默病的炎症，以及抗氧化剂和酚类化合物的预防——哪些是最有希望的候选者?
Neurodegeneration and Alzheimer's Disease Pub Date : 2019-05-11 DOI: 10.1002/9781119356752.CH8
M. Sharman, G. Verdile, S. Kirubakaran, G. Münch
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引用次数: 5
Alzheimer's Disease and Other Neurodegenerative Diseases 阿尔茨海默病和其他神经退行性疾病
Neurodegeneration and Alzheimer's Disease Pub Date : 2019-05-11 DOI: 10.1002/9781119356752.CH2
S. Fuller, H. Sohrabi, Kathryn Goozee, A. Sankaranarayanan, R. Martins
{"title":"Alzheimer's Disease and Other Neurodegenerative Diseases","authors":"S. Fuller, H. Sohrabi, Kathryn Goozee, A. Sankaranarayanan, R. Martins","doi":"10.1002/9781119356752.CH2","DOIUrl":"https://doi.org/10.1002/9781119356752.CH2","url":null,"abstract":"Neurodegenerative diseases are a heterogeneous group of disorders or conditions characterised by the progressive degeneration of the structure and function of the central nervous system or the peripheral nervous system. Some are considered to be caused by protein misfolding, some involve disruptions to intracellular processes such as mitochondrial function or protein degradation pathways, and some are genetic in origin. Whatever the original cause of the disease, the greatest risk factor for most of these diseases is increasing age. This book is mostly focused on Alzheimer's disease (AD), yet in this chapter we describe Alzheimer's as well as other major neurodegenerative conditions to demonstrate both similarities and differences.","PeriodicalId":222038,"journal":{"name":"Neurodegeneration and Alzheimer's Disease","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131297221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Cognitive Impairments in Alzheimer's Disease and Other Neurodegenerative Diseases 阿尔茨海默病和其他神经退行性疾病的认知障碍
Neurodegeneration and Alzheimer's Disease Pub Date : 2019-05-11 DOI: 10.1002/9781119356752.CH9
H. Sohrabi, M. Weinborn
{"title":"Cognitive Impairments in Alzheimer's Disease and Other Neurodegenerative Diseases","authors":"H. Sohrabi, M. Weinborn","doi":"10.1002/9781119356752.CH9","DOIUrl":"https://doi.org/10.1002/9781119356752.CH9","url":null,"abstract":"This chapter discusses some of the neurocognitive deficits experienced in the Alzheimer's disease (AD) conditions, with the primary focus on different stages of dementia due to AD. It discusses the cognitive functions affected during the natural course of AD and other neurodegenerative diseases. The chapter discusses the most common neurocognitive features of AD as well as other common types of dementias. Attention and working memory deficits are commonly seen in AD patients. Following the amnestic phase of AD, attention is the second cognitive function to be affected, long before difficulties with other cognitive functions including language and praxis. There is a gradual major shift in cognitive and clinical examination, using online and computerised measures. The traditional neuropsychological approach of 'in‐person' testing should adapt and make use of such an unprecedented approach that can bring big‐data available for clinical practice, establishing psychometric basis of the available measures, and providing an avenue to develop new measures.","PeriodicalId":222038,"journal":{"name":"Neurodegeneration and Alzheimer's Disease","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126076088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Current and Prospective Treatments for Alzheimer's Disease (and Other Neurodegenerative Diseases) 阿尔茨海默病(以及其他神经退行性疾病)的当前和未来治疗方法
Neurodegeneration and Alzheimer's Disease Pub Date : 2019-05-11 DOI: 10.1002/9781119356752.CH14
S. Pedrini, M. Morici, R. Martins
{"title":"Current and Prospective Treatments for Alzheimer's Disease (and Other Neurodegenerative Diseases)","authors":"S. Pedrini, M. Morici, R. Martins","doi":"10.1002/9781119356752.CH14","DOIUrl":"https://doi.org/10.1002/9781119356752.CH14","url":null,"abstract":"","PeriodicalId":222038,"journal":{"name":"Neurodegeneration and Alzheimer's Disease","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130725678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Final Thoughts Regarding Alzheimer's Disease, Diet, and Health 关于阿尔茨海默病、饮食和健康的最后想法
Neurodegeneration and Alzheimer's Disease Pub Date : 2019-05-11 DOI: 10.1002/9781119356752.OTH1
C. Brennan, M. Brennan, W. Fernando, S. Fuller, R. Martins
{"title":"Final Thoughts Regarding Alzheimer'\u0000s Disease, Diet, and Health","authors":"C. Brennan, M. Brennan, W. Fernando, S. Fuller, R. Martins","doi":"10.1002/9781119356752.OTH1","DOIUrl":"https://doi.org/10.1002/9781119356752.OTH1","url":null,"abstract":"","PeriodicalId":222038,"journal":{"name":"Neurodegeneration and Alzheimer's Disease","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125977084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Products of Fermentation and Their Effects on Metabolism, Alzheimer's Disease, and Other Neurodegenerative Diseases: Role of Short-Chain Fatty Acids (SCFA) 发酵产物及其对代谢、阿尔茨海默病和其他神经退行性疾病的影响:短链脂肪酸(SCFA)的作用
Neurodegeneration and Alzheimer's Disease Pub Date : 2019-05-11 DOI: 10.1002/9781119356752.CH11
W. Fernando, C. Brennan, R. Martins
{"title":"The Products of Fermentation and Their Effects on Metabolism, Alzheimer's Disease, and Other Neurodegenerative Diseases: Role of Short-Chain Fatty Acids (SCFA)","authors":"W. Fernando, C. Brennan, R. Martins","doi":"10.1002/9781119356752.CH11","DOIUrl":"https://doi.org/10.1002/9781119356752.CH11","url":null,"abstract":"","PeriodicalId":222038,"journal":{"name":"Neurodegeneration and Alzheimer's Disease","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121797339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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